A lipidomics approach in the characterization of zika-infected mosquito cells: Potential targets for breaking the transmission cycle

PLoS ONE

Volumn 11, Issue 10, 2016, Pages

  Melo, Carlos Fernando Odir Rodrigues ^a   De Oliveira, Diogo Noin ^a   De Oliveira Lima, Estela ^a   Guerreiro, Tatiane Melina ^a   Esteves, Cibele Zanardi ^a   Beck, Raissa Marques ^a   Padilla, Marina Aiello ^a   Milanez, Guilherme Paier ^a   Arns, Clarice Weis ^a   Proença Modena, José Luiz ^a   Souza Neto, Jayme Augusto ^b   Catharino, Rodrigo Ramos ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; LIPID; LIPIDOME; PHOSPHATIDIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLSERINE; PHOSPHOETHANOLAMINE; SPHINGOLIPID; TRIACYLGLYCEROL;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; INSECT CELL; LIPID ANALYSIS; LIPIDOMICS; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS IDENTIFICATION; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TRANSMISSION; ZIKA FEVER; ZIKA VIRUS; AEDES; ANIMAL; CELL LINE; FEMALE; HUMAN; LIPID METABOLISM; MALE; METABOLISM; PACIFIC ISLANDS; SOUTH AND CENTRAL AMERICA; TRANSMISSION; VIROLOGY; ZIKA VIRUS INFECTION;

AEDES; ANIMALS; CELL LINE; FEMALE; HUMANS; LATIN AMERICA; LIPID METABOLISM; MALE; OCEANIA; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 84991490715     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0164377     Document Type: Article

References (48)

