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Volumn 32, Issue 10-11, 2016, Pages 1089-1096

NKG2D Acts as a Co-Receptor for Natural Killer Cell-Mediated Anti-HIV-1 Antibody-Dependent Cellular Cytotoxicity

Author keywords

ADCC; NK cells; NKG2D

Indexed keywords

CD16 ANTIGEN; GLYCOPROTEIN GP 120; LACTATE DEHYDROGENASE; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2D; CELL SURFACE RECEPTOR; KLRK1 PROTEIN, HUMAN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K;

EID: 84991320247     PISSN: 08892229     EISSN: 19318405     Source Type: Journal    
DOI: 10.1089/aid.2016.0099     Document Type: Article
Times cited : (30)

References (44)
  • 1
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebocontrolled, test-of-concept trial
    • Buchbinder SP, Mehrotra DV, Duerr A, et al. : Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebocontrolled, test-of-concept trial. Lancet 2008;372:1881-1893.
    • (2008) Lancet , vol.372 , pp. 1881-1893
    • Buchbinder, S.P.1    Mehrotra, D.V.2    Duerr, A.3
  • 2
    • 84887865083 scopus 로고    scopus 로고
    • Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine
    • Hammer SM, Sobieszczyk ME, Janes H, et al. : Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine. N Engl J Med 2013;369:2083-2092.
    • (2013) N Engl J Med , vol.369 , pp. 2083-2092
    • Hammer, S.M.1    Sobieszczyk, M.E.2    Janes, H.3
  • 3
  • 4
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
    • Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, et al. : Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med 2009;361: 2209-2220.
    • (2009) N Engl J Med , vol.361 , pp. 2209-2220
    • Rerks-Ngarm, S.1    Pitisuttithum, P.2    Nitayaphan, S.3
  • 5
    • 84859393693 scopus 로고    scopus 로고
    • Immunecorrelates analysis of an HIV-1 vaccine efficacy trial
    • Haynes BF, Gilbert PB, McElrath MJ, et al. : Immunecorrelates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med 2012;366:1275-1286.
    • (2012) N Engl J Med , vol.366 , pp. 1275-1286
    • Haynes, B.F.1    Gilbert, P.B.2    McElrath, M.J.3
  • 6
    • 84863932778 scopus 로고    scopus 로고
    • Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials
    • Montefiori DC, Karnasuta C, Huang Y, et al. : Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials. J Infect Dis 2012;206:431-441.
    • (2012) J Infect Dis , vol.206 , pp. 431-441
    • Montefiori, D.C.1    Karnasuta, C.2    Huang, Y.3
  • 7
    • 84878430727 scopus 로고    scopus 로고
    • Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG
    • Tomaras GD, Ferrari G, Shen X, et al. : Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG. Proc Natl Acad Sci U S A 2013;110:9019-9024.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 9019-9024
    • Tomaras, G.D.1    Ferrari, G.2    Shen, X.3
  • 8
    • 84883774338 scopus 로고    scopus 로고
    • Comparative efficiency of HIV-1-infected T cell killing by NK cells, monocytes and neutrophils
    • Smalls-Mantey A, Connors M, Sattentau QJ: Comparative efficiency of HIV-1-infected T cell killing by NK cells, monocytes and neutrophils. PLoS One 2013;8:e74858.
    • (2013) PLoS One , vol.8 , pp. e74858
    • Smalls-Mantey, A.1    Connors, M.2    Sattentau, Q.J.3
  • 9
    • 11144299492 scopus 로고    scopus 로고
    • NK cell recognition
    • Lanier LL: NK cell recognition. Annu Rev Immunol 2005; 23:225-274.
    • (2005) Annu Rev Immunol , vol.23 , pp. 225-274
    • Lanier, L.L.1
  • 10
    • 84902178747 scopus 로고    scopus 로고
    • KIR/HLA interactions negatively affect rituximab-but not GA101 (obinutuzumab)-induced antibody-dependent cellular cytotoxicity
    • Terszowski G, Klein C, Stern M: KIR/HLA interactions negatively affect rituximab-but not GA101 (obinutuzumab)-induced antibody-dependent cellular cytotoxicity. J Immunol 2014;192:5618-5624.
