Spectrum of BRCA1/2 point mutations and genomic rearrangements in high-risk breast/ovarian cancer Chilean families

Breast Cancer Research and Treatment

Volumn 126, Issue 3, 2011, Pages 705-716

  Gonzalez Hormazabal, Patricio ^a   Gutierrez Enriquez, Sara ^b,c   Gaete, Daniel ^a   Reyes, Jose M ^d   Peralta, Octavio ^a,d   Waugh, Enrique ^e   Gomez, Fernando ^e   Margarit, Sonia ^f   Bravo, Teresa ^g   Blanco, Rafael ^a   Diez, Orland ^b,h   Jara, Lilian ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b VALL D HEBRON UNIVERSITY HOSPITAL   (Spain)

^c HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^d CLÍNICA LAS CONDES   (Chile)

^e CLÍNICA SANTA MARÍA   (Chile)

^f UNIVERSIDAD DEL DESARROLLO   (Chile)

^g National Cancer Society Corporacion Nacional del Cancer CONAC   (Chile)

^h HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

BRCA1 2; Breast cancer; Chilean population; LGRs; Recurrent mutations

Indexed keywords

ADULT; ARTICLE; BREAST CANCER; CANCER RISK; CHILE; CONTROLLED STUDY; FAMILY; FEMALE; FOUNDER EFFECT; GENE DELETION; GENE DUPLICATION; GENE REARRANGEMENT; GENETIC VARIABILITY; HIGH RISK POPULATION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; ONCOGENE; OVARY CANCER; POINT MUTATION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADULT; BREAST NEOPLASMS; BREAST NEOPLASMS, MALE; CHILE; EXONS; FAMILY HEALTH; FEMALE; FOUNDER EFFECT; GENE REARRANGEMENT; GENES, BRCA1; GENES, BRCA2; HUMANS; INTRONS; MALE; MIDDLE AGED; OVARIAN NEOPLASMS; POINT MUTATION; RISK;

EID: 79958701431     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1170-y     Document Type: Article

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