Heterogeneity, functional specialization and differentiation of monocyte-derived dendritic cells

Immunology and Cell Biology

Volumn 95, Issue 3, 2017, Pages 244-251

  Chow, Kevin V ^a,b,c   Sutherland, Robyn M ^a,b   Zhan, Yifan ^a,b   Lew, Andrew M ^a,b,d  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b Department of Medical Biology ^*  (Australia)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL FUNCTION; CELL HETEROGENEITY; CELL POPULATION; CELL SPECIFICITY; DENDRITIC CELL; EFFECTOR CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFECTION; INFLAMMATION; INNATE IMMUNITY; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MONOCYTE; NONHUMAN; REVIEW; ANIMAL; CYTOLOGY; DISEASES; IMMUNITY;

ANIMALS; CELL DIFFERENTIATION; DENDRITIC CELLS; DISEASE; HUMANS; IMMUNITY; MONOCYTES;

EID: 84994423062     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2016.104     Document Type: Review

References (60)

1. Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J ExpMed 1994; 179: 1109-1118.
2. Randolph GJ, Inaba K, Robbiani DF, Steinman RM, Muller WA. Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity 1999; 11: 753-761.
3. Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol 2005; 5: 953-964.
4. Auffray C, Fogg D, Garfa M, Elain G, Join-Lambert O, Kayal S et al. Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science 2007; 317: 666-670.
5. Auffray C, Sieweke MH, Geissmann F. Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu Rev Immunol 2009; 27: 669-692.
6. Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 2003; 19: 71-82.
7. Serbina NV, Pamer EG. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol 2006; 7: 311-317.
8. Serbina NV, Salazar-Mather TP, Biron CA, Kuziel WA, Pamer EG. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 2003; 19: 59-70.
9. Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL et al. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med 2007; 204: 3037-3047.
10. Arnold L, Henry A, Poron F, Baba-Amer Y, van Rooijen N, Plonquet A et al. Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. J Exp Med 2007; 204: 1057-1069.
11. Hanna RN, Cekic C, Sag D, Tacke R, Thomas GD, Nowyhed H et al. Patrolling monocytes control tumor metastasis to the lung. Science 2015; 350: 985-990.
12. Wong KL, Yeap WH, Tai JJ, Ong SM, Dang TM, Wong SC. The three human monocyte subsets: implications for health and disease. Immunol Res 2012; 53: 41-57.
13. Sunderkotter C, Nikolic T, Dillon MJ, Van Rooijen N, Stehling M, Drevets DA et al. Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol 2004; 172: 4410-4417.
14. Yona S, Kim KW, Wolf Y, Mildner A, Varol D, Breker M et al. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity 2013; 38: 79-91.
15. Czuprynski CJ, Brown JF, Maroushek N, Wagner RD, Steinberg H. Administration of anti-granulocyte mAb RB6-8C5 impairs the resistance of mice to Listeria monocytogenes infection. J Immunol 1994; 152: 1836-1846.
16. Rosen H, Gordon S, North RJ. Exacerbation of murine listeriosis by a monoclonal antibody specific for the type 3 complement receptor of myelomonocytic cells. Absence of monocytes at infective foci allows Listeria to multiply in nonphagocytic cells. J Exp Med 1989; 170: 27-37.
17. Peters W, Cyster JG, Mack M, Schlondorff D, Wolf AJ, Ernst JD et al. CCR2-dependent trafficking of F4/80dim macrophages and CD11cdim/intermediate dendritic cells is crucial for T cell recruitment to lungs infected with Mycobacterium tuberculosis. J Immunol 2004; 172: 7647-7653.
18. Robben PM, LaRegina M, Kuziel WA, Sibley LD. Recruitment of Gr-1+ monocytes is essential for control of acute toxoplasmosis. J Exp Med 2005; 201: 1761-1769.
19. Ginhoux F, Jung S. Monocytes and macrophages: developmental pathways and tissue homeostasis. Nat Rev Immunol 2014; 14: 392-404.
20. Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, Leboeuf M et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity 2013; 38: 792-804.
21. Tamoutounour S, Guilliams M, Montanana Sanchis F, Liu H, Terhorst D, Malosse C et al. Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skin. Immunity 2013; 39: 925-938.
22. Epelman S, Lavine KJ, Beaudin AE, Sojka DK, Carrero JA, Calderon B et al. Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. Immunity 2014; 40: 91-104.
23. Leon B, Martinez del Hoyo G, Parrillas V, Vargas HH, Sanchez-Mateos P, Longo N et al. Dendritic cell differentiation potential of mouse monocytes: monocytes represent immediate precursors of CD8-and CD8+ splenic dendritic cells. Blood 2004; 103: 2668-2676.
24. Leon B, Lopez-Bravo M, Ardavin C. Monocyte-derived dendritic cells. Semin Immunol 2005; 17: 313-318.
25. Palucka KA, Taquet N, Sanchez-Chapuis F, Gluckman JC. Lipopolysaccharide can block the potential of monocytes to differentiate into dendritic cells. J Leukoc Biol 1999; 65: 232-240.
26. Mohamadzadeh M, Berard F, Essert G, Chalouni C, Pulendran B, Davoust J et al. Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells. J Exp Med 2001; 194: 1013-1020.
27. Santini SM, Lapenta C, Logozzi M, Parlato S, Spada M, Di Pucchio T et al. Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice. J Exp Med 2000; 191: 1777-1788.
28. Raker VK, Domogalla MP, Steinbrink K. Tolerogenic dendritic cells for regulatory T cell induction in man. Front Immunol 2015; 6: 569.
29. Ezzelarab MB, Zahorchak AF, Lu L, Morelli AE, Chalasani G, Demetris AJ et al. Regulatory dendritic cell infusion prolongs kidney allograft survival in nonhuman primates. Am J Transplant 2013; 13: 1989-2005.
30. Rotta G, Edwards EW, Sangaletti S, Bennett C, Ronzoni S, Colombo MP et al. Lipopolysaccharide or whole bacteria block the conversion of inflammatory monocytes into dendritic cells in vivo. J Exp Med 2003; 198: 1253-1263.
31. Qu C, Edwards EW, Tacke F, Angeli V, Llodra J, Sanchez-Schmitz G et al. Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes. J Exp Med 2004; 200: 1231-1241.
32. Helft J, Bottcher J, Chakravarty P, Zelenay S, Huotari J, Schraml BU et al. GM-CSF mouse bone marrow cultures comprise a heterogeneous population of CD11c(+)MHCII(+) macrophages and dendritic cells. Immunity 2015; 42: 1197-1211.
33. Greter M, Helft J, Chow A, Hashimoto D, Mortha A, Agudo-Cantero J et al. GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells. Immunity 2012; 36: 1031-1046.
34. Chow KV, Lew AM, Sutherland RM, Zhan Y. Monocyte-derived dendritic cells promote Th polarization, whereas conventional dendritic cells promote Th proliferation. J Immunol 2016; 196: 624-636.
35. Leon B, Lopez-Bravo M, Ardavin C. Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania. Immunity 2007; 26: 519-531.
36. Cheong C, Matos I, Choi JH, Dandamudi DB, Shrestha E, Longhi MP et al. Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas. Cell 2010; 143: 416-429.
37. Meredith MM, Liu K, Darrasse-Jeze G, Kamphorst AO, Schreiber HA, Guermonprez P et al. Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage. J Exp Med 2012; 209: 1153-1165.
38. Iijima N, Mattei LM, Iwasaki A. Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue. Proc Natl Acad Sci USA 2011; 108: 284-289.
39. Rydstrom A, Wick MJ. Monocyte recruitment, activation, and function in the gutassociated lymphoid tissue during oral Salmonella infection. J Immunol 2007; 178: 5789-5801.
40. Mayer-Barber KD, Andrade BB, Barber DL, Hieny S, Feng CG, Caspar P et al. Innate and adaptive interferons suppress IL-1alpha and IL-1beta production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection. Immunity 2011; 35: 1023-1034.
