Effect of drug solubility and lipid carrier on drug release from lipid nanoparticles for dermal delivery

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 110, Issue , 2017, Pages 39-46

  Zoubari, Gaith ^a   Staufenbiel, Sven ^a   Volz, Pierre ^a   Alexiev, Ulrike ^a   Bodmeier, Roland ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Dexamethasone; Diclofenac; In vitro drug release; Lipid nanoparticles; Microencapsulation; Nanocarrier; Single molecule detection; Total internal reflection fluorescence (TIRF) microscopy

Indexed keywords

CAPRYOL; DEXAMETHASONE; DICLOFENAC; DYNASAN; GELUCIRE; GLYCEROL PALMITOSTEARATE; IMWITOR; KOLLIWAX; MIGLYOL; NANOCARRIER; SOFTISAN; SOLID LIPID NANOPARTICLE; UNCLASSIFIED DRUG; WITEPSOL; CAPRYOL PROPYLENE GLYCOL MONOCAPRYLATE; DELAYED RELEASE FORMULATION; DRUG CARRIER; FAT; GELUCIRE 50-13; LIPID; NANOPARTICLE; OIL; POLYMER; PROPANEDIOL DERIVATIVE; SURFACTANT; TRIACYLGLYCEROL;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STRUCTURE; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; MISCIBILITY; NANOENCAPSULATION; PH; TOTAL INTERNAL REFLECTION FLUORESCENCE MICROSCOPY; CHEMISTRY; CUTANEOUS DRUG ADMINISTRATION; DELAYED RELEASE FORMULATION; DIFFERENTIAL SCANNING CALORIMETRY; DIFFUSION; DRUG STABILITY; HUMAN; PARTICLE SIZE; SOLUBILITY; TEMPERATURE; TIME FACTOR;

ADMINISTRATION, CUTANEOUS; CALORIMETRY, DIFFERENTIAL SCANNING; DELAYED-ACTION PREPARATIONS; DEXAMETHASONE; DICLOFENAC; DIFFUSION; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; DRUG STABILITY; FATS; HUMANS; HYDROGEN-ION CONCENTRATION; LIPIDS; NANOPARTICLES; OILS; PARTICLE SIZE; POLYMERS; PROPYLENE GLYCOLS; SOLUBILITY; SURFACE-ACTIVE AGENTS; TEMPERATURE; TIME FACTORS; TRIGLYCERIDES;

EID: 84994837834     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2016.10.021     Document Type: Article

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