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Volumn 7, Issue 39, 2016, Pages 63252-63260

Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer

Author keywords

Chromatin remodeling; Epigenesis; Urinary bladder neoplasm; UTX; UTY

Indexed keywords

CRISPR ASSOCIATED PROTEIN; HISTONE DEMETHYLASE; MINOR HISTOCOMPATIBILITY ANTIGEN; NUCLEAR PROTEIN; UTX PROTEIN, HUMAN; UTY PROTEIN, HUMAN;

EID: 84994056268     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11207     Document Type: Article
Times cited : (33)

References (21)
  • 2
    • 84888380730 scopus 로고    scopus 로고
    • Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation
    • Guo G, Sun X, Chen C, Wu S, Huang P, Li Z, Dean M, Huang Y, Jia W, Zhou Q, Tang A, Yang Z, Li X, et al. Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation. Nat Genet. 2013; 45:1459-1463.
    • (2013) Nat Genet , vol.45 , pp. 1459-1463
    • Guo, G.1    Sun, X.2    Chen, C.3    Wu, S.4    Huang, P.5    Li, Z.6    Dean, M.7    Huang, Y.8    Jia, W.9    Zhou, Q.10    Tang, A.11    Yang, Z.12    Li, X.13
  • 3
    • 84917689298 scopus 로고    scopus 로고
    • Long-term changes in renal function outcomes following radical cystectomy and urinary diversion
    • Nishikawa M, Miyake H, Yamashita M, Inoue TA, Fujisawa M. Long-term changes in renal function outcomes following radical cystectomy and urinary diversion. Int J Clin Oncol. 2014; 19:1105-1111.
    • (2014) Int J Clin Oncol , vol.19 , pp. 1105-1111
    • Nishikawa, M.1    Miyake, H.2    Yamashita, M.3    Inoue, T.A.4    Fujisawa, M.5
  • 5
    • 84925545335 scopus 로고    scopus 로고
    • Molecular biology of bladder cancer: new insights into pathogenesis and clinical diversity
    • Knowles MA, Hurst CD. Molecular biology of bladder cancer: new insights into pathogenesis and clinical diversity. Nat Rev Cancer. 2014; 15:25-41.
    • (2014) Nat Rev Cancer , vol.15 , pp. 25-41
    • Knowles, M.A.1    Hurst, C.D.2
  • 6
    • 79951865370 scopus 로고    scopus 로고
    • Clinical implications of the cancer genome
    • Macconaill LE, Garraway LA. Clinical implications of the cancer genome. J Clin Oncol. 2010; 28:5219-5228.
    • (2010) J Clin Oncol , vol.28 , pp. 5219-5228
    • Macconaill, L.E.1    Garraway, L.A.2
  • 11
    • 84899801975 scopus 로고    scopus 로고
    • The H3K27me3 demethylase UTX in normal development and disease
    • Van der Meulen J, Speleman F, Van Vlierberghe P. The H3K27me3 demethylase UTX in normal development and disease. Epigenetics. 2014; 9:658-668.
    • (2014) Epigenetics , vol.9 , pp. 658-668
    • Van der Meulen, J.1    Speleman, F.2    Van Vlierberghe, P.3
  • 13
    • 84868592742 scopus 로고    scopus 로고
    • Chromatin regulators with tumor suppressor properties and their alterations in human cancers
    • Shu X, Li L, Tao Q. Chromatin regulators with tumor suppressor properties and their alterations in human cancers. Epigenomics. 2012; 4:537-549.
    • (2012) Epigenomics , vol.4 , pp. 537-549
    • Shu, X.1    Li, L.2    Tao, Q.3
  • 15
    • 36749082438 scopus 로고    scopus 로고
    • Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases
    • Hong S, Cho Y, Yu L, Yu H, Veenstra TD, Ge K. Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. Proc Natl Acad Sci U S A. 2007; 104:18439-18444.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 18439-18444
    • Hong, S.1    Cho, Y.2    Yu, L.3    Yu, H.4    Veenstra, T.D.5    Ge, K.6
  • 16
    • 33747455678 scopus 로고    scopus 로고
    • JmjC-domain-containing proteins and histone demethylation
    • Klose RJ, Kallin EM, Zhang Y. JmjC-domain-containing proteins and histone demethylation. Nat Rev Genet. 2006; 7:715-727.
    • (2006) Nat Rev Genet , vol.7 , pp. 715-727
    • Klose, R.J.1    Kallin, E.M.2    Zhang, Y.3
  • 20
    • 84866912634 scopus 로고    scopus 로고
    • UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development
    • Shpargel KB, Sengoku T, Yokoyama S, Magnuson T. UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development. PLoS Genet. 2012; 8:e1002964.
    • (2012) PLoS Genet , vol.8
    • Shpargel, K.B.1    Sengoku, T.2    Yokoyama, S.3    Magnuson, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.