-
1
-
-
77950344427
-
Burden of community-acquired pneumonia in North American adults
-
File TM, Jr, Marrie TJ., Burden of community-acquired pneumonia in North American adults. Postgrad Med. 2010;122:130–141.
-
(2010)
Postgrad Med
, vol.122
, pp. 130-141
-
-
File, T.M.1
Marrie, T.J.2
-
2
-
-
84893609243
-
Clinical practice. Community-acquired pneumonia
-
Wunderink RG, Waterer GW. Clinical practice. Community-acquired pneumonia. N Engl J Med. 2014;370(6):543–551.
-
(2014)
N Engl J Med
, vol.370
, Issue.6
, pp. 543-551
-
-
Wunderink, R.G.1
Waterer, G.W.2
-
3
-
-
34547925249
-
CAPNETZ study group approaches to estimate the population-based incidence of community acquired pneumonia
-
Schnoor M, Hedicke J, Dalhoff K, et al. CAPNETZ study group approaches to estimate the population-based incidence of community acquired pneumonia. J Infect. 2007;55(3):233–239.
-
(2007)
J Infect
, vol.55
, Issue.3
, pp. 233-239
-
-
Schnoor, M.1
Hedicke, J.2
Dalhoff, K.3
-
4
-
-
0030031642
-
Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis
-
Fine MJ, Smith MA, Carson CA, et al. Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis. JAMA. 1996;275:134–141.
-
(1996)
JAMA
, vol.275
, pp. 134-141
-
-
Fine, M.J.1
Smith, M.A.2
Carson, C.A.3
-
5
-
-
0035879380
-
Etiology, reasons for hospitalization, risk classes, and outcomes of community-acquired pneumonia in patients hospitalized on the basis of conventional admission criteria
-
Roson B, Carratala J, Dorca J, et al. Etiology, reasons for hospitalization, risk classes, and outcomes of community-acquired pneumonia in patients hospitalized on the basis of conventional admission criteria. Clin Infect Dis. 2001;33:158–165.
-
(2001)
Clin Infect Dis
, vol.33
, pp. 158-165
-
-
Roson, B.1
Carratala, J.2
Dorca, J.3
-
6
-
-
84879996414
-
Severe community-acquired pneumonia
-
Sligl WI, Marrie TJ. Severe community-acquired pneumonia. Crit Care Clin. 2013;29(3):563–601.
-
(2013)
Crit Care Clin
, vol.29
, Issue.3
, pp. 563-601
-
-
Sligl, W.I.1
Marrie, T.J.2
-
7
-
-
84944152654
-
Community-acquired pneumonia: an overview
-
Mandell LA. Community-acquired pneumonia:an overview. Postgrad Med. 2015;127(6):607–615.
-
(2015)
Postgrad Med
, vol.127
, Issue.6
, pp. 607-615
-
-
Mandell, L.A.1
-
8
-
-
33847155159
-
Infectious diseases society of America; American thoracic society. Infectious diseases society of America/American thoracic society consensus guidelines on the management of community-acquired pneumonia in adults
-
Mandell LA, Wunderink RG, Anzueto A, et al. Infectious diseases society of America; American thoracic society. Infectious diseases society of America/American thoracic society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis. 2007;44(Suppl 2):S27–S72.
-
(2007)
Clin Infect Dis
, vol.44
, pp. S27-S72
-
-
Mandell, L.A.1
Wunderink, R.G.2
Anzueto, A.3
-
9
-
-
84878114886
-
Advances in antibiotic therapy for community-acquired pneumonia
-
Viasus D, Garcia-Vidal C, Carratalà J. Advances in antibiotic therapy for community-acquired pneumonia. Curr Opin Pulm Med. 2013;19(3):209–215.
