Discovery of a selective islet peptidome presented by the highest-risk HLA-DQ8trans molecule

Diabetes

Volumn 65, Issue 3, 2016, Pages 732-741

  Van Lummel, Menno ^a   Van Veelen, Peter A ^a   De Ru, Arnoud H ^a   Pool, Jos ^a   Nikolic, Tatjana ^a   Laban, Sandra ^a   Joosten, Antoinette ^a   Drijfhout, Jan W ^a   Gómez Touriño, Iria ^b   Arif, Sefina ^b   Aanstoot, Henk J ^c   Peakman, Mark ^b   Roep, Bart O ^a,d  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c Diabeter   (Netherlands)

^d CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLUTAMATE DECARBOXYLASE 65; HLA DQ2 ANTIGEN; HLA DQ8 ANTIGEN; SIGNAL PEPTIDE; AUTOANTIGEN; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 2; HLA DQ ANTIGEN; INSULIN; PEPTIDE; PREPROINSULIN; PROTEIN PRECURSOR; PTPRN PROTEIN, HUMAN; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE;

ADOLESCENT; ANTIGEN BINDING; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; ADULT; CASE CONTROL STUDY; CHILD; FEMALE; GENETICS; HETEROZYGOTE; HOMOZYGOTE; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; PROTEIN PROCESSING; T LYMPHOCYTE; YOUNG ADULT;

ADOLESCENT; ADULT; AUTOANTIGENS; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHILD; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; EPITOPES; FEMALE; GLUTAMATE DECARBOXYLASE; HETEROZYGOTE; HLA-DQ ANTIGENS; HOMOZYGOTE; HUMANS; INSULIN; MALE; PEPTIDES; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 8; T-LYMPHOCYTES; YOUNG ADULT;

EID: 84962406592     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-1031     Document Type: Article

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