메뉴 건너뛰기




Volumn 81, Issue 11, 2016, Pages H2849-H2857

Daily Ingestion of Aloe Vera Gel Powder Containing Aloe Sterols Prevents Skin Photoaging in OVX Hairless Mice

Author keywords

Aloe vera gel; EGF; estrogen deficiency; MMPs; photoaging

Indexed keywords


EID: 84994330208     PISSN: 00221147     EISSN: 17503841     Source Type: Journal    
DOI: 10.1111/1750-3841.13527     Document Type: Article
Times cited : (10)

References (62)
  • 3
    • 73249142735 scopus 로고    scopus 로고
    • Dietary Aloe Vera supplementation improves facial wrinkles and elasticity and it increases the Type I procollagen gene expression in human skin in vivo
    • Cho S, Lee S, Lee MJ, Lee DH, Won CH, Kim SM, Chung JH. 2009. Dietary Aloe Vera supplementation improves facial wrinkles and elasticity and it increases the Type I procollagen gene expression in human skin in vivo. Ann Dermatol 21:6–11.
    • (2009) Ann Dermatol , vol.21 , pp. 6-11
    • Cho, S.1    Lee, S.2    Lee, M.J.3    Lee, D.H.4    Won, C.H.5    Kim, S.M.6    Chung, J.H.7
  • 4
    • 5144224411 scopus 로고    scopus 로고
    • A review on the relationship between Aloe vera components and their biologic effects
    • Choi S, Chung MH. 2003. A review on the relationship between Aloe vera components and their biologic effects. Semin Integr Med 1:53–62.
    • (2003) Semin Integr Med , vol.1 , pp. 53-62
    • Choi, S.1    Chung, M.H.2
  • 5
    • 84925943909 scopus 로고    scopus 로고
    • Keratinocyte differentiation and upregulation of ceramide synthesis induced by an oat lipid extract via the activation of PPAR pathways
    • Chon SH, Tannahill R, Yao X, Southall MD, Pappas A. 2015. Keratinocyte differentiation and upregulation of ceramide synthesis induced by an oat lipid extract via the activation of PPAR pathways. Exp Dermatol 24:290–5.
    • (2015) Exp Dermatol , vol.24 , pp. 290-295
    • Chon, S.H.1    Tannahill, R.2    Yao, X.3    Southall, M.D.4    Pappas, A.5
  • 6
    • 0033889654 scopus 로고    scopus 로고
    • Decreased extracellular-signal-regulated kinase and increased stress-activated MAP kinase activities in aged human skin in vivo
    • Chung JH, Kang S, Varani J, Lin J, Fisher GJ, Voorhees JJ. 2000. Decreased extracellular-signal-regulated kinase and increased stress-activated MAP kinase activities in aged human skin in vivo. J Invest Dermatol 115:177–82.
    • (2000) J Invest Dermatol , vol.115 , pp. 177-182
    • Chung, J.H.1    Kang, S.2    Varani, J.3    Lin, J.4    Fisher, G.J.5    Voorhees, J.J.6
  • 7
    • 84872854089 scopus 로고    scopus 로고
    • Effects of collagen and collagen hydrolysate from jellyfish umbrella on histological and immunity changes of mice photoaging
    • Fan J, Zhuang Y, Li B. 2013. Effects of collagen and collagen hydrolysate from jellyfish umbrella on histological and immunity changes of mice photoaging. Nutrients 5:223–33.
    • (2013) Nutrients , vol.5 , pp. 223-233
    • Fan, J.1    Zhuang, Y.2    Li, B.3
  • 8
    • 0022543938 scopus 로고
    • Structural and functional changes of normal aging skin
    • Fenske NA, Lober CW. 1986. Structural and functional changes of normal aging skin. J Am Acad Dermatol 15:571–85.
