메뉴 건너뛰기




Volumn 28, Issue 3, 2016, Pages 241-249

Complement inhibition in C3 glomerulopathy

Author keywords

C3 glomerulonephritis; C3 glomerulopathy; Complement; Dense deposit disease; Eculizumab; Membranoproliferative glomerulonephritis

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENT; COMPLEMENT COMPONENT C3; ECULIZUMAB; COMPLEMENT INHIBITOR;

EID: 84991834342     PISSN: 10445323     EISSN: 10963618     Source Type: Journal    
DOI: 10.1016/j.smim.2016.06.002     Document Type: Review
Times cited : (39)

References (72)
  • 3
    • 77955883153 scopus 로고    scopus 로고
    • Complement: a key system for immune surveillance and homeostasis
    • [3] Ricklin, D., Hajishengallis, G., Yang, K., Lambris, J.D., Complement: a key system for immune surveillance and homeostasis. Nat. Immunol. 11:9 (2010), 785–797.
    • (2010) Nat. Immunol. , vol.11 , Issue.9 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 5
    • 33745712069 scopus 로고    scopus 로고
    • The role of complement in danger sensing and transmission
    • [5] Kohl, J., The role of complement in danger sensing and transmission. Immunol. Res. 34:2 (2006), 157–176.
    • (2006) Immunol. Res. , vol.34 , Issue.2 , pp. 157-176
    • Kohl, J.1
  • 6
    • 84876819390 scopus 로고    scopus 로고
    • International union of basic and clinical pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors
    • [6] Klos, A., Wende, E., Wareham, K.J., Monk, P.N., International union of basic and clinical pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors. Pharmacol. Rev. 65:1 (2013), 500–543.
    • (2013) Pharmacol. Rev. , vol.65 , Issue.1 , pp. 500-543
    • Klos, A.1    Wende, E.2    Wareham, K.J.3    Monk, P.N.4
  • 10
    • 34548392741 scopus 로고    scopus 로고
    • A descriptive study of individuals with membranoproliferative glomerulonephritis
    • (quiz 303)
    • [10] Lu, D.F., McCarthy, A.M., Lanning, L.D., Delaney, C., Porter, C., A descriptive study of individuals with membranoproliferative glomerulonephritis. Nephrol. Nurs. J. 34:3 (2007), 295–302 (quiz 303).
    • (2007) Nephrol. Nurs. J. , vol.34 , Issue.3 , pp. 295-302
    • Lu, D.F.1    McCarthy, A.M.2    Lanning, L.D.3    Delaney, C.4    Porter, C.5
  • 15
    • 0026549476 scopus 로고
    • Activation of the alternative pathway of complement by monoclonal lambda light chains in membranoproliferative glomerulonephritis
    • [15] Meri, S., Koistinen, V., Miettinen, A., Tornroth, T., Seppala, I.J., Activation of the alternative pathway of complement by monoclonal lambda light chains in membranoproliferative glomerulonephritis. J. Exp. Med. 175:4 (1992), 939–950.
    • (1992) J. Exp. Med. , vol.175 , Issue.4 , pp. 939-950
    • Meri, S.1    Koistinen, V.2    Miettinen, A.3    Tornroth, T.4    Seppala, I.J.5
  • 16
    • 0032875669 scopus 로고    scopus 로고
    • Nephritogenic lambda light chain dimer: a unique human miniautoantibody against complement factor H
    • [16] Jokiranta, T.S., Solomon, A., Pangburn, M.K., Zipfel, P.F., Meri, S., Nephritogenic lambda light chain dimer: a unique human miniautoantibody against complement factor H. J. Immunol. 163:8 (1999), 4590–4596.
