Endothelin-1 induces proteinuria by heparanase-mediated disruption of the glomerular glycocalyx

Journal of the American Society of Nephrology

Volumn 27, Issue 12, 2016, Pages 3545-3551

  Garsen, Marjolein ^a   Lenoir, Olivia ^b   Rops, Angelique L W M M ^a   Dijkman, Henry B ^c   Willemsen, Brigith ^c   Van Kuppevelt, Toin H ^c   Rabelink, Ton J ^d   Berden, Jo H M ^a   Tharaux, Pierre Louis ^b   Van Der Vlag, Johan ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b PARIS CARDIOVASCULAR RESEARCH CENTER   (France)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; HEPARANASE; N ACETYL 3,3 DIPHENYL DEXTRO ALANYLLEUCYLASPARTYLISOLEUCYLISOLEUCYLTRYPTOPHAN; BETA GLUCURONIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL DISRUPTION; CELL STRUCTURE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; ELECTRIC RESISTANCE; GLOMERULAR GLYCOCALYX; GLYCOCALYX; KIDNEY FAILURE; MALE; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; PROTEINURIA; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANIMAL; DIABETIC NEPHROPATHIES; ENZYMOLOGY; GLOMERULUS; PHYSIOLOGY; ULTRASTRUCTURE;

ANIMALS; DIABETIC NEPHROPATHIES; ENDOTHELIN-1; GLUCURONIDASE; GLYCOCALYX; KIDNEY GLOMERULUS; MALE; MICE; PODOCYTES; PROTEINURIA;

EID: 84991797373     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2015091070     Document Type: Article

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