    • (2014) J Immunol , vol.192 , pp. 5618-5624
    • Terszowski, G.1    Klein, C.2    Stern, M.3
  • 11
    • 4444276508 scopus 로고    scopus 로고
    • HLA-C and HLA-E reduce antibody-dependent natural killer cell-mediated cytotoxicity of HIV-infected primary T cell blasts
    • Ward JP, Bonaparte MI, Barker E: HLA-C and HLA-E reduce antibody-dependent natural killer cell-mediated cytotoxicity of HIV-infected primary T cell blasts. AIDS 2004;18:1769-1779.
    • (2004) AIDS , vol.18 , pp. 1769-1779
    • Ward, J.P.1    Bonaparte, M.I.2    Barker, E.3
  • 12
    • 84919458612 scopus 로고    scopus 로고
    • Slaying the Trojan horse: Natural killer cells exhibit robust anti-HIV-1 antibody-dependent activation and cytolysis against allogeneic T cells
    • Gooneratne SL, Richard J, Lee WS, Finzi A, Kent SJ, Parsons MS: Slaying the Trojan horse: Natural killer cells exhibit robust anti-HIV-1 antibody-dependent activation and cytolysis against allogeneic T cells. J Virol 2015;89:97-109.
    • (2015) J Virol , vol.89 , pp. 97-109
    • Gooneratne, S.L.1    Richard, J.2    Lee, W.S.3    Finzi, A.4    Kent, S.J.5    Parsons, M.S.6
  • 13
    • 85047699580 scopus 로고    scopus 로고
    • Clinical scale isolation of T cell-depleted CD56+ donor lymphocytes in children
    • Lang P, Pfeiffer M, Handgretinger R, et al. : Clinical scale isolation of T cell-depleted CD56+ donor lymphocytes in children. Bone Marrow Transplant 2002;29:497-502.
    • (2002) Bone Marrow Transplant , vol.29 , pp. 497-502
    • Lang, P.1    Pfeiffer, M.2    Handgretinger, R.3
  • 14
    • 84861413897 scopus 로고    scopus 로고
    • HIV infection abrogates the functional advantage of natural killer cells educated through KIR3DL1/HLA-Bw4 interactions to mediate anti-HIV antibody-dependent cellular cytotoxicity
    • Parsons MS, Wren L, Isitman G, et al. : HIV infection abrogates the functional advantage of natural killer cells educated through KIR3DL1/HLA-Bw4 interactions to mediate anti-HIV antibody-dependent cellular cytotoxicity. J Virol 2012;86:4488-4495.
    • (2012) J Virol , vol.86 , pp. 4488-4495
    • Parsons, M.S.1    Wren, L.2    Isitman, G.3
  • 15
    • 30144443832 scopus 로고    scopus 로고
    • Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
    • Bryceson YT, March ME, Ljunggren HG, Long EO: Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood 2006;107:159-166.
    • (2006) Blood , vol.107 , pp. 159-166
    • Bryceson, Y.T.1    March, M.E.2    Ljunggren, H.G.3    Long, E.O.4
  • 16
    • 48249116797 scopus 로고    scopus 로고
    • Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals
    • Fogli M, Mavilio D, Brunetta E, et al. : Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals. PLoS Pathog 2008;4:e1000101.
    • (2008) PLoS Pathog , vol.4 , pp. e1000101
    • Fogli, M.1    Mavilio, D.2    Brunetta, E.3
  • 17
    • 77949903887 scopus 로고    scopus 로고
    • HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing
    • Richard J, Sindhu S, Pham TN, Belzile JP, Cohen EA: HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing. Blood 2010;115:1354-1363.
    • (2010) Blood , vol.115 , pp. 1354-1363
    • Richard, J.1    Sindhu, S.2    Pham, T.N.3    Belzile, J.P.4    Cohen, E.A.5
  • 18
    • 34548009372 scopus 로고    scopus 로고
    • HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T-cell blasts
    • Ward J, Bonaparte M, Sacks J, et al. : HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T-cell blasts. Blood 2007;110:1207-1214.
