-
1
-
-
78751693154
-
Replication timing-related and gene bodyspecifi c methylation of active human genes
-
Aran D, Toperoff G, Rosenberg M, Hellman A (2011) Replication timing-related and gene bodyspecifi c methylation of active human genes. Hum Mol Genet 20(4):670-680. doi: 10.1093/hmg/ddq513
-
(2011)
Hum Mol Genet
, vol.20
, Issue.4
, pp. 670-680
-
-
Aran, D.1
Toperoff, G.2
Rosenberg, M.3
Hellman, A.4
-
2
-
-
84900448037
-
Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: Description of miRNA profi les at baseline
-
Ben-Dov IZ, Tan YC, Morozov P, Wilson PD, Rennert H, Blumenfeld JD, Tuschl T (2014) Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: description of miRNA profi les at baseline. PLoS One 9(1):e86856. doi: 10.1371/journal.pone.0086856
-
(2014)
Plos One
, vol.9
, Issue.1
-
-
Ben-Dov, I.Z.1
Tan, Y.C.2
Morozov, P.3
Wilson, P.D.4
Rennert, H.5
Blumenfeld, J.D.6
Tuschl, T.7
-
3
-
-
0033753779
-
The DNA methyltransferases of mammals
-
Bestor TH (2000) The DNA methyltransferases of mammals. Hum Mol Genet 9(16):2395-2402
-
(2000)
Hum Mol Genet
, vol.9
, Issue.16
, pp. 2395-2402
-
-
Bestor, T.H.1
-
4
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16(1):6-21. doi: 10.1101/gad.947102
-
(2002)
Genes Dev
, vol.16
, Issue.1
, pp. 6-21
-
-
Bird, A.1
-
5
-
-
76049128716
-
Chemical modifi er screen identifi es HDAC inhibitors as suppressors of PKD models
-
Cao Y, Semanchik N, Lee SH, Somlo S, Barbano PE, Coifman R, Sun Z (2009) Chemical modifi er screen identifi es HDAC inhibitors as suppressors of PKD models. Proc Natl Acad Sci U S A 106(51):21819-21824. doi: 10.1073/pnas.0911987106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.51
, pp. 21819-21824
-
-
Cao, Y.1
Semanchik, N.2
Lee, S.H.3
Somlo, S.4
Barbano, P.E.5
Coifman, R.6
Sun, Z.7
-
6
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specifi c patterns
-
Costello JF, Fruhwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomaki P, Lang JC, Schuller DE, Yu L, Bloomfi eld CD, Caligiuri MA, Yates A, Nishikawa R, Su Huang H, Petrelli NJ, Zhang X, O’Dorisio MS, Held WA, Cavenee WK, Plass C (2000) Aberrant CpG-island methylation has non-random and tumour-type-specifi c patterns. Nat Genet 24(2):132-138. doi: 10.1038/72785
-
(2000)
Nat Genet
, vol.24
, Issue.2
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
Wright, F.A.7
Feramisco, J.D.8
Peltomaki, P.9
Lang, J.C.10
Schuller, D.E.11
Yu, L.12
Bloomfi Eld, C.D.13
Caligiuri, M.A.14
Yates, A.15
Nishikawa, R.16
Su Huang, H.17
Petrelli, N.J.18
Zhang, X.19
O’Dorisio, M.S.20
Held, W.A.21
Cavenee, W.K.22
Plass, C.23
more..
