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Volumn 7, Issue 5, 2016, Pages

Broadly neutralizing hemagglutinin stalk-specific antibodies induce potent phagocytosis of immune complexes by neutrophils in an Fc-dependent manner

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; HEMAGGLUTININ; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; NEUTRALIZING ANTIBODY; REACTIVE OXYGEN METABOLITE; ANTIGEN ANTIBODY COMPLEX; INFLUENZA VIRUS HEMAGGLUTININ; MONOCLONAL ANTIBODY; VIRUS ANTIBODY;

EID: 84994423081     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01624-16     Document Type: Article
Times cited : (98)

References (52)
  • 1
    • 84924060844 scopus 로고    scopus 로고
    • Advances in the development of influenza virus vaccines
    • Krammer F, Palese P. 2015. Advances in the development of influenza virus vaccines. Nat Rev Drug Discov 14:167-182. http://dx.doi.org/10.1038/nrd4529
    • (2015) Nat Rev Drug Discov , vol.14 , pp. 167-182
    • Krammer, F.1    Palese, P.2
  • 2
    • 84885953445 scopus 로고    scopus 로고
    • Influenza virus hemagglutinin stalk-based antibodies and vaccines
    • Krammer F, Palese P. 2013. Influenza virus hemagglutinin stalk-based antibodies and vaccines. Curr Opin Virol 3:521-530. http://dx.doi.org/10.1016/j.coviro.2013.07.007
    • (2013) Curr Opin Virol , vol.3 , pp. 521-530
    • Krammer, F.1    Palese, P.2
  • 3
    • 84893496184 scopus 로고    scopus 로고
    • H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge
    • Krammer F, Margine I, Hai R, Flood A, Hirsh A, Tsvetnitsky V, Chen D, Palese P. 2014. H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge. J Virol 88:2340-2343. http://dx.doi.org/10.1128/JVI.03183-13
    • (2014) J Virol , vol.88 , pp. 2340-2343
    • Krammer, F.1    Margine, I.2    Hai, R.3    Flood, A.4    Hirsh, A.5    Tsvetnitsky, V.6    Chen, D.7    Palese, P.8
  • 4
    • 84878611784 scopus 로고    scopus 로고
    • Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalkspecific antibodies
    • Krammer F, Pica N, Hai R, Margine I, Palese P. 2013. Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalkspecific antibodies. J Virol 87:6542-6550. http://dx.doi.org/10.1128/JVI.00641-13
    • (2013) J Virol , vol.87 , pp. 6542-6550
    • Krammer, F.1    Pica, N.2    Hai, R.3    Margine, I.4    Palese, P.5
  • 7
    • 84931573106 scopus 로고    scopus 로고
    • Vaccination with soluble headless hemagglutinin protects mice from challenge with divergent influenza viruses
    • Wohlbold TJ, Nachbagauer R, Margine I, Tan GS, Hirsh A, Krammer F. 2015. Vaccination with soluble headless hemagglutinin protects mice from challenge with divergent influenza viruses. Vaccine 33:3314-3321. http://dx.doi.org/10.1016/j.vaccine.2015.05.038
    • (2015) Vaccine , vol.33 , pp. 3314-3321
    • Wohlbold, T.J.1    Nachbagauer, R.2    Margine, I.3    Tan, G.S.4    Hirsh, A.5    Krammer, F.6
  • 8
    • 84872924387 scopus 로고    scopus 로고
    • 1976 and 2009 H1N1 influenza virus vaccines boost antihemagglutinin stalk antibodies in humans
    • Miller MS, Tsibane T, Krammer F, Hai R, Rahmat S, Basler CF, Palese P. 2013. 1976 and 2009 H1N1 influenza virus vaccines boost antihemagglutinin stalk antibodies in humans. J Infect Dis 207:98-105. http://dx.doi.org/10.1093/infdis/jis652
