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Volumn 85, Issue 6, 2011, Pages 345-351

Dietary long-chain n-3 PUFA, gut microbiota and fat mass in early postnatal piglet development-exploring a potential interplay

Author keywords

Adiposity; Fish oil; Gut bacterial composition; Infants; Pigs

Indexed keywords

OMEGA 3 FATTY ACID;

EID: 80055098498     PISSN: 09523278     EISSN: 15322823     Source Type: Journal    
DOI: 10.1016/j.plefa.2011.08.004     Document Type: Article
Times cited : (23)

References (53)
  • 2
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley R.E., Turnbaugh P.J., Klein S., Gordon J.I. Microbial ecology: human gut microbes associated with obesity. Nature 2006, 444:1022-1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 3
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh P.J., Ley R.E., Mahowald M.A., Magrini V., Mardis E.R., Gordon J.I. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444:1027-1131.
    • (2006) Nature , vol.444 , pp. 1027-1131
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 5
    • 54249110955 scopus 로고    scopus 로고
    • Development of a real-time PCR method for Firmicutes and Bacteroidetes in faeces and its application to quantify intestinal population of obese and lean pigs
    • Guo X., Xia X., Tang R., Zhou J., Zhao H., Wang K. Development of a real-time PCR method for Firmicutes and Bacteroidetes in faeces and its application to quantify intestinal population of obese and lean pigs. Letters in Applied Microbiology 2008, 47:367-373.
    • (2008) Letters in Applied Microbiology , vol.47 , pp. 367-373
    • Guo, X.1    Xia, X.2    Tang, R.3    Zhou, J.4    Zhao, H.5    Wang, K.6
  • 8
    • 0032771771 scopus 로고    scopus 로고
    • Coordinate induction of peroxisomal acyl-CoA oxidase and UCP-3 by dietary fish oil: a mechanism for decreased body fat deposition
    • Baillie R.A., Takada R., Nakamura M., Clarke S.D. Coordinate induction of peroxisomal acyl-CoA oxidase and UCP-3 by dietary fish oil: a mechanism for decreased body fat deposition. Prostaglandins, Leukotrienes and Essential Fatty Acids 1999, 60:351-356.
    • (1999) Prostaglandins, Leukotrienes and Essential Fatty Acids , vol.60 , pp. 351-356
    • Baillie, R.A.1    Takada, R.2    Nakamura, M.3    Clarke, S.D.4
  • 9
    • 80055082302 scopus 로고    scopus 로고
    • Reduction of adiposity in C57BL/6J mice by dietary omega-3 polyunsaturated fatty acids of marine origin
    • Ruzickova J., Rossmeisl M., Flachs P., et al. Reduction of adiposity in C57BL/6J mice by dietary omega-3 polyunsaturated fatty acids of marine origin. Diabetologia 2004, 47:662.
    • (2004) Diabetologia , vol.47 , pp. 662
    • Ruzickova, J.1    Rossmeisl, M.2    Flachs, P.3
  • 10
    • 34247558036 scopus 로고    scopus 로고
    • Eicosapentaenoic acid actions on adiposity and insulin resistance in control and high-fat-fed rats: role of apoptosis, adiponectin and tumour necrosis factor-alpha
    • Perez-Matute P., Perez-Echarri N., Martinez J.A., Marti A., Moreno-Aliaga M.J. Eicosapentaenoic acid actions on adiposity and insulin resistance in control and high-fat-fed rats: role of apoptosis, adiponectin and tumour necrosis factor-alpha. British Journal of Nutrition 2007, 97:389-398.
    • (2007) British Journal of Nutrition , vol.97 , pp. 389-398
    • Perez-Matute, P.1    Perez-Echarri, N.2    Martinez, J.A.3    Marti, A.4    Moreno-Aliaga, M.J.5
  • 11
    • 37149051585 scopus 로고    scopus 로고
    • Dietary fish oil upregulates intestinal lipid metabolism and reduces body weight gain in C57BL/6J mice
    • Mori T., Kondo H., Hase T., Tokimitsu I., Murase T. Dietary fish oil upregulates intestinal lipid metabolism and reduces body weight gain in C57BL/6J mice. Journal of Nutrition 2007, 137:2629-2634.
