Detection of drug-induced acute kidney injury in humans using urinary KIM-1, miR-21, -200c, and -423

Toxicological Sciences

Volumn 152, Issue 1, 2016, Pages 205-213

  Pavkovic, Mira ^a,e   Robinson Cohen, Cassianne ^b   Chua, Alicia S ^c   Nicoara, Oana ^d   Cárdenas González, Mariana ^a   Bijol, Vanesa ^e   Ramachandran, Krithika ^e   Hampson, Lucy ^f   Pirmohamed, Munir ^f   Antoine, Daniel J ^f   Frendl, Gyorgy ^e   Himmelfarb, Jonathan ^b   Waikar, Sushrut S ^e   Vaidya, Vishal S ^a,e,g  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f UNIVERSITY OF LIVERPOOL   (United Kingdom)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Acute kidney injury; Biomarker; KIM 1; MicroRNAs; Nephrotoxicity in patients

Indexed keywords

BIOLOGICAL MARKER; CISPLATIN; CREATININE; KIDNEY INJURY MOLECULE 1; MESSENGER RNA; MICRORNA; MICRORNA 200C; MICRORNA 21; MICRORNA 423; PARACETAMOL; UNCLASSIFIED DRUG; HAVCR1 PROTEIN, HUMAN; MIRN200 MICRORNA, HUMAN; MIRN21 MICRORNA, HUMAN; MIRN423 MICRORNA, HUMAN;

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; CELL CULTURE; CLINICAL EVALUATION; COHORT ANALYSIS; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CROSS-SECTIONAL STUDY; DRUG INDUCED DISEASE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; KIDNEY TUBULE CELL; KIDNEY TUBULE EPITHELIUM; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MESOTHELIOMA; RECEIVER OPERATING CHARACTERISTIC; SINGLE BLIND PROCEDURE; STATISTICAL ANALYSIS; URINE LEVEL; CASE CONTROL STUDY; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; DRUG OVERDOSE; EPITHELIUM CELL; GENETICS; KIDNEY PROXIMAL TUBULE; METABOLISM; MIDDLE AGED; PREDICTIVE VALUE; TIME FACTOR; URINALYSIS; URINE; YOUNG ADULT;

ACETAMINOPHEN; ACUTE KIDNEY INJURY; ADULT; BIOMARKERS; CASE-CONTROL STUDIES; CELLS, CULTURED; CISPLATIN; CROSS-SECTIONAL STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG OVERDOSE; EPITHELIAL CELLS; FEMALE; HEPATITIS A VIRUS CELLULAR RECEPTOR 1; HUMANS; KIDNEY TUBULES, PROXIMAL; LONGITUDINAL STUDIES; MALE; MICRORNAS; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; TIME FACTORS; URINALYSIS; YOUNG ADULT;

EID: 84991328204     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfw077     Document Type: Article

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