Diagnostic validity of comorbid bipolar disorder and obsessive-compulsive disorder: A systematic review

Acta Psychiatrica Scandinavica

Volumn 129, Issue 5, 2014, Pages 343-358

  Amerio, A ^a,b   Odone, A ^a,c   Liapis, C C ^b,d   Ghaemi, S N ^e  

^a UNIVERSITY OF PARMA   (Italy)

^b TUFTS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^e TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bipolar disorder; Comorbidity; Obsessive compulsive disorder

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; CLOMIPRAMINE; MOOD STABILIZER; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR;

ALCOHOL ABUSE; BIPOLAR DISORDER; CLINICAL FEATURE; COMORBIDITY; COMPULSION; DEPRESSION; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DISEASE COURSE; FAMILY HISTORY; HEREDITY; HOSPITALIZATION; HUMAN; HYPOMANIA; MENTAL PATIENT; OBSESSION; OBSESSIVE COMPULSIVE DISORDER; PHENOMENOLOGY; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; SCHIZOAFFECTIVE PSYCHOSIS; SUBSTANCE ABUSE; SUICIDAL IDEATION; SUICIDE ATTEMPT; SYSTEMATIC REVIEW; TREATMENT RESPONSE; VALIDITY; YALE BROWN OBSESSIVE COMPULSIVE SCALE; BEHAVIOR; DIAGNOSIS; DISEASE MANAGEMENT; EPIDEMIOLOGY; OBSESSIVE-COMPULSIVE DISORDER; ONSET AGE; OUTCOME ASSESSMENT; PREVALENCE; PSYCHOLOGY; REPRODUCIBILITY;

AGE OF ONSET; BEHAVIORAL SYMPTOMS; BIPOLAR DISORDER; COMORBIDITY; DISEASE MANAGEMENT; EPIDEMIOLOGIC STUDIES; HUMANS; OBSESSIVE-COMPULSIVE DISORDER; OUTCOME ASSESSMENT (HEALTH CARE); PREVALENCE; REPRODUCIBILITY OF RESULTS;

EID: 84898538965     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/acps.12250     Document Type: Review

References (92)

