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Volumn 35, Issue 6, 2010, Pages 537-543

Antimicrobial characterisation of CEM-101 activity against respiratory tract pathogens, including multidrug-resistant pneumococcal serogroup 19A isolates

Author keywords

Antimicrobial resistance; CEM 101; Community acquired bacterial pneumonia; Ketolide; Streptococcus pneumoniae

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; ANTIINFECTIVE AGENT; AZITHROMYCIN; BETA LACTAMASE; CEFDINIR; CEM 101; CIPROFLOXACIN; CLARITHROMYCIN; CLINDAMYCIN; COTRIMOXAZOLE; DALFOPRISTIN PLUS QUINUPRISTIN; ERYTHROMYCIN; KETOLIDE; LEVOFLOXACIN; LINCOSAMIDE; MACROLIDE; MIKAMYCIN B; RIFAMPICIN; TELITHROMYCIN; TETRACYCLINE; UNCLASSIFIED DRUG;

EID: 77951769604     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2010.01.026     Document Type: Article
Times cited : (48)

References (37)
  • 1
    • 77951769051 scopus 로고    scopus 로고
    • World Health Organization. Acute respiratory infections (update September 2009). Geneva, Switzerland, WHO. [accessed 10 February 2010].
    • World Health Organization. Acute respiratory infections (update September 2009). Geneva, Switzerland, WHO. [accessed 10 February 2010]. http://www.who.int/vaccine_research/diseases/ari/en/index.html.
  • 2
    • 0033767882 scopus 로고    scopus 로고
    • The epidemiology of respiratory tract infections
    • File T.M. The epidemiology of respiratory tract infections. Semin Respir Infect 2000, 15:184-194.
    • (2000) Semin Respir Infect , vol.15 , pp. 184-194
    • File, T.M.1
  • 3
    • 58149218489 scopus 로고    scopus 로고
    • Is activity against 'atypical' pathogens necessary in the treatment protocols for community-acquired pneumonia? Issues with combination therapy
    • Bartlett J.G. Is activity against 'atypical' pathogens necessary in the treatment protocols for community-acquired pneumonia? Issues with combination therapy. Clin Infect Dis 2008, 47(Suppl. 3):S232-S236.
    • (2008) Clin Infect Dis , vol.47 , Issue.SUPPL. 3
    • Bartlett, J.G.1
  • 4
    • 33847155159 scopus 로고    scopus 로고
    • Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults
    • Mandell L.A., Wunderink R.G., Anzueto A., Bartlett J.G., Campbell G.D., Dean N.C., et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007, 44(Suppl. 2):S27-S72.
    • (2007) Clin Infect Dis , vol.44 , Issue.SUPPL. 2
    • Mandell, L.A.1    Wunderink, R.G.2    Anzueto, A.3    Bartlett, J.G.4    Campbell, G.D.5    Dean, N.C.6
  • 5
    • 0011561048 scopus 로고    scopus 로고
    • The Alexander Project 1996-1997: latest susceptibility data from this international study of bacterial pathogens from community-acquired lower respiratory tract infections
    • Alexander Project Group
    • Felmingham D., Grüneberg R.N. The Alexander Project 1996-1997: latest susceptibility data from this international study of bacterial pathogens from community-acquired lower respiratory tract infections. J Antimicrob Chemother 2000, 45:191-203. Alexander Project Group.
    • (2000) J Antimicrob Chemother , vol.45 , pp. 191-203
    • Felmingham, D.1    Grüneberg, R.N.2
  • 6
    • 0036732817 scopus 로고    scopus 로고
    • The PROTEKT surveillance study: antimicrobial susceptibility of Haemophilus influenzae and Moraxella catarrhalis from community-acquired respiratory tract infections
    • Hoban D., Felmingham D. The PROTEKT surveillance study: antimicrobial susceptibility of Haemophilus influenzae and Moraxella catarrhalis from community-acquired respiratory tract infections. J Antimicrob Chemother 2002, 50(Suppl. S1):49-59.
    • (2002) J Antimicrob Chemother , vol.50 , Issue.SUPPL. S1 , pp. 49-59
    • Hoban, D.1    Felmingham, D.2
  • 7
    • 0041736229 scopus 로고    scopus 로고
    • Worldwide trends in antimicrobial resistance among common respiratory tract pathogens in children
    • Jacobs M.R. Worldwide trends in antimicrobial resistance among common respiratory tract pathogens in children. Pediatr Infect Dis J 2003, 22(8 Suppl.):S109-S119.