    • (1986) J Am Acad Dermatol , vol.15 , pp. 571-585
    • Fenske, N.A.1    Lober, C.W.2
  • 9
    • 0031751566 scopus 로고    scopus 로고
    • Molecular mechanisms of photoaging and its prevention by retinoic acid: ultraviolet irradiation induces MAP kinase signal transduction cascades that induce Ap-1-regulated matrix metalloproteinases that degrade human skin in vivo
    • Fisher GJ, Voorhees JJ. 1998. Molecular mechanisms of photoaging and its prevention by retinoic acid: ultraviolet irradiation induces MAP kinase signal transduction cascades that induce Ap-1-regulated matrix metalloproteinases that degrade human skin in vivo. J Investig Dermatol Symp Proc 3:61–8.
    • (1998) J Investig Dermatol Symp Proc , vol.3 , pp. 61-68
    • Fisher, G.J.1    Voorhees, J.J.2
  • 11
    • 0020096171 scopus 로고
    • Age-associated changes in the skin
    • Gilchrest BA. 1982. Age-associated changes in the skin. J Am Geriatr Soc 30:139–43.
    • (1982) J Am Geriatr Soc , vol.30 , pp. 139-143
    • Gilchrest, B.A.1
  • 13
    • 28444467038 scopus 로고    scopus 로고
    • Ultraviolet immunosuppression: mechanisms and consequences
    • Hanneman KK, Cooper KD, Baron ED. 2006. Ultraviolet immunosuppression: mechanisms and consequences. Dermatol Clin 24:19–25.
    • (2006) Dermatol Clin , vol.24 , pp. 19-25
    • Hanneman, K.K.1    Cooper, K.D.2    Baron, E.D.3
  • 14
    • 84885099652 scopus 로고    scopus 로고
    • Chafuroside B, an Oolong tea polyphenol, ameliorates UVB-induced DNA damage and generation of photo-immunosuppression related mediators in human keratinocytes
    • Hasegawa T, Shimada S, Ishida H, Nakashima M. 2013. Chafuroside B, an Oolong tea polyphenol, ameliorates UVB-induced DNA damage and generation of photo-immunosuppression related mediators in human keratinocytes. PLoS One 8:e77308.
    • (2013) PLoS One , vol.8
    • Hasegawa, T.1    Shimada, S.2    Ishida, H.3    Nakashima, M.4
  • 16
  • 17
    • 84927596917 scopus 로고    scopus 로고
    • Biological mechanisms underlying the ultraviolet radiation-induced formation of skin wrinkling and sagging I: reduced skin elasticity, highly associated with enhanced dermal elastase activity, triggers wrinkling and sagging
    • Imokawa G, Ishida K. 2015. Biological mechanisms underlying the ultraviolet radiation-induced formation of skin wrinkling and sagging I: reduced skin elasticity, highly associated with enhanced dermal elastase activity, triggers wrinkling and sagging. Int J Mol Sci 16:7753–75.
    • (2015) Int J Mol Sci , vol.16 , pp. 7753-7775
    • Imokawa, G.1    Ishida, K.2
  • 18
    • 84927630416 scopus 로고    scopus 로고
    • Biological mechanisms underlying the ultraviolet radiation-induced formation of skin wrinkling and sagging II: over-expression of neprilysin plays an essential role
    • Imokawa G, Nakajima H, Ishida K. 2015. Biological mechanisms underlying the ultraviolet radiation-induced formation of skin wrinkling and sagging II: over-expression of neprilysin plays an essential role. Int J Mol Sci 16:7776–95.
    • (2015) Int J Mol Sci , vol.16 , pp. 7776-7795
    • Imokawa, G.1    Nakajima, H.2    Ishida, K.3
  • 20
    • 0036182866 scopus 로고    scopus 로고
    • Molecular mechanisms of skin ageing
    • Jenkins G. 2002. Molecular mechanisms of skin ageing. Mech Ageing Dev 123:801–10.