    • (2007) Journal of Nutrition , vol.137 , pp. 2629-2634
    • Mori, T.1    Kondo, H.2    Hase, T.3    Tokimitsu, I.4    Murase, T.5
  • 12
    • 49649107853 scopus 로고    scopus 로고
    • An emerging risk factor for obesity: does disequilibrium of polyunsaturated fatty acid metabolism contribute to excessive adipose tissue development?
    • Ailhaud G., Guesnet P., Cunnane S.C. An emerging risk factor for obesity: does disequilibrium of polyunsaturated fatty acid metabolism contribute to excessive adipose tissue development?. British Journal of Nutrition 2008, 100:461-470.
    • (2008) British Journal of Nutrition , vol.100 , pp. 461-470
    • Ailhaud, G.1    Guesnet, P.2    Cunnane, S.C.3
  • 13
    • 73349085284 scopus 로고    scopus 로고
    • Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity
    • Micallef M., Munro I., Phang M., Garg M. Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity. British Journal of Nutrition 2009, 102:1370-1374.
    • (2009) British Journal of Nutrition , vol.102 , pp. 1370-1374
    • Micallef, M.1    Munro, I.2    Phang, M.3    Garg, M.4
  • 14
    • 30644474722 scopus 로고    scopus 로고
    • Composition of porcine milk
    • Nottingham University Press, R.J. Xu, P.D. Cranwell (Eds.)
    • Xu R.J. Composition of porcine milk. The Neonatal Pig 2003, Nottingham University Press, pp. 213-247. R.J. Xu, P.D. Cranwell (Eds.).
    • (2003) The Neonatal Pig , pp. 213-247
    • Xu, R.J.1
  • 15
    • 0030066046 scopus 로고    scopus 로고
    • Evaluation of dual-energy X-ray absorptiometry for body-composition assessment in piglets and term human neonates
    • Picaud J.C., Rigo J., Nyamugabo K., Milet J., Senterre J. Evaluation of dual-energy X-ray absorptiometry for body-composition assessment in piglets and term human neonates. American Journal of Clinical Nutrition 1996, 63:157-163.
    • (1996) American Journal of Clinical Nutrition , vol.63 , pp. 157-163
    • Picaud, J.C.1    Rigo, J.2    Nyamugabo, K.3    Milet, J.4    Senterre, J.5
  • 16
    • 2942598786 scopus 로고    scopus 로고
    • Maternal fish oil supplementation in lactation: effect on visual acuity and n-3 fatty acid content of infant erythrocytes
    • Lauritzen L., Jorgensen M., Mikkelsen T., et al. Maternal fish oil supplementation in lactation: effect on visual acuity and n-3 fatty acid content of infant erythrocytes. Lipids 2004, 39:195-206.
    • (2004) Lipids , vol.39 , pp. 195-206
    • Lauritzen, L.1    Jorgensen, M.2    Mikkelsen, T.3
  • 17
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J., Lees M., Stanley G.H.S. A simple method for the isolation and purification of total lipides from animal tissues. Journal of Biological Chemistry 1957, 226:497-509.
    • (1957) Journal of Biological Chemistry , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Stanley, G.H.S.3
  • 18
    • 85010249766 scopus 로고
    • Preparation of milk fat methyl esters by alcoholysis in an essentially nonalcoholic solution
    • Christopherson S.W., Glass R.L. Preparation of milk fat methyl esters by alcoholysis in an essentially nonalcoholic solution. Journal of Dairy Science 1969, 52:1289-1290.