    • (2003) Pediatr Infect Dis J , vol.22 , Issue.8 SUPPL.
    • Jacobs, M.R.1
  • 9
    • 84944656315 scopus 로고
    • Emergence of drug-resistant pneumococcal infections in the United States
    • Breiman R.F., Butler J.C., Tenover F.C., Elliott J.A., Facklam R.R. Emergence of drug-resistant pneumococcal infections in the United States. JAMA 1994, 271:1831-1835.
    • (1994) JAMA , vol.271 , pp. 1831-1835
    • Breiman, R.F.1    Butler, J.C.2    Tenover, F.C.3    Elliott, J.A.4    Facklam, R.R.5
  • 10
    • 0030003732 scopus 로고    scopus 로고
    • Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: results of a 30-center national surveillance study
    • Doern G.V., Brueggemann A., Holley H.P., Rauch A.M. Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: results of a 30-center national surveillance study. Antimicrob Agents Chemother 1996, 40:1208-1213.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1208-1213
    • Doern, G.V.1    Brueggemann, A.2    Holley, H.P.3    Rauch, A.M.4
  • 11
    • 0242684416 scopus 로고    scopus 로고
    • Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine
    • Whitney C.G., Farley M.M., Hadler J., Harrison L.H., Bennett N.M., Lynfield R., et al. Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine. N Engl J Med 2003, 348:1737-1746.
    • (2003) N Engl J Med , vol.348 , pp. 1737-1746
    • Whitney, C.G.1    Farley, M.M.2    Hadler, J.3    Harrison, L.H.4    Bennett, N.M.5    Lynfield, R.6
  • 12
    • 1242291834 scopus 로고    scopus 로고
    • Molecular epidemiology of multiresistant Streptococcus pneumoniae with both erm(B)- and mef(A)-mediated macrolide resistance
    • Farrell D.J., Morrissey I., Bakker S., Morris L., Buckridge S., Felmingham D. Molecular epidemiology of multiresistant Streptococcus pneumoniae with both erm(B)- and mef(A)-mediated macrolide resistance. J Clin Microbiol 2004, 42:764-768.
    • (2004) J Clin Microbiol , vol.42 , pp. 764-768
    • Farrell, D.J.1    Morrissey, I.2    Bakker, S.3    Morris, L.4    Buckridge, S.5    Felmingham, D.6
  • 13
    • 34249813721 scopus 로고    scopus 로고
    • Emergence of 19A as virulent and multidrug resistant pneumococcus in Massachusetts following universal immunization of infants with pneumococcal conjugate vaccine
    • Pelton S.I., Huot H., Finkelstein J.A., Bishop C.J., Hsu K.K., Kellenberg J., et al. Emergence of 19A as virulent and multidrug resistant pneumococcus in Massachusetts following universal immunization of infants with pneumococcal conjugate vaccine. Pediatr Infect Dis J 2007, 26:468-472.
    • (2007) Pediatr Infect Dis J , vol.26 , pp. 468-472
    • Pelton, S.I.1    Huot, H.2    Finkelstein, J.A.3    Bishop, C.J.4    Hsu, K.K.5    Kellenberg, J.6
  • 14
    • 33846647401 scopus 로고    scopus 로고
    • Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States
    • Farrell D.J., Klugman K.P., Pichichero M. Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States. Pediatr Infect Dis J 2007, 26:123-128.
    • (2007) Pediatr Infect Dis J , vol.26 , pp. 123-128
    • Farrell, D.J.1    Klugman, K.P.2    Pichichero, M.3
  • 15
    • 65449179542 scopus 로고    scopus 로고
    • Impact of pneumococcal conjugate vaccine on infections caused by antibiotic-resistant Streptococcus pneumoniae
    • Dagan R. Impact of pneumococcal conjugate vaccine on infections caused by antibiotic-resistant Streptococcus pneumoniae. Clin Microbiol Infect 2009, 15(Suppl. 3):16-20.
    • (2009) Clin Microbiol Infect , vol.15 , Issue.SUPPL. 3 , pp. 16-20
    • Dagan, R.1
  • 16
    • 68049093117 scopus 로고    scopus 로고
    • Increase in pneumococcus macrolide resistance, United States
    • Jenkins S.G., Farrell D.J. Increase in pneumococcus macrolide resistance, United States. Emerg Infect Dis 2009, 15:1260-1264.
    • (2009) Emerg Infect Dis , vol.15 , pp. 1260-1264
    • Jenkins, S.G.1    Farrell, D.J.2
  • 17