1. Krishnan KR. Psychiatric and medical comorbidities of bipolar disorder. Psychosom Med 2005;67:1-8.
2. Morel BA. Traité des maladies mentales. 2nd edn. Paris: Masson, 1860.
3. Chen YW, Dilsaver SC. Comorbidity for obsessive-compulsive disorder in bipolar and unipolar disorders. Psychiatry Res 1995;59:57-64.
4. Mayer-Gross W, Slater E, Roth M. Clinical psychiatry. 3rd edn. London: Elsevier Health Sciences, 1969.
5. Schruers K, Koning K, Luermans J, Haack MJ, Griez E. Obsessive-compulsive disorder: a critical review of therapeutic perspectives. Acta Psychiatr Scand 2005;111:261-271.
6. Fineberg NA, Reghunandanan S, Brown A, Pampaloni I. Pharmacotherapy of obsessive-compulsive disorder: evidence-based treatment and beyond. Aust N Z J Psychiatry 2013;47:121-141.
7. Keck PE Jr, Lipinski JF Jr, White K. An inverse relationship between mania and obsessive-compulsive disorder: a case report. J Clin Psychopharmacol 1986;6:123-124.
8. Steiner W. Fluoxetine-induced mania in a patient with obsessive-compulsive disorder. Am J Psychiatry 1991;148:1403-1404.
9. Vieta E, Bernardo M. Antidepressant-induced mania in obsessive-compulsive disorder. Am J Psychiatry 1992;149:1282-1283.
10. Vieta E, Bernardo M, Vallejo J. Clomipramine-induced mania in obsessive-compulsive disorder. Hum Psychopharmacol 1991;6:72-73.
11. Tondo L, Vazquez G, Baldessarini RJ. Mania associated with antidepressant treatment: comprehensive meta-analytic review. Acta Psychiatr Scand 2010;121:404-414.
12. Liberati A, Altman DG, Tetzlaff J et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. Br Med J (Clin Res Ed) 2009;339:b2700.
13. Higgins JPT, Green S, eds. Cochrane handbook for systematic reviews of interventions version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from: URL: www.cochrane-handbook.org.
14. Geddes JR, Goodwin GM, Rendell J et al. Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar i disorder (BALANCE): a randomised open-label trial. Lancet 2010;375:385-395.
15. Angst J, Gamma A, Endrass J et al. Obsessive-compulsive severity spectrum in the community: prevalence, comorbidity, and course. Eur Arch Psychiatry Clin Neurosci 2004;254:156-164.
16. Angst J, Gamma A, Endrass J et al. Obsessive-compulsive syndromes and disorders: significance of comorbidity with bipolar and anxiety syndromes. Eur Arch Psychiatry Clin Neurosci 2005;255:65-71.
17. Hantouche EG, Angst J, Demonfaucon C, Perugi G, Lancrenon S, Akiskal HS. Cyclothymic OCD: a distinct form? J Affect Disord 2003;75:1-10.
18. Bachen EA, Chesney MA, Criswell LA. Prevalence of mood and anxiety disorders in women with systemic lupus erythematosus. Arthritis Rheum 2009;61:822-829.
19. Mukaddes NM, Fateh R. High rates of psychiatric co-morbidity in individuals with Asperger's disorder. World J Biol Psychiatry 2010;11:486-492.
20. Dell'Osso B, Buoli M, Bortolussi S, Camuri G, Vecchi V, Altamura AC. Patterns of Axis I comorbidity in relation to age in patients with Bipolar Disorder: a cross-sectional analysis. J Affect Disord 2011;130:318-322.
21. Robins E, Guze SB. Establishment of diagnostic validity in psychiatric illness: its application to schizophrenia. Am J Psychiatry 1970;126:983-987.
22. Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health 1998;52:377-384.
23. Faravelli C, Abrardi L, Bartolozzi D et al. The Sesto Fiorentino study: background, methods and preliminary results. Lifetime prevalence of psychiatric disorders in an Italian community sample using clinical interviewers. Psychother Psychosom 2004;73:216-225.
24. Merikangas KR, Akiskal HS, Angst J et al. Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. Arch Gen Psychiatry 2007;64:543-552.
25. Craig T, Hwang MY, Bromet EJ. Obsessive-compulsive and panic symptoms in patients with first-admission psychosis. Am J Psychiatry 2002;159:592-598.
26. Henry C, Van Den Bulke D, Bellivier F, Etain B, Rouillon F, Leboyer M. Anxiety disorders in 318 bipolar patients: prevalence and impact on illness severity and response to mood stabilizer. J Clin Psychiatry 2003;64:331-335.