    • (1969) Journal of Dairy Science , vol.52 , pp. 1289-1290
    • Christopherson, S.W.1    Glass, R.L.2
  • 19
    • 35449000162 scopus 로고    scopus 로고
    • Increased amount of Bifidobacterium thermacidophilum and Megasphaera elsdenii in the colonic microbiota of pigs fed a swine dysentery preventive diet containing chicory roots and sweet lupine
    • Molbak L., Thomsen L.E., Jensen T.K., Knudsen K.E.B., Boye M. Increased amount of Bifidobacterium thermacidophilum and Megasphaera elsdenii in the colonic microbiota of pigs fed a swine dysentery preventive diet containing chicory roots and sweet lupine. Journal of Applied Microbiology 2007, 103:1853-1867.
    • (2007) Journal of Applied Microbiology , vol.103 , pp. 1853-1867
    • Molbak, L.1    Thomsen, L.E.2    Jensen, T.K.3    Knudsen, K.E.B.4    Boye, M.5
  • 20
    • 0036841520 scopus 로고    scopus 로고
    • Development of 16S rRNA-gene-targeted group-specific primers for the detection and identification of predominant bacteria in human feces
    • Matsuki T., Watanabe K., Fujimoto J., et al. Development of 16S rRNA-gene-targeted group-specific primers for the detection and identification of predominant bacteria in human feces. Applied and Environmental Microbiology 2002, 68:5445-5451.
    • (2002) Applied and Environmental Microbiology , vol.68 , pp. 5445-5451
    • Matsuki, T.1    Watanabe, K.2    Fujimoto, J.3
  • 21
    • 34248571862 scopus 로고    scopus 로고
    • MiCA: a web-based tool for the analysis of microbial communities based on terminal-restriction fragment length polymorphisms of 16S and 18S rRNA genes
    • Shyu C., Soule T., Bent S., Foster J., Forney L. MiCA: a web-based tool for the analysis of microbial communities based on terminal-restriction fragment length polymorphisms of 16S and 18S rRNA genes. Microbial Ecology 2007, 53:562-570.
    • (2007) Microbial Ecology , vol.53 , pp. 562-570
    • Shyu, C.1    Soule, T.2    Bent, S.3    Foster, J.4    Forney, L.5
  • 22
    • 0028881751 scopus 로고
    • Impact of polyunsaturated fatty-acids on human colonic bacterial metabolism-an in-vitro and in-vivo study
    • Thompson L., Spiller R.C. Impact of polyunsaturated fatty-acids on human colonic bacterial metabolism-an in-vitro and in-vivo study. British Journal of Nutrition 1995, 74:733-741.
    • (1995) British Journal of Nutrition , vol.74 , pp. 733-741
    • Thompson, L.1    Spiller, R.C.2
  • 24
  • 25
    • 0037827089 scopus 로고    scopus 로고
    • The influence of omega-3 polyunsaturated fatty acids (omega-3 pufa) on lactobacilli adhesion to the intestinal mucosa and on immunity in gnotobiotic piglets
    • July-August
    • Bomba A., Nemcova R., Gancarcikova S., et al. The influence of omega-3 polyunsaturated fatty acids (omega-3 pufa) on lactobacilli adhesion to the intestinal mucosa and on immunity in gnotobiotic piglets. Berl Munch Tierarztl Wochenschr 2003, 116(7-8):312-316. July-August.
    • (2003) Berl Munch Tierarztl Wochenschr , vol.116 , Issue.7-8 , pp. 312-316
    • Bomba, A.1    Nemcova, R.2    Gancarcikova, S.3
  • 26
    • 0031740150 scopus 로고    scopus 로고
    • The effect of dietary fatty acids on lactic acid bacteria associated with the epithelial mucosa and from faecalia of Arctic charr, Salvelinus alpinus (L.)
    • Ringo E., Bendiksen H.R., Gausen S.J., Sundsfjord A., Olsen R.E. The effect of dietary fatty acids on lactic acid bacteria associated with the epithelial mucosa and from faecalia of Arctic charr, Salvelinus alpinus (L.). Journal of Applied Microbiology 1998, 85:855-864.