-
7
-
-
79959872458
-
Cell typespecifi c DNA methylation at intragenic CpG islands in the immune system
-
Deaton AM, Webb S, Kerr AR, Illingworth RS, Guy J, Andrews R, Bird A (2011) Cell typespecifi c DNA methylation at intragenic CpG islands in the immune system. Genome Res 21(7):1074-1086. doi: 10.1101/gr.118703.110
-
(2011)
Genome Res
, vol.21
, Issue.7
, pp. 1074-1086
-
-
Deaton, A.M.1
Webb, S.2
Kerr, A.R.3
Illingworth, R.S.4
Guy, J.5
Rews, R.6
Bird, A.7
-
8
-
-
75149147806
-
Regulation of epidermal growth factor receptor traffi cking by lysine deacetylase HDAC6
-
Deribe YL, Wild P, Chandrashaker A, Curak J, Schmidt MH, Kalaidzidis Y, Milutinovic N, Kratchmarova I, Buerkle L, Fetchko MJ, Schmidt P, Kittanakom S, Brown KR, Jurisica I, Blagoev B, Zerial M, Stagljar I, Dikic I (2009) Regulation of epidermal growth factor receptor traffi cking by lysine deacetylase HDAC6. Sci Signal 2(102):ra84. doi: 10.1126/scisignal.2000576
-
(2009)
Sci Signal
, vol.2
, Issue.102
-
-
Deribe, Y.L.1
Wild, P.2
Chandrashaker, A.3
Curak, J.4
Schmidt, M.H.5
Kalaidzidis, Y.6
Milutinovic, N.7
Kratchmarova, I.8
Buerkle, L.9
Fetchko, M.J.10
Schmidt, P.11
Kittanakom, S.12
Brown, K.R.13
Jurisica, I.14
Blagoev, B.15
Zerial, M.16
Stagljar, I.17
Dikic, I.18
-
9
-
-
84872247653
-
Parallel analysis of mRNA and microRNA microarray profi les to explore functional regulatory patterns in polycystic kidney disease: Using PKD/Mhm rat model
-
Dweep H, Sticht C, Kharkar A, Pandey P, Gretz N (2013) Parallel analysis of mRNA and microRNA microarray profi les to explore functional regulatory patterns in polycystic kidney disease: using PKD/Mhm rat model. PLoS One 8(1):e53780. doi: 10.1371/journal.pone.0053780
-
(2013)
Plos One
, vol.8
, Issue.1
-
-
Dweep, H.1
Sticht, C.2
Kharkar, A.3
Pandey, P.4
Gretz, N.5
-
10
-
-
34248634004
-
Therapeutic potential for microRNAs
-
Esau CC, Monia BP (2007) Therapeutic potential for microRNAs. Adv Drug Deliv Rev 59(2-3):101-114. doi: 10.1016/j.addr.2007.03.007
-
(2007)
Adv Drug Deliv Rev
, vol.59
, Issue.2-3
, pp. 101-114
-
-
Esau, C.C.1
Monia, B.P.2
-
11
-
-
13844320649
-
Aberrant DNA methylation as a cancer-inducing mechanism
-
Esteller M (2005) Aberrant DNA methylation as a cancer-inducing mechanism. Annu Rev Pharmacol Toxicol 45:629-656. doi: 10.1146/annurev.pharmtox.45.120403.095832
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 629-656
-
-
Esteller, M.1
-
12
-
-
83655201373
-
Inhibition of histone deacetylases targets the transcription regulator Id2 to attenuate cystic epithelial cell proliferation
-
Fan LX, Li X, Magenheimer B, Calvet JP (2012) Inhibition of histone deacetylases targets the transcription regulator Id2 to attenuate cystic epithelial cell proliferation. Kidney Int 81(1):76-85. doi: 10.1038/ki.2011.296
-
(2012)
Kidney Int
, vol.81
, Issue.1
, pp. 76-85
-
-
Fan, L.X.1
Li, X.2
Magenheimer, B.3
Calvet, J.P.4
-
13
-
-
85015069067
-
Controlling the double helix
-
Felsenfeld G, Groudine M (2003) Controlling the double helix. Nature 421(6921):448-453. doi: 10.1038/nature01411
-
(2003)
Nature
, vol.421
, Issue.6921
, pp. 448-453
-
-
Felsenfeld, G.1
Groudine, M.2
-
14
-
-
5444227862
-
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach
-