27. Saunders EF, Fitzgerald KD, Zhang P, McInnis MG. Clinical features of bipolar disorder comorbid with anxiety disorders differ between men and women. Depress Anxiety 2012;29:739-746.
28. Boylan KR, Bieling PJ, Marriott M, Begin H, Young LT, MacQueen GM. Impact of comorbid anxiety disorders on outcome in a cohort of patients with bipolar disorder. J Clin Psychiatry 2004;65:1106-1113.
29. Strakowski SM, Sax KW, McElroy SL, Keck PE Jr, Hawkins JM, West SA. Course of psychiatric and substance abuse syndromes co-occurring with bipolar disorder after a first psychiatric hospitalization. J Clin Psychiatry 1998;59:465-471.
30. Koyuncu A, Tukel R, Ozyildirim I, Meteris H, Yazici O. Impact of obsessive-compulsive disorder comorbidity on the sociodemographic and clinical features of patients with bipolar disorder. Compr Psychiatry 2010;51:293-297.
31. Magalhaes PV, Kapczinski NS, Kapczinski F. Correlates and impact of obsessive-compulsive comorbidity in bipolar disorder. Compr Psychiatry 2010;51:353-356.
32. Simon NM, Smoller JW, Fava M et al. Comparing anxiety disorders and anxiety-related traits in bipolar disorder and unipolar depression. J Psychiatr Res 2003;37:187-192.
33. Edmonds LK, Mosley BJ, Admiraal AJ et al. Familial bipolar disorder: preliminary results from the Otago Familial Bipolar Genetic Study. Aust N Z J Psychiatry 1998;32:823-829.
34. Cosoff SJ, Hafner RJ. The prevalence of comorbid anxiety in schizophrenia, schizoaffective disorder and bipolar disorder. Aust N Z J Psychiatry 1998;32:67-72.
35. Strakowski SM, Tohen M, Stoll AL, Faedda GL, Goodwin DC. Comorbidity in mania at first hospitalization. Am J Psychiatry 1992;149:554-556.
36. Krüger S, Cooke RG, Hasey GM, Jorna T. Comorbidity of obsessive compulsive disorder in bipolar disorder. J Affect Disord 1995;34:117-120.
37. Kruger S, Braunig P, Cooke RG. Comorbidity of obsessive-compulsive disorder in recovered inpatients with bipolar disorder. Bipolar Disord 2000;2:71-74.
38. McElroy SL, Altshuler LL, Suppes T et al. Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder. Am J Psychiatry 2001;158:420-426.
39. Simon NM, Otto MW, Wisniewski SR et al. Anxiety disorder comorbidity in bipolar disorder patients: data from the first 500 participants in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Am J Psychiatry 2004;161:2222-2229.
40. Pini S, Cassano GB, Simonini E, Savino M, Russo A, Montgomery SA. Prevalence of anxiety disorders comorbidity in bipolar depression, unipolar depression and dysthymia. J Affect Disord 1997;42:145-153.
41. Zutshi A, Reddy YC, Thennarasu K, Chandrashekhar CR. Comorbidity of anxiety disorders in patients with remitted bipolar disorder. Eur Arch Psychiatry Clin Neurosci 2006;256:428-436.
42. Tamam L, Ozpoyraz N. Comorbidity of anxiety disorder among patients with bipolar I disorder in remission. Psychopathology 2002;35:203-209.
43. Joshi G, Wozniak J, Petty C et al. Clinical characteristics of comorbid obsessive-compulsive disorder and bipolar disorder in children and adolescents. Bipolar Disord 2010;12:185-195.
44. Tillman R, Geller B, Bolhofner K, Craney JL, Williams M, Zimerman B. Ages of onset and rates of syndromal and subsyndromal comorbid DSM-IV diagnoses in a prepubertal and early adolescent bipolar disorder phenotype. J Am Acad Child Adolesc Psychiatry 2003;42:1486-1493.
45. Dilsaver SC, Akiskal HS, Akiskal KK, Benazzi F. Dose-response relationship between number of comorbid anxiety disorders in adolescent bipolar/unipolar disorders, and psychosis, suicidality, substance abuse and familiality. J Affect Disord 2006;96:249-258.
46. Fireman B, Koran LM, Leventhal JL, Jacobson A. The prevalence of clinically recognized obsessive-compulsive disorder in a large health maintenance organization. Am J Psychiatry 2001;158:1904-1910.
47. Adam Y, Meinlschmidt G, Gloster AT, Lieb R. Obsessive-compulsive disorder in the community: 12-month prevalence, comorbidity and impairment. Soc Psychiatry Psychiatr Epidemiol 2012;47:339-349.
