NF1 germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1

Human Molecular Genetics

Volumn 25, Issue 9, 2016, Pages 1703-1713

  Toonen, Joseph A ^a   Anastasaki, Corina ^a   Smithson, Laura J ^a   Gianino, Scott M ^a   Li, Kairong ^b   Kesterson, Robert A ^b   Gutmann, David H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; NEOMYCIN; NEUROFIBROMIN; PROTEIN KINASE B; RANTES; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRDU ASSAY; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENETICALLY ENGINEERED MOUSE STRAIN; GERMLINE MUTATION; KNOCKOUT MOUSE; MICROGLIA; MOUSE; MUTATIONAL ANALYSIS; NERVE CELL NECROSIS; NEUROFIBROMATOSIS TYPE 1; NONHUMAN; OPTIC NERVE; OPTIC NERVE GLIOMA; PARACRINE SIGNALING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA GANGLION CELL; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR GENE; ANIMAL; C57BL MOUSE; CELL CULTURE; COMPLICATION; DISEASE MODEL; FEMALE; GENETICS; MALE; METABOLISM; PATHOLOGY;

ANIMALS; ASTROCYTES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; GERM-LINE MUTATION; GLIAL FIBRILLARY ACIDIC PROTEIN; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NEUROFIBROMATOSIS 1; NEUROFIBROMIN 1; OPTIC NERVE; OPTIC NERVE GLIOMA;

EID: 84991363482     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddw039     Document Type: Article

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