-
(2013)
Curr Opin Pulm Med
, vol.19
, Issue.3
, pp. 209-215
-
-
Viasus, D.1
Garcia-Vidal, C.2
Carratalà, J.3
-
10
-
-
80053284682
-
Joint taskforce of the European respiratory society and European society for clinical microbiology and infectious diseases. Guidelines for the management of adult lower respiratory tract infections
-
Woodhead M, Blasi F, Ewig S, et al. Joint taskforce of the European respiratory society and European society for clinical microbiology and infectious diseases. Guidelines for the management of adult lower respiratory tract infections. Clin Microbiol Infect. 2011;17(Suppl 6):E1–E59.
-
(2011)
Clin Microbiol Infect
, vol.17
, pp. E1-E59
-
-
Woodhead, M.1
Blasi, F.2
Ewig, S.3
-
11
-
-
63249091069
-
The science of selecting antimicrobials for community-acquired pneumonia (CAP)
-
File TM. The science of selecting antimicrobials for community-acquired pneumonia (CAP). J Manag Care Pharm. 2009;15(Suppl 2):S5–S11.
-
(2009)
J Manag Care Pharm
, vol.15
, pp. S5-S11
-
-
File, T.M.1
-
12
-
-
84861374442
-
Clinical evaluation of the role of ceftaroline in the management of community acquired bacterial pneumonia
-
Maselli DJ, Fernandez JF, Whong CY, et al. Clinical evaluation of the role of ceftaroline in the management of community acquired bacterial pneumonia. Infect Drug Resist. 2012;5:43–51.
-
(2012)
Infect Drug Resist
, vol.5
, pp. 43-51
-
-
Maselli, D.J.1
Fernandez, J.F.2
Whong, C.Y.3
-
13
-
-
63149128595
-
Early and late treatment failure in community-acquired pneumonia
-
Garcia-Vidal C, Carratalà J. Early and late treatment failure in community-acquired pneumonia. Semin Respir Crit Care Med. 2009;30(2):154–160.
-
(2009)
Semin Respir Crit Care Med
, vol.30
, Issue.2
, pp. 154-160
-
-
Garcia-Vidal, C.1
Carratalà, J.2
-
14
-
-
77957892620
-
Declining antimicrobial susceptibility of streptococcus pneumoniae in the United States: report from the SENTRY antimicrobial surveillance program
-
Jones RN, Sader HS, Moet GJ, et al. Declining antimicrobial susceptibility of streptococcus pneumoniae in the United States:report from the SENTRY antimicrobial surveillance program. Diagn Microbiol Infect Dis. 2010;68:334–336.
-
(2010)
Diagn Microbiol Infect Dis
, vol.68
, pp. 334-336
-
-
Jones, R.N.1
Sader, H.S.2
Moet, G.J.3
-
15
-
-
84876102732
-
-
Available from, June
-
Antimicrobial resistance surveillance in Europe 2014. European Antimicrobial Resistance Surveillance Network (EARS-Net). [cited 2015 June]. Available from:http://ecdc.europa.eu/en/publications/Publications/antimicrobial-resistance-europe-2014.pdf
-
(2014)
European Antimicrobial Resistance Surveillance Network (EARS-Net)
-
-
-
16
-
-
85006705736
-
Fluoroquinolone-nonsusceptible Streptococcus pneumoniae isolates from a medical center in the pneumococcal conjugate vaccine era
-
Chen HH, Li HC, Su LH, et al. Fluoroquinolone-nonsusceptible Streptococcus pneumoniae isolates from a medical center in the pneumococcal conjugate vaccine era. J Microbiol Immunol Infect. 2016;pii:S1684-1182(16)30044-5. DOI:10.1016/j.jmii.2016.05.003
-
(2016)
J Microbiol Immunol Infect
-
-
Chen, H.H.1
Li, H.C.2
Su, L.H.3
-
17
-
-
84865210377
-
AWARE ceftaroline surveillance program (2008-2010): trends in resistance patterns among Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States
-
Pfaller MA, Farrell DJ, Sader HS, et al. AWARE ceftaroline surveillance program (2008-2010):trends in resistance patterns among Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States. Clin Infect Dis. 2012;55(Suppl 3):S187–S193.