    • (1998) Journal of Applied Microbiology , vol.85 , pp. 855-864
    • Ringo, E.1    Bendiksen, H.R.2    Gausen, S.J.3    Sundsfjord, A.4    Olsen, R.E.5
  • 27
    • 70350315756 scopus 로고    scopus 로고
    • Dietary omega-3 polyunsaturated fatty acid does not influence the intestinal microbial communities of broiler chickens
    • Geier M.S., Torok V.A., Allison G.E., et al. Dietary omega-3 polyunsaturated fatty acid does not influence the intestinal microbial communities of broiler chickens. Poultry Science 2009, 88:2399-2405.
    • (2009) Poultry Science , vol.88 , pp. 2399-2405
    • Geier, M.S.1    Torok, V.A.2    Allison, G.E.3
  • 29
    • 0027215407 scopus 로고
    • Fish-oil n-3 fatty-acids selectively limit the hypertrophy of abdominal fat depots in growing rats fed high-fat diets
    • Belzung F., Raclot T., Groscolas R. Fish-oil n-3 fatty-acids selectively limit the hypertrophy of abdominal fat depots in growing rats fed high-fat diets. American Journal of Physiology 1993, 264:R1111-R1118.
    • (1993) American Journal of Physiology , vol.264
    • Belzung, F.1    Raclot, T.2    Groscolas, R.3
  • 30
    • 0033844398 scopus 로고    scopus 로고
    • Dietary n-3 fatty acids affect mRNA level of brown adipose tissue uncoupling protein 1, and white adipose tissue leptin and glucose transporter 4 in the rat
    • Takahashi Y., Ide T. Dietary n-3 fatty acids affect mRNA level of brown adipose tissue uncoupling protein 1, and white adipose tissue leptin and glucose transporter 4 in the rat. British Journal of Nutrition 2000, 84:175-184.
    • (2000) British Journal of Nutrition , vol.84 , pp. 175-184
    • Takahashi, Y.1    Ide, T.2
  • 32
    • 0033609292 scopus 로고    scopus 로고
    • Increased uncoupling protein2 mRNA in white adipose tissue, and decrease in leptin, visceral fat, blood glucose, and cholesterol in KK-A(y) mice fed with eicosapentaenoic and docosahexaenoic acids in addition to linolenic acid
    • Hun C.S., Hasegawa K., Kawabata T., Kato M., Shimokawa T., Kagawa Y. Increased uncoupling protein2 mRNA in white adipose tissue, and decrease in leptin, visceral fat, blood glucose, and cholesterol in KK-A(y) mice fed with eicosapentaenoic and docosahexaenoic acids in addition to linolenic acid. Biochemical and Biophysical Research Communications 1999, 259:85-90.
    • (1999) Biochemical and Biophysical Research Communications , vol.259 , pp. 85-90
    • Hun, C.S.1    Hasegawa, K.2    Kawabata, T.3    Kato, M.4    Shimokawa, T.5    Kagawa, Y.6
  • 33
    • 0037356682 scopus 로고    scopus 로고
    • Role of dietary fat type in the development of adiposity from dietary obesity-susceptible Sprague? Dawley rats
    • Jang I.S., Hwang D.Y., Chae K.R., et al. Role of dietary fat type in the development of adiposity from dietary obesity-susceptible Sprague? Dawley rats. British Journal of Nutrition 2003, 89:429-437.
    • (2003) British Journal of Nutrition , vol.89 , pp. 429-437
    • Jang, I.S.1    Hwang, D.Y.2    Chae, K.R.3
  • 34
    • 34249812073 scopus 로고    scopus 로고
    • Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids
    • Huber J., Loffler M., Bilban M., et al. Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids. International Journal of Obesity 2007, 31:1004-1013.
    • (2007) International Journal of Obesity , vol.31 , pp. 1004-1013
    • Huber, J.1    Loffler, M.2    Bilban, M.3
  • 35
    • 0742271970 scopus 로고    scopus 로고
    • Role of fat amount and type in ameliorating diet-induced obesity: insights at the level of hypothalamic arcuate nucleus leptin receptor, neuropeptide Y and pro-opiomelanocortin mRNA expression
    • Huang X.F., Xin X., McLennan P., Storlien L. Role of fat amount and type in ameliorating diet-induced obesity: insights at the level of hypothalamic arcuate nucleus leptin receptor, neuropeptide Y and pro-opiomelanocortin mRNA expression. Diabetes Obesity & Metabolism 2004, 6:35-44.
