Uncovering obsessive-compulsive disorder risk genes in a pediatric cohort by high-resolution analysis of copy number variation

Journal of Neurodevelopmental Disorders

Volumn 8, Issue 1, 2016, Pages

  Gazzellone, Matthew J ^a   Zarrei, Mehdi ^a   Burton, Christie L ^b   Walker, Susan ^a   Uddin, Mohammed ^a   Shaheen, S M ^b,c   Coste, Julie ^b   Rajendram, Rageen ^b,d   Schachter, Reva J ^b   Colasanto, Marlena ^b   Hanna, Gregory L ^e   Rosenberg, David R ^f,g   Soreni, Noam ^h   Fitzgerald, Kate D ^e   Marshall, Christian R ^a   Buchanan, Janet A ^a   Merico, Daniele ^a   Arnold, Paul D ^b,c,i   Scherer, Stephen W ^a,d  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g CHILDREN'S HOSPITAL OF MICHIGAN   (United States)

^h MCMASTER UNIVERSITY   (Canada)

ⁱ UNIVERSITY OF CALGARY   (Canada)

Author keywords

Copy number variation; Obsessive compulsive disorder; Pediatrics; Whole exome sequencing

Indexed keywords

ADRA2C PROTEIN; AFF2 PROTEIN; ASTN2 PROTEIN; BTBD9 PROTEIN; CNTN6 PROTEIN; DLGAP1 PROTEIN; DLGAP2 PROTEIN; FAM21C PROTEIN; FRAGILE X MENTAL RETARDATION PROTEIN; MARCH8 PROTEIN; NEUROLIGIN 1; NLGN4X PROTEIN; PROTEIN; PTPRD PROTEIN; SCAFFOLD PROTEIN; SLIT1 PROTEIN; UNCLASSIFIED DRUG; ZFAND4 PROTEIN;

4 AMINOBUTYRIC ACID RELEASE; ARTICLE; ATTENTION DEFICIT DISORDER; AUTISM; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; COPY NUMBER VARIATION; CORPUS STRIATUM; DEPRESSION; DEVELOPMENTAL DISORDER; EXOME; EXON; FEMALE; GENE CLUSTER; GENE DELETION; GENE DUPLICATION; GENE LOCUS; GENERALIZED ANXIETY DISORDER; GENETIC RISK; GENETIC SCREENING; GENETIC VARIATION; GENOTYPE; GILLES DE LA TOURETTE SYNDROME; GLUTAMATERGIC SYNAPSE; HEREDITARY LIABILITY TO PRESSURE PALSY; HUMAN; LEARNING DISORDER; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; NERVE ENDING; NEUROTRANSMITTER RELEASE; OBSESSIVE COMPULSIVE DISORDER; OPPOSITIONAL DEFIANT DISORDER; PANIC; PARALYSIS; PATHOGENESIS; PHENOTYPE; PHOBIA; PRIORITY JOURNAL; SCHIZOPHRENIA; SEASONAL AFFECTIVE DISORDER; SEPARATION ANXIETY; SOCIAL PHOBIA; TIC; TRICHOTILLOMANIA; X CHROMOSOME;

EID: 84992195125     PISSN: 18661947     EISSN: 18661955     Source Type: Journal    
DOI: 10.1186/s11689-016-9170-9     Document Type: Article

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