1. Brunner M, Koskinen AM. Biology and Chemistry of Sphingosine-Related Metabolites. Current Organic Chemistry. 2004;8(17):1629-45. doi: 10.2174/1385272043369638
2. Chang C, Ortiz K, Ansari A, Gershwin ME. The Zika outbreak of the 21st century. Journal of autoimmunity. 2016;68:1-13. doi: 10.1016/j.jaut.2016.02.006 PMID: 26925496
3. Cao-Lormeau V-M, Blake A, Mons S, Lastère S, Roche C, Vanhomwegen J, et al. Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. The Lancet. 2016;387(10027):1531-9. doi: 10.1016/S0140-6736 (16) 00562-6 PMID: 26948433
4. Brasil P, Pereira J, Jose P, Raja Gabaglia C, Damasceno L, Wakimoto M, Ribeiro Nogueira RM, et al. Zika virus infection in pregnant women in Rio de Janeiro-preliminary report. New England Journal of Medicine. 2016. doi: 10.1056/NEJMoa1602412 PMID: 26943629
5. Faria NR, Da Silva Azevedo RdS, Kraemer MU, Souza R, Cunha MS, Hill SC, et al. Zika virus in the Americas: Early epidemiological and genetic findings. Science. 2016;352(6283):345-9. doi: 10.1126/science.aaf5036 PMID: 27013429
6. Lindenbach BD, Rice CM. Molecular biology of flaviviruses. Advances in virus research. 2003;59:23-62. doi: 10.1016/S0065-3527 (03) 59002-9 PMID: 14696326
7. Stiasny K, Koessl C, Heinz FX. Involvement of lipids in different steps of the flavivirus fusion mechanism. Journal of virology. 2003;77(14):7856-62. doi: 10.1128/JVI.77.14.7856-7862.2003 PMID: 12829825
8. Carnec X, Meertens L, Dejarnac O, Perera-Lecoin M, Hafirassou ML, Kitaura J, et al. The phosphatidylserine and phosphatidylethanolamine receptor CD300a binds dengue virus and enhances infection. Journal of virology. 2016;90(1):92-102. doi: 10.1128/JVI.01849-15 PMID: 26468529
9. Meertens L, Carnec X, Lecoin MP, Ramdasi R, Guivel-Benhassine F, Lew E, et al. The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry. Cell host & microbe. 2012;12(4):544-57. doi: 10.1016/j.chom.2012.08.009 PMID: 23084921
10. Moller-Tank S, Kondratowicz AS, Davey RA, Rennert PD, Maury W. Role of the phosphatidylserine receptor TIM-1 in enveloped-virus entry. Journal of virology. 2013;87(15):8327-41. doi: 10.1128/JVI. 01025-13 PMID: 23698310
11. Morizono K, Chen IS. Role of phosphatidylserine receptors in enveloped virus infection. Journal of virology. 2014;88(8):4275-90. doi: 10.1128/JVI.03287-13 PMID: 24478428
12. Morizono K, Xie Y, Olafsen T, Lee B, Dasgupta A, Wu AM, et al. The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry. Cell host & microbe. 2011;9(4):286-98. doi: 10.1016/j.chom.2011.03.012 PMID: 21501828
13. Richard AS, Zhang A, Park S-J, Farzan M, Zong M, Choe H. Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses. Proceedings of the National Academy of Sciences. 2015;112(47):14682-7. doi: 10.1073/pnas.1508095112 PMID: 26575624
14. Zhang J, Zhang Z, Chukkapalli V, Nchoutmboube JA, Li J, Randall G, et al. Positive-strand RNA viruses stimulate host phosphatidylcholine synthesis at viral replication sites. Proceedings of the National Academy of Sciences. 2016;113(8):E1064-E73. doi: 10.1073/pnas.1519730113 PMID: 26858414
15. Perera R, Riley C, Isaac G, Hopf-Jannasch AS, Moore RJ, Weitz KW, et al. Dengue virus infection perturbs lipid homeostasis in infected mosquito cells. PLoS Pathog. 2012;8(3):e1002584. doi: 10.1371/journal.ppat.1002584 PMID: 22457619
16. Barletta ABF, Alves LR, Silva MCLN, Sim S, Dimopoulos G, Liechocki S, et al. Emerging role of lipid droplets in Aedes aegypti immune response against bacteria and Dengue virus. Scientific reports. 2016;6. doi: 10.1038/srep19928 PMID: 26887863
17. Sánchez-Vargas I, Scott JC, Poole-Smith BK, Franz AW, Barbosa-Solomieu V, Wilusz J, et al. Dengue virus type 2 infections of Aedes aegypti are modulated by the mosquito's RNA interference pathway. PLoS Pathog. 2009;5(2):e1000299. doi: 10.1371/journal.ppat.1000299 PMID: 19214215
18. Souza-Neto JA, Sim S, Dimopoulos G. An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense. Proceedings of the National Academy of Sciences. 2009;106(42):17841-6. doi: 10.1073/pnas.0905006106 PMID: 19805194
19. Xi Z, Ramirez JL, Dimopoulos G. The Aedes aegypti toll pathway controls dengue virus infection. PLoS Pathog. 2008;4(7):e1000098. doi: 10.1371/journal.ppat.1000098 PMID: 18604274
20. Fauci AS, Morens DM. Zika Virus in the Americas-Yet Another Arbovirus Threat. New England Journal of Medicine. 2016. doi: 10.1056/NEJMp1600297 PMID: 26761185
21. Ginier M, Neumayr A, Günther S, Schmidt-Chanasit J, Blum J. Zika without symptoms in returning travellers: What are the implications? Travel medicine and infectious disease. 2016;14(1):16-20. doi: 10.1016/j.tmaid.2016.01.012 PMID: 26876061
22. Sessions OM, Barrows NJ, Souza-Neto JA, Robinson TJ, Hershey CL, Rodgers MA, et al. Discovery of insect and human dengue virus host factors. Nature. 2009;458(7241):1047-50. doi: 10.1038/nature07967 PMID: 19396146
23. Gliedman JB, Smith JF, Brown D. Morphogenesis of Sindbis virus in cultured Aedes albopictus cells. Journal of virology. 1975;16(4):913-26. PMID: 170422
24. Hematian A, Sadeghifard N, Mohebi R, Taherikalani M, Nasrolahi A, Amraei M, et al. Traditional and Modern Cell Culture in Virus Diagnosis. Osong public health and research perspectives. 2016;7(2):77-82. doi: 10.1016/j.phrp. 2015.11.011 PMID: 27169004
