Monocyte-derived dendritic cells promote Th polarization, whereas conventional dendritic cells promote th proliferation

Journal of Immunology

Volumn 196, Issue 2, 2016, Pages 624-636

  Chow, Kevin V ^a,b,c   Lew, Andrew M ^a,b   Sutherland, Robyn M ^a,b   Zhan, Yifan ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NITRIC OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MONOCYTE; MONOCYTE DERIVED DENDRITIC CELL; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; T LYMPHOCYTE; TH1 CELL; TH17 CELL; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; COCULTURE; CYTOLOGY; FLOW CYTOMETRY; HELPER CELL; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE;

ANIMALS; ANTIGEN PRESENTATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; COCULTURE TECHNIQUES; DENDRITIC CELLS; FLOW CYTOMETRY; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; MONOCYTES; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84954101297     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1501202     Document Type: Article

References (66)

1. Shortman, K., and Y. J. Liu. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2: 151-161.
2. Kushwah, R., and J. Hu. 2011. Complexity of dendritic cell subsets and their function in the host immune system. Immunology 133: 409-419.
3. Siegal, F. P., N. Kadowaki, M. Shodell, P. A. Fitzgerald-Bocarsly, K. Shah, S. Ho, S. Antonenko, and Y. J. Liu. 1999. The nature of the principal type 1 interferon-producing cells in human blood. Science 284: 1835-1837.
4. Liu, Y. J. 2005. IPC: professional type 1 interferon-producing cells and plas-macytoid dendritic cell precursors. Annu. Rev. Immunol. 23: 275-306.
5. + dendritic cell subset. Immunol. Rev. 234: 18-31.
6. Heath, W. R., G. T. Belz, G. M. Behrens, C. M. Smith, S. P. Forehan, I. A. Parish, G. M. Davey, N. S. Wilson, F. R. Carbone, and J. A. Villadangos. 2004. Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunol. Rev. 199: 9-26.
7. Lewis, K. L., M. L. Caton, M. Bogunovic, M. Greter, L. T. Grajkowska, D. Ng, A. Klinakis, I. F. Charo, S. Jung, J. L. Gommerman, et al. 2011. Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. Immunity 35: 780-791.
8. Serbina, N. V., T. P. Salazar-Mather, C. A. Biron, W. A. Kuziel, and E. G. Pamer. 2003. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 19: 59-70.
9. León, B., M. López-Bravo, and C. Ardavin. 2007. Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania. Immunity 26: 519-531.
10. Chen, K., M. Liu, Y. Liu, C. Wang, T. Yoshimura, W. Gong, Y. Le, L. Tessarollo, and J. M. Wang. 2013. Signal relay by CC chemokine receptor 2 (CCR2) and formylpeptide receptor 2 (Fpr2) in the recruitment of monocyte-derived dendritic cells in allergic airway inflammation. J. Biol. Chem. 288: 16262-16273.
11. Nakano, H., K. L. Lin, M. Yanagita, C. Charbonneau, D. N. Cook, T. Kakiuchi, and M. D. Gunn. 2009. Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses. Nat. Immunol. 10: 394-402.
12. Zhan, Y., Y. Xu, S. Seah, J. L. Brady, E. M. Carrington, C. Cheers, B. A. Croker, L. Wu, J. A. Villadangos, and A. M. Lew. 2010. Resident and monocyte-derived dendritic cells become dominant IL-12 producers under different conditions and signaling pathways. J. Immunol. 185: 2125-2133.
13. + dendritic cells during Brucella melitensis infection. J. Immunol. 178: 5182-5191.
14. Guilliams, M., K. Movahedi, T. Bosschaerts, T. VandenDriessche, M. K. Chuah, M. Hérin, A. Acosta-Sanchez, L. Ma, M. Moser, J. A. Van Ginderachter, et al. 2009. IL-10 dampens TNF/inducible nitric oxide synthase-producing dendritic cell-mediated pathogenicity during parasitic infection. J. Immunol. 182: 1107-1118.
15. Rydström, A., and M. J. Wick. 2007. Monocyte recruitment, activation, and function in the gut-associated lymphoid tissue during oral Salmonella infection. J. Immunol. 178: 5789-5801.
16. + myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. Blood 113: 3190-3197.
17. Ko, H. J., J. L. Brady, V. Ryg-Cornejo, D. S. Hansen, D. Vremec, K. Shortman, Y. Zhan, and A. M. Lew. 2014. GM-CSF-responsive monocyte-derived dendritic cells are pivotal in Th17 pathogenesis. J. Immunol. 192: 2202-2209.