    • (1999) J. Immunol. , vol.163 , Issue.8 , pp. 4590-4596
    • Jokiranta, T.S.1    Solomon, A.2    Pangburn, M.K.3    Zipfel, P.F.4    Meri, S.5
  • 18
    • 84863442729 scopus 로고    scopus 로고
    • Clinical features and outcomes of 98 children and adults with dense deposit disease
    • [18] Lu, D.F., Moon, M., Lanning, L.D., McCarthy, A.M., Smith, R.J., Clinical features and outcomes of 98 children and adults with dense deposit disease. Pediatr. Nephrol. 27:5 (2012), 773–781.
    • (2012) Pediatr. Nephrol. , vol.27 , Issue.5 , pp. 773-781
    • Lu, D.F.1    Moon, M.2    Lanning, L.D.3    McCarthy, A.M.4    Smith, R.J.5
  • 20
    • 9244237001 scopus 로고    scopus 로고
    • Outcome of idiopathic membranoproliferative glomerulonephritis in children. Arbeitsgemeinschaft Padiatrische Nephrologie
    • [20] Schwertz, R., de Jong, R., Gretz, N., Kirschfink, M., Anders, D., Scharer, K., Outcome of idiopathic membranoproliferative glomerulonephritis in children. Arbeitsgemeinschaft Padiatrische Nephrologie. Acta Paediatr. 85:3 (1996), 308–312.
    • (1996) Acta Paediatr. , vol.85 , Issue.3 , pp. 308-312
    • Schwertz, R.1    de Jong, R.2    Gretz, N.3    Kirschfink, M.4    Anders, D.5    Scharer, K.6
  • 22
    • 0031885010 scopus 로고    scopus 로고
    • In situ complement activation in porcine membranoproliferative glomerulonephritis type II
    • [22] Jansen, J.H., Hogasen, K., Harboe, M., Hovig, T., In situ complement activation in porcine membranoproliferative glomerulonephritis type II. Kidney Int. 53:2 (1998), 331–349.
    • (1998) Kidney Int. , vol.53 , Issue.2 , pp. 331-349
    • Jansen, J.H.1    Hogasen, K.2    Harboe, M.3    Hovig, T.4
  • 23
    • 0036900126 scopus 로고    scopus 로고
    • The molecular basis for hereditary porcine membranoproliferative glomerulonephritis type II: point mutations in the factor H coding sequence block protein secretion
    • [23] Hegasy, G.A., Manuelian, T., Hogasen, K., Jansen, J.H., Zipfel, P.F., The molecular basis for hereditary porcine membranoproliferative glomerulonephritis type II: point mutations in the factor H coding sequence block protein secretion. Am. J. Pathol. 161:6 (2002), 2027–2034.
    • (2002) Am. J. Pathol. , vol.161 , Issue.6 , pp. 2027-2034
    • Hegasy, G.A.1    Manuelian, T.2    Hogasen, K.3    Jansen, J.H.4    Zipfel, P.F.5
  • 24
    • 0027203697 scopus 로고
    • Porcine membranoproliferative glomerulonephritis with intramembranous dense deposits (porcine dense deposit disease)
    • [24] Jansen, J.H., Porcine membranoproliferative glomerulonephritis with intramembranous dense deposits (porcine dense deposit disease). APMIS 101:4 (1993), 281–289.
    • (1993) APMIS , vol.101 , Issue.4 , pp. 281-289
    • Jansen, J.H.1
  • 25
    • 0036699540 scopus 로고    scopus 로고
    • Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H
    • [25] Pickering, M.C., Cook, H.T., Warren, J., Bygrave, A.E., Moss, J., Walport, M.J., Botto, M., Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Nat. Genet. 31:4 (2002), 424–428.
    • (2002) Nat. Genet. , vol.31 , Issue.4 , pp. 424-428
    • Pickering, M.C.1    Cook, H.T.2    Warren, J.3    Bygrave, A.E.4    Moss, J.5    Walport, M.J.6    Botto, M.7
  • 26
    • 77954761090 scopus 로고    scopus 로고
    • Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice
    • [26] Fakhouri, F., de Jorge, E.G., Brune, F., Azam, P., Cook, H.T., Pickering, M.C., Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice. Kidney Int. 78:3 (2010), 279–286.
