Determination of key structure-activity relationships in siRNA delivery with a mixed micelle system

Journal of Controlled Release

Volumn 172, Issue 3, 2013, Pages 939-945

  Omedes Pujol, Marta ^a   Coleman, Daniel J L ^b   Allen, Christopher D ^b   Heidenreich, Olaf ^b   Fulton, David A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Gene knockdown; Leukaemia; Polymer micelles; siRNA; Structure activity relationships

Indexed keywords

BLOCK COPOLYMERS; CELL CULTURE; DISEASE CONTROL; GENES; RNA; SUSPENSIONS (FLUIDS);

GENE KNOCK DOWN; LEUKAEMIA; POLYMER MICELLES; SIRNA; STRUCTURE ACTIVITY RELATIONSHIPS;

MICELLES;

COPOLYMER; LUCIFERASE; NANOPARTICLE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX1;

ADHERENT CELL; ARTICLE; CANCER CELL CULTURE; CELL SUSPENSION; CONTROLLED STUDY; CYTOTOXICITY; FUSION GENE; GENE SILENCING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; LEUKEMIA CELL; MICELLE; ONCOGENE; ONCOGENE ETO; ONCOGENE RUNX1; PARTICLE SIZE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ACUTE MYELOID LEUKAEMIA; AML; FACS; FLUORESCENT ACTIVATED CELL SORTING; GENE KNOCKDOWN; LASER SCANNING CONFOCAL MICROSCOPY; LEUKAEMIA; LSCM; NILE RED; NR; P1; P2; PCL-B-PDMAEMA; PCL-B-PEG; PNP; POLYMER MICELLES; POLYMERIC NANOPARTICLE; SHORT INTERFERING RIBONUCLEIC ACID; SIRNA; STRUCTURE-ACTIVITY RELATIONSHIPS;

BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; DRUG CARRIERS; HUMANS; LEUKEMIA; MICELLES; NANOPARTICLES; POLYMERS; RNA INTERFERENCE; RNA, SMALL INTERFERING; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 84887202988     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.10.013     Document Type: Article

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