    • (2002) Mech Ageing Dev , vol.123 , pp. 801-810
    • Jenkins, G.1
  • 21
    • 66249125012 scopus 로고    scopus 로고
    • Acemannan stimulates gingival fibroblast proliferation; expressions of keratinocyte growth factor-1, vascular endothelial growth factor, and type I collagen; and wound healing
    • Jettanacheawchankit S, Sasithanasate S, Sangvanich P, Banlunara W, Thunyakitpisal P. 2009. Acemannan stimulates gingival fibroblast proliferation; expressions of keratinocyte growth factor-1, vascular endothelial growth factor, and type I collagen; and wound healing. J Pharmacol Sci 109:525–31.
    • (2009) J Pharmacol Sci , vol.109 , pp. 525-531
    • Jettanacheawchankit, S.1    Sasithanasate, S.2    Sangvanich, P.3    Banlunara, W.4    Thunyakitpisal, P.5
  • 22
    • 0030020568 scopus 로고    scopus 로고
    • Estrogen inhibits interleukin-6 production and gene expression in a human osteoblastic cell line with high levels of estrogen receptors
    • Kassem M, Harris SA, Spelsberg TC, Riggs BL. 1996. Estrogen inhibits interleukin-6 production and gene expression in a human osteoblastic cell line with high levels of estrogen receptors. J Bone Miner Res 11:193–9.
    • (1996) J Bone Miner Res , vol.11 , pp. 193-199
    • Kassem, M.1    Harris, S.A.2    Spelsberg, T.C.3    Riggs, B.L.4
  • 25
    • 0028987267 scopus 로고
    • 1,25-Dihydroxyvitamin D3 enhances the expression of transforming growth factor beta 1 and its latent form binding protein in cultured breast carcinoma cells
    • Koli K, Keski-Oja J. 1995. 1,25-Dihydroxyvitamin D3 enhances the expression of transforming growth factor beta 1 and its latent form binding protein in cultured breast carcinoma cells. Cancer Res 55:1540–6.
    • (1995) Cancer Res , vol.55 , pp. 1540-1546
    • Koli, K.1    Keski-Oja, J.2
  • 26
    • 84856596636 scopus 로고    scopus 로고
    • Potential of herbs in skin protection from ultraviolet radiation
    • Korać RR, Khambholja KM. 2011. Potential of herbs in skin protection from ultraviolet radiation. Pharmacogn Rev 5:164–73.
    • (2011) Pharmacogn Rev , vol.5 , pp. 164-173
    • Korać, R.R.1    Khambholja, K.M.2
  • 27
    • 0035990431 scopus 로고    scopus 로고
    • MMP-2, TIMP-2 and MT1-MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB-light
    • Krengel S, Alexander M, Brinckmann J, Tronnier M. 2002. MMP-2, TIMP-2 and MT1-MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB-light. J Cutan Pathol 29:390–6.
    • (2002) J Cutan Pathol , vol.29 , pp. 390-396
    • Krengel, S.1    Alexander, M.2    Brinckmann, J.3    Tronnier, M.4
  • 29
    • 77952243245 scopus 로고    scopus 로고
    • Role of antioxidants in the skin: anti-aging effects
    • Masaki H. 2010. Role of antioxidants in the skin: anti-aging effects. J Dermatol Sci 58:85–90.
    • (2010) J Dermatol Sci , vol.58 , pp. 85-90
    • Masaki, H.1
  • 30
    • 0034456931 scopus 로고    scopus 로고
    • Estrogen modulates parathyroid hormone-induced interleukin-6 production in vivo and in vitro
    • Masiukiewicz US, Mitnick M, Grey AB, Insogna KL. 2000. Estrogen modulates parathyroid hormone-induced interleukin-6 production in vivo and in vitro. Endocrinology 141:2526–31.