41. Osterholzer JJ, Curtis JL, Polak T, Ames T, Chen GH, McDonald R et al. CCR2 mediates conventional dendritic cell recruitment and the formation of bronchovascular mononuclear cell infiltrates in the lungs of mice infected with Cryptococcus neoformans. J Immunol 2008; 181: 610-620.
42. Hohl TM, Rivera A, Lipuma L, Gallegos A, Shi C, Mack M et al. Inflammatory monocytes facilitate adaptive CD4 T cell responses during respiratory fungal infection. Cell Host Microbe 2009; 6: 470-481.
43. Guilliams M, Movahedi K, Bosschaerts T, VandenDriessche T, Chuah MK, Herin M et al. IL-10 dampens TNF/inducible nitric oxide synthase-producing dendritic cell-mediated pathogenicity during parasitic infection. J Immunol 2009; 182: 1107-1118.
44. Ko HJ, Brady JL, Ryg-Cornejo V, Hansen DS, Vremec D, Shortman K et al. GM-CSF-responsive monocyte-derived dendritic cells are pivotal in Th17 pathogenesis. J Immunol 2014; 192: 2202-2209.
45. Campbell IK, van Nieuwenhuijze A, Segura E, O'Donnell K, Coghill E, Hommel M et al. Differentiation of inflammatory dendritic cells is mediated by NF-kappaB1-dependent GM-CSF production in CD4 T cells. J Immunol 2011; 186: 5468-5477.
46. Rivollier A, He J, Kole A, Valatas V, Kelsall BL. Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon. J Exp Med 2012; 209: 139-155.
47. Plantinga M, Guilliams M, Vanheerswynghels M, Deswarte K, Branco-Madeira F, Toussaint W et al. Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen. Immunity 2013; 38: 322-335.
48. Copin R, De Baetselier P, Carlier Y, Letesson JJ, Muraille E. MyD88-dependent activation of B220-CD11b+LY-6C+ dendritic cells during Brucella melitensis infection. J Immunol 2007; 178: 5182-5191.
49. Langlet C, Tamoutounour S, Henri S, Luche H, Ardouin L, Gregoire C et al. CD64 expression distinguishes monocyte-derived and conventional dendritic cells and reveals their distinct role during intramuscular immunization. J Immunol 2012; 188: 1751-1760.
50. Kool M, Soullie T, van Nimwegen M, Willart MA, Muskens F, Jung S et al. Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells. J Exp Med 2008; 205: 869-882.
51. Le Borgne M, Etchart N, Goubier A, Lira SA, Sirard JC, van Rooijen N et al. Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo. Immunity 2006; 24: 191-201.
52. Wakim LM, Waithman J, van Rooijen N, Heath WR, Carbone FR. Dendritic cell-induced memory T cell activation in nonlymphoid tissues. Science 2008; 319: 198-202.
53. Tezuka H, Abe Y, Iwata M, Takeuchi H, Ishikawa H, Matsushita M et al. Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells. Nature 2007; 448: 929-933.
54. Zecher D, van Rooijen N, Rothstein DM, Shlomchik WD, Lakkis FG. An innate response to allogeneic nonself mediated by monocytes. J Immunol 2009; 183: 7810-7816.
55. Oberbarnscheidt MH, Zeng Q, Li Q, Dai H, Williams AL, Shlomchik WD et al. Non-self recognition by monocytes initiates allograft rejection. J Clin Invest 2014; 124: 3579-3589.
56. Chow KV, Delconte RB, Huntington ND, Tarlinton DM, Sutherland RM, Zhan Y et al. Innate allorecognition results in rapid accumulation of monocyte-derived dendritic cells. J Immunol 2016; 197: 2000-2008.
57. Varol C, Landsman L, Fogg DK, Greenshtein L, Gildor B, Margalit R et al. Monocytes give rise to mucosal, but not splenic, conventional dendritic cells. J Exp Med 2007; 204: 171-180.
58. Landsman L, Varol C, Jung S. Distinct differentiation potential of blood monocyte subsets in the lung. J Immunol 2007; 178: 2000-2007.
59. Ginhoux F, Tacke F, Angeli V, Bogunovic M, Loubeau M, Dai XM et al. Langerhans cells arise from monocytes in vivo. Nat Immunol 2006; 7: 265-273.
60. Iijima N, Linehan MM, Saeland S, Iwasaki A. Vaginal epithelial dendritic cells renew from bone marrow precursors. Proc Natl Acad Sci USA 2007; 104: 19061-19066.