Doping the Mind: Dopaminergic Modulation of Prefrontal Cortical Cognition

Neuroscientist

Volumn 22, Issue 6, 2016, Pages 593-603

  Ranganath, Ajit ^a   Jacob, Simon N ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

cognitive control; dopamine; neuromodulation; nonhuman primate; prefrontal cortex

Indexed keywords

DOPAMINE;

ATTENTION; CELL FUNCTION; COGNITION; COGNITIVE DEFECT; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; EXECUTIVE FUNCTION; FRONTAL LOBE; HUMAN; MESENCEPHALON; MOOD DISORDER; MOTIVATION; NEUROANATOMY; NEUROMODULATION; NEUROPHYSIOLOGY; NONHUMAN; PREFRONTAL CORTEX; PRIMATE; PRIORITY JOURNAL; REVIEW; STATE DEPENDENT LEARNING; THINKING; VISION; WORKING MEMORY; ANIMAL; BIOLOGICAL MODEL; METABOLISM; NERVE CELL; PHYSIOLOGY;

ANIMALS; ATTENTION; COGNITION; DOPAMINE; HUMANS; MODELS, NEUROLOGICAL; NEURONS; PREFRONTAL CORTEX;

EID: 84994275853     PISSN: 10738584     EISSN: 10894098     Source Type: Journal    
DOI: 10.1177/1073858415602850     Document Type: Review

References (87)