    • (2010) Kidney Int. , vol.78 , Issue.3 , pp. 279-286
    • Fakhouri, F.1    de Jorge, E.G.2    Brune, F.3    Azam, P.4    Cook, H.T.5    Pickering, M.C.6
  • 30
    • 0037396993 scopus 로고    scopus 로고
    • Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome
    • [30] Manuelian, T., Hellwage, J., Meri, S., Caprioli, J., Noris, M., Heinen, S., Jozsi, M., Neumann, H.P., Remuzzi, G., Zipfel, P.F., Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome. J. Clin. Invest. 111:8 (2003), 1181–1190.
    • (2003) J. Clin. Invest. , vol.111 , Issue.8 , pp. 1181-1190
    • Manuelian, T.1    Hellwage, J.2    Meri, S.3    Caprioli, J.4    Noris, M.5    Heinen, S.6    Jozsi, M.7    Neumann, H.P.8    Remuzzi, G.9    Zipfel, P.F.10
  • 31
    • 0030823285 scopus 로고    scopus 로고
    • Human factor H deficiency. Mutations in framework cysteine residues and block in H protein secretion and intracellular catabolism
    • [31] Ault, B.H., Schmidt, B.Z., Fowler, N.L., Kashtan, C.E., Ahmed, A.E., Vogt, B.A., Colten, H.R., Human factor H deficiency. Mutations in framework cysteine residues and block in H protein secretion and intracellular catabolism. J. Biol. Chem. 272:40 (1997), 25168–25175.
    • (1997) J. Biol. Chem. , vol.272 , Issue.40 , pp. 25168-25175
    • Ault, B.H.1    Schmidt, B.Z.2    Fowler, N.L.3    Kashtan, C.E.4    Ahmed, A.E.5    Vogt, B.A.6    Colten, H.R.7
  • 33
    • 67650508077 scopus 로고    scopus 로고
    • The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome
    • [33] Dragon-Durey, M.A., Blanc, C., Marliot, F., Loirat, C., Blouin, J., Sautes-Fridman, C., Fridman, W.H., Fremeaux-Bacchi, V., The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome. J. Med. Genet. 46:7 (2009), 447–450.
    • (2009) J. Med. Genet. , vol.46 , Issue.7 , pp. 447-450
    • Dragon-Durey, M.A.1    Blanc, C.2    Marliot, F.3    Loirat, C.4    Blouin, J.5    Sautes-Fridman, C.6    Fridman, W.H.7    Fremeaux-Bacchi, V.8
  • 36
    • 79952280131 scopus 로고    scopus 로고
    • Complement factor H deficiency and endocapillary glomerulonephritis due to paternal isodisomy and a novel factor H mutation
    • [36] Schejbel, L., Schmidt, I.M., Kirchhoff, M., Andersen, C.B., Marquart, H.V., Zipfel, P., Garred, P., Complement factor H deficiency and endocapillary glomerulonephritis due to paternal isodisomy and a novel factor H mutation. Genes Immun. 12:2 (2011), 90–99.
    • (2011) Genes Immun. , vol.12 , Issue.2 , pp. 90-99
    • Schejbel, L.1    Schmidt, I.M.2    Kirchhoff, M.3    Andersen, C.B.4    Marquart, H.V.5    Zipfel, P.6    Garred, P.7
  • 37
    • 0033597315 scopus 로고    scopus 로고
    • Disruption of disulfide bonds is responsible for impaired secretion in human complement factor H deficiency
    • [37] Schmidt, B.Z., Fowler, N.L., Hidvegi, T., Perlmutter, D.H., Colten, H.R., Disruption of disulfide bonds is responsible for impaired secretion in human complement factor H deficiency. J. Biol. Chem. 274:17 (1999), 11782–11788.