-
(2012)
Clin Infect Dis
, vol.55
, pp. S187-S193
-
-
Pfaller, M.A.1
Farrell, D.J.2
Sader, H.S.3
-
18
-
-
54349102795
-
BSAC working parties on resistance surveillance. Nonsusceptibility trends among Haemophilus influenzae and Moraxella catarrhalis from community-acquired respiratory tract infections in the UK and Ireland 1999-2007
-
Morrissey I, Maher K, Williams L, et al. BSAC working parties on resistance surveillance. Nonsusceptibility trends among Haemophilus influenzae and Moraxella catarrhalis from community-acquired respiratory tract infections in the UK and Ireland 1999-2007. J Antimicrob Chemother. 2008;62(Suppl2):ii97–ii103.
-
(2008)
J Antimicrob Chemother
, vol.62
, pp. ii97-ii103
-
-
Morrissey, I.1
Maher, K.2
Williams, L.3
-
19
-
-
77952243582
-
Macrolide-resistant Mycoplasma pneumoniae: characteristics of isolates and clinical aspects of community acquired pneumonia
-
Morozumi M, Takahashi T, Ubukata K. Macrolide-resistant Mycoplasma pneumoniae:characteristics of isolates and clinical aspects of community acquired pneumonia. J Infect Chemother. 2010;16:78–86.
-
(2010)
J Infect Chemother
, vol.16
, pp. 78-86
-
-
Morozumi, M.1
Takahashi, T.2
Ubukata, K.3
-
20
-
-
79955606245
-
Mycoplasma pneumoniae: susceptibility and resistance to antibiotics
-
Bebear CM, Pereyre S, Peuchant O. Mycoplasma pneumoniae:susceptibility and resistance to antibiotics. Future Microbiol. 2011;6:423–431.
-
(2011)
Future Microbiol
, vol.6
, pp. 423-431
-
-
Bebear, C.M.1
Pereyre, S.2
Peuchant, O.3
-
21
-
-
84862077230
-
Macrolide resistance determination and molecular typing of Mycoplasma pneumoniae in respiratory specimens collected between 1997 and 2008 in The Netherlands
-
Spuesens EB, Meijer A, Bierschenk D, et al. Macrolide resistance determination and molecular typing of Mycoplasma pneumoniae in respiratory specimens collected between 1997 and 2008 in The Netherlands. J Clin Microbiol. 2012;50:1999–2004.
-
(2012)
J Clin Microbiol
, vol.50
, pp. 1999-2004
-
-
Spuesens, E.B.1
Meijer, A.2
Bierschenk, D.3
-
22
-
-
85122837317
-
No detection of macrolide-resistant Mycoplasma pneumoniae from Swedish patients, 1996-2013
-
Gullsby K, Bondeson K. No detection of macrolide-resistant Mycoplasma pneumoniae from Swedish patients, 1996-2013. Infect Ecol Epidemiol. 2016;6:31374.
-
(2016)
Infect Ecol Epidemiol
, vol.6
, pp. 31374
-
-
Gullsby, K.1
Bondeson, K.2
-
23
-
-
84907050377
-
The wobbly status of ketolides: where do we stand?
-
Georgopapadakou NH. The wobbly status of ketolides:where do we stand? Expert Opin Investig Drugs. 2014;23(10):1313–1319.
