IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain

Cell Reports

Volumn 17, Issue 4, 2016, Pages 941-948

  Bhattarai, Prabesh ^a,b   Thomas, Alvin Kuriakose ^c   Cosacak, Mehmet Ilyas ^a,b   Papadimitriou, Christos ^a,b   Mashkaryan, Violeta ^a,b   Froc, Cynthia ^d   Reinhardt, Susanne ^b,c   Kurth, Thomas ^b,c   Dahl, Andreas ^b,c   Zhang, Yixin ^c   Kizil, Caghan ^a,b  

^a GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^b CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^d CNRS   (France)

Author keywords

Alzheimer's disease; Amyloid 42; inflammation; interlukin 4; neural stem cell; neuro immune crosstalk; neurodegeneration; regeneration; STAT6; zebrafish

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; INTERLEUKIN 4; STAT6 PROTEIN; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT; PROTEIN AGGREGATE;

ADULT; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN TISSUE; CELL ACTIVATION; CELL INTERACTION; CELL PROLIFERATION; CONTROLLED STUDY; IMMUNOCOMPETENT CELL; LEARNING DISORDER; MACROPHAGE ACTIVATION; MICROGLIA; NERVE CELL PLASTICITY; NERVE DEGENERATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROTOXICITY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SYNAPTIC DEGENERATION; ZEBRA FISH; AGING; ANIMAL; BRAIN; CELL PLASTICITY; CYTOLOGY; METABOLISM; NERVE CELL; PATHOLOGY; PHENOTYPE; SIGNAL TRANSDUCTION;

AGING; AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN; CELL PLASTICITY; CELL PROLIFERATION; INTERLEUKIN-4; MICROGLIA; NERVE DEGENERATION; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; PEPTIDE FRAGMENTS; PHENOTYPE; PROTEIN AGGREGATES; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR; ZEBRAFISH;

EID: 84994807615     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.09.075     Document Type: Article

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