    • (2000) Endocrinology , vol.141 , pp. 2526-2531
    • Masiukiewicz, U.S.1    Mitnick, M.2    Grey, A.B.3    Insogna, K.L.4
  • 33
    • 78650043649 scopus 로고    scopus 로고
    • Neprilysin is identical to skin fibroblast elastase: its role in skin aging and UV responses
    • Morisaki N, Moriwaki S, Sugiyama-Nakagiri Y, Haketa K, Takema Y, Imokawa G. 2010. Neprilysin is identical to skin fibroblast elastase: its role in skin aging and UV responses. J Biol Chem 285:39819–27.
    • (2010) J Biol Chem , vol.285 , pp. 39819-39827
    • Morisaki, N.1    Moriwaki, S.2    Sugiyama-Nakagiri, Y.3    Haketa, K.4    Takema, Y.5    Imokawa, G.6
  • 34
    • 80051693270 scopus 로고    scopus 로고
    • Aloe vera phytosterols act as ligands for PPAR and improve the expression levels of PPAR target genes in the livers of mice with diet-induced obesity
    • Nomaguchi K, Tanaka M, Misawa E, Yamada M, Toida T, Iwatsuki K, Goto T, Kawada T. 2011. Aloe vera phytosterols act as ligands for PPAR and improve the expression levels of PPAR target genes in the livers of mice with diet-induced obesity. Obes Res Clin Pract 5:e169–266.
    • (2011) Obes Res Clin Pract , vol.5 , pp. e169-266
    • Nomaguchi, K.1    Tanaka, M.2    Misawa, E.3    Yamada, M.4    Toida, T.5    Iwatsuki, K.6    Goto, T.7    Kawada, T.8
  • 36
    • 77955815909 scopus 로고    scopus 로고
    • Effect of aqueous extract of Aloe vera on experimental cutaneous wound healing in rat
    • Oryan AT, Naeini A, Nikahval B, Gorjia E. 2010. Effect of aqueous extract of Aloe vera on experimental cutaneous wound healing in rat. Vet Arch 80:509–22.
    • (2010) Vet Arch , vol.80 , pp. 509-522
    • Oryan, A.T.1    Naeini, A.2    Nikahval, B.3    Gorjia, E.4
  • 37
    • 0019192808 scopus 로고
    • The roles of hyaluronic acid, collagen and elastin in the mechanical properties of connective tissues
    • Oxlund H, Andreassen TT. 1980. The roles of hyaluronic acid, collagen and elastin in the mechanical properties of connective tissues. J Anat 131:611–20.
    • (1980) J Anat , vol.131 , pp. 611-620
    • Oxlund, H.1    Andreassen, T.T.2
  • 39
    • 79954578979 scopus 로고    scopus 로고
    • Photoprotection by honeybush extracts, hesperidin and mangiferin against UVB-induced skin damage in SKH-1 mice
    • Petrova A, Davids LM, Rautenbach F, Marnewick JL. 2011. Photoprotection by honeybush extracts, hesperidin and mangiferin against UVB-induced skin damage in SKH-1 mice. J Photochem Photobiol B Biol 103:126–39.
    • (2011) J Photochem Photobiol B Biol , vol.103 , pp. 126-139
    • Petrova, A.1    Davids, L.M.2    Rautenbach, F.3    Marnewick, J.L.4
  • 41
    • 0028180435 scopus 로고
    • 17 beta-Estradiol inhibits expression of human interleukin-6 promoter-reporter constructs by a receptor-dependent mechanism
    • Pottratz ST, Bellido T, Mocharla H, Crabb D, Manolagas SC. 1994. 17 beta-Estradiol inhibits expression of human interleukin-6 promoter-reporter constructs by a receptor-dependent mechanism. J Clin Invest 93:944–50.
    • (1994) J Clin Invest , vol.93 , pp. 944-950
    • Pottratz, S.T.1    Bellido, T.2    Mocharla, H.3    Crabb, D.4    Manolagas, S.C.5
  • 42
    • 0034121565 scopus 로고    scopus 로고
    • Modified Aloe barbadensis polysaccharide with immunoregulatory activity
    • Qiu Z, Jones K, Wylie M, Jia Q, Orndorff S. 2000. Modified Aloe barbadensis polysaccharide with immunoregulatory activity. Planta Med 66:152–6.