    • (1999) J. Biol. Chem. , vol.274 , Issue.17 , pp. 11782-11788
    • Schmidt, B.Z.1    Fowler, N.L.2    Hidvegi, T.3    Perlmutter, D.H.4    Colten, H.R.5
  • 44
    • 84904461594 scopus 로고    scopus 로고
    • A novel CFHR5 mutation associated with C3 glomerulonephritis in a Turkish girl
    • [44] Besbas, N., Gulhan, B., Gucer, S., Korkmaz, E., Ozaltin, F., A novel CFHR5 mutation associated with C3 glomerulonephritis in a Turkish girl. J. Nephrol. 27:4 (2014), 457–460.
    • (2014) J. Nephrol. , vol.27 , Issue.4 , pp. 457-460
    • Besbas, N.1    Gulhan, B.2    Gucer, S.3    Korkmaz, E.4    Ozaltin, F.5
  • 45
    • 79960375937 scopus 로고    scopus 로고
    • The identification of CFHR5 nephropathy
    • [45] Gale, D.P., The identification of CFHR5 nephropathy. J. R. Soc. Med. 104:5 (2011), 186–190.
    • (2011) J. R. Soc. Med. , vol.104 , Issue.5 , pp. 186-190
    • Gale, D.P.1
  • 47
    • 84897954452 scopus 로고    scopus 로고
    • A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry
    • [47] Medjeral-Thomas, N., Malik, T.H., Patel, M.P., Toth, T., Cook, H.T., Tomson, C., Pickering, M.C., A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry. Kidney Int. 85:4 (2014), 933–937.
    • (2014) Kidney Int. , vol.85 , Issue.4 , pp. 933-937
    • Medjeral-Thomas, N.1    Malik, T.H.2    Patel, M.P.3    Toth, T.4    Cook, H.T.5    Tomson, C.6    Pickering, M.C.7
  • 53
    • 77950628002 scopus 로고    scopus 로고
    • Anti-factor B autoantibody in dense deposit disease
    • [53] Strobel, S., Zimmering, M., Papp, K., Prechl, J., Jozsi, M., Anti-factor B autoantibody in dense deposit disease. Mol. Immunol. 47:7-8 (2010), 1476–1483.
    • (2010) Mol. Immunol. , vol.47 , Issue.7-8 , pp. 1476-1483
    • Strobel, S.1    Zimmering, M.2    Papp, K.3    Prechl, J.4    Jozsi, M.5
  • 54
    • 0028290534 scopus 로고
    • Occurrence of C3 nephritic factor and C4 nephritic factor in membranoproliferative glomerulonephritis (MPGN)
    • [54] Ohi, H., Yasugi, T., Occurrence of C3 nephritic factor and C4 nephritic factor in membranoproliferative glomerulonephritis (MPGN). Clin. Exp. Immunol. 95:2 (1994), 316–321.
    • (1994) Clin. Exp. Immunol. , vol.95 , Issue.2 , pp. 316-321
    • Ohi, H.1    Yasugi, T.2
  • 55
    • 0024498633 scopus 로고
    • C3 nephritic factor and C4 nephritic factor in the serum of two patients with hypocomplementaemic membranoproliferative glomerulonephritis
    • [55] Tanuma, Y., Ohi, H., Watanabe, S., Seki, M., Hatano, M., C3 nephritic factor and C4 nephritic factor in the serum of two patients with hypocomplementaemic membranoproliferative glomerulonephritis. Clin. Exp. Immunol. 76:1 (1989), 82–85.
    • (1989) Clin. Exp. Immunol. , vol.76 , Issue.1 , pp. 82-85
    • Tanuma, Y.1    Ohi, H.2    Watanabe, S.3    Seki, M.4    Hatano, M.5
  • 57
    • 84858671433 scopus 로고    scopus 로고
    • Eculizumab in a patient with dense-deposit disease
    • [57] Daina, E., Noris, M., Remuzzi, G., Eculizumab in a patient with dense-deposit disease. N. Engl. J. Med. 366:12 (2012), 1161–1163.
