Clinical next generation sequencing outperforms standard microbiological culture for characterizing polymicrobial samples

Clinical Chemistry

Volumn 62, Issue 11, 2016, Pages 1465-1473

  Cummings, Lisa A ^a   Kurosawa, Kyoko ^a   Hoogestraat, Daniel R ^a   SenGupta, Dhruba J ^a   Candra, Febrian ^a   Doyle, Michael ^a   Thielges, Stephanie ^a   Land, Tyler A ^a   Rosenthal, Christopher A ^a   Hoffman, Noah G ^a   Salipante, Stephen J ^a   Cookson, Brad T ^a,b  

^a UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL RNA; GENOMIC DNA; RNA 16S; BACTERIAL DNA;

ACHROMOBACTER XYLOSOXIDANS; AMPLICON; ARTICLE; BACTERIUM CULTURE; BRAIN ABSCESS; BURKHOLDERIA CEPACIA; BURKHOLDERIA CEPACIA COMPLEX; CLINICAL ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; CULTURE MEDIUM; CYSTIC FIBROSIS; DILUTION; DNA EXTRACTION; DRUG MIXTURE; HUMAN; LIMIT OF DETECTION; LUNG FIBROSIS; NEXT GENERATION SEQUENCING; NONHUMAN; OPERON; POLYMERASE CHAIN REACTION; PREVOTELLA; PSEUDOMONAS AERUGINOSA; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; STANDARD; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS AGALACTIAE; TARGET ORGANISM; VEILLONELLA; WORKFLOW; BACTERIAL INFECTIONS; COMPARATIVE STUDY; DNA SEQUENCE; GENETICS; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; STANDARDS; TRENDS;

BACTERIAL INFECTIONS; DNA, BACTERIAL; HUMANS; MICROBIOLOGICAL TECHNIQUES; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA;

EID: 84994136074     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2016.258806     Document Type: Article

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