Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial-mesenchymal transition

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 43, 2016, Pages 12238-12243

  Zhao, Siming ^a   Bellone, Stefania ^a   Lopez, Salvatore ^a   Thakral, Durga ^a   Schwab, Carlton ^a   English, Diana P ^a   Black, Jonathan ^a   Cocco, Emiliano ^a   Choi, Jungmin ^a   Zammataro, Luca ^a   Predolini, Federica ^a   Bonazzoli, Elena ^a   Bi, Mark ^a   Buza, Natalia ^a   Hui, Pei ^a   Wong, Serena ^a   Abu Khalaf, Maysa ^a   Ravaggi, Antonella ^b   Bignotti, Eliana ^b   Bandiera, Elisabetta ^b   Romani, Chiara ^b   Todeschini, Paola ^b   Tassi, Renata ^b   Zanotti, Laura ^b   Odicino, Franco ^b   Pecorelli, Sergio ^b   Donzelli, Carla ^b   Ardighieri, Laura ^b   Facchetti, Fabio ^b   Falchetti, Marcella ^b   Silasi, Dan Arin ^a   Ratner, Elena ^a   Azodi, Masoud ^a   Schwartz, Peter E ^a   Mane, Shrikant ^a   Angioli, Roberto ^c   Terranova, Corrado ^c   Quick, Charles Matthew ^d   Edraki, Babak ^e   Bilgüvar, Kaya ^a   Lee, Moses ^f   Choi, Murim ^f   Stiegler, Amy L ^a   Boggon, Titus J ^a   Schlessinger, Joseph ^a   Lifton, Richard P ^a,g   Santin, Alessandro D ^a   more..

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BRESCIA   (Italy)

^c UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^e John Muir Health   (United States)

^f Seoul National University   (South Korea)

^g ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Exome sequencing; Ovarian carcinosarcoma; Uterine carcinosarcoma

Indexed keywords

HISTONE H2A; HISTONE H2B; K RAS PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; DNA BINDING PROTEIN; HISTONE; MBD3 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PIK3CA PROTEIN, HUMAN; PTEN PROTEIN, HUMAN; TELOMERASE; TERT PROTEIN, HUMAN; TP53 PROTEIN, HUMAN;

BCOR GENE; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SURVIVAL; CARCINOSARCOMA; CELL MIGRATION; CHD4 GENE; CHROMOSOME 6P; CONFERENCE PAPER; CONTROLLED STUDY; COPY NUMBER VARIATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; HUMAN; IMMUNOFLUORESCENCE MICROSCOPY; MAJOR CLINICAL STUDY; MUTATION RATE; OVARY CARCINOMA; PI3 KINASE SUBUNIT ALPHA GENE; PPP2R1A GENE; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SOMATIC MUTATION; TUMOR GENE; TUMOR SUPPRESSOR GENE; UTERUS CARCINOMA; WESTERN BLOTTING; AGED; GENE EXPRESSION REGULATION; GENETICS; MIDDLE AGED; MUTATION; OVARY TUMOR; PATHOLOGY; UTERUS CANCER; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CARCINOSARCOMA; CLASS I PHOSPHATIDYLINOSITOL 3-KINASES; DNA-BINDING PROTEINS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONES; HUMANS; MIDDLE AGED; MUTATION; OVARIAN NEOPLASMS; PTEN PHOSPHOHYDROLASE; TELOMERASE; TUMOR SUPPRESSOR PROTEIN P53; UTERINE NEOPLASMS;

EID: 84992337550     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1614120113     Document Type: Article

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