18. Tezuka, H., Y. Abe, M. Iwata, H. Takeuchi, H. Ishikawa, M. Matsushita, T. Shiohara, S. Akira, and T. Ohteki. 2007. Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells. Nature 448: 929-933.
19. + dendritic cells for immune T cell areas. Cell 143: 416-429.
20. + dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen. Immunity 38: 322-335.
21. Segura, E., M. Touzot, A. Bohineust, A. Cappuccio, G. Chiocchia, A. Hosmalin, M. Dalod, V. Soumelis, and S. Amigorena. 2013. Human inflammatory dendritic cells induce Th17 cell differentiation. Immunity 38: 336-348.
22. + T (H)-17 cells in relapsing EAE. Nat. Immunol. 8: 172-180.
23. Zecher, D., N. van Rooijen, D. M. Rothstein, W. D. Shlomchik, and F. G. Lakkis. 2009. An innate response to allogeneic nonself mediated by monocytes. J. Immunol. 183: 7810-7816.
24. Oberbarnscheidt, M. H., Q. Zeng, Q. Li, H. Dai, A. L. Williams, W. D. Shlomchik, D. M. Rothstein, and F. G. Lakkis. 2014. Non-self recognition by monocytes initiates allograft rejection. J. Clin. Invest. 124: 3579-3589.
25. Lanzavecchia, A., and F. Sallusto. 2001. Regulation of T cell immunity by dendritic cells. Cell 106: 263-266.
26. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252.
27. Mellman, I., and R. M. Steinman. 2001. Dendritic cells: specialized and regulated antigen processing machines. Cell 106: 255-258.
28. Stock, P. G., N. L. Ascher, S. Chen, J. Field, F. H. Bach, and D. E. Sutherland. 1991. Evidence for direct and indirect pathways in the generation of the alloimmune response against pancreatic islets. Transplantation 52: 704-709.
29. Lang, R. A., D. Metcalf, R. A. Cuthbertson, I. Lyons, E. Stanley, A. Kelso, G. Kannourakis, D. J. Williamson, G. K. Klintworth, T. J. Gonda, and A. R. Dunn. 1987. Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage. Cell 51: 675-686.
30. Barnden, M. J., J. Allison, W. R. Heath, and F. R. Carbone. 1998. Defective TCR expression in transgenic mice constructed using cDNA-based a-and b-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 76: 34-40.
31. Hohl, T. M., A. Rivera, L. Lipuma, A. Gallegos, C. Shi, M. Mack, and E. G. Pamer. 2009. Inflammatory monocytes facilitate adaptive CD4 T cell re sponses during respiratory fungal infection. Cell Host Microbe 6: 470-481.
32. Vremec, D., and K. Shortman. 2008. The isolation and identification of murine dendritic cell populations from lymphoid tissues and their production in culture. Methods Mol. Biol. 415: 163-178.
33. Li, M., G. M. Davey, R. M. Sutherland, C. Kurts, A. M. Lew, C. Hirst, F. R. Carbone, and W. R. Heath. 2001. Cell-associated ovalbumin is cross-presented much more efficiently than soluble ovalbumin in vivo. J. Immunol. 166: 6099-6103.
34. Green, L. C., D. A. Wagner, J. Glogowski, P. L. Skipper, J. S. Wishnok, and S. R. Tannenbaum. 1982. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal. Biochem. 126: 131-138.
35. + spleen dendritic cells. Eur. J. Immunol. 41: 2585-2595.
36. Tamoutounour, S., M. Guilliams, F. Montanana Sanchis, H. Liu, D. Terhorst, C. Malosse, E. Pollet, L. Ardouin, H. Luche, C. Sanchez, et al. 2013. Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skin. Immunity 39: 925-938.
37. Hohl, T. M., A. Rivera, L. Lipuma, A. Gallegos, C. Shi, M. Mack, and E. G. Pamer. 2009. Inflammatory monocytes facilitate adaptive CD4 T cell responses during respiratory fungal infection. Cell Host Microbe 6: 470-481.
38. Nussenzweig, M. C., R. M. Steinman, B. Gutchinov, and Z. A. Cohn. 1980. Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes. J. Exp. Med. 152: 1070-1084.
39. Van Voorhis, W. C., J. Valinsky, E. Hoffman, J. Luban, L. S. Hair, and R. M. Steinman. 1983. Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication. J. Exp. Med. 158: 174-191.
40. Billiau, A., and P. Matthys. 2001. Modes of action of Freund's adjuvants in experimental models of autoimmune diseases. J. Leukoc. Biol. 70: 849-860.
41. Shibaki, A., and S. I. Katz. 2002. Induction of skewed Th1/Th2 T-cell differentiation via subcutaneous immunization with Freund's adjuvant. Exp. Derma-tol. 11: 126-134.
42. Victoratos, P., M. Yiangou, N. Avramidis, and L. Hadjipetrou. 1997. Regulation of cytokine gene expression by adjuvants in vivo. Clin. Exp. Immunol. 109: 569-578.
