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Volumn 209, Issue 9, 2016, Pages 417-422

Prevalence of Hispanic BRCA1 and BRCA2 mutations among hereditary breast and ovarian cancer patients from Brazil reveals differences among Latin American populations

Author keywords

BRCA1; BRCA2; Hereditary breast and ovarian cancer

Indexed keywords

ADULT; AGED; ARTICLE; BRAZIL; CANCER PATIENT; CANCER SCREENING; COHORT ANALYSIS; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; FAMILY HISTORY; FEMALE; GENE SEQUENCE; GENOTYPE; GERMLINE MUTATION; HEREDITARY BREAST AND OVARIAN CANCER SYNDROME; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATIONAL ANALYSIS; POPULATION GENETICS; POPULATION RESEARCH; POPULATION STRUCTURE; PREVALENCE; PRIORITY JOURNAL; SOUTH AND CENTRAL AMERICA; TUMOR SUPPRESSOR GENE; BREAST TUMOR; GENETICS; MIDDLE AGED; MUTATION; OVARY TUMOR; YOUNG ADULT;

EID: 84992202237     PISSN: 22107762     EISSN: 22107770     Source Type: Journal    
DOI: 10.1016/j.cancergen.2016.06.008     Document Type: Article
Times cited : (31)

References (45)
  • 1
    • 84918815964 scopus 로고    scopus 로고
    • Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
    • 1 Ferlay, J., Soerjomataram, I., Dikshit, R., et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136 (2015), E359–E386.
    • (2015) Int J Cancer , vol.136 , pp. E359-E386
    • Ferlay, J.1    Soerjomataram, I.2    Dikshit, R.3
  • 3
    • 84863159814 scopus 로고    scopus 로고
    • Breast cancer in Brazil: present status and future goals
    • 3 Lee, B.L., Liedke, P.E., Barrios, C.H., et al. Breast cancer in Brazil: present status and future goals. Lancet Oncol 13 (2012), e95–e102.
    • (2012) Lancet Oncol , vol.13 , pp. e95-e102
    • Lee, B.L.1    Liedke, P.E.2    Barrios, C.H.3
  • 5
    • 51449120932 scopus 로고    scopus 로고
    • Concise handbook of familial cancer susceptibility syndromes—second edition
    • 5 Lindor, N.M., McMaster, M.L., Lindor, C.J., et al. Concise handbook of familial cancer susceptibility syndromes—second edition. J Natl Cancer Inst Monogr, 2008, 1–93.
    • (2008) J Natl Cancer Inst Monogr , pp. 1-93
    • Lindor, N.M.1    McMaster, M.L.2    Lindor, C.J.3
  • 6
    • 0029955159 scopus 로고    scopus 로고
    • The genetic attributable risk of breast and ovarian cancer
    • 6 Claus, E.B., Schildkraut, J.M., Thompson, W.D., et al. The genetic attributable risk of breast and ovarian cancer. Cancer 77 (1996), 2318–2324.
    • (1996) Cancer , vol.77 , pp. 2318-2324
    • Claus, E.B.1    Schildkraut, J.M.2    Thompson, W.D.3
  • 7
    • 84927556016 scopus 로고    scopus 로고
    • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer
    • 7 Rebbeck, T.R., Mitra, N., Wan, F., et al. Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. JAMA 313 (2015), 1347–1361.
    • (2015) JAMA , vol.313 , pp. 1347-1361
    • Rebbeck, T.R.1    Mitra, N.2    Wan, F.3
  • 8
    • 84878450027 scopus 로고    scopus 로고
    • Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer
    • 8 Castro, E., Goh, C., Olmos, D., et al. Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer. J Clin Oncol 31 (2013), 1748–1757.
    • (2013) J Clin Oncol , vol.31 , pp. 1748-1757
    • Castro, E.1    Goh, C.2    Olmos, D.3
  • 9
    • 48249136563 scopus 로고    scopus 로고
    • Rapid progression of prostate cancer in men with a BRCA2 mutation
    • 9 Narod, S.A., Neuhausen, S., Vichodez, G., et al. Rapid progression of prostate cancer in men with a BRCA2 mutation. Br J Cancer 99 (2008), 371–374.
    • (2008) Br J Cancer , vol.99 , pp. 371-374
    • Narod, S.A.1    Neuhausen, S.2    Vichodez, G.3
  • 10
    • 84899478727 scopus 로고    scopus 로고
    • Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from Medellín, Colombia
    • 10 Hernández, J.E., Llacuachaqui, M., Palacio, G.V., et al. Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from Medellín, Colombia. Hered Cancer Clin Pract, 12, 2014, 11.
