Screening for a BRCA2 rearrangement in high-risk breast/ovarian cancer families: Evidence for a founder effect and analysis of the associated phenotypes

Journal of Clinical Oncology

Volumn 25, Issue 15, 2007, Pages 2027-2034

  Machado, Patrícia M ^a   Brandão, Rita D ^a   Cavaco, Branca M ^a   Eugénio, Joana ^a   Bento, Sandra ^a   Nave, Mónica ^a   Rodrigues, Paula ^a   Fernandes, Aires ^a   Vaz, Fátima ^a  

^a INSTITUTO PORTUGUÊS DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA2 PROTEIN;

ADOLESCENT; ADULT; AGED; ALU SEQUENCE; ARTICLE; BREAST CANCER; CANCER FAMILY; CANCER RISK; CANCER SCREENING; CONTROLLED STUDY; EVIDENCE BASED MEDICINE; FEMALE; FOUNDER EFFECT; GENE AMPLIFICATION; GENE IDENTIFICATION; GENE INSERTION; GENE MUTATION; GENE REARRANGEMENT; GENE SEQUENCE; GENETIC SCREENING; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OVARY CANCER; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; BREAST TUMOR; GENETIC PREDISPOSITION; GENETICS; JEW; MASS SCREENING; MIDDLE AGED; MUTATION; NUCLEOTIDE SEQUENCE; OVARY TUMOR; PEDIGREE;

ADULT; AGED; BRCA2 PROTEIN; BREAST NEOPLASMS; DNA MUTATIONAL ANALYSIS; FEMALE; FOUNDER EFFECT; GENE REARRANGEMENT; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GERM-LINE MUTATION; HUMANS; JEWS; MALE; MASS SCREENING; MIDDLE AGED; OVARIAN NEOPLASMS; PEDIGREE; PHENOTYPE;

EID: 34249932412     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2006.06.9443     Document Type: Article

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