    • (2004) Diabetes Obesity & Metabolism , vol.6 , pp. 35-44
    • Huang, X.F.1    Xin, X.2    McLennan, P.3    Storlien, L.4
  • 36
    • 33746772121 scopus 로고    scopus 로고
    • Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids
    • Todoric J., Loffler M., Huber J., et al. Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids. Diabetologia 2006, 49:2109-2119.
    • (2006) Diabetologia , vol.49 , pp. 2109-2119
    • Todoric, J.1    Loffler, M.2    Huber, J.3
  • 37
    • 67650742259 scopus 로고    scopus 로고
    • Dietary n-3-polyunsaturated fatty acids and energy balance in overweight or moderately obese men and women: a randomized controlled trial
    • Kratz M., Callahan H.S., Yang P.Y., Matthys C.C., Weigle D.S. Dietary n-3-polyunsaturated fatty acids and energy balance in overweight or moderately obese men and women: a randomized controlled trial. Nutrition and Metabolism 2009, 6.
    • (2009) Nutrition and Metabolism , vol.6
    • Kratz, M.1    Callahan, H.S.2    Yang, P.Y.3    Matthys, C.C.4    Weigle, D.S.5
  • 38
    • 33749130207 scopus 로고    scopus 로고
    • Additive benefits of long-chain n-3 polyunsaturated fatty acids and weight-loss in the management of cardiovascular disease risk in overweight hyperinsulinaemic women
    • Krebs J.D., Browning L.M., Mclean N.K., et al. Additive benefits of long-chain n-3 polyunsaturated fatty acids and weight-loss in the management of cardiovascular disease risk in overweight hyperinsulinaemic women. International Journal of Obesity 2006, 30:1535-1544.
    • (2006) International Journal of Obesity , vol.30 , pp. 1535-1544
    • Krebs, J.D.1    Browning, L.M.2    Mclean, N.K.3
  • 39
    • 36849077566 scopus 로고    scopus 로고
    • Treatment for 2 mo with n-3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled study
    • Kabir M., Skurnik G., Naour N., et al. Treatment for 2 mo with n-3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled study. American Journal of Clinical Nutrition 2007, 86:1670-1679.
    • (2007) American Journal of Clinical Nutrition , vol.86 , pp. 1670-1679
    • Kabir, M.1    Skurnik, G.2    Naour, N.3
  • 40
    • 84950170958 scopus 로고    scopus 로고
    • Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors
    • Hill A.M., Buckley J.D., Murphy K.J., Howe P.R.C. Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors. American Journal of Clinical Nutrition 2007, 85:1267-1274.
    • (2007) American Journal of Clinical Nutrition , vol.85 , pp. 1267-1274
    • Hill, A.M.1    Buckley, J.D.2    Murphy, K.J.3    Howe, P.R.C.4
  • 41
    • 73749088581 scopus 로고    scopus 로고
    • Marine n-3 fatty acids promote size reduction of visceral adipose depots, without altering body weight and composition, in male Wistar rats fed a high-fat diet
    • Rokling-Andersen M.H., Rustan A.C., Wensaas A.J., et al. Marine n-3 fatty acids promote size reduction of visceral adipose depots, without altering body weight and composition, in male Wistar rats fed a high-fat diet. British Journal of Nutrition 2009, 102:995-1006.
    • (2009) British Journal of Nutrition , vol.102 , pp. 995-1006
    • Rokling-Andersen, M.H.1    Rustan, A.C.2    Wensaas, A.J.3
  • 42
    • 15644384389 scopus 로고    scopus 로고
    • Perilla oil prevents the excessive growth of visceral adipose tissue in rats by down-regulating adipocyte differentiation
    • Okuno M., Kajiwara K., Imai S., et al. Perilla oil prevents the excessive growth of visceral adipose tissue in rats by down-regulating adipocyte differentiation. Journal of Nutrition 1997, 127:1752-1757.
