Somatically Hypermutated Plasmodium-Specific IgM+ Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge

Immunity

Volumn 45, Issue 2, 2016, Pages 402-414

  Krishnamurty, Akshay T ^a   Thouvenel, Christopher D ^b   Portugal, Silvia ^c   Keitany, Gladys J ^a   Kim, Karen S ^a   Holder, Anthony ^d   Crompton, Peter D ^c   Rawlings, David J ^a,b   Pepper, Marion ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d THE FRANCIS CRICK INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; IMMUNOGLOBULIN D; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MEROZOITE SURFACE PROTEIN 1; SYNDECAN 1; EPITOPE; MALARIA VACCINE; PARASITE ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY SECRETING CELL; ANTIBODY SPECIFICITY; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; CD4+ T LYMPHOCYTE; CELL EXPANSION; CELL FATE; CELL SPECIFICITY; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; LYMPHOCYTE PROLIFERATION; MALARIA; MALARIA FALCIPARUM; MEMORY CELL; MOUSE; NONHUMAN; PARASITE IMMUNITY; PHENOTYPE; PLASMA CELL; PLASMABLAST; PLASMODIUM; PLASMODIUM CHABAUDI; PLASMODIUM CHABAUDI INFECTION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SECONDARY INFECTION; SOMATIC HYPERMUTATION; ANIMAL; ANTIBODY AFFINITY; B LYMPHOCYTE; B LYMPHOCYTE SUBPOPULATION; C57BL MOUSE; CELL CULTURE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; SECONDARY IMMUNIZATION; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANIMALS; ANTIBODY AFFINITY; ANTIGENS, PROTOZOAN; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; CELLS, CULTURED; EPITOPES; FEMALE; HUMANS; IMMUNITY, HUMORAL; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN M; IMMUNOLOGIC MEMORY; MALARIA; MALARIA VACCINES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PLASMODIUM; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; T-LYMPHOCYTES;

EID: 84996554674     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.06.014     Document Type: Article

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