DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk

International Journal of Cancer

Volumn 140, Issue 1, 2017, Pages 50-61

  Baglietto, Laura ^a,b,c,d   Ponzi, Erica ^e   Haycock, Philip ^f   Hodge, Allison ^d   Bianca Assumma, Manuela ^g   Jung, Chol Hee ^h   Chung, Jessica ^h   Fasanelli, Francesca ^g,i   Guida, Florence ^j   Campanella, Gianluca ^j   Chadeau Hyam, Marc ^j   Grankvist, Kjell ^k   Johansson, Mikael ^k   Ala, Ugo ^l   Provero, Paolo ^l,m   Wong, Ee Ming ^h   Joo, Jihoon ^h   English, Dallas R ^c,d   Kazmi, Nabila ^f   Lund, Eiliv ⁿ   Faltus, Christian ^o,p   Kaaks, Rudolf ^p,q   Risch, Angela ^o,p,q   Barrdahl, Myrto ^p   Sandanger, Torkjel M ⁿ   Southey, Melissa C ^h   Giles, Graham G ^c,d   Johansson, Mattias ^r   Vineis, Paolo ^g,j   Polidoro, Silvia ^g   Relton, Caroline L ^f   Severi, Gianluca ^a,b,c,d,g   more..

^a LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c CANCER EPIDEMIOLOGY CENTRE   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e UNIVERSITY OF ZURICH   (Switzerland)

^f UNIVERSITY OF BRISTOL   (United Kingdom)

^g Human Genetics Foundation   (Italy)

^h UNIVERSITY OF MELBOURNE   (Australia)

ⁱ CITTÀ DELLA SALUTE E DELLA SCIENZA HOSPITAL   (Italy)

^j IMPERIAL COLLEGE LONDON   (United Kingdom)

^k UMEÅ UNIVERSITY   (Sweden)

^l UNIVERSITY OF TURIN   (Italy)

^m SAN RAFFAELE HOSPITAL   (Italy)

ⁿ UNIVERSITY OF TROMSØ   (Norway)

^o UNIVERSITY OF SALZBURG   (Austria)

^p GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^q MEMBER OF THE GERMAN CENTER FOR LUNG RESEARCH DZL   (Germany)

^r INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

more..

Author keywords

DNA methylation; lung cancer risk; smoking

Indexed keywords

DNA;

ARTICLE; BLOOD SAMPLING; CANCER RISK; CASE CONTROL STUDY; COHORT ANALYSIS; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETICS; GENETIC ASSOCIATION; GENETIC RISK; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MEDICAL HISTORY; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SMOKING; SMOKING CESSATION; VALIDATION STUDY; ADVERSE EFFECTS; BLOOD; CHEMICALLY INDUCED; EARLY CANCER DIAGNOSIS; FEMALE; GENETIC EPIGENESIS; GENETIC PREDISPOSITION; GENETICS; LUNG NEOPLASMS; MALE; MICROARRAY ANALYSIS; PROCEDURES;

CASE-CONTROL STUDIES; DNA; DNA METHYLATION; EARLY DETECTION OF CANCER; EPIGENESIS, GENETIC; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUNG NEOPLASMS; MALE; MICROARRAY ANALYSIS; SMOKING;

EID: 84994465426     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.30431     Document Type: Article

References (29)

