Minocycline suppresses NLRP3 inflammasome activation in experimental ischemic stroke

NeuroImmunoModulation

Volumn 23, Issue 4, 2017, Pages 230-238

  Lu, Yunnan ^a   Xiao, Guodong ^a   Luo, Weifeng ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

Ischemic stroke; Microglia; Minocycline; NLRP3 inflammasome

Indexed keywords

CRYOPYRIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; MINOCYCLINE; OXYGEN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR; ANTIINFECTIVE AGENT; INFLAMMASOME; NLRP3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EXPERIMENTAL ISCHEMIA; EXPERIMENTAL ISCHEMIC STROKE; GLUCOSE INTOLERANCE; IMMUNOMODULATION; IMMUNOPATHOGENESIS; IN VITRO STUDY; INFANT; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; REOXYGENATION; REPERFUSION; RISK ASSESSMENT; SIGNAL TRANSDUCTION; TRANSIENT MIDDLE CEREBRAL ARTERY OCCLUSION; TREATMENT DURATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; CEREBROVASCULAR ACCIDENT; DOSE RESPONSE; DRUG EFFECTS; METABOLISM;

ANIMALS; ANTI-BACTERIAL AGENTS; BRAIN ISCHEMIA; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; INFLAMMASOMES; MALE; MICE; MICE, INBRED C57BL; MICROGLIA; MINOCYCLINE; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; STROKE;

EID: 84995810940     PISSN: 10217401     EISSN: 14230216     Source Type: Journal    
DOI: 10.1159/000452172     Document Type: Article

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