25. Lanciotti RS, Kosoy OL, Laven JJ, Velez JO, Lambert AJ, Johnson AJ, et al. Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007. Emerg Infect Dis. 2008;14(8):1232-9. doi: 10.3201/eid1408.080287 PMID: 18680646
26. De Oliveira DN, De Bona Sartor S, Ferreira MS, Catharino RR. Cosmetic analysis using matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI). Materials. 2013;6(3):1000-10. doi: 10.3390/ma6031000
27. Xia J, Sinelnikov IV, Han B, Wishart DS. MetaboAnalyst 3.0-making metabolomics more meaningful. Nucleic acids research. 2015;43(W1):W251-W7. doi: 10.1093/nar/gkv380 PMID: 25897128
28. Gibellini F, Smith TK. The Kennedy pathway-de novo synthesis of phosphatidylethanolamine and phosphatidylcholine. IUBMB life. 2010;62(6):414-28. doi: 10.1002/iub.337 PMID: 20503434
29. Amemiya F, Maekawa S, Itakura Y, Kanayama A, Matsui A, Takano S, et al. Targeting lipid metabolism in the treatment of hepatitis C virus infection. Journal of Infectious Diseases. 2008;197(3):361-70. doi: 10.1086/525287 PMID: 18248300
30. Soulages JL, Wu Z, Firdaus SJ, Mahalingam R, Arrese EL. Monoacylglycerol and diacylglycerol acyltransferases and the synthesis of neutral glycerides in Manduca sexta. Insect biochemistry and molecular biology. 2015;62:194-210. doi: 10.1016/j.ibmb.2014.09.007 PMID: 25263765
31. Umehara T, Sudoh M, Yasui F, Matsuda C, Hayashi Y, Chayama K, et al. Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model. Biochemical and biophysical research communications. 2006;346(1):67-73. doi: 10.1016/j.bbrc.2006.05.085 PMID: 16750511
32. Carocci M, Hinshaw SM, Rodgers MA, Villareal VA, Burri DJ, Pilankatta R, et al. The bioactive lipid 4-hydroxyphenyl retinamide inhibits flavivirus replication. Antimicrobial agents and chemotherapy. 2015;59(1):85-95. doi: 10.1128/AAC.04177-14 PMID: 25313218
33. Balasubramanian K, Schroit AJ. Aminophospholipid asymmetry: a matter of life and death. Annual review of physiology. 2003;65(1):701-34. doi: 10.1146/annurev. physiol.65.092101.142459 PMID: 12471163
34. Zwaal RF, Schroit AJ. Pathophysiologic implications of membrane phospholipid asymmetry in blood cells. Blood. 1997;89(4):1121-32. PMID: 9028933
35. Fadok VA, Bratton DL, Frasch SC, Warner ML, Henson PM. The role of phosphatidylserine in recognition of apoptotic cells by phagocytes. Cell death and differentiation. 1998;5(7):551-62. doi: 10.1038/sj.cdd.4400404 PMID: 10200509
36. Lee S-H, Meng XW, Flatten KS, Loegering DA, Kaufmann SH. Phosphatidylserine exposure during apoptosis reflects bidirectional trafficking between plasma membrane and cytoplasm. Cell Death & Differentiation. 2013;20(1):64-76. doi: 10.1038/cdd.2012.93 PMID: 22858544
37. Barathan M, Gopal K, Mohamed R, Ellegård R, Saeidi A, Vadivelu J, et al. Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes. Apoptosis. 2015;20(4):466-80. doi: 10.1007/s10495-014-1084-y PMID: 25577277
38. Mercer J, Helenius A. Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cells. Science. 2008;320(5875):531-5. doi: 10.1126/science.1155164 PMID: 18436786
39. Soares MM, King SW, Thorpe PE. Targeting inside-out phosphatidylserine as a therapeutic strategy for viral diseases. Nature medicine. 2008;14(12):1357-62. doi: 10.1038/nm.1885 PMID: 19029986
40. Takizawa T, Matsukawa S, Higuchi Y, Nakamura S, Nakanishi Y, Fukuda R. Induction of programmed cell death (apoptosis) by influenza virus infection in tissue culture cells. Journal of General Virology. 1993;74(11):2347-55. doi: 10.1099/0022-1317-74-11-2347 PMID: 7504071
41. Miner JJ, Daniels BP, Shrestha B, Proenca-Modena JL, Lew ED, Lazear HM, et al. The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity. Nature medicine. 2015;21(12):1464-72. doi: 10.1038/nm.3974 PMID: 26523970
42. Trotter PJ, Voelker DR. Identification of a non-mitochondrial phosphatidylserine decarboxylase activity (PSD2) in the yeast Saccharomyces cerevisiae. Journal of Biological Chemistry. 1995;270(11):6062-70. PMID: 7890739
43. Zinser E, Sperka-Gottlieb C, Fasch E-V, Kohlwein SD, Paltauf F, Daum G. Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae. Journal of bacteriology. 1991;173(6):2026-34. PMID: 2002005
44. Maulik N, Kagan VE, Tyurin VA, Das DK. Redistribution of phosphatidylethanolamine and phosphatidylserine precedes reperfusion-induced apoptosis. American Journal of Physiology-Heart and Circulatory Physiology. 1998;274(1):H242-H8. PMID: 9458873
45. Verkleij A, Leunissen-Bijvelt J, De Kruijff B, Mt Hope, Cullis P, editors. Non-Bilayer Structures in Membrane Fusion. Ciba Foundation Symposium 103-Cell Fusion; 1984: Wiley Online Library.
46. Liang T, Su W, Zhang Q, Li G, Gao S, Lou J, et al. Roles of Sphincter of Oddi Laxity in Bile Duct Microenvironment in Patients with Cholangiolithiasis: From the Perspective of the Microbiome and Metabolome. Journal of the American College of Surgeons. 2015. doi: 10.1016/j.jamcollsurg.2015.12.009 PMID: 26922601
47. To KK, Lee K-C, Wong SS, Lo K-C, Lui Y-M, Jahan AS, et al. Lipid mediators of inflammation as novel plasma biomarkers to identify patients with bacteremia. Journal of Infection. 2015;70(5):433-44. doi: 10.1016/j.jinf.2015.02.011 PMID: 25727996
48. Boumann HA, De Kruijff B, Heck AJ, De Kroon AI. The selective utilization of substrates in vivo by the phosphatidylethanolamine and phosphatidylcholine biosynthetic enzymes Ept1p and Cpt1p in yeast. FEBS letters. 2004;569(1):173-7. doi: 10.1016/j.febslet.2004.05.043 PMID: 15225629