Cannabinoids prevent the amyloid β-induced activation of astroglial hemichannels: A neuroprotective mechanism

GLIA

Volumn 65, Issue 1, 2017, Pages 122-137

  Gajardo Gómez, Rosario ^a   Labra, Valeria C ^a   Maturana, Carola J ^a   Shoji, Kenji F ^b,c   Santibañez, Cristian A ^a   Sáez, Juan C ^b,c   Giaume, Christian ^d   Orellana, Juan A ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c Centro Interdisciplinario de Neurociencias de Valparaíso   (Chile)

^d CNRS   (France)

Author keywords

alzheimer; connexin43; glia; neuroinflammation; neuron

Indexed keywords

AMYLOID BETA PROTEIN; CONNEXIN 43; ENDOCANNABINOID; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; CANNABINOID; GAP JUNCTION PROTEIN; GLUTAMIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; AUTOCRINE EFFECT; CELL ACTIVATION; CELL COMMUNICATION; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RELEASE; ELECTRIC CONDUCTANCE; GAP JUNCTION; MEMBRANE CHANNEL; MEMBRANE CURRENT; MICROGLIA; MOUSE; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN INDUCTION; PYRAMIDAL NERVE CELL; ANIMAL; CELL CULTURE; CELL DEATH; DRUG EFFECTS; HIPPOCAMPUS; METABOLISM; NERVE CELL; NEWBORN;

AMYLOID BETA-PEPTIDES; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CANNABINOIDS; CELL DEATH; CELLS, CULTURED; CONNEXINS; GLUTAMIC ACID; HIPPOCAMPUS; MICE; NEURONS;

EID: 84991706314     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.23080     Document Type: Article

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