    • (2013) J Infect Dis , vol.207 , pp. 98-105
    • Miller, M.S.1    Tsibane, T.2    Krammer, F.3    Hai, R.4    Rahmat, S.5    Basler, C.F.6    Palese, P.7
  • 10
    • 84883856356 scopus 로고    scopus 로고
    • Neutralizing antibodies against previously encountered influenza virus strains increase over time: A longitudinal analysis
    • 198ra107
    • Miller MS, Gardner TJ, Krammer F, Aguado LC, Tortorella D, Basler CF, Palese P. 2013. Neutralizing antibodies against previously encountered influenza virus strains increase over time: a longitudinal analysis. Sci Transl Med 5:198ra107. http://dx.doi.org/10.1126/scitranslmed.3006637
    • (2013) Sci Transl Med , vol.5
    • Miller, M.S.1    Gardner, T.J.2    Krammer, F.3    Aguado, L.C.4    Tortorella, D.5    Basler, C.F.6    Palese, P.7
  • 15
    • 84908389429 scopus 로고    scopus 로고
    • Induction of broadly reactive anti-hemagglutinin stalk antibodies by an H5N1 vaccine in humans
    • Nachbagauer R, Wohlbold TJ, Hirsh A, Hai R, Sjursen H, Palese P, Cox RJ, Krammer F. 2014. Induction of broadly reactive anti-hemagglutinin stalk antibodies by an H5N1 vaccine in humans. J Virol 88:13260-13268. http://dx.doi.org/10.1128/JVI.02133-14
    • (2014) J Virol , vol.88 , pp. 13260-13268
    • Nachbagauer, R.1    Wohlbold, T.J.2    Hirsh, A.3    Hai, R.4    Sjursen, H.5    Palese, P.6    Cox, R.J.7    Krammer, F.8
  • 17
    • 84893797938 scopus 로고    scopus 로고
    • Broadly neutralizing hemagglutinin stalk-specific antibodies require Fc÷R interactions for protection against influenza virus in vivo
    • DiLillo DJ, Tan GS, Palese P, Ravetch JV. 2014. Broadly neutralizing hemagglutinin stalk-specific antibodies require Fc÷R interactions for protection against influenza virus in vivo. Nat Med 20:143-151. http://dx.doi.org/10.1038/nm.3443
    • (2014) Nat Med , vol.20 , pp. 143-151
    • Dilillo, D.J.1    Tan, G.S.2    Palese, P.3    Ravetch, J.V.4
  • 19
    • 0035877057 scopus 로고    scopus 로고
    • Fc receptormediated phagocytosis makes a significant contribution to clearance of influenza virus infections
    • Huber VC, Lynch JM, Bucher DJ, Le J, Metzger DW. 2001. Fc receptormediated phagocytosis makes a significant contribution to clearance of influenza virus infections. J Immunol 166:7381-7388. http://dx.doi.org/10.4049/jimmunol.166.12.7381
    • (2001) J Immunol , vol.166 , pp. 7381-7388
    • Huber, V.C.1    Lynch, J.M.2    Bucher, D.J.3    Le, J.4    Metzger, D.W.5
  • 20
    • 84880676381 scopus 로고    scopus 로고
    • Diverse novel functions of neutrophils in immunity, inflammation, and beyond
    • Mócsai A. 2013. Diverse novel functions of neutrophils in immunity, inflammation, and beyond. J Exp Med 210:1283-1299. http://dx.doi.org/10.1084/jem.20122220
    • (2013) J Exp Med , vol.210 , pp. 1283-1299
    • Mócsai, A.1
  • 22
    • 34447525439 scopus 로고    scopus 로고
    • Beneficial suicide: Why neutrophils die to make NETs
    • Brinkmann V, Zychlinsky A. 2007. Beneficial suicide: why neutrophils die to make NETs. Nat Rev Microbiol 5:577-582. http://dx.doi.org/10.1038/nrmicro1710
    • (2007) Nat Rev Microbiol , vol.5 , pp. 577-582
    • Brinkmann, V.1    Zychlinsky, A.2
  • 23
    • 52649136695 scopus 로고    scopus 로고
    • The role of neutrophils in the upper and lower respiratory tract during influenza virus infection of mice
