Insulin treatment prevents neuroinflammation and neuronal injury with restored neurobehavioral function in models of HIV/AIDS neurodegeneration

Journal of Neuroscience

Volumn 36, Issue 41, 2016, Pages 1683-1695

  Mamik, Manmeet K ^a   Asahchop, Eugene L ^a   Chan, Wing F ^a   Zhu, Yu ^a   Branton, William G ^a   McKenzie, Brienne A ^a   Cohen, Eric A ^b   Power, Christopher ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

FIV; HIV 1; Insulin; Microglia; Neuropathology; Neurotoxicity

Indexed keywords

GAG PROTEIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INSULIN; INSULIN RECEPTOR; INTERLEUKIN 6; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ANTIDIABETIC AGENT; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; NEUROPROTECTIVE AGENT;

ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAT; CONTROLLED STUDY; DECISION MAKING; ENZYME LINKED IMMUNOSORBENT ASSAY; FELINE IMMUNODEFICIENCY VIRUS; FEMALE; FLOW CYTOMETRY; GENE DOSAGE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HIPPOCAMPUS; HIV ASSOCIATED DEMENTIA; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SPATIAL MEMORY; VIRUS REPLICATION; AIDS DEMENTIA COMPLEX; ANIMAL; CELL DEATH; DRUG EFFECTS; GLIA; INTRANASAL DRUG ADMINISTRATION; LENTIVIRUS INFECTION; METABOLISM; NERVE CELL; NEURITIS; NEURODEGENERATIVE DISEASES; PATHOLOGY; PREGNANCY;

ADMINISTRATION, INTRANASAL; AIDS DEMENTIA COMPLEX; ANIMALS; CATS; CELL DEATH; FEMALE; HIV-1; HUMAN IMMUNODEFICIENCY VIRUS PROTEINS; HUMANS; HYPOGLYCEMIC AGENTS; IMMUNODEFICIENCY VIRUS, FELINE; INSULIN; LENTIVIRUS INFECTIONS; NEURITIS; NEURODEGENERATIVE DISEASES; NEUROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; PREGNANCY; RECEPTOR, INSULIN;

EID: 84991503339     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1287-16.2016     Document Type: Article

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