Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation

Journal of Controlled Release

Volumn 243, Issue , 2016, Pages 160-171

  Yang, Zhaogang ^a   Xie, Jing ^b   Zhu, Jing ^c   Kang, Chen ^c   Chiang, Chiling ^d   Wang, Xinmei ^a   Wang, Xiaobing ^e,f   Kuang, Tairong ^a   Chen, Feng ^a   Chen, Zhou ^a   Zhang, Aili ^a   Yu, Bo ^a   Lee, Robert J ^c   Teng, Lesheng ^b   Lee, L James ^a  

^a Ohio State University   (United States)

^b JILIN UNIVERSITY   (China)

^c OHIO STATE UNIVERSITY   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e CANCER HOSPITAL   (China)

^f PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Electroporation; Endocytosis; Exosome; MCF 7; siRNA

Indexed keywords

GENE TRANSFER; MOLECULAR BIOLOGY; PORE SIZE;

ELECTROPORATION; ENDOCYTOSIS; EXOSOME; MCF-7; SIRNA;

DISEASES;

CD63 ANTIGEN; CD81 ANTIGEN; CD9 ANTIGEN; CLATHRIN; CYCLIN DEPENDENT KINASE 4; SMALL INTERFERING RNA; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; DOWN REGULATION; DRUG HALF LIFE; ELECTROPORATION; ENDOCYTOSIS; EXOSOME; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALIGNANT NEOPLASTIC DISEASE; MCF 7 CELL LINE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; TUMOR XENOGRAFT; WESTERN BLOTTING; ZETA POTENTIAL; ANIMAL; BAGG ALBINO MOUSE; BREAST TUMOR; EPITHELIUM CELL; GENE TRANSFER; GENETICS; MCF-7 CELL LINE; METABOLISM; NUDE MOUSE; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; ELECTROPORATION; ENDOCYTOSIS; EPITHELIAL CELLS; EXOSOMES; GENE TRANSFER TECHNIQUES; HUMANS; MCF-7 CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; PARTICLE SIZE; RNA, SMALL INTERFERING;

EID: 84991798433     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2016.10.008     Document Type: Article

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