48. Angst J, Gamma A, Benazzi F, Ajdacic V, Eich D, Rossler W. Toward a re-definition of subthreshold bipolarity: epidemiology and proposed criteria for bipolar-II, minor bipolar disorders and hypomania. J Affect Disord 2003;73:133-146.
49. Maina G, Albert U, Pessina E, Bogetto F. Bipolar obsessive-compulsive disorder and personality disorders. Bipolar Disord 2007;9:722-729.
50. Marazziti D, Dell'Osso L, Di Nasso E et al. Insight in obsessive-compulsive disorder: a study of an Italian sample. Eur Psychiatry, 2002;17:407-410.
51. Timpano KR, Rubenstein LM, Murphy DL. Phenomenological features and clinical impact of affective disorders in OCD: a focus on the bipolar disorder and OCD connection. Depress Anxiety 2012;29:226-233.
52. Perugi G, Akiskal HS, Gemignani A et al. Episodic course in obsessive-compulsive disorder. Eur Arch Psychiatry Clin Neurosci 1998;248:240-244.
53. Perugi G, Akiskal HS, Pfanner C et al. The clinical impact of bipolar and unipolar affective comorbidity on obsessive-compulsive disorder. J Affect Disord 1997;46:15-23.
54. Perugi G, Akiskal HS, Ramacciotti S et al. Depressive comorbidity of panic, social phobic, and obsessive-compulsive disorders re-examined: is there a bipolar II connection? J Psychiatr Res 1999;33:53-61.
55. Perugi G, Toni C, Frare F, Travierso MC, Hantouche E, Akiskal HS. Obsessive-compulsive-bipolar comorbidity: a systematic exploration of clinical features and treatment outcome. J Clin Psychiatry 2002;63:1129-1134.
56. Diniz JB, Rosario-Campos MC, Shavitt RG et al. Impact of age at onset and duration of illness on the expression of comorbidities in obsessive-compulsive disorder. J Clin Psychiatry 2004;65:22-27.
57. Tukel R, Oflaz SB, Ozyildirim I et al. Comparison of clinical characteristics in episodic and chronic obsessive-compulsive disorder. Depress Anxiety 2007;24:251-255.
58. Lensi P, Cassano GB, Correddu G, Ravagli S, Kunovac JJ. Obsessive-compulsive disorder. Familial-developmental history, symptomatology, comorbidity and course with special reference to gender-related differences. Br J Psychiatry 1996;169:101-107.
59. Masi G, Millepiedi S, Mucci M, Bertini N, Milantoni L, Arcangeli F. A naturalistic study of referred children and adolescents with obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry 2005;44:673-681.
60. Masi G, Millepiedi S, Perugi G et al. Pharmacotherapy in paediatric obsessive-compulsive disorder: a naturalistic, retrospective study. CNS Drugs 2009;23:241-252.
61. Masi G, Millepiedi S, Perugi G et al. A naturalistic exploratory study of the impact of demographic, phenotypic and comorbid features in pediatric obsessive-compulsive disorder. Psychopathology 2010;43:69-78.
62. Masi G, Perugi G, Millepiedi S et al. Bipolar co-morbidity in pediatric obsessive-compulsive disorder: clinical and treatment implications. J Child Adolesc Psychopharmacol 2007;17:475-486.
63. Reddy YC, Reddy PS, Srinath S, Khanna S, Sheshadri SP, Girimaji SC. Comorbidity in juvenile obsessive-compulsive disorder: a report from India. Can J Psychiatry 2000;45:274-278.
64. Zutshi A, Kamath P, Reddy YC. Bipolar and nonbipolar obsessive-compulsive disorder: a clinical exploration. Compr Psychiatry 2007;48:245-251.
65. Mahasuar R, Janardhan Reddy YC, Math SB. Obsessive-compulsive disorder with and without bipolar disorder. Psychiatry Clin Neurosci 2011;65:423-433.
66. McElroy SL, Strakowski SM, Keck PE Jr, Tugrul KL, West SA, Lonczak HS. Differences and similarities in mixed and pure mania. Compr Psychiatry 1995;36:187-194.
67. Dell'Osso L, Pini S, Tundo A, Sarno N, Musetti L, Cassano GB. Clinical characteristics of mania, mixed mania, and bipolar depression with psychotic features. Compr Psychiatry, 2000;41:242-247.
68. Shabani A, Alizadeh A. The specific pattern of obsessive-compulsive symptoms in patients with bipolar disorder. J Res Med Sci 2008;13:48-54.