Gius D, Cui H, Bradbury CM, Cook J, Smart DK, Zhao S, Young L, Brandenburg SA, Hu Y, Bisht KS, Ho AS, Mattson D, Sun L, Munson PJ, Chuang EY, Mitchell JB, Feinberg AP (2004) Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. Cancer Cell 6(4):361-371. doi: 10.1016/j.ccr.2004.08.029
-
(2004)
Cancer Cell
, vol.6
, Issue.4
, pp. 361-371
-
-
Gius, D.1
Cui, H.2
Bradbury, C.M.3
Cook, J.4
Smart, D.K.5
Zhao, S.6
Young, L.7
Brandenburg, S.A.8
Hu, Y.9
Bisht, K.S.10
Ho, A.S.11
Mattson, D.12
Sun, L.13
Munson, P.J.14
Chuang, E.Y.15
Mitchell, J.B.16
Feinberg, A.P.17
-
15
-
-
34250805982
-
MicroRNA targeting specifi city in mammals: Determinants beyond seed pairing
-
Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP (2007) MicroRNA targeting specifi city in mammals: determinants beyond seed pairing. Mol Cell 27(1):91-105. doi: 10.1016/j.molcel.2007.06.017
-
(2007)
Mol Cell
, vol.27
, Issue.1
, pp. 91-105
-
-
Grimson, A.1
Farh, K.K.2
Johnston, W.K.3
Garrett-Engele, P.4
Lim, L.P.5
Bartel, D.P.6
-
16
-
-
77949357100
-
Histone methylation regulates memory formation
-
Gupta S, Kim SY, Artis S, Molfese DL, Schumacher A, Sweatt JD, Paylor RE, Lubin FD (2010) Histone methylation regulates memory formation. J Neurosci Off J Soc Neurosci 30(10):3589-3599. doi: 10.1523/JNEUROSCI.3732-09.2010
-
(2010)
J Neurosci off J Soc Neurosci
, vol.30
, Issue.10
, pp. 3589-3599
-
-
Gupta, S.1
Kim, S.Y.2
Artis, S.3
Molfese, D.L.4
Schumacher, A.5
Sweatt, J.D.6
Paylor, R.E.7
Lubin, F.D.8
-
17
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman JG, Baylin SB (2003) Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349(21):2042-2054. doi: 10.1056/NEJMra023075
-
(2003)
N Engl J Med
, vol.349
, Issue.21
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
18
-
-
70350271175
-
Sequence features associated with microRNA strand selection in humans and fl ies
-
Hu HY, Yan Z, Xu Y, Hu H, Menzel C, Zhou YH, Chen W, Khaitovich P (2009) Sequence features associated with microRNA strand selection in humans and fl ies. BMC Genomics 10:413. doi: 10.1186/1471-2164-10-413
-
(2009)
BMC Genomics
, vol.10
, pp. 413
-
-
Hu, H.Y.1
Yan, Z.2
Xu, Y.3
Hu, H.4
Menzel, C.5
Zhou, Y.H.6
Chen, W.7
Khaitovich, P.8
-
19
-
-
38949212693
-
A novel CpG island set identifi es tissue-specifi c methylation at developmental gene loci
-
Illingworth R, Kerr A, Desousa D, Jorgensen H, Ellis P, Stalker J, Jackson D, Clee C, Plumb R, Rogers J, Humphray S, Cox T, Langford C, Bird A (2008) A novel CpG island set identifi es tissue-specifi c methylation at developmental gene loci. PLoS Biol 6(1):e22. doi: 10.1371/journal.pbio.0060022
-
(2008)
Plos Biol
, vol.6
, Issue.1
-
-
Illingworth, R.1
Kerr, A.2
Desousa, D.3
Jorgensen, H.4
Ellis, P.5
Stalker, J.6
Jackson, D.7
Clee, C.8
Plumb, R.9
Rogers, J.10
Humphray, S.11
Cox, T.12
Langford, C.13
Bird, A.14
-
20
-
-
0028151343
-
Toxicity of 5-aza-2′-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
-
Juttermann R, Li E, Jaenisch R (1994) Toxicity of 5-aza-2′-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc Natl Acad Sci U S A 91(25):11797-11801
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, Issue.25
, pp. 11797-11801
-
-
Juttermann, R.1
Li, E.2
Jaenisch, R.3
-
21
-
-
58849112575
-
Biogenesis of small RNAs in animals