    • 0034727809 scopus 로고    scopus 로고
    • Increasing prevalence of multidrug-resistant Streptococcus pneumoniae in the United States
    • Whitney C.G., Farley M.M., Hadler J., Harrison L.H., Lexau C., Reingold A., et al. Increasing prevalence of multidrug-resistant Streptococcus pneumoniae in the United States. N Engl J Med 2000, 343:1917-1924.
    • (2000) N Engl J Med , vol.343 , pp. 1917-1924
    • Whitney, C.G.1    Farley, M.M.2    Hadler, J.3    Harrison, L.H.4    Lexau, C.5    Reingold, A.6
  • 18
    • 33746608911 scopus 로고    scopus 로고
    • Macrolide resistance in bacteremic pneumococcal disease: implications for patient management
    • Toronto Invasive Bacterial Diseases Network
    • Daneman N., McGeer A., Green K., Low D.E. Macrolide resistance in bacteremic pneumococcal disease: implications for patient management. Clin Infect Dis 2006, 43:432-438. Toronto Invasive Bacterial Diseases Network.
    • (2006) Clin Infect Dis , vol.43 , pp. 432-438
    • Daneman, N.1    McGeer, A.2    Green, K.3    Low, D.E.4
  • 19
    • 0037342872 scopus 로고    scopus 로고
    • Drugs of the 21st century: telithromycin (HMR 3647)-the first ketolide
    • Ackermann G., Rodloff A.C. Drugs of the 21st century: telithromycin (HMR 3647)-the first ketolide. J Antimicrob Chemother 2003, 51:497-511.
    • (2003) J Antimicrob Chemother , vol.51 , pp. 497-511
    • Ackermann, G.1    Rodloff, A.C.2
  • 20
    • 33847400958 scopus 로고    scopus 로고
    • Cethromycin: A-195773, A-195773-0, A-1957730, Abbott-195773, ABT 773. Drugs RD
    • Drugs RD. Cethromycin: A-195773, A-195773-0, A-1957730, Abbott-195773, ABT 773. Drugs RD 2007; 8:95-102.
    • (2007) , vol.8 , pp. 95-102
    • Drugs, R.D.1
  • 21
    • 60649121348 scopus 로고    scopus 로고
    • In vitro activity of the investigational ketolide cethromycin against macrolide- and penicillin-resistant Streptococcus pneumoniae: review of the 1998 to 2006 Canadian Respiratory Organism Susceptibility Study (CROSS)
    • Wierzbowski A.K., Karlowsky J.A., Hoban D.J., Zhanel G.G. In vitro activity of the investigational ketolide cethromycin against macrolide- and penicillin-resistant Streptococcus pneumoniae: review of the 1998 to 2006 Canadian Respiratory Organism Susceptibility Study (CROSS). J Antimicrob Chemother 2009, 63:620-622.
    • (2009) J Antimicrob Chemother , vol.63 , pp. 620-622
    • Wierzbowski, A.K.1    Karlowsky, J.A.2    Hoban, D.J.3    Zhanel, G.G.4
  • 25
    • 70349153036 scopus 로고    scopus 로고
    • Cellular accumulation and pharmacodynamic evaluation of the intracellular activity of CEM-101, a novel fluoroketolide, towards Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila in human THP-1 macrophages
    • Lemaire S., Van Bambeke F., Tulkens P.M. Cellular accumulation and pharmacodynamic evaluation of the intracellular activity of CEM-101, a novel fluoroketolide, towards Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila in human THP-1 macrophages. Antimicrob Agents Chemother 2009, 53:3734-3743.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 3734-3743
    • Lemaire, S.1    Van Bambeke, F.2    Tulkens, P.M.3
  • 26
    • 66149134798 scopus 로고    scopus 로고
    • Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101
    • Waites K.B., Crabb D.M., Duffy L.B. Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101. Antimicrob Agents Chemother 2009, 53:2139-2141.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 2139-2141
    • Waites, K.B.1    Crabb, D.M.2    Duffy, L.B.3
  • 27
    • 77951767816 scopus 로고    scopus 로고
    • Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard. 8th ed. Document M7-A8. Wayne, PA: CLSI;.
    • Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard. 8th ed. Document M7-A8. Wayne, PA: CLSI; 2009.
    • (2009)
  • 28
    • 77951766758 scopus 로고    scopus 로고
    • Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. Nineteenth informational supplement. Document M100-S19. Wayne, PA: CLSI; 2009.
    • Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. Nineteenth informational supplement. Document M100-S19. Wayne, PA: CLSI; 2009.
    • (2009)
  • 29
    • 0030736286 scopus 로고    scopus 로고
    • Anti-Legionella activity of trovafloxacin compared with seven other antimicrobial agents including an intermethod evaluation
    • Marco F., Biedenbach D.J., Jones R.N. Anti-Legionella activity of trovafloxacin compared with seven other antimicrobial agents including an intermethod evaluation. Diagn Microbiol Infect Dis 1997, 28:55-57.
    • (1997) Diagn Microbiol Infect Dis , vol.28 , pp. 55-57
    • Marco, F.1    Biedenbach, D.J.2    Jones, R.N.3
  • 30
    • 68649089313 scopus 로고    scopus 로고
    • Emerging macrolide resistance in Mycoplasma pneumoniae in children: detection and characterization of resistant isolates
    • Li X., Atkinson T.P., Hagood J., Makris C., Duffy L.B., Waites K.B. Emerging macrolide resistance in Mycoplasma pneumoniae in children: detection and characterization of resistant isolates. Pediatr Infect Dis J 2009, 28:693-696.
    • (2009) Pediatr Infect Dis J , vol.28 , pp. 693-696
    • Li, X.1    Atkinson, T.P.2    Hagood, J.3    Makris, C.4    Duffy, L.B.5    Waites, K.B.6
  • 31
    • 65649108113 scopus 로고    scopus 로고
    • Emergence of community-acquired meticillin-resistant Staphylococcus aureus strain USA300 as a cause of necrotising community-onset pneumonia
    • Hidron A.I., Low C.E., Honig E.G., Blumberg H.M. Emergence of community-acquired meticillin-resistant Staphylococcus aureus strain USA300 as a cause of necrotising community-onset pneumonia. Lancet Infect Dis 2009, 9:384-392.
    • (2009) Lancet Infect Dis , vol.9 , pp. 384-392
    • Hidron, A.I.1    Low, C.E.2    Honig, E.G.3    Blumberg, H.M.4
  • 32
    • 36749072042 scopus 로고    scopus 로고
    • National and regional assessment of antimicrobial resistance among community-acquired respiratory tract pathogens identified in a 2005-2006 U.S. faropenem surveillance study
    • Critchley I.A., Brown S.D., Traczewski M.M., Tillotson G.S., Janjic N. National and regional assessment of antimicrobial resistance among community-acquired respiratory tract pathogens identified in a 2005-2006 U.S. faropenem surveillance study. Antimicrob Agents Chemother 2007, 51:4382-4389.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 4382-4389
    • Critchley, I.A.1    Brown, S.D.2    Traczewski, M.M.3    Tillotson, G.S.4    Janjic, N.5
  • 33
    • 0037083024 scopus 로고    scopus 로고
    • Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications
    • Leclercq R. Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications. Clin Infect Dis 2002, 34:482-492.
    • (2002) Clin Infect Dis , vol.34 , pp. 482-492
    • Leclercq, R.1
  • 34
    • 4744344340 scopus 로고    scopus 로고
    • An examination of the differential sensitivity to ketolide antibiotics in ermB strains of Streptococcus pyogenes and Streptococcus pneumoniae
    • Champney W.S., Mentens N., Zurawick K. An examination of the differential sensitivity to ketolide antibiotics in ermB strains of Streptococcus pyogenes and Streptococcus pneumoniae. Curr Microbiol 2004, 49:239-247.
    • (2004) Curr Microbiol , vol.49 , pp. 239-247
    • Champney, W.S.1    Mentens, N.2    Zurawick, K.3
  • 35
    • 31944442179 scopus 로고    scopus 로고
    • Streptococcus pyogenes isolates with high-level macrolide resistance and reduced susceptibility to telithromycin associated with 23S rRNA mutations
    • Farrell D.J., Shackcloth J., Barbadora K.A., Green M.D. Streptococcus pyogenes isolates with high-level macrolide resistance and reduced susceptibility to telithromycin associated with 23S rRNA mutations. Antimicrob Agents Chemother 2006, 50:817-818.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 817-818
    • Farrell, D.J.1    Shackcloth, J.2    Barbadora, K.A.3    Green, M.D.4


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