-
2
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012; 12:252-264.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
3
-
-
84884561907
-
Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy
-
Nirschl CJ, Drake CG. Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy. Clin Cancer Res. 2013; 19:4917-4924.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4917-4924
-
-
Nirschl, C.J.1
Drake, C.G.2
-
4
-
-
79957917538
-
Ipilimumab
-
Sondak VK, Smalley KSM, Kudchadkar R, Grippon S, Kirkpatrick P. Ipilimumab. Nat Rev Drug Discov. 2011; 10:411-412.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 411-412
-
-
Sondak, V.K.1
Smalley, K.S.M.2
Kudchadkar, R.3
Grippon, S.4
Kirkpatrick, P.5
-
5
-
-
84862859820
-
Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer
-
Suzanne LT, Hodi FS, Julie RB, Scott NG, David CS, David FM, John DP, Richard DC, Jeffrey AS, Michael BA, Philip DL, David RS, Scott JA, et al. Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer. N Engl J Med. 2012; 366.
-
(2012)
N Engl J Med
, pp. 366
-
-
Suzanne, L.T.1
Hodi, F.S.2
Julie, R.B.3
Scott, N.G.4
David, C.S.5
David, F.M.6
John, D.P.7
Richard, D.C.8
Jeffrey, A.S.9
Michael, B.A.10
Philip, D.L.11
David, R.S.12
Scott, J.A.13
-
6
-
-
84962009435
-
Epithelial PD-L2 expression marks Barrett's Esophagus and Esophageal Adenocarcinoma
-
Derks S, Nason KS, Liao X, Stachler MD, Liu KX, Liu JB, Sicinska E, Goldberg MS, Freeman GJ, Rodig SJ, Davison JM, Bass AJ. Epithelial PD-L2 expression marks Barrett's Esophagus and Esophageal Adenocarcinoma. Cancer Immunol Res. 2015.
-
(2015)
Cancer Immunol Res
-
-
Derks, S.1
Nason, K.S.2
Liao, X.3
Stachler, M.D.4
Liu, K.X.5
Liu, J.B.6
Sicinska, E.7
Goldberg, M.S.8
Freeman, G.J.9
Rodig, S.J.10
Davison, J.M.11
Bass, A.J.12
-
7
-
-
79251572651
-
Cutting edge: TIGIT has T cell-intrinsic inhibitory functions
-
Joller N, Hafler JP, Brynedal B, Kassam N, Spoerl S, Levin SD, Sharpe AH, Kuchroo VK. Cutting edge: TIGIT has T cell-intrinsic inhibitory functions. J Immunol. 2011; 186:1338-1342.
-
(2011)
J Immunol
, vol.186
, pp. 1338-1342
-
-
Joller, N.1
Hafler, J.P.2
Brynedal, B.3
Kassam, N.4
Spoerl, S.5
Levin, S.D.6
Sharpe, A.H.7
Kuchroo, V.K.8
-
8
-
-
84860329359
-
The TIGIT/CD226 axis regulates human T cell functio
-
Lozano E, Dominguez-Villar M, Kuchroo V, Hafler D. The TIGIT/CD226 axis regulates human T cell function. J Immunol. (Baltimore, Md: 1950). 2012; 188:3869-3875.
-
(2012)
J Immunol (Baltimore, Md: 1950)
, vol.188
, pp. 3869-3875
-
-
Lozano, E.1
Dominguez-Villar, M.2
Kuchroo, V.3
Hafler, D.4
-
9
-
-
77957723967
-
Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients
-
Fourcade J, Sun Z, Benallaoua M, Guillaume P, Luescher IF, Sander C, Kirkwood JM, Kuchroo V, Zarour HM. Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients. J Exp Med. 2010; 207:2175-2186.