-
(2014)
Expert Opin Investig Drugs
, vol.23
, Issue.10
, pp. 1313-1319
-
-
Georgopapadakou, N.H.1
-
24
-
-
78649681337
-
Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis
-
Llano-Sotelo B, Dunkle J, Klepacki D, et al. Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis. Antimicrob Agents Chemother. 2010;54(12):4961–4970.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.12
, pp. 4961-4970
-
-
Llano-Sotelo, B.1
Dunkle, J.2
Klepacki, D.3
-
25
-
-
84875188301
-
Solithromycin inhibition of protein synthesis and ribosome biogenesis in Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae
-
Rodgers W[, Frazier AD, Champney WS. Solithromycin inhibition of protein synthesis and ribosome biogenesis in Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae. Antimicrob Agents Chemother. 2013;57(4):1632–1637.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, Issue.4
, pp. 1632-1637
-
-
Rodgers, W.1
Frazier, A.D.2
Champney, W.S.3
-
26
-
-
84973667566
-
Results from the solithromycin international surveillance program (2014)
-
Farrell DJ, Flamm RK, Sader HS, et al. Results from the solithromycin international surveillance program (2014). Antimicrob Agents Chemother. 2016;60(6):3662–3668.
-
(2016)
Antimicrob Agents Chemother
, vol.60
, Issue.6
, pp. 3662-3668
-
-
Farrell, D.J.1
Flamm, R.K.2
Sader, H.S.3
-
27
-
-
77951769604
-
Antimicrobial characterisation of CEM-101 activity against respiratory tract pathogens, including multidrug-resistant pneumococcal serogroup 19A isolates
-
Farrell DJ, Sader HS, Castanheira M, et al. Antimicrobial characterisation of CEM-101 activity against respiratory tract pathogens, including multidrug-resistant pneumococcal serogroup 19A isolates. Int J Antimicrob Agents. 2010;35(6):537–543.
-
(2010)
Int J Antimicrob Agents
, vol.35
, Issue.6
, pp. 537-543
-
-
Farrell, D.J.1
Sader, H.S.2
Castanheira, M.3
-
28
-
-
66149134798
-
Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101
-
Waites KB, Crabb DM, Duffy LB. Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101. Antimicrob Agents Chemother. 2009;53(5):2139–2141.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, Issue.5
, pp. 2139-2141
-
-
Waites, K.B.1
Crabb, D.M.2
Duffy, L.B.3
-
29
-
-
84893468460
-
Antimicrobial activity of solithromycin against clinical isolates of Legionella pneumophila serogroup 1
-
Mallegol J, Fernandes P, Melano RG, et al. Antimicrobial activity of solithromycin against clinical isolates of Legionella pneumophila serogroup 1. Antimicrob Agents Chemother. 2014;58(2):909–915.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.2
, pp. 909-915
-
-
Mallegol, J.1
Fernandes, P.2
Melano, R.G.3
-
30
-
-
84879191168
-
Correlation of MIC value and disk inhibition zone diameters in clinical Legionella pneumophila serogroup 1 isolates
-
Bruin JP, Diederen BM, Ijzerman EP, et al. Correlation of MIC value and disk inhibition zone diameters in clinical Legionella pneumophila serogroup 1 isolates. Diagn Microbiol Infect Dis. 2013;76:339–342.
-
(2013)
Diagn Microbiol Infect Dis
, vol.76
, pp. 339-342
-
-
Bruin, J.P.1
Diederen, B.M.2
Ijzerman, E.P.3
-
31
-
-
78650276690
-
Antimicrobial characterisation of solithromycin (CEM-101), a novel fluoroketolide: activity against staphylococci and enterococci
-
Putnam SD, Sader HS, Farrell DJ, et al. Antimicrobial characterisation of solithromycin (CEM-101), a novel fluoroketolide:activity against staphylococci and enterococci. Int J Antimicrob Agents. 2011;37(1):39–45.
-
(2011)
Int J Antimicrob Agents
, vol.37
, Issue.1
, pp. 39-45
-
-
Putnam, S.D.1
Sader, H.S.2
Farrell, D.J.3
-
32
-
-
84997327902
-
The solithromycin journey-It is all in the chemistry
-
[Epub ahead of print]
-
Fernandes P, Martens E, Bertrand D, et al. The solithromycin journey-It is all in the chemistry. Bioorg Med Chem. 2016; pii:S0968-0896(16)30642-3. [Epub ahead of print].