1. Abi-Dargham A, Mawlawi O, Lombardo I, Gil R, Martinez D, Huang Y, and others. 2002. Prefrontal dopamine D1 receptors and working memory in schizophrenia. J Neurosci 22: 3708-19.
2. 11C]NNC112. J Psychopharmacol. (Oxford) 26: 794-805.
3. Baddeley A., 1992. Working memory. Science 255: 556-9.
4. Baddeley A., 2000. The episodic buffer: a new component of working memory? Trends Cogn Sci. 4: 417-23.
5. Baluch F, Itti L., 2011. Mechanisms of top-down attention. Trends Neurosci 34: 210-24.
6. Barbas H,. 1988. Anatomic organization of basoventral and mediodorsal visual recipient prefrontal regions in the rhesus monkey. J Comp Neurol 276: 313-42.
7. Barbas H, Mesulam MM,. 1985. Cortical afferent input to the principalis region of the rhesus monkey. Neuroscience 15: 619-37.
8. Bates JF, Goldman-Rakic PS,. 1993. Prefrontal connections of medial motor areas in the rhesus monkey. J Comp Neurol 336: 211-28.
9. Berridge CW, Devilbiss DM,. 2011. Psychostimulants as cognitive enhancers: the prefrontal cortex, catecholamines, and attention-deficit/hyperactivity disorder. Biol Psychiatry 69: e101-11.
10. Bongard S, Nieder A., 2010. Basic mathematical rules are encoded by primate prefrontal cortex neurons. Proc Natl Acad Sci U S A 107: 2277-82.
11. Brozoski TJ, Brown RM, Rosvold HE, Goldman PS,. 1979. Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. Science 205: 929-32.
12. Carr DB, Sesack SR,. 2000. Projections from the rat prefrontal cortex to the ventral tegmental area: target specificity in the synaptic associations with mesoaccumbens and mesocortical neurons. J Neurosci 20: 3864-73.
13. Caylak E,. 2012. Biochemical and genetic analyses of childhood attention deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 159B: 613-27.
14. Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, and others. 2013. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature 493: 532-6.
15. Chu Y, Kompoliti K, Cochran EJ, Mufson EJ, Kordower JH,. 2002. Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra. J. Comp. Neurol. 450: 203-214.
16. Chun S, Westmoreland JJ, Bayazitov IT, Eddins D, Pani AK, Smeyne RJ, and others. 2014. Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models. Science 344: 1178-82.
17. Cools R, Miyakawa A, Sheridan M, D'Esposito M., 2010. Enhanced frontal function in Parkinson's disease. Brain 133: 225-33.
18. Cummings JL,. 1995. Anatomic and behavioral aspects of frontal-subcortical circuits. Ann N Y Acad Sci 769: 1-13.
19. Deutch AY, Goldstein M, Baldino F, Roth RH,. 1988. Telencephalic projections of the A8 dopamine cell group. Ann N Y Acad Sci 537: 27-50.
20. Eisenberg DP, Berman KF,. 2010. Executive function, neural circuitry, and genetic mechanisms in schizophrenia. Neuropsychopharmacology 35: 258-77.
21. Emborg ME, Ma SY, Mufson EJ, Levey AI, Taylor MD, Brown WD, and others. 1998. Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys. J Comp Neurol 401: 253-65.
22. Fletcher PC, Frith CD,. 2009. Perceiving is believing: a Bayesian approach to explaining the positive symptoms of schizophrenia. Nat Rev Neurosci 10: 48-58.
23. Floresco SB, Magyar O, Ghods-Sharifi S, Vexelman C, Tse MTL,. 2006. Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting. Neuropsychopharmacology 31: 297-309.
24. Fuster JM, Alexander GE,. 1971. Neuron activity related to short-term memory. Science 173: 652-4.
25. German DC, Manaye KF,. 1993. Midbrain dopaminergic neurons (nuclei A8, A9, and A10): three-dimensional reconstruction in the rat. J Comp Neurol 331: 297-309.
26. Goldman-Rakic PS, Leranth C, Williams SM, Mons N, Geffard M., 1989. Dopamine synaptic complex with pyramidal neurons in primate cerebral cortex. Proc Natl Acad Sci U S A 86: 9015-9.
27. Goldman-Rakic PS, Lidow MS, Smiley JF, Williams MS,. 1992. The anatomy of dopamine in monkey and human prefrontal cortex. J Neural Transm Suppl 36: 163-77.
28. Howes OD, Kapur S., 2009. The dopamine hypothesis of schizophrenia: version III-the final common pathway. Schizophr Bull 35: 549-62.
29. Jacob SN, Nieder A., 2014. Complementary roles for primate frontal and parietal cortex in guarding working memory from distractor stimuli. Neuron 83: 226-37.
30. Jacob SN, Ott T, Nieder A., 2013. Dopamine regulates two classes of primate prefrontal neurons that represent sensory signals. J Neurosci 33: 13724-34.