-
Kim VN, Han J, Siomi MC (2009) Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol 10(2):126-139. doi: 10.1038/nrm2632
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.2
, pp. 126-139
-
-
Kim, V.N.1
Han, J.2
Siomi, M.C.3
-
22
-
-
33847076849
-
Chromatin modifi cations and their function
-
Kouzarides T (2007) Chromatin modifi cations and their function. Cell 128(4):693-705. doi: 10.1016/j.cell.2007.02.005
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 693-705
-
-
Kouzarides, T.1
-
23
-
-
28444469246
-
Silencing of microRNAs in vivo with ‘antagomirs’
-
Krutzfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, Stoffel M (2005) Silencing of microRNAs in vivo with ‘antagomirs’. Nature 438(7068):685-689. doi: 10.1038/nature04303
-
(2005)
Nature
, vol.438
, Issue.7068
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
Manoharan, M.6
Stoffel, M.7
-
24
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA hypomethylation
-
Laird PW, Jackson-Grusby L, Fazeli A, Dickinson SL, Jung WE, Li E, Weinberg RA, Jaenisch R (1995) Suppression of intestinal neoplasia by DNA hypomethylation. Cell 81(2):197-205
-
(1995)
Cell
, vol.81
, Issue.2
, pp. 197-205
-
-
Laird, P.W.1
Jackson-Grusby, L.2
Fazeli, A.3
Dickinson, S.L.4
Jung, W.E.5
Li, E.6
Weinberg, R.A.7
Jaenisch, R.8
-
25
-
-
85013170289
-
MicroRNA-21 aggravates cyst growth in a model of polycystic kidney disease
-
Lakhia R, Hajarnis S, Williams D, Aboudehen K, Yheskel M, Xing C, Hatley ME, Torres VE, Wallace DP, Patel V (2015) MicroRNA-21 aggravates cyst growth in a model of polycystic kidney disease. J Am Soc Nephrol JASN. doi: 10.1681/ASN.2015060634
-
(2015)
J am Soc Nephrol JASN
-
-
Lakhia, R.1
Hajarnis, S.2
Williams, D.3
Aboudehen, K.4
Yheskel, M.5
Xing, C.6
Hatley, M.E.7
Torres, V.E.8
Wallace, D.P.9
Patel, V.10
-
26
-
-
0027751663
-
The C. Elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75(5):843-854
-
(1993)
Cell
, vol.75
, Issue.5
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
27
-
-
55849085074
-
MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease
-
Lee SO, Masyuk T, Splinter P, Banales JM, Masyuk A, Stroope A, Larusso N (2008) MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease. J Clin Invest 118(11):3714-3724. doi: 10.1172/JCI34922
-
(2008)
J Clin Invest
, vol.118
, Issue.11
, pp. 3714-3724
-
-
Lee, S.O.1
Masyuk, T.2
Splinter, P.3
Banales, J.M.4
Masyuk, A.5
Stroope, A.6
Larusso, N.7
-
28
-
-
80052271347
-
Epigenetics and autosomal dominant polycystic kidney disease
-
Li X (2011) Epigenetics and autosomal dominant polycystic kidney disease. Biochim Biophys Acta 1812(10):1213-1218. doi: 10.1016/j.bbadis.2010.10.008
-
(2011)
Biochim Biophys Acta
, vol.1812
, Issue.10
, pp. 1213-1218
-
-
Li, X.1
-
29
-
-
34249003938
-
Principles and limitations of computational microRNA gene and target fi nding
-
Lindow M, Gorodkin J (2007) Principles and limitations of computational microRNA gene and target fi nding. DNA Cell Biol 26(5):339-351. doi: 10.1089/dna.2006.0551
-
(2007)
DNA Cell Biol
, vol.26
, Issue.5
, pp. 339-351
-
-
Lindow, M.1
Gorodkin, J.2
-
30