1. Parkin DM. Tobacco-attributable cancer burden in the UK in 2010. Br J Cancer 2011;105 (Suppl 2):S6–S13.
2. Simonato L, Agudo A, Ahrens W, et al. Lung cancer and cigarette smoking in Europe: an update of risk estimates and an assessment of inter-country heterogeneity. Int J Cancer 2001;91:876–87.
3. Services UDoHaH. US Department of Health and Human Services: The biology… - Google Scholared.: National Center for Chronic …, 2010.
4. Harlid S, Xu Z, Panduri V, et al. CpG sites associated with cigarette smoking: analysis of epigenome-wide data from the Sister Study. Environ Health Perspect 2014;122:673–8.
5. Dogan MV, Shields B, Cutrona C, et al. The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American women. BMC Genom 2014;15:151
6. Elliott HR, Tillin T, McArdle WL, et al. Differences in smoking associated DNA methylation patterns in South Asians and Europeans. Clin Epigenet 2014;6:4
7. Shenker NS, Ueland PM, Polidoro S, et al. DNA methylation as a long-term biomarker of exposure to tobacco smoke. Epidemiology 2013;24:712–16.
8. Sun YV, Smith AK, Conneely KN, et al. Epigenomic association analysis identifies smoking-related DNA methylation sites in African Americans. Hum Genet 2013;132:1027–37.
9. Shenker NS, Polidoro S, van Veldhoven K, et al. Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking. Hum Mol Genet 2013;22:843–51.
10. Besingi W, Johansson A. Smoke-related DNA methylation changes in the etiology of human disease. Hum Mol Genet 2014;23:2290–7.
11. Breitling LP, Yang R, Korn B, et al. Tobacco-smoking-related differential DNA methylation: 27K discovery and replication. Am J Hum Genet 2011;88:450–7.
12. Guida F, Sandanger TM, Castagne R, et al. Dynamics of smoking-induced genome-wide methylation changes with time since smoking cessation. Hum Mol Genet 2015;24:2349–59.
13. Fasanelli F, Baglietto L, Ponzi E, et al. Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts. Nat Commun 2015;6:10192.
14. Zhang Y, Schöttker B, Ordóñez-Mena J, et al. F2RL3 methylation, lung cancer incidence and mortality. Int J Cancer 2015;137:1739–48.
15. Riboli E, Kaaks R. The EPIC Project: rationale and study design. European Prospective Investigation into Cancer and Nutrition. Int J Epidemiol 1997;26 Suppl 1:S6–14.
16. Palli D, Berrino F, Vineis P, et al. A molecular epidemiology project on diet and cancer: the EPIC-Italy Prospective Study. Design and baseline characteristics of participants. Tumori 2003;89:586–93.
17. Giles GG, English DR. The Melbourne Collaborative Cohort Study. IARC Sci Publ 2002;156:69–70.
18. Hallmans G, Agren A, Johansson G, et al. Cardiovascular disease and diabetes in the Northern Sweden Health and Disease Study Cohort—evaluation of risk factors and their interactions. Scand J Public Health Suppl 2003;61:18–24.
19. Boeing H, Wahrendorf J, Becker N. EPIC-Germany–A source for studies into diet and risk of chronic diseases. European Investigation into Cancer and Nutrition. Annals of Nutrition & Metabolism 1999;43:195–204.
20. Joo JE, Wong EM, Baglietto L, et al. The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array. BMC Biotechnology 2013;13:23
21. Du P, Zhang X, Huang CC, et al. Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis. BMC Bioinformatics 2010;11:587
22. Houseman EA, Accomando WP, Koestler DC, et al. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics 2012;13:86
23. Salpea P, Russanova VR, Hirai TH, et al. Postnatal development- and age-related changes in DNA-methylation patterns in the human genome. Nucleic Acids Res 2012;40:6477–94.
24. Koshida K, Stigbrand T, Munck-Wikland E, et al. Analysis of serum placental alkaline phosphatase activity in testicular cancer and cigarette smokers. Urol Res 1990;18:169–73.
25. Li H, Wang RM, Liu SG, et al. Abnormal expression of FLOT1 correlates with tumor progression and poor survival in patients with non-small cell lung cancer. Tumour Biol 2014;35:3311–15.
26. Wikman H, Nymark P, Vayrynen A, et al. CDK4 is a probable target gene in a novel amplicon at 12q13.3-q14.1 in lung cancer. Gene Chromosomes Cancer 2005;42:193–9.
27. Relton CL, Hartwig FP, Davey Smith G. From stem cells to the law courts: DNA methylation, the forensic epigenome and the possibility of a biosocial archive. Int J Epidemiol 2015;44:1083–93.
28. Wiencke JK, Butler R, et al. The dna methylation profile of activated human natural killer cells. Epigenetics 2016;11:363–80.
29. Kolahian S, Oz HH, Zhou B, et al. The emerging role of myeloid-derived suppressor cells in lung diseases. Eur Respir J 2016;47:967–77.