    • (2007) Blood , vol.110 , pp. 1207-1214
    • Ward, J.1    Bonaparte, M.2    Sacks, J.3
  • 19
    • 84987786652 scopus 로고    scopus 로고
    • Higher expression of activating receptors on cytotoxic NK cells is associated with early control on HIV-1C multiplication
    • Kulkarni AG, Paranjape RS, Thakar MR: higher expression of activating receptors on cytotoxic NK cells is associated with early control on HIV-1C multiplication. Front Immunol 2014;5:222.
    • (2014) Front Immunol , vol.5 , pp. 222
    • Kulkarni, A.G.1    Paranjape, R.S.2    Thakar, M.R.3
  • 20
    • 33846141778 scopus 로고    scopus 로고
    • Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity
    • Cerboni C, Neri F, Casartelli N, et al. : Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity. J Gen Virol 2007;88(Pt 1):242-250.
    • (2007) J Gen Virol , vol.88 , pp. 242-250
    • Cerboni, C.1    Neri, F.2    Casartelli, N.3
  • 21
    • 78349264184 scopus 로고    scopus 로고
    • Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu
    • Shah AH, Sowrirajan B, Davis ZB, et al. : Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu. Cell Host Microbe 2010;8:397-409.
    • (2010) Cell Host Microbe , vol.8 , pp. 397-409
    • Shah, A.H.1    Sowrirajan, B.2    Davis, Z.B.3
  • 22
    • 77956174618 scopus 로고    scopus 로고
    • MHC class i chainrelated protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction
    • Nolting A, Dugast AS, Rihn S, et al. : MHC class I chainrelated protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction. Virology 2010;406:12-20.
    • (2010) Virology , vol.406 , pp. 12-20
    • Nolting, A.1    Dugast, A.S.2    Rihn, S.3
  • 23
    • 84878763877 scopus 로고    scopus 로고
    • Soluble ligands for the NKG2D receptor are released during HIV-1 infection and impair NKG2D expression and cytotoxicity of NK cells
    • Matusali G, Tchidjou HK, Pontrelli G, et al. : Soluble ligands for the NKG2D receptor are released during HIV-1 infection and impair NKG2D expression and cytotoxicity of NK cells. FASEB J 2013;27:2440-2450.
    • (2013) FASEB J , vol.27 , pp. 2440-2450
    • Matusali, G.1    Tchidjou, H.K.2    Pontrelli, G.3
  • 24
    • 79251577713 scopus 로고    scopus 로고
    • A human NK cell activation/inhibition threshold allows small changes in the target cell surface phenotype to dramatically alter susceptibility to NK cells
    • Holmes TD, El-Sherbiny YM, Davison A, Clough SL, Blair GE, Cook GP: A human NK cell activation/inhibition threshold allows small changes in the target cell surface phenotype to dramatically alter susceptibility to NK cells. J Immunol 2011;186:1538-1545.
    • (2011) J Immunol , vol.186 , pp. 1538-1545
    • Holmes, T.D.1    El-Sherbiny, Y.M.2    Davison, A.3    Clough, S.L.4    Blair, G.E.5    Cook, G.P.6
  • 25
    • 84906484922 scopus 로고    scopus 로고
    • Flow cytometry-based assay to study HIV-1 gp120 specific antibody-dependent cellular cytotoxicity responses
    • Richard J, Veillette M, Batraville LA, et al. : Flow cytometry-based assay to study HIV-1 gp120 specific antibody-dependent cellular cytotoxicity responses. J Virol Methods 2014;208:107-114.
    • (2014) J Virol Methods , vol.208 , pp. 107-114
    • Richard, J.1    Veillette, M.2    Batraville, L.A.3
  • 26
    • 84896702279 scopus 로고    scopus 로고
    • Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity
    • Veillette M, Desormeaux A, Medjahed H, et al. : Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity. J Virol 2014;88:2633-2644.
    • (2014) J Virol , vol.88 , pp. 2633-2644
    • Veillette, M.1    Desormeaux, A.2    Medjahed, H.3
  • 27
    • 84919429656 scopus 로고    scopus 로고
    • The HIV-1 gp120 CD4-bound conformation is preferentially targeted by antibody-dependent cellular cytotoxicity-mediating antibodies in sera from HIV-1-infected individuals
    • Veillette M, Coutu M, Richard J, et al. : The HIV-1 gp120 CD4-bound conformation is preferentially targeted by antibody-dependent cellular cytotoxicity-mediating antibodies in sera from HIV-1-infected individuals. J Virol 2015; 89:545-551.