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, Tonti-Filippini J, Nery JR, Lee L, Ye Z, Ngo QM, Edsall L, Antosiewicz-Bourget J, Stewart R, Ruotti V, Millar AH, Thomson JA, Ren B, Ecker JR (2009) Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462(7271):315-322. doi: 10.1038/nature08514
-
(2009)
Nature
, vol.462
, Issue.7271
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
Hawkins, R.D.4
Hon, G.5
Tonti-Filippini, J.6
Nery, J.R.7
Lee, L.8
Ye, Z.9
Ngo, Q.M.10
Edsall, L.11
Antosiewicz-Bourget, J.12
Stewart, R.13
Ruotti, V.14
Millar, A.H.15
Thomson, J.A.16
Ren, B.17
Ecker, J.R.18
-
31
-
-
84869008969
-
HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic traffi cking and degradation in renal epithelial cells
-
Liu W, Fan LX, Zhou X, Sweeney WE Jr, Avner ED, Li X (2012) HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic traffi cking and degradation in renal epithelial cells. PLoS One 7(11):e49418. doi: 10.1371/journal.pone.0049418
-
(2012)
Plos One
, vol.7
, Issue.11
-
-
Liu, W.1
Fan, L.X.2
Zhou, X.3
Sweeney, W.E.4
Avner, E.D.5
Li, X.6
-
32
-
-
48749122914
-
Circulating microRNAs as stable blood-based markers for cancer detection
-
Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, Peterson A, Noteboom J, O’Briant KC, Allen A, Lin DW, Urban N, Drescher CW, Knudsen BS, Stirewalt DL, Gentleman R, Vessella RL, Nelson PS, Martin DB, Tewari M (2008) Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A 105(30):10513-10518. doi: 10.1073/pnas.0804549105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.30
, pp. 10513-10518
-
-
Mitchell, P.S.1
Parkin, R.K.2
Kroh, E.M.3
Fritz, B.R.4
Wyman, S.K.5
Pogosova-Agadjanyan, E.L.6
Peterson, A.7
Noteboom, J.8
O’Briant, K.C.9
Allen, A.10
Lin, D.W.11
Urban, N.12
Drescher, C.W.13
Knudsen, B.S.14
Stirewalt, D.L.15
Gentleman, R.16
Vessella, R.L.17
Nelson, P.S.18
Martin, D.B.19
Tewari, M.20
more..
-
33
-
-
34547920351
-
Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin
-
Nahhas F, Dryden SC, Abrams J, Tainsky MA (2007) Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin. Mol Cell Biochem 303(1-2):221-230. doi: 10.1007/s11010-007-9478-6
-
(2007)
Mol Cell Biochem
, vol.303
, Issue.1-2
, pp. 221-230
-
-
Nahhas, F.1
Dryden, S.C.2
Abrams, J.3
Tainsky, M.A.4
-
34
-
-
0037291214
-
The human Sir2 ortholog, SIRT2, is an NAD + -dependent tubulin deacetylase
-
North BJ, Marshall BL, Borra MT, Denu JM, Verdin E (2003) The human Sir2 ortholog, SIRT2, is an NAD + -dependent tubulin deacetylase. Mol Cell 11(2):437-444
-
(2003)
Mol Cell
, vol.11
, Issue.2
, pp. 437-444
-
-
North, B.J.1
Marshall, B.L.2
Borra, M.T.3
Denu, J.M.4
Verdin, E.5
-
36
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99(3):247-257
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
37
-
-
60749100351
-
Microarraybased approach identifi es microRNAs and their target functional patterns in polycystic kidney disease
-
Pandey P, Brors B, Srivastava PK, Bott A, Boehn SN, Groene HJ, Gretz N (2008) Microarraybased approach identifi es microRNAs and their target functional patterns in polycystic kidney disease. BMC Genomics 9:624. doi: 10.1186/1471-2164-9-624
-
(2008)
BMC Genomics
, vol.9
, pp. 624
-
-
Pandey, P.1
Brors, B.2
Srivastava, P.K.3
Bott, A.4
Boehn, S.N.5
Groene, H.J.6
Gretz, N.7
-
38
-
-
79955012441
-