    • Tate MD, Brooks AG, Reading PC. 2008. The role of neutrophils in the upper and lower respiratory tract during influenza virus infection of mice. Respir Res 9:57. http://dx.doi.org/10.1186/1465-9921-9-57
    • (2008) Respir Res , vol.9
    • Tate, M.D.1    Brooks, A.G.2    Reading, P.C.3
  • 24
    • 79952634012 scopus 로고    scopus 로고
    • The role of neutrophils during mild and severe influenza virus in-fections of mice
    • Tate MD, Ioannidis LJ, Croker B, Brown LE, Brooks AG, Reading PC. 2011. The role of neutrophils during mild and severe influenza virus in-fections of mice. PLoS One 6:e17618. http://dx.doi.org/10.1371/journal.pone.0017618
    • (2011) Plos One , vol.6
    • Tate, M.D.1    Ioannidis, L.J.2    Croker, B.3    Brown, L.E.4    Brooks, A.G.5    Reading, P.C.6
  • 25
    • 84961938333 scopus 로고    scopus 로고
    • Fc-receptor interactions regulate both cytotoxic and immunomodulatory therapeutic antibody effector functions
    • DiLillo DJ, Ravetch JV. 2015. Fc-receptor interactions regulate both cytotoxic and immunomodulatory therapeutic antibody effector functions. Cancer Immunol Res 3:704-713. http://dx.doi.org/10.1158/2326-6066.CIR-15-0120
    • (2015) Cancer Immunol Res , vol.3 , pp. 704-713
    • Dilillo, D.J.1    Ravetch, J.V.2
  • 26
    • 22544487815 scopus 로고    scopus 로고
    • FcgammaRIV: A novel FcR with distinct IgG subclass specificity
    • Nimmerjahn F, Bruhns P, Horiuchi K, Ravetch JV. 2005. FcgammaRIV: a novel FcR with distinct IgG subclass specificity. Immunity 23:41-51
    • (2005) Immunity , vol.23 , pp. 41-51
    • Nimmerjahn, F.1    Bruhns, P.2    Horiuchi, K.3    Ravetch, J.V.4
  • 27
    • 65549114676 scopus 로고    scopus 로고
    • Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses
    • Bruhns P, Iannascoli B, England P, Mancardi DA, Fernandez N, Jorieux S, Daëron M. 2009. Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses. Blood 113: 3716-3725. http://dx.doi.org/10.1182/blood-2008-09-179754
    • (2009) Blood , vol.113 , pp. 3716-3725
    • Bruhns, P.1    Iannascoli, B.2    England, P.3    Mancardi, D.A.4    Fernandez, N.5    Jorieux, S.6    Daëron, M.7
  • 28
    • 0029863313 scopus 로고    scopus 로고
    • Isoluminol-enhanced chemiluminescence: A sensitive method to study the release of superoxide anion from human neutrophils
    • Lundqvist H, Dahlgren C. 1996. Isoluminol-enhanced chemiluminescence: a sensitive method to study the release of superoxide anion from human neutrophils. Free Radic Biol Med 20:785-792. http://dx.doi.org/10.1016/0891-5849(95)02189-2
    • (1996) Free Radic Biol Med , vol.20 , pp. 785-792
    • Lundqvist, H.1    Dahlgren, C.2
  • 29
    • 84863597077 scopus 로고    scopus 로고
    • A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo
    • Tan GS, Krammer F, Eggink D, Kongchanagul A, Moran TM, Palese P. 2012. A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo. J Virol 86:6179-6188. http://dx.doi.org/10.1128/JVI.00469-12
    • (2012) J Virol , vol.86 , pp. 6179-6188
    • Tan, G.S.1    Krammer, F.2    Eggink, D.3    Kongchanagul, A.4    Moran, T.M.5    Palese, P.6
  • 30
    • 84880617786 scopus 로고    scopus 로고
    • In vivo bioluminescent imaging of influenza A virus infection and char