    • (2015) J Virol , vol.89 , pp. 545-551
    • Veillette, M.1    Coutu, M.2    Richard, J.3
  • 28
    • 84907991957 scopus 로고    scopus 로고
    • Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection
    • Acharya P, Tolbert WD, Gohain N, et al. : Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection. J Virol 2014;88:12895-12906.
    • (2014) J Virol , vol.88 , pp. 12895-12906
    • Acharya, P.1    Tolbert, W.D.2    Gohain, N.3
  • 29
    • 79960342938 scopus 로고    scopus 로고
    • An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibodydependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum
    • Ferrari G, Pollara J, Kozink D, et al. : An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibodydependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum. J Virol 2011;85:7029-7036.
    • (2011) J Virol , vol.85 , pp. 7029-7036
    • Ferrari, G.1    Pollara, J.2    Kozink, D.3
  • 30
    • 84929590788 scopus 로고    scopus 로고
    • CD4 mimetics sensitize HIV-1-infected cells to ADCC
    • Richard J, Veillette M, Brassard N, et al. : CD4 mimetics sensitize HIV-1-infected cells to ADCC. Proc Natl Acad Sci U S A 2015;112:E2687-E2694.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. E2687-E2694
    • Richard, J.1    Veillette, M.2    Brassard, N.3
  • 31
    • 73349122322 scopus 로고    scopus 로고
    • HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response
    • Ward J, Davis Z, DeHart J, et al. : HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response. PLoS Pathog 2009;5:e1000613.
    • (2009) PLoS Pathog , vol.5 , pp. e1000613
    • Ward, J.1    Davis, Z.2    DeHart, J.3
  • 32
    • 84857489390 scopus 로고    scopus 로고
    • Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A
    • Nielsen N, Odum N, Urso B, Lanier LL, Spee P: Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A. PLoS One 2012;7:e31959.
    • (2012) PLoS One , vol.7 , pp. e31959
    • Nielsen, N.1    Odum, N.2    Urso, B.3    Lanier, L.L.4    Spee, P.5
  • 33
    • 84864243685 scopus 로고    scopus 로고
    • HIV: Shock and kill
    • Deeks SG: HIV: Shock and kill. Nature 2012;487:439-440.
    • (2012) Nature , vol.487 , pp. 439-440
    • Deeks, S.G.1
  • 34
    • 84958056913 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity against reactivated HIV-1-infected cells
    • Lee WS, Richard J, Lichtfuss M, et al. : Antibody-dependent cellular cytotoxicity against reactivated HIV-1-infected cells. J Virol 2015;90:2021-2030.
    • (2015) J Virol , vol.90 , pp. 2021-2030
    • Lee, W.S.1    Richard, J.2    Lichtfuss, M.3
  • 35
    • 33846467149 scopus 로고    scopus 로고
    • CD56(dim)CD16(+) NK cells downregulate CD16 following target cell induced activation of matrix metalloproteinases
    • author reply 359
    • Grzywacz B, Kataria N, Verneris MR: CD56(dim)CD16(+) NK cells downregulate CD16 following target cell induced activation of matrix metalloproteinases. Leukemia 2007;21: 356-359, author reply 359.
    • (2007) Leukemia , vol.21 , pp. 356-359
    • Grzywacz, B.1    Kataria, N.2    Verneris, M.R.3
  • 36
    • 84891121586 scopus 로고    scopus 로고
    • Anti-HIV antibody-dependent activation of NK cells impairs NKp46 expression
    • Parsons MS, Tang CC, Jegaskanda S, et al. : Anti-HIV antibody-dependent activation of NK cells impairs NKp46 expression. J Immunol 2014;192:308-315.
    • (2014) J Immunol , vol.192 , pp. 308-315
    • Parsons, M.S.1    Tang, C.C.2    Jegaskanda, S.3
  • 37
    • 84879703012 scopus 로고    scopus 로고
    • NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)
    • Romee R, Foley B, Lenvik T, et al. : NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17). Blood 2013;121:3599-3608.