Systems biology approach to identify transcriptomereprogramming and candidate microRNA targets during the progression of polycystic kidney disease
-
Pandey P, Qin S, Ho J, Zhou J, Kreidberg JA (2011) Systems biology approach to identify transcriptomereprogramming and candidate microRNA targets during the progression of polycystic kidney disease. BMC Syst Biol 5:56. doi: 10.1186/1752-0509-5-56
-
(2011)
BMC Syst Biol
, vol.5
, pp. 56
-
-
Pandey, P.1
Qin, S.2
Ho, J.3
Zhou, J.4
Kreidberg, J.A.5
-
39
-
-
62749161460
-
Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract
-
Pastorelli LM, Wells S, Fray M, Smith A, Hough T, Harfe BD, McManus MT, Smith L, Woolf AS, Cheeseman M, Greenfi eld A (2009) Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract. Mamm Genome Off J Int Mamm Genome Soc 20(3):140-151. doi: 10.1007/s00335-008-9169-y
-
(2009)
Mamm Genome off J Int Mamm Genome Soc
, vol.20
, Issue.3
, pp. 140-151
-
-
Pastorelli, L.M.1
Wells, S.2
Fray, M.3
Smith, A.4
Hough, T.5
Harfe, B.D.6
McManus, M.T.7
Smith, L.8
Woolf, A.S.9
Cheeseman, M.10
Greenfi Eld, A.11
-
40
-
-
84862118082
-
MicroRNAs and fi brosis
-
Patel V, Noureddine L (2012) MicroRNAs and fi brosis. Curr Opin Nephrol Hypertens 21(4):410-416. doi: 10.1097/MNH.0b013e328354e559
-
(2012)
Curr Opin Nephrol Hypertens
, vol.21
, Issue.4
, pp. 410-416
-
-
Patel, V.1
Noureddine, L.2
-
41
-
-
84870533401
-
MicroRNAs regulate renal tubule maturation through modulation of Pkd1
-
Patel V, Hajarnis S, Williams D, Hunter R, Huynh D, Igarashi P (2012) MicroRNAs regulate renal tubule maturation through modulation of Pkd1. J Am Soc Nephrol JASN 23(12):1941-1948. doi: 10.1681/ASN.2012030321
-
(2012)
J am Soc Nephrol JASN
, vol.23
, Issue.12
, pp. 1941-1948
-
-
Patel, V.1
Hajarnis, S.2
Williams, D.3
Hunter, R.4
Huynh, D.5
Igarashi, P.6
-
42
-
-
84879526558
-
MiR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease
-
Patel V, Williams D, Hajarnis S, Hunter R, Pontoglio M, Somlo S, Igarashi P (2013) miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. Proc Natl Acad Sci U S A 110(26):10765-10770. doi: 10.1073/pnas.1301693110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.26
, pp. 10765-10770
-
-
Patel, V.1
Williams, D.2
Hajarnis, S.3
Hunter, R.4
Pontoglio, M.5
Somlo, S.6
Igarashi, P.7
-
43
-
-
77957346763
-
Histone modifi cations and cancer
-
Sawan C, Herceg Z (2010) Histone modifi cations and cancer. Adv Genet 70:57-85. doi: 10.1016/B978-0-12-380866-0.60003-4
-
(2010)
Adv Genet
, vol.70
, pp. 57-85
-
-
Sawan, C.1
Herceg, Z.2
-
44
-
-
49949117302
-
Widespread changes in protein synthesis induced by microRNAs
-
Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, Rajewsky N (2008) Widespread changes in protein synthesis induced by microRNAs. Nature 455(7209):58-63. doi: 10.1038/nature07228
-
(2008)
Nature
, vol.455
, Issue.7209
, pp. 58-63
-
-
Selbach, M.1
Schwanhausser, B.2
Thierfelder, N.3
Fang, Z.4
Khanin, R.5
Rajewsky, N.6
-
45
-
-
78649383152
-
Cancer epigenetics
-
Taby R, Issa JP (2010) Cancer epigenetics. CA Cancer J Clin 60(6):376-392. doi: 10.3322/caac.20085
-
(2010)
CA Cancer J Clin
, vol.60
, Issue.6
, pp. 376-392
-
-
Taby, R.1
Issa, J.P.2
-
46
-
-
77950502479
-
The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity
-
