Attenuation of MIR-17∼92 cluster in bronchopulmonary dysplasia

Annals of the American Thoracic Society

Volumn 12, Issue 10, 2015, Pages 1506-1513

  Rogers, Lynette K ^a   Robbins, Mary ^b   Dakhlallah, Duaa ^b   Yang, Zhaogang ^c   Lee, L James ^c   Mikhail, Madison ^d   Nuovo, Gerard ^d   Pryhuber, Gloria S ^e   McGwin, Gerald ^f   Marsh, Clay B ^b   Tipple, Trent E ^g  

^a THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c The Ohio State University   (United States)

^d Phylogeny Inc   (United States)

^e UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^g University of Alabama at Birmingham   (United States)

Author keywords

Bronchopulmonary dysplasia; MicroRNA; MIR 17z92 cluster

Indexed keywords

DNA METHYLTRANSFERASE; LIPOPLEX; MICRORNA; MICRORNA 17 92; MICRORNA 20A; NANOPARTICLE; UNCLASSIFIED DRUG; MIRN17-92 MICRORNA, HUMAN;

ARTICLE; AUTOPSY; CONTROLLED STUDY; DNA METHYLATION; GENE CLUSTER; GENE EXPRESSION; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; HYPOXIC ISCHEMIC ENCEPHALOPATHY; LUNG DYSPLASIA; LUNG PARENCHYMA; MOLECULAR BEACON; MOLECULAR PATHOLOGY; NECROTIZING ENTEROCOLITIS; NEWBORN INTENSIVE CARE; PREMATURITY; PROMOTER REGION; RESPIRATORY DISTRESS SYNDROME; GENETICS; INFANT; LUNG; METABOLISM; NEWBORN; PATHOLOGY;

AUTOPSY; BRONCHOPULMONARY DYSPLASIA; DNA METHYLATION; DNA MODIFICATION METHYLASES; HUMANS; INFANT; INFANT, NEWBORN; INFANT, PREMATURE; LUNG; MICRORNAS; PROMOTER REGIONS, GENETIC;

EID: 84943630655     PISSN: 23256621     EISSN: None     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201501-058OC     Document Type: Article

References (40)