-
(2010)
J Exp Med
, vol.207
, pp. 2175-2186
-
-
Fourcade, J.1
Sun, Z.2
Benallaoua, M.3
Guillaume, P.4
Luescher, I.F.5
Sander, C.6
Kirkwood, J.M.7
Kuchroo, V.8
Zarour, H.M.9
-
10
-
-
79955977180
-
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
-
Zhou Q, Munger M, Veenstra R, Weigel B, Hirashima M, Munn D, Murphy W, Azuma M, Anderson A, Kuchroo V, Blazar B. Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia. Blood. 2011; 117:4501-4510.
-
(2011)
Blood
, vol.117
, pp. 4501-4510
-
-
Zhou, Q.1
Munger, M.2
Veenstra, R.3
Weigel, B.4
Hirashima, M.5
Munn, D.6
Murphy, W.7
Azuma, M.8
Anderson, A.9
Kuchroo, V.10
Blazar, B.11
-
11
-
-
84929000784
-
TIGIT and PD-1 impair tumor antigen-specific CD8(+) T cells in melanoma patients
-
Chauvin JM, Pagliano O, Fourcade J, Sun Z, Wang H, Sander C, Kirkwood JM, Chen TH, Maurer M, Korman AJ, Zarour HM. TIGIT and PD-1 impair tumor antigen-specific CD8(+) T cells in melanoma patients. J Clin Invest. 2015; 125:2046-2058.
-
(2015)
J Clin Invest
, vol.125
, pp. 2046-2058
-
-
Chauvin, J.M.1
Pagliano, O.2
Fourcade, J.3
Sun, Z.4
Wang, H.5
Sander, C.6
Kirkwood, J.M.7
Chen, T.H.8
Maurer, M.9
Korman, A.J.10
Zarour, H.M.11
-
12
-
-
84919494669
-
The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function
-
Johnston RJ, Comps-Agrar L, Hackney J, Yu X, Huseni M, Yang Y, Park S, Javinal V, Chiu H, Irving B, Eaton DL, Grogan JL. The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function. Cancer Cell. 2014; 26:923-937.
-
(2014)
Cancer Cell
, vol.26
, pp. 923-937
-
-
Johnston, R.J.1
Comps-Agrar, L.2
Hackney, J.3
Yu, X.4
Huseni, M.5
Yang, Y.6
Park, S.7
Javinal, V.8
Chiu, H.9
Irving, B.10
Eaton, D.L.11
Grogan, J.L.12
-
13
-
-
84879703551
-
Strength of PD-1 signaling differentially affects T-cell effector functions
-
Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman GJ, Krogsgaard M, Riley JL. Strength of PD-1 signaling differentially affects T-cell effector functions. Proc Natl Acad Sci USA. 2013; 110:E2480-2489.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. E2480-E2489
-
-
Wei, F.1
Zhong, S.2
Ma, Z.3
Kong, H.4
Medvec, A.5
Ahmed, R.6
Freeman, G.J.7
Krogsgaard, M.8
Riley, J.L.9
-
14
-
-
84874635440
-
Tim-3 expression defines regulatory T cells in human tumors
-
Yan J, Zhang Y, Zhang J-P, Liang J, Li L, Zheng L. Tim-3 expression defines regulatory T cells in human tumors. PloS one. 2013; 8.
-
(2013)
PloS one
, pp. 8
-
-
Yan, J.1
Zhang, Y.2
Zhang, J.-P.3
Liang, J.4
Li, L.5
Zheng, L.6
-
15
-
-
84920655625
-
PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients
-
D'Incecco A, Andreozzi M, Ludovini V, Rossi E, Capodanno A, Landi L, Tibaldi C, Minuti G, Salvini J, Coppi E, Chella A, Fontanini G, Filice ME, et al. PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients. Br J Cancer. 2015; 112:95-102.
-
(2015)
Br J Cancer
, vol.112
, pp. 95-102
-
-
D'Incecco, A.1
Andreozzi, M.2
Ludovini, V.3
Rossi, E.4
Capodanno, A.5
Landi, L.6
Tibaldi, C.7
Minuti, G.8
Salvini, J.9
Coppi, E.10
Chella, A.11
Fontanini, G.12
Filice, M.E.13
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