    • (1997) Journal of Nutrition , vol.127 , pp. 1752-1757
    • Okuno, M.1    Kajiwara, K.2    Imai, S.3
  • 43
    • 0035515242 scopus 로고    scopus 로고
    • Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women
    • Helland I.B., Saugstad O.D., Smith L., et al. Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women. Pediatrics 2001, 108:e82.
    • (2001) Pediatrics , vol.108
    • Helland, I.B.1    Saugstad, O.D.2    Smith, L.3
  • 44
    • 20544444045 scopus 로고    scopus 로고
    • Diversity of the human intestinal microbial flora
    • Eckburg P.B., Bik E.M., Bernstein C.N., et al. Diversity of the human intestinal microbial flora. Science 2005, 308:1635-1638.
    • (2005) Science , vol.308 , pp. 1635-1638
    • Eckburg, P.B.1    Bik, E.M.2    Bernstein, C.N.3
  • 45
    • 46249085739 scopus 로고    scopus 로고
    • Evolution of mammals and their gut microbes
    • Ley R.E., Hamady M., Lozupone C., et al. Evolution of mammals and their gut microbes. Science 2008, 320:1647-1651.
    • (2008) Science , vol.320 , pp. 1647-1651
    • Ley, R.E.1    Hamady, M.2    Lozupone, C.3
  • 47
    • 50849127827 scopus 로고    scopus 로고
    • Real-time PCR quantification of the predominant bacterial divisions in the distal gut of Meishan and Landrace pigs
    • Guo X.L., Xia X.J., Tang R.Y., Wang K.N. Real-time PCR quantification of the predominant bacterial divisions in the distal gut of Meishan and Landrace pigs. Anaerobe 2008, 14:224-228.
    • (2008) Anaerobe , vol.14 , pp. 224-228
    • Guo, X.L.1    Xia, X.J.2    Tang, R.Y.3    Wang, K.N.4
  • 48
    • 56549122798 scopus 로고    scopus 로고
    • Human colonic microbiota associated with diet, obesity and weight loss
    • Duncan S.H., Lobley G.E., Holtrop G., et al. Human colonic microbiota associated with diet, obesity and weight loss. International Journal of Obesity 2008, 32:1720-1724.
    • (2008) International Journal of Obesity , vol.32 , pp. 1720-1724
    • Duncan, S.H.1    Lobley, G.E.2    Holtrop, G.3
  • 49
    • 70349239142 scopus 로고    scopus 로고
    • What do we mean when we refer to Bacteroidetes populations in the human gastrointestinal microbiota?
    • Hoyles L., McCartney A.L. What do we mean when we refer to Bacteroidetes populations in the human gastrointestinal microbiota?. Fems Microbiology Letters 2009, 299:175-183.
    • (2009) Fems Microbiology Letters , vol.299 , pp. 175-183
    • Hoyles, L.1    McCartney, A.L.2
  • 51
    • 40449120742 scopus 로고    scopus 로고
    • Conjugated linoleic acid reduces body fat accretion and lipogenic gene expression in, neonatal pigs fed low- or high-fat formulas
    • Corl B.A., Oliver S.A.M., Lin X., et al. Conjugated linoleic acid reduces body fat accretion and lipogenic gene expression in, neonatal pigs fed low- or high-fat formulas. Journal of Nutrition 2008, 138:449-454.
    • (2008) Journal of Nutrition , vol.138 , pp. 449-454
    • Corl, B.A.1    Oliver, S.A.M.2    Lin, X.3
  • 53
    • 56849106496 scopus 로고    scopus 로고
    • The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
    • Dethlefsen L., Huse S., Sogin M.L., Relman D.A. The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. Plos Biology 2008, 6:2383-2400.
    • (2008) Plos Biology , vol.6 , pp. 2383-2400
    • Dethlefsen, L.1    Huse, S.2    Sogin, M.L.3    Relman, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.