    • (2012) N. Engl. J. Med. , vol.366 , Issue.12 , pp. 1161-1163
    • Daina, E.1    Noris, M.2    Remuzzi, G.3
  • 58
    • 84922481583 scopus 로고    scopus 로고
    • Successful long-term outcome of kidney transplantation in a patient with X-linked thrombocytopenia: 9-year follow-up
    • [58] Garnier, A.S., Augusto, J.F., Pellier, I., Subra, J.F., Sayegh, J., Successful long-term outcome of kidney transplantation in a patient with X-linked thrombocytopenia: 9-year follow-up. Transplantation 98:6 (2014), e57–8.
    • (2014) Transplantation , vol.98 , Issue.6 , pp. e57-8
    • Garnier, A.S.1    Augusto, J.F.2    Pellier, I.3    Subra, J.F.4    Sayegh, J.5
  • 61
    • 84942087191 scopus 로고    scopus 로고
    • Eculizumab-induced reversal of dialysis-dependent kidney failure from C3 glomerulonephritis
    • [61] Inman, M., Prater, G., Fatima, H., Wallace, E., Eculizumab-induced reversal of dialysis-dependent kidney failure from C3 glomerulonephritis. Clin. Kidney J. 8:4 (2015), 445–448.
    • (2015) Clin. Kidney J. , vol.8 , Issue.4 , pp. 445-448
    • Inman, M.1    Prater, G.2    Fatima, H.3    Wallace, E.4
  • 62
    • 84885961150 scopus 로고    scopus 로고
    • Evolution of immunoglobulin deposition in C3-dominant membranoproliferative glomerulopathy
    • [62] Kerns, E., Rozansky, D., Troxell, M.L., Evolution of immunoglobulin deposition in C3-dominant membranoproliferative glomerulopathy. Pediatr. Nephrol. 28:11 (2013), 2227–2231.
    • (2013) Pediatr. Nephrol. , vol.28 , Issue.11 , pp. 2227-2231
    • Kerns, E.1    Rozansky, D.2    Troxell, M.L.3
  • 64
    • 84859421387 scopus 로고    scopus 로고
    • Recurrent dense deposit disease after renal transplantation: an emerging role for complementary therapies
    • [64] McCaughan, J.A., O'Rourke, D.M., Courtney, A.E., Recurrent dense deposit disease after renal transplantation: an emerging role for complementary therapies. Am. J. Transplant. 12:4 (2012), 1046–1051.
    • (2012) Am. J. Transplant. , vol.12 , Issue.4 , pp. 1046-1051
    • McCaughan, J.A.1    O'Rourke, D.M.2    Courtney, A.E.3
  • 70
    • 84858661698 scopus 로고    scopus 로고
    • Eculizumab for the treatment of dense-deposit disease
    • [70] Vivarelli, M., Pasini, A., Emma, F., Eculizumab for the treatment of dense-deposit disease. N. Engl. J. Med. 366:12 (2012), 1163–1165.
    • (2012) N. Engl. J. Med. , vol.366 , Issue.12 , pp. 1163-1165
    • Vivarelli, M.1    Pasini, A.2    Emma, F.3
  • 72
    • 84983122043 scopus 로고    scopus 로고
    • Compstatin analog Cp40 inhibits complement dysregulation in vitro in C3 glomerulopathy
    • [72] Zhang, Y., Shao, D., Ricklin, D., Hilkin, B.M., Nester, C.M., Lambris, J.D., Smith, R.J., Compstatin analog Cp40 inhibits complement dysregulation in vitro in C3 glomerulopathy. Immunobiology 220:8 (2015), 993–998.
    • (2015) Immunobiology , vol.220 , Issue.8 , pp. 993-998
    • Zhang, Y.1    Shao, D.2    Ricklin, D.3    Hilkin, B.M.4    Nester, C.M.5    Lambris, J.D.6    Smith, R.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.