-
(2016)
Bioorg Med Chem
-
-
Fernandes, P.1
Martens, E.2
Bertrand, D.3
-
33
-
-
79955542813
-
Pharmacokinetics of solithromycin (CEM-101) after single or multiple oral doses and effects of food on single-dose bioavailability in healthy adult subjects
-
Still JG, Schranz J, Degenhardt TP, et al. Pharmacokinetics of solithromycin (CEM-101) after single or multiple oral doses and effects of food on single-dose bioavailability in healthy adult subjects. Antimicrob Agents Chemother. 2011;55(5):1997–2003.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.5
, pp. 1997-2003
-
-
Still, J.G.1
Schranz, J.2
Degenhardt, T.P.3
-
34
-
-
85006469593
-
-
Available from, June
-
Schranz J, Clark K, Marion A, et al. [cited 2016 June]. Available from:http://www.cempra.com/common/pdf/abstracts/ECCMID%202011_Schranz_Solithromycin%20Phase%20I%20IV_Abstract%20095.pdf
-
-
-
Schranz, J.1
Clark, K.2
Marion, A.3
-
35
-
-
84866337951
-
Comparison of plasma, epithelial lining fluid, and alveolar macrophage concentrations of solithromycin (CEM-101) in healthy adult subjects
-
Rodvold KA, Gotfried MH, Still JG, et al. Comparison of plasma, epithelial lining fluid, and alveolar macrophage concentrations of solithromycin (CEM-101) in healthy adult subjects. Antimicrob Agents Chemother. 2012;56(10):5076–5081.• Excellent study outlining the concentrations of solithromycin in epithelial lining fluid and alveolar macrophages.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.10
, pp. 5076-5081
-
-
Rodvold, K.A.1
Gotfried, M.H.2
Still, J.G.3
-
36
-
-
84939865011
-
Safety and pharmacokinetics of solithromycin in subjects with hepatic impairment
-
Jamieson BD, Ciric S, Fernandes P. Safety and pharmacokinetics of solithromycin in subjects with hepatic impairment. Antimicrob Agents Chemother. 2015;59(8):4379–4386.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.8
, pp. 4379-4386
-
-
Jamieson, B.D.1
Ciric, S.2
Fernandes, P.3
-
37
-
-
84922325634
-
Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta
-
Keelan JA, Pugazhenthi K. Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta. Placenta. 2014;35(12):1043–1048.
-
(2014)
Placenta
, vol.35
, Issue.12
, pp. 1043-1048
-
-
Keelan, J.A.1
Pugazhenthi, K.2
-
38
-
-
84891524394
-
Maternal administration of solithromycin, a new, potent, broad-spectrum fluoroketolide antibiotic, achieves fetal and intra-amniotic antimicrobial protection in a pregnant sheep model
-
Keelan JA, Kemp MW, Payne MS, et al. Maternal administration of solithromycin, a new, potent, broad-spectrum fluoroketolide antibiotic, achieves fetal and intra-amniotic antimicrobial protection in a pregnant sheep model. Antimicrob Agents Chemother. 2014;58(1):447–454.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.1
, pp. 447-454
-
-
Keelan, J.A.1
Kemp, M.W.2
Payne, M.S.3
-
39
-
-
84958884211
-
The role of solithromycin in the management of bacterial community-acquired pneumonia
-
Van Bambeke F, Tulkens PM. The role of solithromycin in the management of bacterial community-acquired pneumonia. Expert Rev Anti Infect Ther. 2016;14(3):311–324.
-
(2016)
Expert Rev Anti Infect Ther
, vol.14
, Issue.3
, pp. 311-324
-
-
Van Bambeke, F.1
Tulkens, P.M.2
-
43
-
-
84875413952
-
A novel macrolide solithromycin exerts superior anti-inflammatory effect via NF-κB inhibition
-
Kobayashi Y, Wada H, Rossios C, et al. A novel macrolide solithromycin exerts superior anti-inflammatory effect via NF-κB inhibition. J Pharmacol Exp Ther. 2013;345(1):76–84.