    • (2014) Hered Cancer Clin Pract , vol.12 , pp. 11
    • Hernández, J.E.1    Llacuachaqui, M.2    Palacio, G.V.3
  • 11
    • 84856018003 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 mutations among ovarian cancer patients from Colombia
    • 11 Rodríguez, A.O., Llacuachaqui, M., Pardo, G.G., et al. BRCA1 and BRCA2 mutations among ovarian cancer patients from Colombia. Gynecol Oncol 124 (2012), 236–243.
    • (2012) Gynecol Oncol , vol.124 , pp. 236-243
    • Rodríguez, A.O.1    Llacuachaqui, M.2    Pardo, G.G.3
  • 12
    • 65649112508 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 mutations in women of different ethnicities undergoing testing for hereditary breast-ovarian cancer
    • 12 Hall, M.J., Reid, J.E., Burbidge, L.A., et al. BRCA1 and BRCA2 mutations in women of different ethnicities undergoing testing for hereditary breast-ovarian cancer. Cancer 115 (2009), 2222–2233.
    • (2009) Cancer , vol.115 , pp. 2222-2233
    • Hall, M.J.1    Reid, J.E.2    Burbidge, L.A.3
  • 13
    • 84872579612 scopus 로고    scopus 로고
    • Prevalence and type of BRCA mutations in Hispanics undergoing genetic cancer risk assessment in the southwestern United States: a report from the Clinical Cancer Genetics Community Research Network
    • 13 Weitzel, J.N., Clague, J., Martir-Negron, A., et al. Prevalence and type of BRCA mutations in Hispanics undergoing genetic cancer risk assessment in the southwestern United States: a report from the Clinical Cancer Genetics Community Research Network. J Clin Oncol 31 (2013), 210–216.
    • (2013) J Clin Oncol , vol.31 , pp. 210-216
    • Weitzel, J.N.1    Clague, J.2    Martir-Negron, A.3
  • 14
    • 80052333832 scopus 로고    scopus 로고
    • Genetics, genomics and cancer risk assessment: state of the art and future directions in the era of personalized medicine
    • 14 Weitzel, J.N., Blazer, K.R., MacDonald, D.J., et al. Genetics, genomics and cancer risk assessment: state of the art and future directions in the era of personalized medicine. CA Cancer J Clin 61 (2011), 327–359.
    • (2011) CA Cancer J Clin , vol.61 , pp. 327-359
    • Weitzel, J.N.1    Blazer, K.R.2    MacDonald, D.J.3
  • 15
    • 80052584408 scopus 로고    scopus 로고
    • Personalized cancer genetics training for personalized medicine: improving community-based healthcare through a genetically literate workforce
    • 15 Blazer, K.R., MacDonald, D.J., Culver, J.O., et al. Personalized cancer genetics training for personalized medicine: improving community-based healthcare through a genetically literate workforce. Genet Med 13 (2011), 832–840.
    • (2011) Genet Med , vol.13 , pp. 832-840
    • Blazer, K.R.1    MacDonald, D.J.2    Culver, J.O.3
  • 16
    • 0029864134 scopus 로고    scopus 로고
    • Statement of the American Society of Clinical Oncology: genetic testing for cancer susceptibility, Adopted on February 20, 1996
    • discussion 1737-1740
    • 16 Statement of the American Society of Clinical Oncology: genetic testing for cancer susceptibility, Adopted on February 20, 1996. J Clin Oncol 14 (1996), 1730–1736 discussion 1737-1740.
    • (1996) J Clin Oncol , vol.14 , pp. 1730-1736
  • 17
    • 84947279527 scopus 로고    scopus 로고
    • American Society of Clinical Oncology policy statement update: genetic and genomic testing for cancer susceptibility
    • 17 Robson, M.E., Bradbury, A.R., Arun, B., et al. American Society of Clinical Oncology policy statement update: genetic and genomic testing for cancer susceptibility. J Clin Oncol 33 (2015), 3660–3667.
    • (2015) J Clin Oncol , vol.33 , pp. 3660-3667
    • Robson, M.E.1    Bradbury, A.R.2    Arun, B.3
  • 18
    • 0037087536 scopus 로고    scopus 로고
    • Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: analysis of 10,000 individuals
    • 18 Frank, T.S., Deffenbaugh, A.M., Reid, J.E., et al. Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: analysis of 10,000 individuals. J Clin Oncol 20 (2002), 1480–1490.
    • (2002) J Clin Oncol , vol.20 , pp. 1480-1490
    • Frank, T.S.1    Deffenbaugh, A.M.2    Reid, J.E.3
  • 19
    • 47149086213 scopus 로고    scopus 로고
    • Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics
    • 19 Antoniou, A.C., Hardy, R., Walker, L., et al. Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics. J Med Genet 45 (2008), 425–431.
