Neurovirulence depends on virus input titer in brain in feline immunodeficiency virus infection: Evidence for activation of innate immunity and neuronal injury

Journal of NeuroVirology

Volumn 8, Issue 5, 2002, Pages 420-431

  Johnston, J B ^a   Silva, C ^a   Hiebert, T ^b   Buist, R ^b   Dawood, M R ^b   Peeling, J ^b   Power, C ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Feline immunodeficiency virus; MR spectroscopy and imaging; Neurotoxicity; Neurovirulence; Viral titer

Indexed keywords

CD4 ANTIGEN; CREATINE; N ACETYLASPARTIC ACID; TISSUE EXTRACT; TRIMETHYLAMINE; ASPARTIC ACID; CHOLINE; DRUG DERIVATIVE; METHYLAMINE; N-ACETYLASPARTATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSAY; ASTROCYTOSIS; BRAIN INFECTION; CAT; CELL CULTURE; CEREBROSPINAL FLUID; COGNITIVE DEFECT; CONTROLLED STUDY; CULTURE MEDIUM; DIAGNOSTIC IMAGING; FELINE IMMUNODEFICIENCY VIRUS; FEMALE; FRONTAL CORTEX; HELPER CELL; IMMUNOREACTIVITY; IN VIVO STUDY; LENTIVIRINAE; LYMPHOCYTE DEPLETION; MACROPHAGE; MACROPHAGE ACTIVATION; NERVE CELL DIFFERENTIATION; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NEURORADIOLOGY; NEUROTOXICITY; NEUROTROPISM; NEWBORN; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SIGNAL PROCESSING; TISSUE CULTURE; VIRUS STRAIN; VIRUS VIRULENCE; WEIGHT GAIN; WHITE MATTER; ANIMAL; BRAIN; CAT DISEASE; CD4+ T LYMPHOCYTE; COMPARATIVE STUDY; DISEASE MODEL; GLIOSIS; IMMUNOLOGY; INNATE IMMUNITY; NERVE CELL; PATHOGENICITY; PATHOLOGY; VIROLOGY; VIRULENCE;

ANIMALIA; FELIDAE; FELINE IMMUNODEFICIENCY VIRUS; FELIS CATUS; LENTIVIRUS;

ANIMALS; ANIMALS, NEWBORN; ASPARTIC ACID; BRAIN; CATS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CHOLINE; CULTURE MEDIA, CONDITIONED; DISEASE MODELS, ANIMAL; FELINE ACQUIRED IMMUNODEFICIENCY SYNDROME; GLIOSIS; IMMUNITY, NATURAL; IMMUNODEFICIENCY VIRUS, FELINE; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; METHYLAMINES; NEURONS; VIRULENCE;

EID: 0036815972     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.1080/13550280260422721     Document Type: Article

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