    • Heaton NS, Leyva-Grado VH, Tan GS, Eggink D, Hai R, Palese P. 2013. In vivo bioluminescent imaging of influenza A virus infection and characterization of novel cross-protective monoclonal antibodies. J Virol 87: 8272-8281. http://dx.doi.org/10.1128/JVI.00969-13
    • (2013) J Virol , vol.87 , pp. 8272-8281
    • Heaton, N.S.1    Leyva-Grado, V.H.2    Tan, G.S.3    Eggink, D.4    Hai, R.5    Palese, P.6
  • 31
    • 84861325359 scopus 로고    scopus 로고
    • Influenza viruses expressing chimeric hemagglutinins: Globular head and stalk domains derived from different subtypes
    • Hai R, Krammer F, Tan GS, Pica N, Eggink D, Maamary J, Margine I, Albrecht RA, Palese P. 2012. Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes. J Virol 86:5774-5781. http://dx.doi.org/10.1128/JVI.00137-12
    • (2012) J Virol , vol.86 , pp. 5774-5781
    • Hai, R.1    Krammer, F.2    Tan, G.S.3    Pica, N.4    Eggink, D.5    Maamary, J.6    Margine, I.7    Albrecht, R.A.8    Palese, P.9
  • 34
    • 84911434712 scopus 로고    scopus 로고
    • Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin
    • Tan GS, Lee PS, Hoffman RMB, Mazel-Sanchez B, Krammer F, Leon PE, Ward AB, Wilson IA, Palese P. 2014. Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin. J Virol 88:13580-13592. http://dx.doi.org/10.1128/JVI.02289-14
    • (2014) J Virol , vol.88 , pp. 13580-13592
    • Tan, G.S.1    Lee, P.S.2    Hoffman, R.3    Mazel-Sanchez, B.4    Krammer, F.5    Leon, P.E.6    Ward, A.B.7    Wilson, I.A.8    Palese, P.9
  • 35
    • 0023612465 scopus 로고
    • Characterization of variable-region genes and shared crossreactive idiotypes of antibodies spe-cific for antigens of various influenza viruses
    • Moran TM, Monestier M, Lai AC, Norton G, Reale MA, Thompson MA, Schulman JL, Riblet R, Bona CA. 1987. Characterization of variable-region genes and shared crossreactive idiotypes of antibodies spe-cific for antigens of various influenza viruses. Viral Immunol 1:1-12. http://dx.doi.org/10.1089/vim.1987.1.1
    • (1987) Viral Immunol , vol.1 , pp. 1-12
    • Moran, T.M.1    Monestier, M.2    Lai, A.C.3    Norton, G.4    Reale, M.A.5    Thompson, M.A.6    Schulman, J.L.7    Riblet, R.8    Bona, C.A.9
  • 36
    • 84924777947 scopus 로고    scopus 로고
    • Broadly neutralizing anti-influenza virus antibodies: Enhancement of neutralizing potency in polyclonal mixtures and IgA backbones
    • He W, Mullarkey CE, Duty JA, Moran TM, Palese P, Miller MS. 2015. Broadly neutralizing anti-influenza virus antibodies: enhancement of neutralizing potency in polyclonal mixtures and IgA backbones. J Virol 89:3610-3618. http://dx.doi.org/10.1128/JVI.03099-14
    • (2015) J Virol , vol.89 , pp. 3610-3618
    • He, W.1    Mullarkey, C.E.2    Duty, J.A.3    Moran, T.M.4    Palese, P.5    Miller, M.S.6
  • 37
    • 0344643399 scopus 로고    scopus 로고
    • Unique monoclonal antibodies define expression of Fc RI on macrophages and mast cell lines and demonstrate heterogeneity among subcutaneous and other dendritic cells
    • Tan PS, Gavin AL, Barnes N, Sears DW, Vremec D, Shortman K, Amigorena S, Mottram PL, Hogarth PM. 2003. Unique monoclonal antibodies define expression of Fc RI on macrophages and mast cell lines and demonstrate heterogeneity among subcutaneous and other dendritic cells. J Immunol 170:2549-2556. http://dx.doi.org/10.4049/jimmunol.170.5.2549
