The phosphatidylserine and phosphatidylethanolamine receptor CD300a binds dengue virus and enhances infection

Journal of Virology

Volumn 90, Issue 1, 2016, Pages 92-102

  Carnec, Xavier ^a,b,c   Meertens, Laurent ^a,b,c   Dejarnac, Ophélie ^a,b,c   Perera Lecoin, Manuel ^a,b,c   Hafirassou, Mohamed Lamine ^a,b,c   Kitaura, Jiro ^d   Ramdasi, Rasika ^a,b,c   Schwartz, Olivier ^e   Amara, Ali ^a,b,c  

^a SAINT LOUIS HOSPITAL   (France)

^b UNIVERSITÉ PARIS DIDEROT   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d UNIVERSITY OF TOKYO   (Japan)

^e INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD300A RECEPTOR; CD300A RECEPTOR ANTIBODY; CLATHRIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN V; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLETHANOLAMINE RECEPTOR; PHOSPHATIDYLSERINE; POLYCLONAL ANTIBODY; RECEPTOR; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG; CD300A PROTEIN, HUMAN; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; PROTEIN BINDING; VIRUS RECEPTOR;

ANIMAL CELL; ARTICLE; CELL SURFACE; CHIKUNGUNYA VIRUS; CONTROLLED STUDY; DENGUE; DENGUE VIRUS; ENDOCYTOSIS; HUMAN; HUMAN CELL; INTERNALIZATION; MACROPHAGE; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; RECEPTOR BINDING; SEROTYPE; VIRION; VIRUS CELL INTERACTION; VIRUS ENTRY; VIRUS PARTICLE; VIRUS PATHOGENESIS; WEST NILE VIRUS; CELL LINE; CHEMISTRY; HOST PATHOGEN INTERACTION; METABOLISM; PHYSIOLOGY;

ANTIGENS, CD; CELL LINE; CHIKUNGUNYA VIRUS; DENGUE VIRUS; ENDOCYTOSIS; HOST-PATHOGEN INTERACTIONS; HUMANS; MACROPHAGES; MEMBRANE PROTEINS; PHOSPHATIDYLETHANOLAMINES; PHOSPHATIDYLSERINES; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; RECEPTORS, VIRUS; VIRUS INTERNALIZATION; WEST NILE VIRUS;

EID: 84953897925     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01849-15     Document Type: Article

References (34)