43. Segura, E., and S. Amigorena. 2013. Inflammatory dendritic cells in mice and humans. Trends Immunol. 34: 440-445.
44. Rowland, S. L., J. M. Riggs, S. Gilfillan, M. Bugatti, W. Vermi, R. Kolbeck, E. R. Unanue, M. A. Sanjuan, and M. Colonna. 2014. Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model. J. Exp. Med. 211: 1977-1991.
45. Sisirak, V., D. Ganguly, K. L. Lewis, C. Couillault, L. Tanaka, S. Bolland, V. D'Agati, K. B. Elkon, and B. Reizis. 2014. Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus. J. Exp. Med. 211: 1969-1976.
46. Xu, Y., Y. Zhan, A. M. Lew, S. H. Naik, and M. H. Kershaw. 2007. Differential development of murine dendritic cells by GM-CSF versus Flt3 ligand has implications for inflammation and trafficking. J. Immunol. 179: 7577-7584.
47. Bosschaerts, T., M. Guilliams, B. Stijlemans, P. De Baetselier, and A. Beschin. 2009. Understanding the role of monocytic cells in liver inflammation using parasite infection as a model. Immunobiology 214: 737-747.
48. Schmid, M., A. K. Wege, and U. Ritter. 2012. Characteristics of "Tip-DCs and MDSCs and their potential role in Leishmaniasis. Front. Microbiol. 3: 74.
49. Tacke, F., and G. J. Randolph. 2006. Migratory fate and differentiation of blood monocyte subsets. Immunobiology 211: 609-618.
50. Delamarre, L., M. Pack, H. Chang, I. Mellman, and E. S. Trombetta. 2005. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science 307: 1630-1634.
51. Savina, A., and S. Amigorena. 2007. Phagocytosis and antigen presentation in dendritic cells. Immunol. Rev. 219: 143-156.
52. Stuehr, D. J., and M. A. Marletta. 1985. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipo-polysaccharide. Proc. Natl. Acad. Sci. USA 82: 7738-7742.
53. Bogdan, C. 2015. Nitric oxide synthase in innate and adaptive immunity: an update. Trends Immunol. 36: 161-178.
54. Jones-Carson, J., J. Laughlin, M. A. Hamad, A. L. Stewart, M. I. Voskuil, and A. Vazquez-Torres. 2008. Inactivation of [Fe-S] metalloproteins mediates nitric oxide-dependent killing of Burkholderia mallei. PLoS One.
55. Richardson, A. R., E. C. Payne, N. Younger, J. E. Karlinsey, V. C. Thomas, L. A. Becker, W. W. Navarre, M. E. Castor, S. J. Libby, and F. C. Fang. 2011. Multiple targets of nitric oxide in the tricarboxylic acid cycle of Salmonella enterica serovar typhimurium. Cell Host Microbe 10: 33-43.
56. Müller, A. J., S. Aeschlimann, R. Olekhnovitch, M. Dacher, G. F. Späth, and P. Bousso. 2013. Photoconvertible pathogen labeling reveals nitric oxide control of Leishmania major infection in vivo via dampening of parasite metabolism. Cell Host Microbe 14: 460-467.
57. Bingisser, R. M., P. A. Tilbrook, P. G. Holt, and U. R. Kees. 1998. Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway. J. Immunol. 160: 5729-5734.
58. Slaney, C. Y., A. Toker, A. La Flamme, B. T. Bäckström, and J. L. Harper. 2011. Naive blood monocytes suppress T-cell function: aA possible mechanism for protection from autoimmunity. Immunol. Cell Biol. 89: 7-13.
59. Bogdan, C. 2011. Regulation of lymphocytes by nitric oxide. Methods Mol. Biol. 677: 375-393.
60. Arakawa, Y., J. Qin, H. S. Chou, S. Bhatt, L. Wang, D. Stuehr, A. Ghosh, J. J. Fung, L. Lu, and S. Qian. 2014. Cotransplantation with myeloid-derived suppressor cells protects cell transplants: a crucial role of inducible nitric oxide synthase. Transplantation 97: 740-747.
61. + myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvi-ronment. Cancer Res. 72: 876-886.
62. Ostrand-Rosenberg, S., and P. Sinha. 2009. Myeloid-derived suppressor cells: linking inflammation and cancer. J. Immunol. 182: 4499-4506.
63. Pulendran, B. 2004. Modulating TH1/TH2 responses with microbes, dendritic cells, and pathogen recognition receptors. Immunol. Res. 29: 187-196.
64. - subclasses of dendritic cells direct the development of distinct T helper cells in vivo. J. Exp. Med. 189: 587-592.
65. Pulendran, B., J. L. Smith, G. Caspary, K. Brasel, D. Pettit, E. Maraskovsky, and C. R. Maliszewski. 1999. Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. Proc. Natl. Acad. Sci. USA 96: 1036-1041.
66. Shi, C., and E. G. Pamer. 2011. Monocyte recruitment during infection and inflammation. Nat. Rev. Immunol. 11: 762-774.