    • (2003) J Immunol , vol.170 , pp. 2549-2556
    • Tan, P.S.1    Gavin, A.L.2    Barnes, N.3    Sears, D.W.4    Vremec, D.5    Shortman, K.6    Amigorena, S.7    Mottram, P.L.8    Hogarth, P.M.9
  • 39
    • 84945264927 scopus 로고    scopus 로고
    • The era of the immunoglobulin A Fc receptor FcγRI; its function and potential as target in disease
    • Aleyd E, Heineke MH, van Egmond M. 2015. The era of the immunoglobulin A Fc receptor FcγRI; its function and potential as target in disease. Immunol Rev 268:123-138. http://dx.doi.org/10.1111/imr.12337
    • (2015) Immunol Rev , vol.268 , pp. 123-138
    • Aleyd, E.1    Heineke, M.H.2    Van Egmond, M.3
  • 41
  • 45
    • 84956934982 scopus 로고    scopus 로고
    • Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection
    • DiLillo DJ, Palese P, Wilson PC, Ravetch JV. 2016. Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection. J Clin Invest 126:605-610. http://dx.doi.org/10.1172/JCI84428
    • (2016) J Clin Invest , vol.126 , pp. 605-610
    • Dilillo, D.J.1    Palese, P.2    Wilson, P.C.3    Ravetch, J.V.4
  • 48
    • 84920274731 scopus 로고    scopus 로고
    • The role of HIV-specific antibody-dependent cellular cytotoxicity in HIV prevention and the influence of the HIV-1 Vpu protein
    • Kramski M, Stratov I, Kent SJ. 2015. The role of HIV-specific antibody-dependent cellular cytotoxicity in HIV prevention and the influence of the HIV-1 Vpu protein. AIDS 29:137-144. http://dx.doi.org/10.1097/QAD.0000000000000523
    • (2015) AIDS , vol.29 , pp. 137-144
    • Kramski, M.1    Stratov, I.2    Kent, S.J.3
  • 49
    • 84930081913 scopus 로고    scopus 로고
    • Differential Fc-receptor engagement drives an anti-tumor vaccinal effect
    • DiLillo DJ, Ravetch JV. 2015. Differential Fc-receptor engagement drives an anti-tumor vaccinal effect. Cell 161:1035-1045. http://dx.doi.org/10.1016/j.cell.2015.04.016
    • (2015) Cell , vol.161 , pp. 1035-1045
    • Dilillo, D.J.1    Ravetch, J.V.2
  • 50
    • 48549100414 scopus 로고    scopus 로고
    • Immunotherapeutic mechanisms of anti-CD20 monoclonal antibodies
    • Taylor RP, Lindorfer MA. 2008. Immunotherapeutic mechanisms of anti-CD20 monoclonal antibodies. Curr Opin Immunol 20:444-449. http://dx.doi.org/10.1016/j.coi.2008.05.011
    • (2008) Curr Opin Immunol , vol.20 , pp. 444-449
    • Taylor, R.P.1    Lindorfer, M.A.2
  • 51
    • 3042592452 scopus 로고    scopus 로고
    • The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy
    • Uchida J, Hamaguchi Y, Oliver JA, Ravetch JV, Poe JC, Haas KM, Tedder TF. 2004. The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J Exp Med 199:1659-1669. http://dx.doi.org/10.1084/jem.20040119
    • (2004) J Exp Med , vol.199 , pp. 1659-1669
    • Uchida, J.1    Hamaguchi, Y.2    Oliver, J.A.3    Ravetch, J.V.4    Poe, J.C.5    Haas, K.M.6    Tedder, T.F.7
  • 52
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets
    • Clynes RA, Towers TL, Presta LG, Ravetch JV. 2000. Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets. Nat Med 6:443-446. http://dx.doi.org/10.1038/74704
    • (2000) Nat Med , vol.6 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4


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