Curcumin targets the TFEB-lysosome pathway for induction of autophagy

Oncotarget

Volumn 7, Issue 46, 2016, Pages 75659-75671

  Zhang, Jianbin ^a,b,c   Wang, Jigang ^b   Xu, Jian ^c   Lu, Yuanqiang ^d   Jiang, Jiukun ^d   Wang, Liming ^b   Shen, Han Ming ^b,e   Xia, Dajing ^c  

^a ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c ZHEJIANG UNIVERSITY   (China)

^d ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Autophagy; Curcumin; Lysosome; MTOR; TFEB

Indexed keywords

CURCUMIN; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN KINASE B; PROTEIN S6; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EB; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; MTOR PROTEIN, HUMAN; PROTEIN BINDING; TARGET OF RAPAMYCIN KINASE; TFEB PROTEIN, HUMAN;

ACIDIFICATION; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; CELL DEATH; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; FIBROBLAST; HCT116 CELL LINE; HUMAN; HUMAN CELL; LYSOSOME; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; GENE KNOCKOUT; GENETICS; HCT 116 CELL LINE; METABOLISM; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AUTOPHAGY; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL LINE; CELL SURVIVAL; CURCUMIN; FIBROBLASTS; GENE KNOCKOUT TECHNIQUES; HCT116 CELLS; HUMANS; LYSOSOMES; MICE; PROTEIN BINDING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSCRIPTIONAL ACTIVATION;

EID: 84996636850     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.12318     Document Type: Article

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