1. Gould EA, Solomon T. 2008. Pathogenic flaviviruses. Lancet 371:500-509. http://dx.doi.org/10.1016/S0140-6736(08)60238-X.
2. Gubler DJ, Kuno G, MarkoffL. 2007. Flaviviruses, p 1153-1252. In Knipe DM, Howley PM (ed), Fields virology, 5th ed. Lippincott/The Williams & Wilkins Co, Philadelphia, PA.
3. Halstead SB. 2007. Dengue. Lancet 370:1644-1652. http://dx.doi.org/10.1016/S0140-6736(07)61687-0.
4. Kyle JL, Harris E. 2008. Global spread and persistence of dengue. Annu Rev Microbiol 62:71-92. http://dx.doi.org/10.1146/annurev.micro.62.081307.163005.
5. Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, Drake JM, Brownstein JS, Hoen AG, Sankoh O, Myers MF, George DB, Jaenisch T, Wint GR, Simmons CP, Scott TW, Farrar JJ, Hay SI. 2013. The global distribution and burden of dengue. Nature 496:504-507. http://dx.doi.org/10.1038/nature12060.
6. Perera-Lecoin M, Meertens L, Carnec X, Amara A. 2014. Flavivirus entry receptors: an update. Viruses 6:69-88.
7. Chen Y, Maguire T, Hileman RE, Fromm JR, Esko JD, Linhardt RJ, Marks RM. 1997. Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate. Nat Med 3:866-871. http://dx.doi.org/10.1038/nm0897-866.
8. Lozach PY, Burleigh L, Staropoli I, Navarro-Sanchez E, Harriague J, Virelizier JL, Rey FA, Despres P, Arenzana-Seisdedos F, Amara A. 2005. Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals. J Biol Chem 280:23698-23708. http://dx.doi.org/10.1074/jbc. M504337200.
9. Miller JL, de Wet BJ, Martinez-Pomares L, Radcliffe CM, Dwek RA, Rudd PM, Gordon S. 2008. The mannose receptor mediates dengue virus infection of macrophages. PLoS Pathog 4:e17. http://dx.doi.org/10.1371/journal.ppat.0040017.
10. Tassaneetrithep B, Burgess TH, Granelli-Piperno A, Trumpfheller C, Finke J, Sun W, Eller MA, Pattanapanyasat K, Sarasombath S, Birx DL, Steinman RM, Schlesinger S, Marovich MA. 2003. DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells. J Exp Med 197: 823-829. http://dx.doi.org/10.1084/jem.20021840.
11. Navarro-Sanchez E, Altmeyer R, Amara A, Schwartz O, Fieschi F, Virelizier JL, Arenzana-Seisdedos F, Despres P. 2003. Dendritic-cellspecific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses. EMBO Rep 4:723-728. http://dx.doi.org/10.1038/sj.embor.embor866.
12. Meertens L, Carnec X, Lecoin MP, Ramdasi R, Guivel-Benhassine F, Lew E, Lemke G, Schwartz O, Amara A. 2012. The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry. Cell Host Microbe 12:544-557. http://dx.doi.org/10.1016/j.chom.2012.08.009.
13. Lemke G, Rothlin CV. 2008. Immunobiology of the TAM receptors. Nat Rev Immunol 8:327-336. http://dx.doi.org/10.1038/nri2303.
14. Freeman GJ, Casasnovas JM, Umetsu DT, DeKruyffRH. 2010. TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol Rev 235:172-189. http://dx.doi.org/10.1111/j.0105-2896.2010.00903.x.
15. Ravichandran KS. 2011. Beginnings of a good apoptotic meal: the findme and eat-me signaling pathways. Immunity 35:445-455. http://dx.doi.org/10.1016/j.immuni.2011.09.004.
16. Santiago C, Ballesteros A, Martinez-Munoz L, Mellado M, Kaplan GG, Freeman GJ, Casasnovas JM. 2007. Structures of T cell immunoglobulin mucin protein 4 show a metal-ion-dependent ligand binding site where phosphatidylserine binds. Immunity 27:941-951. http://dx.doi.org/10.1016/j.immuni.2007.11.008.
17. Miyanishi M, Tada K, Koike M, Uchiyama Y, Kitamura T, Nagata S. 2007. Identification of Tim4 as a phosphatidylserine receptor. Nature 450: 435-439. http://dx.doi.org/10.1038/nature06307.
18. Linger RM, Keating AK, Earp HS, Graham DK. 2008. TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer. Adv Cancer Res 100:35-83. http://dx.doi.org/10.1016/S0065-230X(08)00002-X.
19. Amara A, Mercer J. 2015. Viral apoptotic mimicry. Nat Rev Microbiol 13:461-469. http://dx.doi.org/10.1038/nrmicro3469.