Tran U, Zakin L, Schweickert A, Agrawal R, Doger R, Blum M, De Robertis EM, Wessely O (2010) The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity. Development 137(7):1107-1116. doi: 10.1242/dev.046045
-
(2010)
Development
, vol.137
, Issue.7
, pp. 1107-1116
-
-
Tran, U.1
Zakin, L.2
Schweickert, A.3
Agrawal, R.4
Doger, R.5
Blum, M.6
De Robertis, E.M.7
Wessely, O.8
-
47
-
-
33845973750
-
The polycystic kidney disease-1 gene is a target for p53-mediated transcriptional repression
-
Van Bodegom D, Saifudeen Z, Dipp S, Puri S, Magenheimer BS, Calvet JP, El-Dahr SS (2006) The polycystic kidney disease-1 gene is a target for p53-mediated transcriptional repression. J Biol Chem 281(42):31234-31244. doi: 10.1074/jbc.M606510200
-
(2006)
J Biol Chem
, vol.281
, Issue.42
, pp. 31234-31244
-
-
Van Bodegom, D.1
Saifudeen, Z.2
Dipp, S.3
Puri, S.4
Magenheimer, B.S.5
Calvet, J.P.6
El-Dahr, S.S.7
-
48
-
-
77953592497
-
Mechanisms of p53-mediated repression of the human polycystic kidney disease-1 promoter
-
van Bodegom D, Roessingh W, Pridjian A, El Dahr SS (2010) Mechanisms of p53-mediated repression of the human polycystic kidney disease-1 promoter. Biochim Biophys Acta 1799(7):502-509. doi: 10.1016/j.bbagrm.2010.04.001
-
(2010)
Biochim Biophys Acta
, vol.1799
, Issue.7
, pp. 502-509
-
-
Van Bodegom, D.1
Roessingh, W.2
Pridjian, A.3
El Dahr, S.S.4
-
49
-
-
78149484489
-
The microRNA spectrum in 12 body fl uids
-
Weber JA, Baxter DH, Zhang S, Huang DY, Huang KH, Lee MJ, Galas DJ, Wang K (2010) The microRNA spectrum in 12 body fl uids. Clin Chem 56(11):1733-1741. doi: 10.1373/clinchem.2010.147405
-
(2010)
Clin Chem
, vol.56
, Issue.11
, pp. 1733-1741
-
-
Weber, J.A.1
Baxter, D.H.2
Zhang, S.3
Huang, D.Y.4
Huang, K.H.5
Lee, M.J.6
Galas, D.J.7
Wang, K.8
-
50
-
-
84894477905
-
Genome-wide methylation profi ling of ADPKD identifi ed epigenetically regulated genes associated with renal cyst development
-
Woo YM, Bae JB, Oh YH, Lee YG, Lee MJ, Park EY, Choi JK, Lee S, Shin Y, Lyu J, Jung HY, Lee YS, Hwang YH, Kim YJ, Park JH (2014) Genome-wide methylation profi ling of ADPKD identifi ed epigenetically regulated genes associated with renal cyst development. Hum Genet 133(3):281-297. doi: 10.1007/s00439-013-1378-0
-
(2014)
Hum Genet
, vol.133
, Issue.3
, pp. 281-297
-
-
Woo, Y.M.1
Bae, J.B.2
Oh, Y.H.3
Lee, Y.G.4
Lee, M.J.5
Park, E.Y.6
Choi, J.K.7
Lee, S.8
Shin, Y.9
Lyu, J.10
Jung, H.Y.11
Lee, Y.S.12
Hwang, Y.H.13
Kim, Y.J.14
Park, J.H.15
-
51
-
-
84944384464
-
Epigenetic silencing of the MUPCDH gene as a possible prognostic biomarker for cystgrowth in ADPKD
-
Woo YM, Shin Y, Hwang JA, Hwang YH, Lee S, Park EY, Kong HK, Park HC, Lee YS, Park JH (2015) Epigenetic silencing of the MUPCDH gene as a possible prognostic biomarker for cystgrowth in ADPKD. Sci Rep 5:15238. doi: 10.1038/srep15238
-
(2015)
Sci Rep
, vol.5
, pp. 15238
-
-
Woo, Y.M.1
Shin, Y.2
Hwang, J.A.3
Hwang, Y.H.4
Lee, S.5
Park, E.Y.6
Kong, H.K.7
Park, H.C.8
Lee, Y.S.9
Park, J.H.10
-
52
-
-
77950496935
-
Polycystin-dependent fl uid fl ow sensing targets histone deacetylase 5 to prevent the development of renal cysts
-
Xia S, Li X, Johnson T, Seidel C, Wallace DP, Li R (2010) Polycystin-dependent fl uid fl ow sensing targets histone deacetylase 5 to prevent the development of renal cysts. Development 137(7):1075-1084. doi: 10.1242/dev.049437
