High-Accuracy HLA Type Inference from Whole-Genome Sequencing Data Using Population Reference Graphs

PLoS Computational Biology

Volumn 12, Issue 10, 2016, Pages

  Dilthey, Alexander T ^a,b   Gourraud, Pierre Antoine ^c,d   Mentzer, Alexander J ^a   Cereb, Nezih ^e   Iqbal, Zamin ^a   McVean, Gil ^a,f  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITÉ DE NANTES   (France)

^e Histogenetics   (United States)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

C (PROGRAMMING LANGUAGE); CONFORMAL MAPPING; EPITOPES; GENOME; POPULATION STATISTICS;

ANTIGEN GENES; AUTOIMMUNE DISEASE; GENETIC VARIATION; HIGH-ACCURACY; HUMAN LEUKOCYTE ANTIGEN; INFECTIOUS DISEASE; READ MAPPINGS; REFERENCE GRAPHS; TYPE INFERENCES; WHOLE GENOME SEQUENCING;

GENES;

ACCURACY; ALGORITHM; ARTICLE; EXON; GENE; GENE FREQUENCY; GENE LOCUS; GENE MAPPING; GENE SEQUENCE; GENETIC VARIATION; HETEROZYGOSITY; HLA GENE; HLA TYPING; HOMOZYGOSITY; PHENOTYPE; PSEUDOGENE; SEQUENCE HOMOLOGY; CHROMOSOMAL MAPPING; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN GENOME; POPULATION GENETICS; PROCEDURES; REFERENCE VALUE;

HEMOCHROMATOSIS PROTEIN; HFE PROTEIN, HUMAN;

ALGORITHMS; CHROMOSOME MAPPING; GENETICS, POPULATION; GENOME, HUMAN; HEMOCHROMATOSIS PROTEIN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; REFERENCE VALUES;

EID: 84994101837     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1005151     Document Type: Article

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