31. Kapur S,. 2003. Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia. Am J Psychiatry 160: 13-23.
32. Kim IH, Rossi MA, Aryal DK, Racz B, Kim N, Uezu A, and others. 2015. Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine. Nat Neurosci 18: 883-91.
33. Kubota K, Niki H., 1971. Prefrontal cortical unit activity and delayed alternation performance in monkeys. J Neurophysiol 34: 337-47.
34. Lachowicz JE, Sibley DR,. 1997. Molecular characteristics of mammalian dopamine receptors. Pharmacol Toxicol 81: 105-13.
35. Lammel S, Steinberg EE, Földy C, Wall NR, Beier K, Luo L, and others. 2015. Diversity of transgenic mouse models for selective targeting of midbrain dopamine neurons. Neuron 85: 429-38.
36. Lidow MS, Goldman-Rakic PS, Gallager DW, Rakic P., 1991. Distribution of dopaminergic receptors in the primate cerebral cortex: quantitative autoradiographic analysis using [3H]raclopride, [3H]spiperone and [3H]SCH23390. Neuroscience 40: 657-71.
37. Lidow MS, Wang F, Cao Y, Goldman-Rakic PS,. 1998. Layer V neurons bear the majority of mRNAs encoding the five distinct dopamine receptor subtypes in the primate prefrontal cortex. Synapse 28: 10-20.
38. Marder E,. 2012. Neuromodulation of neuronal circuits: back to the future. Neuron 76: 1-11.
39. Matsumoto M, Hikosaka O., 2009. Two types of dopamine neuron distinctly convey positive and negative motivational signals. Nature 459: 837-41.
40. Matsumoto M, Takada M., 2013. Distinct representations of cognitive and motivational signals in midbrain dopamine neurons. Neuron 79: 1011-24.
41. Mattay VS, Tessitore A, Callicott JH, Bertolino A, Goldberg TE, Chase TN, and others. 2002. Dopaminergic modulation of cortical function in patients with Parkinson's disease. Ann Neurol 51: 156-64.
42. Meyer-Lindenberg A, Miletich RS, Kohn PD, Esposito G, Carson RE, Quarantelli M, and others. 2002. Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia. Nat Neurosci 5: 267-71.
43. Miller EK, Cohen JD,. 2001. An integrative theory of prefrontal cortex function. Annu Rev Neurosci 24: 167-202.
44. Milner B,. 1963. Effects of different brain lesions on card sorting. Arch Neurol 9: 90-100.
45. Missale C, Nash SR, Robinson SW, Jaber M, Caron MG,. 1998. Dopamine receptors: from structure to function. Physiol Rev 78: 189-225.
46. Mizoguchi K, Yuzurihara M, Ishige A, Sasaki H, Chui DH, Tabira T., 2000. Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction. J Neurosci 20: 1568-74.
47. Moore T, Armstrong KM,. 2003. Selective gating of visual signals by microstimulation of frontal cortex. Nature 421: 370-3.
48. Mueser KT, McGurk SR,. 2004. Schizophrenia. Lancet 363: 2063-72.
49. Nelson EL, Liang CL, Sinton CM, German DC,. 1996. Midbrain dopaminergic neurons in the mouse: computer-assisted mapping. J Comp Neurol 369: 361-71.
50. Noudoost B, Moore T., 2011. Control of visual cortical signals by prefrontal dopamine. Nature 474: 372-5.
51. Nutt DJ, Lingford-Hughes A, Erritzoe D, Stokes PRA,. 2015. The dopamine theory of addiction: 40 years of highs and lows. Nat Rev Neurosci 16: 305-12.
52. Okubo Y, Suhara T, Suzuki K, Kobayashi K, Inoue O, Terasaki O, and others. 1997. Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET. Nature 385: 634-6.
53. Ott T, Jacob SN, Nieder A., 2014. Dopamine receptors differentially enhance rule coding in primate prefrontal cortex neurons. Neuron 84: 1317-28.
54. Paxinos G, Franklin KBJ,. 2012. Paxinos and Franklin's: the mouse brain in stereotaxic coordinates. New York, NY: Academic Press.
55. Petrides M., 1982. Motor conditional associative-learning after selective prefrontal lesions in the monkey. Behav Brain Res 5: 407-13.
56. Preuss TM., 1995. Do rats have prefrontal cortex? The Rose-Woolsey-Akert program reconsidered. J Cogn Neurosci 7: 1-24.
57. Puig MV, Miller EK,. 2015. Neural substrates of dopamine D2 receptor modulated executive functions in the monkey prefrontal cortex. Cereb Cortex 25: 2980-87.
58. Puig MV, Miller EK,. 2012. The role of prefrontal dopamine D1 receptors in the neural mechanisms of associative learning. Neuron 74: 874-86.
59. Ragozzino ME,. 2002. The effects of dopamine D(1) receptor blockade in the prelimbic-infralimbic areas on behavioral flexibility. Learn Mem 9: 18-28.
60. Robbins TW, Cools R., 2014. Cognitive deficits in Parkinson's disease: a cognitive neuroscience perspective. Mov Disord. 29: 597-607.