-
(2010)
Development
, vol.137
, Issue.7
, pp. 1075-1084
-
-
Xia, S.1
Li, X.2
Johnson, T.3
Seidel, C.4
Wallace, D.P.5
Li, R.6
-
53
-
-
80052996141
-
Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants
-
Yang JS, Lai EC (2011) Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants. Mol Cell 43(6):892-903. doi: 10.1016/j.molcel.2011.07.024
-
(2011)
Mol Cell
, vol.43
, Issue.6
, pp. 892-903
-
-
Yang, J.S.1
Lai, E.C.2
-
54
-
-
33644856123
-
Epigenetic therapy of cancer: Past, present and future
-
Yoo CB, Jones PA (2006) Epigenetic therapy of cancer: past, present and future. Nat Rev Drug Discov 5(1):37-50. doi: 10.1038/nrd1930
-
(2006)
Nat Rev Drug Discov
, vol.5
, Issue.1
, pp. 37-50
-
-
Yoo, C.B.1
Jones, P.A.2
-
55
-
-
84863259319
-
Circulating microRNAs: A novel class of biomarkers to diagnose and monitor human cancers
-
Zen K, Zhang CY (2012) Circulating microRNAs: a novel class of biomarkers to diagnose and monitor human cancers. Med Res Rev 32(2):326-348. doi: 10.1002/med.20215
-
(2012)
Med Res Rev
, vol.32
, Issue.2
, pp. 326-348
-
-
Zen, K.1
Zhang, C.Y.2
-
56
-
-
0035883954
-
Transcription regulation by histone methylation: Interplay between different covalent modifi cations of the core histone tails
-
Zhang Y, Reinberg D (2001) Transcription regulation by histone methylation: interplay between different covalent modifi cations of the core histone tails. Genes Dev 15(18):2343-2360. doi: 10.1101/gad.927301
-
(2001)
Genes Dev
, vol.15
, Issue.18
, pp. 2343-2360
-
-
Zhang, Y.1
Reinberg, D.2
-
57
-
-
78650304236
-
Charting histone modifi cations and the functional organization of mammalian genomes
-
Zhou VW, Goren A, Bernstein BE (2011) Charting histone modifi cations and the functional organization of mammalian genomes. Nat Rev Genet 12(1):7-18. doi: 10.1038/nrg2905
-
(2011)
Nat Rev Genet
, vol.12
, Issue.1
, pp. 7-18
-
-
Zhou, V.W.1
Goren, A.2
Bernstein, B.E.3
-
58
-
-
84879637271
-
Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease
-
Zhou X, Fan LX, Sweeney WE Jr, Denu JM, Avner ED, Li X (2013) Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease. J Clin Invest 123(7):3084-3098.doi: 10.1172/JCI64401
-
(2013)
J Clin Invest
, vol.123
, Issue.7
, pp. 3084-3098
-
-
Zhou, X.1
Fan, L.X.2
Sweeney, W.E.3
Denu, J.M.4
Avner, E.D.5
Li, X.6
-
59
-
-
84894366738
-
SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplifi cation caused by loss of polycystin-1
-
Zhou X, Fan LX, Li K, Ramchandran R, Calvet JP, Li X (2014) SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplifi cation caused by loss of polycystin-1. Hum Mol Genet 23(6):1644-1655. doi: 10.1093/hmg/ddt556
-
(2014)
Hum Mol Genet
, vol.23
, Issue.6
, pp. 1644-1655
-
-
Zhou, X.1
Fan, L.X.2
Li, K.3
Ramchandran, R.4
Calvet, J.P.5
Li, X.6
-
60
-
-
84936759340
-
Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD
-
Zhou X, Fan LX, Peters DJ, Trudel M, Bradner JE, Li X (2015) Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD. Hum Mol Genet 24(14):3982-3993. doi: 10.1093/hmg/ddv136
-
(2015)
Hum Mol Genet
, vol.24
, Issue.14
, pp. 3982-3993
-
-
Zhou, X.1
Fan, L.X.2
Peters, D.J.3
Trudel, M.4
Bradner, J.E.5
Li, X.6
|