    • (2008) J Med Genet , vol.45 , pp. 425-431
    • Antoniou, A.C.1    Hardy, R.2    Walker, L.3
  • 20
    • 84921503732 scopus 로고    scopus 로고
    • Significant clinical impact of recurrent BRCA1 and BRCA2 mutations in Mexico
    • 20 Villarreal-Garza, C., Alvarez-Gómez, R.M., Pérez-Plasencia, C., et al. Significant clinical impact of recurrent BRCA1 and BRCA2 mutations in Mexico. Cancer 121 (2015), 372–378.
    • (2015) Cancer , vol.121 , pp. 372-378
    • Villarreal-Garza, C.1    Alvarez-Gómez, R.M.2    Pérez-Plasencia, C.3
  • 21
    • 26044460481 scopus 로고    scopus 로고
    • Analysis of BRCA1 and BRCA2 mutations in Brazilian breast cancer patients with positive family history
    • 21 Dufloth, R.M., Carvalho, S., Heinrich, J.K., et al. Analysis of BRCA1 and BRCA2 mutations in Brazilian breast cancer patients with positive family history. Sao Paulo Med J 123 (2005), 192–197.
    • (2005) Sao Paulo Med J , vol.123 , pp. 192-197
    • Dufloth, R.M.1    Carvalho, S.2    Heinrich, J.K.3
  • 22
    • 34250664312 scopus 로고    scopus 로고
    • Prevalence of BRCA1 and BRCA2 mutations in breast cancer patients from Brazil
    • 22 Gomes, M.C., Costa, M.M., Borojevic, R., et al. Prevalence of BRCA1 and BRCA2 mutations in breast cancer patients from Brazil. Breast Cancer Res Treat 103 (2007), 349–353.
    • (2007) Breast Cancer Res Treat , vol.103 , pp. 349-353
    • Gomes, M.C.1    Costa, M.M.2    Borojevic, R.3
  • 23
    • 68249160900 scopus 로고    scopus 로고
    • Prevalence of BRCA1 and BRCA2 gene mutations in families with medium and high risk of breast and ovarian cancer in Brazil
    • 23 Esteves, V.F., Thuler, L.C., Amêndola, L.C., et al. Prevalence of BRCA1 and BRCA2 gene mutations in families with medium and high risk of breast and ovarian cancer in Brazil. Braz J Med Biol Res 42 (2009), 453–457.
    • (2009) Braz J Med Biol Res , vol.42 , pp. 453-457
    • Esteves, V.F.1    Thuler, L.C.2    Amêndola, L.C.3
  • 24
    • 84874562871 scopus 로고    scopus 로고
    • Comprehensive analysis of BRCA1, BRCA2 and TP53 germline mutation and tumor characterization: a portrait of early-onset breast cancer in Brazil
    • e57581
    • 24 Carraro, D.M., Koike Folgueira, M.A., Garcia Lisboa, B.C., et al. Comprehensive analysis of BRCA1, BRCA2 and TP53 germline mutation and tumor characterization: a portrait of early-onset breast cancer in Brazil. PLoS ONE, 8, 2013 e57581.
    • (2013) PLoS ONE , vol.8
    • Carraro, D.M.1    Koike Folgueira, M.A.2    Garcia Lisboa, B.C.3
  • 25
    • 84901618645 scopus 로고    scopus 로고
    • Hereditary breast and ovarian cancer: assessment of point mutations and copy number variations in Brazilian patients
    • 25 Silva, F.C., Lisboa, B.C., Figueiredo, M.C., et al. Hereditary breast and ovarian cancer: assessment of point mutations and copy number variations in Brazilian patients. BMC Med Genet, 15, 2014, 55.
    • (2014) BMC Med Genet , vol.15 , pp. 55
    • Silva, F.C.1    Lisboa, B.C.2    Figueiredo, M.C.3
  • 26
    • 84948387036 scopus 로고    scopus 로고
    • Germline mutations in BRCA1, BRCA1, CHEK2 and TP53 in patients at high-risk for HBOC: characterizing a Northeast Brazilian Population
    • 26 Felix, G.E., Abe-Sandes, C., Machado-Lopes, T.M., et al. Germline mutations in BRCA1, BRCA1, CHEK2 and TP53 in patients at high-risk for HBOC: characterizing a Northeast Brazilian Population. Hum Genome Var, 1, 2014, 14012.