    • (2000) Planta Med , vol.66 , pp. 152-156
    • Qiu, Z.1    Jones, K.2    Wylie, M.3    Jia, Q.4    Orndorff, S.5
  • 43
    • 0032744713 scopus 로고    scopus 로고
    • Aloe vera leaf gel: a review update
    • Reynolds T, Dweck AC. 1999. Aloe vera leaf gel: a review update. J Ethnopharmacol 68:3–37.
    • (1999) J Ethnopharmacol , vol.68 , pp. 3-37
    • Reynolds, T.1    Dweck, A.C.2
  • 44
    • 0036724946 scopus 로고    scopus 로고
    • UV-light-induced signal cascades and skin aging
    • Rittié L, Fisher GJ. 2002. UV-light-induced signal cascades and skin aging. Ageing Res Rev 1:705–20.
    • (2002) Ageing Res Rev , vol.1 , pp. 705-720
    • Rittié, L.1    Fisher, G.J.2
  • 46
    • 79953014066 scopus 로고    scopus 로고
    • Targeting inflammation by modulating the Jun/AP-1 pathway
    • Schonthaler HB, Guinea-Viniegra J, Wagner EF. 2011. Targeting inflammation by modulating the Jun/AP-1 pathway. Ann Rheum Dis 70(Suppl 1):i109–12.
    • (2011) Ann Rheum Dis , vol.1 , Issue.70Suppl , pp. i109-i112
    • Schonthaler, H.B.1    Guinea-Viniegra, J.2    Wagner, E.F.3
  • 47
    • 2442707519 scopus 로고    scopus 로고
    • Effects of aging and postmenopausal hypoestrogenism on skin elasticity and bone mineral density in Japanese women
    • Sumino H, Ichikawa S, Abe M, Endo Y, Nakajima Y, Minegishi T, Ishikawa O, Kurabayashi M. 2004. Effects of aging and postmenopausal hypoestrogenism on skin elasticity and bone mineral density in Japanese women. Endocr J 51:159–64.
    • (2004) Endocr J , vol.51 , pp. 159-164
    • Sumino, H.1    Ichikawa, S.2    Abe, M.3    Endo, Y.4    Nakajima, Y.5    Minegishi, T.6    Ishikawa, O.7    Kurabayashi, M.8
  • 48
    • 84896719895 scopus 로고    scopus 로고
    • Polysaccharides of Aloe vera induce MMP-3 and TIMP-2 gene expression during the skin wound repair of rat
    • Tabandeh MR, Oryan A, Mohammadalipour A. 2014. Polysaccharides of Aloe vera induce MMP-3 and TIMP-2 gene expression during the skin wound repair of rat. Int J Biol Macromol 65:424–30.
    • (2014) Int J Biol Macromol , vol.65 , pp. 424-430
    • Tabandeh, M.R.1    Oryan, A.2    Mohammadalipour, A.3
  • 49
    • 78649516683 scopus 로고    scopus 로고
    • Neutrophil elastase contributes to extracellular matrix damage induced by chronic low-dose UV irradiation in a hairless mouse photoaging model
    • Takeuchi H, Gomi T, Shishido M, Watanabe H, Suenobu N. 2010. Neutrophil elastase contributes to extracellular matrix damage induced by chronic low-dose UV irradiation in a hairless mouse photoaging model. J Dermatol Sci 60:151–8.
    • (2010) J Dermatol Sci , vol.60 , pp. 151-158
    • Takeuchi, H.1    Gomi, T.2    Shishido, M.3    Watanabe, H.4    Suenobu, N.5
  • 51
    • 84923343095 scopus 로고    scopus 로고
    • Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women
    • Tanaka M, Misawa E, Yamauchi K, Abe F, Ishizaki C. 2015. Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women. Clin Cosmet Investig Dermatol 8:95–104.
