Thiazole containing nitrogen mustards: Synthesis, structural evaluation, cytotoxicity and DNA binding studies

Letters in Drug Design and Discovery

Volumn 8, Issue 9, 2011, Pages 838-842

  Raghavendra, Nulgulmnalli Manjunathiah ^a   Renuka, Surampudi ^a   Gupta, Sayan Dutta ^a   Divya, Pingili ^a  

^a Osmania University   (India)

Author keywords

Anticancer activity; Benzothiazoles; Cytotoxicity; DNA binding; Nitrogen mustards; Thiazoles

Indexed keywords

2 [BIS(2 CHLOROETHYL)AMINO] N (5 NITROTHIAZOL 2 YL)ACETAMIDE; 2 [BIS(2 CHLOROETHYL)AMINO] N (5METHYLTHIAZOL 2 YL)ACETAMIDE; 2 [BIS(2 CHLOROETHYL)AMINO] N (6 ETHOXYBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [BIS(2 CHLOROETHYL)AMINO] N (6 METHYLBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [BIS(2 CHLOROETHYL)AMINO] N (6 NITROBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [BIS(2 CHLOROETHYL)AMINO] N (THIAZOL 2 YL)ACETAMIDE; ANTINEOPLASTIC AGENT; BENZOTHIAZOLE; CHLORMETHINE; CISPLATIN; N (2 CHLOROETHYL) 6 ETHOXYBENZO[D]THIAZOL 2 AMINE; N (2 CHLOROETHYL) 6 METHYLBENZO[D]THIAZOL 2 AMINE; N (2 CHLOROETHYL) 6 NITROBENZO[D]THIAZOL 2 AMINE; N (2 CHLOROETHYL)BENZO[D]THIAZOL 2 AMINE; N (BENZO[D]THIAZOL 2 YL) 2 [BIS(2 CHLOROETHYL)AMINO]ACETAMIDE; THIAZOLE; UNCLASSIFIED DRUG;

A549 CELL LINE; ABSORPTION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; LUNG CANCER CELL LINE; MASS SPECTROMETRY; MTT ASSAY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RESEARCH;

EID: 84995646145     PISSN: 15701808     EISSN: 1875628X     Source Type: Journal    
DOI: 10.2174/157018011797200812     Document Type: Article

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