Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway

Nature

Volumn 539, Issue 7627, 2016, Pages 102-106

  Yu, Yong ^a   Tsang, Jason C H ^a,b,c   Wang, Cui ^a,d   Clare, Simon ^a   Wang, Juexuan ^a   Chen, Xi ^a   Brandt, Cordelia ^a   Kane, Leanne ^a   Campos, Lia S ^a   Lu, Liming ^e   Belz, Gabrielle T ^f,g   McKenzie, Andrew N J ^h   Teichmann, Sarah A ^a,i   Dougan, Gordon ^a,j   Liu, Pentao ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^d INSTITUTE OF EDIBLE FUNGI   (China)

^e SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^f WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^g UNIVERSITY OF MELBOURNE   (Australia)

^h MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

ⁱ WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^j UNIVERSITY OF CAMBRIDGE   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BCL11A PROTEIN; CELL SURFACE MARKER; CYTOKINE RECEPTOR; INHIBITOR OF DIFFERENTIATION 2; INTERLEUKIN 13; INTERLEUKIN 25; INTERLEUKIN 5; NOTCH1 RECEPTOR; OSTEOGENIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROGRAMMED DEATH 1 LIGAND 1; SMALL CYTOPLASMIC RNA; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR 7; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR HES 1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ANTIBODY; BCL11B PROTEIN, MOUSE; CYTOKINE; INTERLEUKIN RECEPTOR; PDCD1 PROTEIN, MOUSE; PROGRAMMED DEATH 1 RECEPTOR; REPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANTIBODY; ANTIGEN; BLOOD; BONE; CELLS AND CELL COMPONENTS; HOMEOSTASIS; IMMUNE SYSTEM; INFLUENZA; LIGAND; RODENT; TOXICITY;

ADOPTIVE TRANSFER; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL ACTIVATION; CELL ISOLATION; CELL LINEAGE; CELL SUBPOPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEVELOPMENTAL STAGE; DOWN REGULATION; FLOW CYTOMETRY; GENE IDENTIFICATION; GENE OVEREXPRESSION; INFLUENZA; LUNG PARENCHYMA; LYMPHOID CELL; LYMPHOID PROGENITOR CELL; MOUSE; NONHUMAN; PRECURSOR; PRIORITY JOURNAL; RNA SEQUENCE; SINGLE CELL ANALYSIS; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL DIFFERENTIATION; CELL SEPARATION; CYTOLOGY; DEFICIENCY; DISEASE MODEL; GENETICS; HUMAN; IMMUNOLOGY; IMMUNOTHERAPY; INNATE IMMUNITY; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; METABOLISM; NATURAL KILLER CELL; NUCLEOTIDE SEQUENCE; PNEUMONIA; T LYMPHOCYTE; TRENDS;

MUS;

ANIMALS; ANTIBODIES; BASE SEQUENCE; CELL DIFFERENTIATION; CELL LINEAGE; CELL SEPARATION; CYTOKINES; DISEASE MODELS, ANIMAL; HUMANS; IMMUNITY, INNATE; IMMUNOTHERAPY; INFLUENZA, HUMAN; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; LYMPHOID PROGENITOR CELLS; MICE; MICE, INBRED C57BL; PNEUMONIA; PROGRAMMED CELL DEATH 1 RECEPTOR; RECEPTORS, INTERLEUKIN; REPRESSOR PROTEINS; SINGLE-CELL ANALYSIS; T-LYMPHOCYTES; TUMOR SUPPRESSOR PROTEINS;

EID: 84994551721     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature20105     Document Type: Article

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