    • (2015) Clin Cosmet Investig Dermatol , vol.8 , pp. 95-104
    • Tanaka, M.1    Misawa, E.2    Yamauchi, K.3    Abe, F.4    Ishizaki, C.5
  • 52
    • 0042178374 scopus 로고    scopus 로고
    • The biological actions of estrogens on skin
    • Thornton MJ. 2002. The biological actions of estrogens on skin. Exp Dermatol 11:487–502.
    • (2002) Exp Dermatol , vol.11 , pp. 487-502
    • Thornton, M.J.1
  • 53
    • 9644278091 scopus 로고    scopus 로고
    • Ovariectomy is sufficient to accelerate spontaneous skin ageing and to stimulate ultraviolet irradiation-induced photoageing of murine skin
    • Tsukahara K, Nakagawa H, Moriwaki S, Kakuo S, Ohuchi A, Takema Y, Imokawa G. 2004. Ovariectomy is sufficient to accelerate spontaneous skin ageing and to stimulate ultraviolet irradiation-induced photoageing of murine skin. Br J Dermatol 151:984–94.
    • (2004) Br J Dermatol , vol.151 , pp. 984-994
    • Tsukahara, K.1    Nakagawa, H.2    Moriwaki, S.3    Kakuo, S.4    Ohuchi, A.5    Takema, Y.6    Imokawa, G.7
  • 54
    • 38649105762 scopus 로고    scopus 로고
    • The characteristics of aromatase deficient hairless mice indicate important roles of extragonadal estrogen in the skin
    • Tsukahara K, Kakuo S, Moriwaki S, Hotta M, Ohuchi A, Kitahara T, Harada N. 2008. The characteristics of aromatase deficient hairless mice indicate important roles of extragonadal estrogen in the skin. J Steroid Biochem Mol Biol 108:82–90.
    • (2008) J Steroid Biochem Mol Biol , vol.108 , pp. 82-90
    • Tsukahara, K.1    Kakuo, S.2    Moriwaki, S.3    Hotta, M.4    Ohuchi, A.5    Kitahara, T.6    Harada, N.7
  • 55
    • 0030724722 scopus 로고    scopus 로고
    • Understanding premature skin aging
    • Uitto J. 1997. Understanding premature skin aging. N Engl J Med 337:1463–5.
    • (1997) N Engl J Med , vol.337 , pp. 1463-1465
    • Uitto, J.1
  • 57
    • 34249800666 scopus 로고    scopus 로고
    • Skin hydration: a review on its molecular mechanisms
    • Verdier-Sévrain S, Bonté F. 2007. Skin hydration: a review on its molecular mechanisms. J Cosmet Dermatol 6:75–82.
    • (2007) J Cosmet Dermatol , vol.6 , pp. 75-82
    • Verdier-Sévrain, S.1    Bonté, F.2
  • 58
    • 33645125574 scopus 로고    scopus 로고
    • Biology of estrogens in skin: implications for skin aging
    • Verdier-Sévrain S, Bonté F, Gilchrest B. 2006. Biology of estrogens in skin: implications for skin aging. Exp Dermatol 15:83–94.
    • (2006) Exp Dermatol , vol.15 , pp. 83-94
    • Verdier-Sévrain, S.1    Bonté, F.2    Gilchrest, B.3
  • 61
    • 28944439289 scopus 로고    scopus 로고
    • Antioxidant properties and PC12 cell protective effects of APS-1, a polysaccharide from Aloe vera var. chinensis
    • Wu JH, Xu C, Shan CY, Tan RX. 2006. Antioxidant properties and PC12 cell protective effects of APS-1, a polysaccharide from Aloe vera var. chinensis. Life Sci 78:622–30.
    • (2006) Life Sci , vol.78 , pp. 622-630
    • Wu, J.H.1    Xu, C.2    Shan, C.Y.3    Tan, R.X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.