Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

Human Molecular Genetics

Volumn 25, Issue 9, 2016, Pages 1803-1813

  Kanekura, Kohsuke ^a,b   Yagi, Takuya ^a   Cammack, Alexander J ^a   Mahadevan, Jana ^a   Kuroda, Masahiko ^b   Harms, Matthew B ^c   Miller, Timothy M ^a   Urano, Fumihiko ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

^c Columbia University College of Physicians and Surgeon ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; BINDING PROTEIN; DIPEPTIDE DERIVATIVE; GLYCINE; INITIATION FACTOR; PROLINE; C9ORF72 PROTEIN, HUMAN; DIPEPTIDE; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN GROUP A B; HNRNP A1; PROTEIN; REPETITIVE DNA;

ANIMAL CELL; ARTICLE; CHROMOSOME 9; COMPLEX FORMATION; CONTROLLED STUDY; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE REPEAT; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; PROTEOMICS; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL; BRAIN; CASE CONTROL STUDY; CELL CULTURE; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MOTONEURON; MOUSE; PATHOLOGY; PROTEIN SYNTHESIS;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BRAIN; CASE-CONTROL STUDIES; CELLS, CULTURED; DIPEPTIDES; DNA REPEAT EXPANSION; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP A-B; HUMANS; MICE; MOTOR NEURONS; PROTEIN BIOSYNTHESIS; PROTEINS;

EID: 84991396645     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddw052     Document Type: Article

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