HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant

Gastroenterology

Volumn 151, Issue 5, 2016, Pages 986-998.e4

  Mason, William S ^a   Gill, Upkar S ^b   Litwin, Samuel ^a   Zhou, Yan ^a   Peri, Suraj ^a   Pop, Oltin ^c   Hong, Michelle L W ^d   Naik, Sandhia ^e   Quaglia, Alberto ^c   Bertoletti, Antonio ^d   Kennedy, Patrick T F ^b  

^a FOX CHASE CANCER CENTER   (United States)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

^d DUKE NUS MEDICAL SCHOOL   (Singapore)

^e ROYAL LONDON HOSPITAL   (United Kingdom)

Author keywords

Antiviral Immunity; HBsAg; HBV Replication; Hepatocyte Proliferation

Indexed keywords

HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; BIOLOGICAL MARKER; VIRUS DNA;

ADOLESCENT; ADULT; ANTIGEN EXPRESSION; ARTICLE; BLOOD SAMPLING; CELL EXPANSION; CELLULAR IMMUNITY; CHROMOSOME; CHRONIC HEPATITIS B; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE COURSE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOLOGICAL TOLERANCE; INVERSE POLYMERASE CHAIN REACTION; LIVER CELL; MALE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; T LYMPHOCYTE; TURNOVER TIME; VIRUS DNA CELL DNA INTERACTION; YOUNG ADULT; CASE CONTROL STUDY; GENETICS; HEPATITIS B VIRUS; IMMUNOLOGY; METABOLISM; STATISTICAL ANALYSIS; VIROLOGY;

ADOLESCENT; ADULT; BIOMARKERS; CASE-CONTROL STUDIES; DNA, VIRAL; FEMALE; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HEPATOCYTES; HUMANS; IMMUNE TOLERANCE; MALE; MATCHED-PAIR ANALYSIS; VIRUS INTEGRATION; YOUNG ADULT;

EID: 84992434024     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2016.07.012     Document Type: Article

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