61. Roberts AC, De Salvia MA, Wilkinson LS, Collins P, Muir JL, Everitt BJ, and others. 1994. 6-Hydroxydopamine lesions of the prefrontal cortex in monkeys enhance performance on an analog of the Wisconsin Card Sort Test: possible interactions with subcortical dopamine. J Neurosci 14: 2531-44.
62. Rolls ET, Loh M, Deco G, Winterer G., 2008. Computational models of schizophrenia and dopamine modulation in the prefrontal cortex. Nat Rev Neurosci 9: 696-709.
63. Russo SJ, Nestler EJ,. 2013. The brain reward circuitry in mood disorders. Nat Rev Neurosci 14: 609-25.
64. Santana N, Mengod G, Artigas F., 2009. Quantitative analysis of the expression of dopamine D1 and D2 receptors in pyramidal and GABAergic neurons of the rat prefrontal cortex. Cereb Cortex 19: 849-60.
65. Saunders A, Oldenburg IA, Berezovskii VK, Johnson CA, Kingery ND, Elliott HL, and others. 2015. A direct GABAergic output from the basal ganglia to frontal cortex. Nature 521: 85-9.
66. Sawaguchi T, Goldman-Rakic PS,. 1991. D1 dopamine receptors in prefrontal cortex: involvement in working memory. Science 251: 947-50.
67. Schultz W,. 2007. Multiple dopamine functions at different time courses. Annu Rev Neurosci 30: 259-88.
68. Schultz W, Apicella P, Ljungberg T., 1993. Responses of monkey dopamine neurons to reward and conditioned stimuli during successive steps of learning a delayed response task. J Neurosci 13: 900-13.
69. Schultz W, Dayan P, Montague PR,. 1997. A neural substrate of prediction and reward. Science 275: 1593-9.
70. Seeman P,. 2011. All roads to schizophrenia lead to dopamine supersensitivity and elevated dopamine D2(high) receptors. CNS Neurosci Ther 17: 118-32.
71. Seeman P, Lee T., 1975. Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons. Science 188: 1217-9.
72. Seidman LJ, Valera EM, Makris N., 2005. Structural brain imaging of attention-deficit/hyperactivity disorder. Biol Psychiatry 57: 1263-72.
73. Sidiropoulou K, Lu FM, Fowler MA, Xiao R, Phillips C, Ozkan ED, and others. 2009. Dopamine modulates an mGluR5-mediated depolarization underlying prefrontal persistent activity. Nat Neurosci 12: 190-9.
74. Smiley JF, Levey AI, Ciliax BJ, Goldman-Rakic PS,. 1994. D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: predominant and extrasynaptic localization in dendritic spines. Proc Natl Acad Sci U S A 91: 5720-4.
75. St Onge JR, Stopper CM, Zahm DS, Floresco SB,. 2012. Separate prefrontal-subcortical circuits mediate different components of risk-based decision making. J Neurosci 32: 2886-99.
76. Tye KM, Mirzabekov JJ, Warden MR, Ferenczi EA, Tsai HC, Finkelstein J, and others. 2013. Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Nature 493: 537-41.
77. Vertes RP,. 2003. Differential projections of the infralimbic and prelimbic cortex in the rat. Synapse 51: 32-58.
78. Vijayraghavan S, Wang M, Birnbaum SG, Williams GV, Arnsten AFT,. 2007. Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory. Nat Neurosci 10: 376-84.
79. Wallis JD, Anderson KC, Miller EK,. 2001. Single neurons in prefrontal cortex encode abstract rules. Nature 411: 953-6.
80. Wang M, Ramos BP, Paspalas CD, Shu Y, Simen A, Duque A, and others. 2007. Alpha2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell 129: 397-410.
81. Wang M, Vijayraghavan S, Goldman-Rakic PS,. 2004. Selective D2 receptor actions on the functional circuitry of working memory. Science 303: 853-6.
82. Wang M, Yang Y, Wang CJ, Gamo NJ, Jin LE, Mazer JA, and others. 2013. NMDA receptors subserve persistent neuronal firing during working memory in dorsolateral prefrontal cortex. Neuron 77: 736-49.
83. Watanabe M, Kodama T, Hikosaka K., 1997. Increase of extracellular dopamine in primate prefrontal cortex during a working memory task. J Neurophysiol 78: 2795-8.
84. Williams GV, Goldman-Rakic PS,. 1995. Modulation of memory fields by dopamine D1 receptors in prefrontal cortex. Nature 376: 572-5.
85. Williams SM, Goldman-Rakic PS,. 1998. Widespread origin of the primate mesofrontal dopamine system. Cereb Cortex 8: 321-45.
86. Winterer G, Weinberger DR,. 2004. Genes, dopamine and cortical signal-to-noise ratio in schizophrenia. Trends Neurosci 27: 683-90.
87. Yang CR, Seamans JK,. 1996. Dopamine D1 receptor actions in layers V-VI rat prefrontal cortex neurons in vitro: modulation of dendritic-somatic signal integration. J Neurosci 16: 1922-35.