-
(2013)
J Pharmacol Exp Ther
, vol.345
, Issue.1
, pp. 76-84
-
-
Kobayashi, Y.1
Wada, H.2
Rossios, C.3
-
45
-
-
84877846455
-
Randomized, double-blind, multicenter phase 2 study comparing the efficacy and safety of oral solithromycin (CEM-101) to those of oral levofloxacin in the treatment of patients with community-acquired bacterial pneumonia
-
Oldach D, Clark K, Schranz J, et al. Randomized, double-blind, multicenter phase 2 study comparing the efficacy and safety of oral solithromycin (CEM-101) to those of oral levofloxacin in the treatment of patients with community-acquired bacterial pneumonia. Antimicrob Agents Chemother. 2013;57(6):2526–2534.• First trial to suggest the efficacy of solithromycin therapy in patients with CABP.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, Issue.6
, pp. 2526-2534
-
-
Oldach, D.1
Clark, K.2
Schranz, J.3
-
46
-
-
84961396906
-
Efficacy and safety of oral solithromycin versus oral moxifloxacin for treatment of community-acquired bacterial pneumonia: a global, double-blind, multicentre, randomised, active-controlled, non-inferiority trial (SOLITAIRE-ORAL)
-
Barrera CM, Mykietiuk A, Metev H, et al.; SOLITAIRE-ORAL Pneumonia Team. Efficacy and safety of oral solithromycin versus oral moxifloxacin for treatment of community-acquired bacterial pneumonia:a global, double-blind, multicentre, randomised, active-controlled, non-inferiority trial (SOLITAIRE-ORAL). Lancet Infect Dis. 2016; 16(4):421–430.• Large randomized control trial demonstrating the clinical efficacy of oral solithromycin in the management of patients with CABP.
-
(2016)
Lancet Infect Dis
, vol.16
, Issue.4
, pp. 421-430
-
-
Barrera, C.M.1
Mykietiuk, A.2
Metev, H.3
-
47
-
-
84990888176
-
-
File TM, Jr, Rewerska B, Vucinić-Mihailović V, et al.; SOLITAIRE-IV Pneumonia Team. SOLITAIRE-IV:a randomized, double-blind, multicenter study comparing the efficacy and safety of intravenous-to-oral solithromycin to intravenous-to-oral moxifloxacin for treatment of community-acquired bacterial pneumonia. Clin Infect Dis. 2016;63(8):1007–1016.• Large randomized control trial demonstrating the clinical efficacy of intravenous solithromycin in the management of patients with CABP.
-
(2016)
SOLITAIRE-IV: a randomized, double-blind, multicenter study comparing the efficacy and safety of intravenous-to-oral solithromycin to intravenous-to-oral moxifloxacin for treatment of community-acquired bacterial pneumonia
, vol.63
, Issue.8
, pp. 1007-1016
-
-
File, T.M.1
Rewerska, B.2
Vucinić-Mihailović, V.3
-
48
-
-
84878893147
-
Current treatment of community-acquired pneumonia
-
Liapikou A, Torres A. Current treatment of community-acquired pneumonia. Expert Opin Pharmacother. 2013;14(10):1319–1332.
-
(2013)
Expert Opin Pharmacother
, vol.14
, Issue.10
, pp. 1319-1332
-
-
Liapikou, A.1
Torres, A.2
-
49
-
-
84876129813
-
Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies
-
Schembri S, Williamson PA, Short PM, et al. Cardiovascular events after clarithromycin use in lower respiratory tract infections:analysis of two prospective cohort studies. BMJ. 2013;346:f1235.
-
(2013)
BMJ
, vol.346
, pp. f1235
-
-
Schembri, S.1
Williamson, P.A.2
Short, P.M.3
|