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Volumn 20, Issue 4, 2008, Pages 444-449

Immunotherapeutic mechanisms of anti-CD20 monoclonal antibodies

Author keywords

[No Author keywords available]

Indexed keywords

CD16 ANTIGEN; CD19 ANTIGEN; CD20 ANTIBODY; CD20 ANTIGEN; FC RECEPTOR; FRESH FROZEN PLASMA; IMMUNOGLOBULIN G1 ANTIBODY; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; OFATUMUMAB; RITUXIMAB;

EID: 48549100414     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coi.2008.05.011     Document Type: Review
Times cited : (133)

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    • DiLillo D.J., Hamaguchi Y., Ueda Y., Yang K., Uchida J., Haas K.M., Kelsoe G., and Tedder T.F. Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice. J Immunol 180 (2008) 361-371. This definitive mouse model paper shows that anti-CD20 therapy has little, if any effect on the levels of existing antibodies in mice because long-lived plasma cells are not depleted by anti-CD20 mAbs. The paper has important implications for our understanding of how RTX may function in the therapy of autoimmune diseases, and why individuals who receive RTX therapy are generally not at increased risk for infections.
    • (2008) J Immunol , vol.180 , pp. 361-371
    • DiLillo, D.J.1    Hamaguchi, Y.2    Ueda, Y.3    Yang, K.4    Uchida, J.5    Haas, K.M.6    Kelsoe, G.7    Tedder, T.F.8
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    • B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity
    • Yanaba K., Hamaguchi Y., Venturi G.M., Steeber D.A., St. Clair E.W., and Tedder T.F. B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity. J Immunol 179 (2007) 1369-1380
    • (2007) J Immunol , vol.179 , pp. 1369-1380
    • Yanaba, K.1    Hamaguchi, Y.2    Venturi, G.M.3    Steeber, D.A.4    St. Clair, E.W.5    Tedder, T.F.6
  • 55
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    • Depletion of B cells in murine lupus: efficacy and resistance
    • ••], have important implications with respect to understanding the efficacy of B cell depletion therapies in human SLE.
    • ••], have important implications with respect to understanding the efficacy of B cell depletion therapies in human SLE.
    • (2007) J Immunol , vol.179 , pp. 3351-3361
    • Ahuja, A.1    Shupe, J.2    Dunn, R.3    Kashgarian, M.4    Kehry, M.R.5    Shlomchik, M.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.