20. Hamel R, Dejarnac O, Wichit S, Ekchariyawat P, Neyret A, Luplertlop N, Perera-Lecoin M, Surasombatpattana P, Talignani L, Thomas F, Cao-Lormeau VM, Choumet V, Briant L, Despres P, Amara A, Yssel H, Misse D. 2015. Biology of Zika virus infection in human skin cells. J Virol 89:8880-8896. http://dx.doi.org/10.1128/JVI.00354-15.
21. Borrego F. 2013. The CD300 molecules: an emerging family of regulators of the immune system. Blood 121:1951-1960. http://dx.doi.org/10.1182/blood-2012-09-435057.
22. Saleh R, Wedeh G, Herrmann H, Bibi S, Cerny-Reiterer S, Sadovnik I, Blatt K, Hadzijusufovic E, Jeanningros S, Blanc C, Legarff-Tavernier M, Chapiro E, Nguyen-Khac F, Subra F, Bonnemye P, Dubreuil P, Desplat V, Merle-Beral H, Willmann M, Rulicke T, Valent P, Arock M. 2014. A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection. Blood 124:111-120. http://dx.doi.org/10.1182/blood-2013-10-534685.
23. Fernandez-Garcia MD, Meertens L, Bonazzi M, Cossart P, Arenzana-Seisdedos F, Amara A. 2011. Appraising the roles of CBLL1 and the ubiquitin/proteasome system for flavivirus entry and replication. J Virol 85:2980-2989. http://dx.doi.org/10.1128/JVI.02483-10.
24. Krishnan MN, Sukumaran B, Pal U, Agaisse H, Murray JL, Hodge TW, Fikrig E. 2007. Rab5 is required for the cellular entry of dengue and West Nile viruses. J Virol 81:4881-4885. http://dx.doi.org/10.1128/JVI.02210-06.
25. van der Schaar HM, Rust MJ, Chen C, van der Ende-Metselaar H, Wilschut J, Zhuang X, Smit JM. 2008. Dissecting the cell entry pathway of dengue virus by single-particle tracking in living cells. PLoS Pathog 4:e1000244. http://dx.doi.org/10.1371/journal.ppat.1000244.
26. Benmerah A, Bayrou M, Cerf-Bensussan N, Dautry-Varsat A. 1999. Inhibition of clathrin-coated pit assembly by an Eps15 mutant. J Cell Sci 112(Pt 9):1303-1311.
27. Zenarruzabeitia O, Vitalle J, Eguizabal C, Simhadri VR, Borrego F. 2015. The biology and disease relevance of CD300a, an inhibitory receptor for phosphatidylserine and phosphatidylethanolamine. J Immunol 194: 5053-5060. http://dx.doi.org/10.4049/jimmunol.1500304.
28. Nakahashi-Oda C, Tahara-Hanaoka S, Honda S, Shibuya K, Shibuya A. 2012. Identification of phosphatidylserine as a ligand for the CD300a immunoreceptor. Biochem Biophys Res Commun 417:646-650. http://dx.doi.org/10.1016/j.bbrc.2011.12.025.
29. Simhadri VR, Andersen JF, Calvo E, Choi SC, Coligan JE, Borrego F. 2012. Human CD300a binds to phosphatidylethanolamine and phosphatidylserine, and modulates the phagocytosis of dead cells. Blood 119: 2799-2809. http://dx.doi.org/10.1182/blood-2011-08-372425.
30. Nakahashi-Oda C, Tahara-Hanaoka S, Shoji M, Okoshi Y, Nakano-Yokomizo T, Ohkohchi N, Yasui T, Kikutani H, Honda S, Shibuya K, Nagata S, Shibuya A. 2012. Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor. J Exp Med 209:1493-1503. http://dx.doi.org/10.1084/jem.20120096.
31. Zhao M, Li Z, Bugenhagen S. 2008. 99mTc-labeled duramycin as a novel phosphatidylethanolamine-binding molecular probe. J Nucl Med 49: 1345-1352. http://dx.doi.org/10.2967/jnumed.107.048603.
32. Leventis PA, Grinstein S. 2010. The distribution and function of phosphatidylserine in cellular membranes. Annu Rev Biophys 39:407-427. http://dx.doi.org/10.1146/annurev.biophys.093008.131234.
33. Morizono K, Chen IS. 2014. Role of phosphatidylserine receptors in enveloped virus infection. J Virol 88:4275-4290. http://dx.doi.org/10.1128/JVI.03287-13.
34. Kim EJ, Lee SM, Suk K, Lee WH. 2012. CD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signaling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell lines. Immunology 135:226-235. http://dx.doi.org/10.1111/j.1365-2567.2011.03528.x.