69. Hasler G, Lasalle-Ricci VH, Ronquillo JG et al. Obsessive-compulsive disorder symptom dimensions show specific relationships to psychiatric comorbidity. Psychiatry Res 2005;135:121-132.
70. Issler CK, Amaral JA, Tamada RS et al. Clinical expression of obsessive-compulsive disorder in women with bipolar disorder. Rev Bras Psiquiatr 2005;27:139-142.
71. Tukel R, Meteris H, Koyuncu A, Tecer A, Yazici O. The clinical impact of mood disorder comorbidity on obsessive-compulsive disorder. Eur Arch Psychiatry Clin Neurosci 2006;256:240-245.
72. Lasalle-Ricci VH, Arnkoff DB, Glass CR, Crawley SA, Ronquillo JG, Murphy DL. The hoarding dimension of OCD: psychological comorbidity and the five-factor personality model. Behav Res Ther 2006;44:1503-1512.
73. Masi G, Perugi G, Toni C et al. Obsessive-compulsive bipolar comorbidity: focus on children and adolescents. J Affect Disord 2004;78:175-183.
74. Issler CK, Monkul ES, De Mello Siqueira Amaral JA et al. Bipolar disorder and comorbid obsessive-compulsive disorder is associated with higher rates of anxiety and impulse control disorders. Acta Neuropsychiatr 2010;22:81-86.
75. Goes FS, McCusker MG, Bienvenu OJ et al. Co-morbid anxiety disorders in bipolar disorder and major depression: familial aggregation and clinical characteristics of co-morbid panic disorder, social phobia, specific phobia and obsessive-compulsive disorder. Psychol Med 2012;42:1449-1459.
76. Centorrino F, Hennen J, Mallya G, Egli S, Clark T, Baldessarini RJ. Clinical outcome in patients with bipolar I disorder, obsessive compulsive disorder or both. Hum Psychopharmacol 2006;21:189-193.
77. Cannon DM, Ichise M, Fromm SJ et al. Serotonin Transporter Binding in Bipolar Disorder Assessed using [11C] DASB and Positron Emission Tomography. Biol Psychiatry 2006;60:207-217.
78. Joshi G, Mick E, Wozniak J et al. Impact of obsessive-compulsive disorder on the antimanic response to olanzapine therapy in youth with bipolar disorder. Bipolar Disord 2010;12:196-204.
79. Kraepelin E. Manic-depressive insanity and paranoia. Edinburgh: E & S Livingstone, 1921.
80. Surtees PG, Kendell RE. The hierarchy model of psychiatric symptomatology: an investigation based on present state examination ratings. Br J Psychiatry 1979;135:438-443.
81. Bisol LW, Lara DR. Improvement of obsessive-compulsive disorder with divalproex and lamotrigine in two patients with bipolar II disorder. Pharmacopsychiatry 2009;42:37-39.
82. Raja M, Azzoni A. Clinical management of obsessive-compulsive-bipolar comorbidity: a case series. Bipolar Disord 2004;6:264-270.
83. Uguz F. Successful treatment of comorbid obsessive-compulsive disorder with aripiprazole in three patients with bipolar disorder. Gen Hosp Psychiatry 2010;32:556-558.
84. Perlis RH, Ostacher MJ, Patel JK et al. Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Am J Psychiatry 2006;163:217-224.
85. Hill AB. The environment and disease: association or causation? Proc R Soc Med 1965;58:295-300.
86. Feinstein AR. The pre-therapeutic classification of co-morbidity in chronic disease. J Chronic Dis 1970;23:455-468.
87. Maj M. 'Psychiatric comorbidity': an artefact of current diagnostic systems? Br J Psychiatry 2005;186:182-184.
88. Bogetto F, Venturello S, Albert U, Maina G, Ravizza L. Gender-related clinical differences in obsessive-compulsive disorder. Eur Psychiatry 1999;14:434-441.
89. Cassano GB, Pini S, Saettoni M, Dell'Osso L. Multiple anxiety disorder comorbidity in patients with mood spectrum disorders with psychotic features. Am J Psychiatry 1999;156:474-476.
90. Dilsaver SC, Benazzi F, Akiskal KK, Akiskal HS. Differential patterns of lifetime multiple anxiety disorder comorbidity between Latino adults with bipolar I and major depressive disorders. Bull Menninger Clin 2008;72:130-148.
91. Ortiz A, Bradler K, Slaney C et al. An admixture analysis of the age at index episodes in bipolar disorder. Psychiatry Res 2011;188:34-39.
92. Pini S, Dell'Osso L, Mastrocinque C et al. Axis I comorbidity in bipolar disorder with psychotic features. Br J Psychiatry 1999;175:467-471.