1. McLeod A, Ross P, Mitchell S, Tay D, Hunter L, Hall A, Paton J, Mutch L. Respiratory health in a total very low birthweight cohort and their classroom controls. Arch Dis Child 1996;74:188-194.
2. Thébaud B, Abman SH. Bronchopulmonary dysplasia: where have all the vessels gone? Roles of angiogenic growth factors in chronic lung disease. Am J Respir Crit Care Med 2007;175:978-985.
3. Thébaud B, Ladha F, Michelakis ED, Sawicka M, Thurston G, Eaton F, Hashimoto K, Harry G, Haromy A, Korbutt G, et al. Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxiainduced lung injury: evidence that angiogenesis participates in alveolarization. Circulation 2005;112:2477-2486.
4. Van Marter LJ. Epidemiology of bronchopulmonary dysplasia. Semin Fetal Neonatal Med 2009;14:358-366.
5. Wu S, Platteau A, Chen S, McNamara G, Whitsett J, Bancalari E. Conditional overexpression of connective tissue growth factor disrupts postnatal lung development. Am J Respir Cell Mol Biol 2010;42:552-563.
6. Ambalavanan N, Carlo WA. Bronchopulmonary dysplasia: new insights. Clin Perinatol 2004;31:613-628.
7. Dakhlallah D, Batte K, Wang Y, Cantemir-Stone CZ, Yan P, Nuovo G, Mikhail A, Hitchcock CL, Wright VP, Nana-Sinkam SP, et al. Epigenetic regulation of miR-17z92 contributes to the pathogenesis of pulmonary fibrosis. Am J Respir Crit Care Med 2013;187:397-405.
8. Bonauer A, Dimmeler S. The microRNA-17-92 cluster: still a miRacle? Cell Cycle 2009;8:3866-3873.
9. Morty RE, Königshoff M, Eickelberg O. Transforming growth factorbeta signaling across ages: from distorted lung development to chronic obstructive pulmonary disease. Proc Am Thorac Soc 2009;6: 607-613.
10. Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, Erkeland SJ, Newman J, Bronson RT, Crowley D, Stone JR, et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell 2008;132:875-886.
11. Nana-Sinkam SP, Karsies T, Riscili B, Ezzie M, Piper M. Lung microRNA: from development to disease. Expert Rev Respir Med 2009;3:373-385.
12. Lu Y, Thomson JM, Wong HY, Hammond SM, Hogan BL. Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol 2007;310:442-453.
13. Daniel FI, Cherubini K, Yurgel LS, de Figueiredo MA, Salum FG. The role of epigenetic transcription repression and DNA methyltransferases in cancer. Cancer 2011;117:677-687.
14. Robertson KD, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales FA, Jones PA. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res 1999;27: 2291-2298.
15. Tipple TE, Robbins M, Dakhlallah D, Rogers LK, Piper MG. MiR-17z92 cluster expression is decreased in bronchopulmonary dysplasia. Am J Respir Crit Care Med 2013;187:A5358.
16. Tipple TE, Robbins M, Rogers LK, Dakhlallah D, Piper MG. MiR-17z92 cluster expression is decreased in lungs from infants with bronchopulmonary dysplasia. Pediatric Academic Societies 2013; EPAS: 2825.2822.
17. Reynolds SD, Reynolds PR, Pryhuber GS, Finder JD, Stripp BR. Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways. Am J Respir Crit Care Med 2002;166:1498-1509.
18. Maniscalco WM, Watkins RH, OReilly MA, Shea CP. Increased epithelial cell proliferation in very premature baboons with chronic lung disease. Am J Physiol Lung Cell Mol Physiol 2002;283:L991-L1001.
19. Lee MK, Pryhuber GS, Schwarz MA, Smith SM, Pavlova Z, Sunday ME. Developmental regulation of p66Shc is altered by bronchopulmonary dysplasia in baboons and humans. Am J Respir Crit Care Med 2005;171:1384-1394.
20. Bhatt AJ, Pryhuber GS, Huyck H, Watkins RH, Metlay LA, Maniscalco WM. Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001;164:1971-1980.
21. Pryhuber GS, Huyck HL, Staversky RJ, Finkelstein JN, OReilly MA. Tumor necrosis factor-alpha-induced lung cell expression of antiapoptotic genes TRAF1 and cIAP2. Am J Respir Cell Mol Biol 2000;22:150-156.
22. Bhattacharya S, Go D, Krenitsky DL, Huyck HL, Solleti SK, Lunger VA, Metlay L, Srisuma S, Wert SE, Mariani TJ, et al. Genome-wide transcriptional profiling reveals connective tissue mast cell accumulation in bronchopulmonary dysplasia. Am J Respir Crit Care Med 2012;186:349-358.
23. Rogers LK, Young CM, Pennell ML, Tipple TE, Leonhart KL, Welty SE. Plasma lipid metabolites are associated with gestational age but not bronchopulmonary dysplasia. Acta Paediatr 2012;101:e321-e326.
24. Rogers LK, Graf AE, Bhatia A, Leonhart KL, Oza-Frank R. Associations between maternal and infant morbidities and sRAGE within the first week of life in extremely preterm infants. PLoS One 2013;8:e82537.
25. Nuovo GJ, Garofalo M, Valeri N, Roulstone V, Volinia S, Cohn DE, Phelps M, Harrington KJ, Vile R, Melcher A, et al. Reovirusassociated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples. Mod Pathol 2012;25:1333-1344.
26. Kwak KJ, Valincius G, Liao WC, Hu X, Wen X, Lee A, Yu B, Vanderah DJ, Lu W, Lee LJ. Formation and finite element analysis of tethered bilayer lipid structures. Langmuir 2010;26:18199-18208.
27. Wu Y, Kwak KJ, Agarwal K, Marras A, Wang C, Mao Y, Huang X, Ma J, Yu B, Lee R, et al. Detection of extracellular RNAs in cancer and viral infection via tethered cationic lipoplex nanoparticles containing molecular beacons. Anal Chem 2013;85:11265-11274.
28. Lu Y, Okubo T, Rawlins E, Hogan BL. Epithelial progenitor cells of the embryonic lung and the role of microRNAs in their proliferation. Proc Am Thorac Soc 2008;5:300-304.
29. Kotecha S, Wangoo A, Silverman M, Shaw RJ. Increase in the concentration of transforming growth factor beta-1 in bronchoalveolar lavage fluid before development of chronic lung disease of prematurity. J Pediatr 1996;128:464-469.
30. Lecart C, Cayabyab R, Buckley S, Morrison J, Kwong KY, Warburton D, Ramanathan R, Jones CA, Minoo P. Bioactive transforming growth factor-beta in the lungs of extremely low birthweight neonates predicts the need for home oxygen supplementation. Biol Neonate 2000;77:217-223.
31. Saito M, Ichiba H, Yokoi T, Hirai C, Yamano T, Kusuda S. Mitogenic activity of tracheal effluents from premature infants with chronic lung disease. Pediatr Res 2004;55:960-965.
32. Li L, Shi JY, Zhu GQ, Shi B. MiR-17-92 cluster regulates cell proliferation and collagen synthesis by targeting TGFB pathway in mouse palatal mesenchymal cells. J Cell Biochem 2012;113: 1235-1244.
33. Poitz DM, Augstein A, Gradehand C, Ende G, Schmeisser A, Strasser RH. Regulation of the Hif-system by micro-RNA 17 and 20a - role during monocyte-to-macrophage differentiation. Mol Immunol 2013;56:442-451.
34. Oeztuerk-Winder F, Guinot A, Ochalek A, Ventura JJ. Regulation of human lung alveolar multipotent cells by a novel p38a MAPK/miR-17-92 axis. EMBO J 2012;31:3431-3441.
35. Collins JJ, Thébaud B. Lung mesenchymal stromal cells in development and disease: to serve and protect? Antioxid Redox Signal 2014;21:1849-1862.
36. Zhang X, Xu J, Wang J, Gortner L, Zhang S, Wei X, Song J, Zhang Y, Li Q, Feng Z. Reduction of microRNA-206 contributes to the development of bronchopulmonary dysplasia through up-regulation of fibronectin 1. PLoS One 2013;8:e74750.
37. Yang Y, Qiu J, Kan Q, Zhou XG, Zhou XY. MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. Genet Mol Res 2013;12:5195-5206.
38. Cuna A, Halloran B, Faye-Petersen O, Kelly D, Crossman DK, Cui X, Pandit K, Kaminski N, Bhattacharya S, Ahmad A, et al. Alterations in gene expression and DNA Methylation during murine and human lung alveolar septation. Am J Respir Cell Mol Biol 2015;53: 60-73.
39. Wu YT, Chen WJ, Hsieh WS, Tsao PN, Yu SL, Lai CY, Lee WC, Jeng SF. MicroRNA expression aberration associated with bronchopulmonary dysplasia in preterm infants: a preliminary study. Respir Care 2013;58:1527-1535.
40. Bhandari A, Bhandari V. Pitfalls, problems, and progress in bronchopulmonary dysplasia. Pediatrics 2009;123:1562-1573.