    • (2013) Blood , vol.121 , pp. 3599-3608
    • Romee, R.1    Foley, B.2    Lenvik, T.3
  • 38
    • 84948095470 scopus 로고    scopus 로고
    • Phenotypic and functional profiles of NK cells exhibiting MMP-mediated CD16 cleavage after anti-HIV antibody-dependent activation
    • Tang CC, Isitman G, Bruneau J, et al. : Phenotypic and functional profiles of NK cells exhibiting MMP-mediated CD16 cleavage after anti-HIV antibody-dependent activation. Clin Exp Immunol 2015;181:275-285.
    • (2015) Clin Exp Immunol , vol.181 , pp. 275-285
    • Tang, C.C.1    Isitman, G.2    Bruneau, J.3
  • 39
    • 84878784248 scopus 로고    scopus 로고
    • Matrix metalloproteinases inhibition promotes the polyfunctionality of human natural killer cells in therapeutic antibody-based anti-tumour immunotherapy
    • Zhou Q, Gil-Krzewska A, Peruzzi G, Borrego F: Matrix metalloproteinases inhibition promotes the polyfunctionality of human natural killer cells in therapeutic antibody-based anti-tumour immunotherapy. Clin Exp Immunol 2013;173: 131-139.
    • (2013) Clin Exp Immunol , vol.173 , pp. 131-139
    • Zhou, Q.1    Gil-Krzewska, A.2    Peruzzi, G.3    Borrego, F.4
  • 40
    • 20044391050 scopus 로고    scopus 로고
    • Characterization of CD56-/CD16+ natural killer (NK) cells: A highly dysfunctional NK subset expanded in HIV-infected viremic individuals
    • Mavilio D, Lombardo G, Benjamin J, et al. : Characterization of CD56-/CD16+ natural killer (NK) cells: A highly dysfunctional NK subset expanded in HIV-infected viremic individuals. Proc Natl Acad Sci U S A 2005;102:2886-2891.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2886-2891
    • Mavilio, D.1    Lombardo, G.2    Benjamin, J.3
  • 41
    • 84975282877 scopus 로고    scopus 로고
    • NKG2C(+)CD57(+) natural killer cell expansion parallels cytomegalovirus-specific CD8(+) T cell evolution towards senescence
    • Heath J, Newhook N, Comeau E, Gallant M, Fudge N, Grant M: NKG2C(+)CD57(+) natural killer cell expansion parallels cytomegalovirus-specific CD8(+) T cell evolution towards senescence. J Immunol Res 2016;2016:7470124.
    • (2016) J Immunol Res , vol.2016 , pp. 7470124
    • Heath, J.1    Newhook, N.2    Comeau, E.3    Gallant, M.4    Fudge, N.5    Grant, M.6
  • 42
    • 84880382483 scopus 로고    scopus 로고
    • Human cytomegalovirusinduced NKG2C(hi) CD57(hi) natural killer cells are effectors dependent on humoral antiviral immunity
    • Wu Z, Sinzger C, Frascaroli G, et al. : Human cytomegalovirusinduced NKG2C(hi) CD57(hi) natural killer cells are effectors dependent on humoral antiviral immunity. J Virol 2013;87:7717-7725.
    • (2013) J Virol , vol.87 , pp. 7717-7725
    • Wu, Z.1    Sinzger, C.2    Frascaroli, G.3
  • 43
    • 84886778759 scopus 로고    scopus 로고
    • Obstacles to ideal anti-HIV antibody-dependent cellular cytotoxicity responses
    • Wren LH, Stratov I, Kent SJ, Parsons MS: Obstacles to ideal anti-HIV antibody-dependent cellular cytotoxicity responses. Vaccine 2013;31:5506-5517.
    • (2013) Vaccine , vol.31 , pp. 5506-5517
    • Wren, L.H.1    Stratov, I.2    Kent, S.J.3    Parsons, M.S.4
  • 44
    • 84879778221 scopus 로고    scopus 로고
    • The search for an HIV cure: Tackling latent infection
    • Kent SJ, Reece JC, Petravic J, et al. : The search for an HIV cure: Tackling latent infection. Lancet Infect Dis 2013;13: 614-621.
    • (2013) Lancet Infect Dis , vol.13 , pp. 614-621
    • Kent, S.J.1    Reece, J.C.2    Petravic, J.3


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