    • (2014) Hum Genome Var , vol.1 , pp. 14012
    • Felix, G.E.1    Abe-Sandes, C.2    Machado-Lopes, T.M.3
  • 27
    • 84941631312 scopus 로고    scopus 로고
    • Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from Peru
    • 27 Abugattas, J., Llacuachaqui, M., Allende, Y.S., et al. Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from Peru. Clin Genet 88 (2015), 371–375.
    • (2015) Clin Genet , vol.88 , pp. 371-375
    • Abugattas, J.1    Llacuachaqui, M.2    Allende, Y.S.3
  • 28
    • 84861399847 scopus 로고    scopus 로고
    • Full-exon pyrosequencing screening of BRCA germline mutations in Mexican women with inherited breast and ovarian cancer
    • e37432
    • 28 Vaca-Paniagua, F., Alvarez-Gomez, R.M., Fragoso-Ontiveros, V., et al. Full-exon pyrosequencing screening of BRCA germline mutations in Mexican women with inherited breast and ovarian cancer. PLoS ONE, 7, 2012 e37432.
    • (2012) PLoS ONE , vol.7
    • Vaca-Paniagua, F.1    Alvarez-Gomez, R.M.2    Fragoso-Ontiveros, V.3
  • 29
    • 84873519343 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 analysis of Argentinean breast/ovarian cancer patients selected for age and family history highlights a role for novel mutations of putative south-American origin
    • 29 Solano, A.R., Aceto, G.M., Delettieres, D., et al. BRCA1 and BRCA2 analysis of Argentinean breast/ovarian cancer patients selected for age and family history highlights a role for novel mutations of putative south-American origin. Springerplus, 1, 2012, 20.
    • (2012) Springerplus , vol.1 , pp. 20
    • Solano, A.R.1    Aceto, G.M.2    Delettieres, D.3
  • 30
    • 34249040579 scopus 로고    scopus 로고
    • High proportion of BRCA1/2 founder mutations in Hispanic breast/ovarian cancer families from Colombia
    • 30 Torres, D., Rashid, M.U., Gil, F., et al. High proportion of BRCA1/2 founder mutations in Hispanic breast/ovarian cancer families from Colombia. Breast Cancer Res Treat 103 (2007), 225–232.
    • (2007) Breast Cancer Res Treat , vol.103 , pp. 225-232
    • Torres, D.1    Rashid, M.U.2    Gil, F.3
  • 31
    • 32444447811 scopus 로고    scopus 로고
    • Incidence of BRCA1 and BRCA2 mutations in 54 Chilean families with breast/ovarian cancer, genotype-phenotype correlations
    • 31 Gallardo, M., Silva, A., Rubio, L., et al. Incidence of BRCA1 and BRCA2 mutations in 54 Chilean families with breast/ovarian cancer, genotype-phenotype correlations. Breast Cancer Res Treat 95 (2006), 81–87.
    • (2006) Breast Cancer Res Treat , vol.95 , pp. 81-87
    • Gallardo, M.1    Silva, A.2    Rubio, L.3
  • 32
    • 79958701431 scopus 로고    scopus 로고
    • Spectrum of BRCA1/2 point mutations and genomic rearrangements in high-risk breast/ovarian cancer Chilean families
    • 32 Gonzalez-Hormazabal, P., Gutierrez-Enriquez, S., Gaete, D., et al. Spectrum of BRCA1/2 point mutations and genomic rearrangements in high-risk breast/ovarian cancer Chilean families. Breast Cancer Res Treat 126 (2011), 705–716.
    • (2011) Breast Cancer Res Treat , vol.126 , pp. 705-716
    • Gonzalez-Hormazabal, P.1    Gutierrez-Enriquez, S.2    Gaete, D.3
  • 33
    • 79959268485 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 germline mutations in Uruguayan breast and breast-ovarian cancer families. Identification of novel mutations and unclassified variants
    • 33 Delgado, L., Fernández, G., Grotiuz, G., et al. BRCA1 and BRCA2 germline mutations in Uruguayan breast and breast-ovarian cancer families. Identification of novel mutations and unclassified variants. Breast Cancer Res Treat 128 (2011), 211–218.
    • (2011) Breast Cancer Res Treat , vol.128 , pp. 211-218
    • Delgado, L.1    Fernández, G.2    Grotiuz, G.3
  • 34
    • 0031035359 scopus 로고    scopus 로고
    • The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women
    • 34 Abeliovich, D., Kaduri, L., Lerer, I., et al. The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women. Am J Hum Genet 60 (1997), 505–514.
    • (1997) Am J Hum Genet , vol.60 , pp. 505-514
    • Abeliovich, D.1    Kaduri, L.2    Lerer, I.3
  • 35
    • 0029794992 scopus 로고    scopus 로고
    • Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2
    • 35 Roa, B.B., Boyd, A.A., Volcik, K., et al. Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2. Nat Genet 14 (1996), 185–187.
    • (1996) Nat Genet , vol.14 , pp. 185-187
    • Roa, B.B.1    Boyd, A.A.2    Volcik, K.3
  • 36
    • 79951810477 scopus 로고    scopus 로고
    • On the origin and diffusion of BRCA1 c.5266dupC (5382insC) in European populations
    • 36 Hamel, N., Feng, B.J., Foretova, L., et al. On the origin and diffusion of BRCA1 c.5266dupC (5382insC) in European populations. Eur J Hum Genet 19 (2011), 300–306.
    • (2011) Eur J Hum Genet , vol.19 , pp. 300-306
    • Hamel, N.1    Feng, B.J.2    Foretova, L.3
  • 38
    • 44949118602 scopus 로고    scopus 로고
    • Founder effect of the BRCA1 5382insC mutation in Brazilian patients with hereditary breast ovary cancer syndrome
    • 38 da Costa, E.C., Vargas, F.R., Moreira, A.S., et al. Founder effect of the BRCA1 5382insC mutation in Brazilian patients with hereditary breast ovary cancer syndrome. Cancer Genet Cytogenet 184 (2008), 62–66.
    • (2008) Cancer Genet Cytogenet , vol.184 , pp. 62-66
    • da Costa, E.C.1    Vargas, F.R.2    Moreira, A.S.3
  • 39
    • 34249932412 scopus 로고    scopus 로고
    • Screening for a BRCA2 rearrangement in high-risk breast/ovarian cancer families: evidence for a founder effect and analysis of the associated phenotypes
    • 39 Machado, P.M., Brandão, R.D., Cavaco, B.M., et al. Screening for a BRCA2 rearrangement in high-risk breast/ovarian cancer families: evidence for a founder effect and analysis of the associated phenotypes. J Clin Oncol 25 (2007), 2027–2034.
    • (2007) J Clin Oncol , vol.25 , pp. 2027-2034
    • Machado, P.M.1    Brandão, R.D.2    Cavaco, B.M.3
  • 40
    • 10744232814 scopus 로고    scopus 로고
    • Analysis of BRCA1 and BRCA2 genes in Spanish breast/ovarian cancer patients: a high proportion of mutations unique to Spain and evidence of founder effects
    • 40 Díez, O., Osorio, A., Durán, M., et al. Analysis of BRCA1 and BRCA2 genes in Spanish breast/ovarian cancer patients: a high proportion of mutations unique to Spain and evidence of founder effects. Hum Mutat 22 (2003), 301–312.
    • (2003) Hum Mutat , vol.22 , pp. 301-312
    • Díez, O.1    Osorio, A.2    Durán, M.3
  • 41
    • 17344372404 scopus 로고    scopus 로고
    • Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study
    • 41 Neuhausen, S.L., Godwin, A.K., Gershoni-Baruch, R., et al. Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study. Am J Hum Genet 62 (1998), 1381–1388.
    • (1998) Am J Hum Genet , vol.62 , pp. 1381-1388
    • Neuhausen, S.L.1    Godwin, A.K.2    Gershoni-Baruch, R.3
  • 42
    • 53149125656 scopus 로고    scopus 로고
    • Counseling for male BRCA mutation carriers: a review
    • 42 Mohamad, H.B., Apffelstaedt, J.P., Counseling for male BRCA mutation carriers: a review. Breast 17 (2008), 441–450.
    • (2008) Breast , vol.17 , pp. 441-450
    • Mohamad, H.B.1    Apffelstaedt, J.P.2
  • 44
    • 0031018551 scopus 로고    scopus 로고
    • Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population
    • 44 Friedman, L.S., Gayther, S.A., Kurosaki, T., et al. Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population. Am J Hum Genet 60 (1997), 313–319.
    • (1997) Am J Hum Genet , vol.60 , pp. 313-319
    • Friedman, L.S.1    Gayther, S.A.2    Kurosaki, T.3
  • 45
    • 0030956589 scopus 로고    scopus 로고
    • Study of a single BRCA2 mutation with high carrier frequency in a small population
    • 45 Thorlacius, S., Sigurdsson, S., Bjarnadottir, H., et al. Study of a single BRCA2 mutation with high carrier frequency in a small population. Am J Hum Genet 60 (1997), 1079–1084.
    • (1997) Am J Hum Genet , vol.60 , pp. 1079-1084
    • Thorlacius, S.1    Sigurdsson, S.2    Bjarnadottir, H.3


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