NKG2C+CD57+ Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8+ T Cell Evolution towards Senescence

Journal of Immunology Research

Volumn 2016, Issue , 2016, Pages

  Heath, John ^a   Newhook, Nicholas ^a   Comeau, Emilie ^a   Gallant, Maureen ^a   Fudge, Neva ^a   Grant, Michael ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD57 ANTIGEN; CYTOMEGALOVIRUS ANTIBODY; GAMMA INTERFERON; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2C; UNCLASSIFIED DRUG; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY C; VIRUS ANTIBODY;

ADAPTIVE IMMUNITY; ADULT; ANTIBODY RESPONSE; ARTICLE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL LYSATE; CELL STIMULATION; CLINICAL ASSESSMENT; CLINICAL EVALUATION; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CYTOMEGALOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MOLECULAR EVOLUTION; NATURAL KILLER CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; POPULATION; SENESCENCE; CELL AGING; CYTOMEGALOVIRUS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE SUBPOPULATION; METABOLISM; PHENOTYPE;

ANTIBODIES, VIRAL; ANTIGENS, CD57; CD8-POSITIVE T-LYMPHOCYTES; CELL AGING; COINFECTION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; HIV INFECTIONS; HUMANS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE SUBSETS; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY C; PHENOTYPE;

EID: 84975282877     PISSN: 23148861     EISSN: 23147156     Source Type: Journal    
DOI: 10.1155/2016/7470124     Document Type: Article

References (40)

1. N. Anfossi, P. André, S. Guia et al., "Human NK cell education by inhibitory receptors for MHC class I, " Immunity, vol. 25, no. 2, pp. 331-342, 2006.
2. S. Kim, J. Poursine-Laurent, S. M. Truscott et al., "Licensing of natural killer cells by host major histocompatibility complex class I molecules, " Nature, vol. 436, no. 7051, pp. 709-713, 2005.
3. S. Kim, J. B. Sunwoo, L. Yang et al., "HLA alleles determine differences in human natural killer cell responsiveness and potency, " Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 8, pp. 3053-3058, 2008.
4. H. Arase, E. S. Mocarski, A. E. Campbell, A. B. Hill, and L. L. Lanier, "Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors, " Science, vol. 296, no. 5571, pp. 1323-1326, 2002.
5. H. R. C. Smith, J. W. Heusel, I. K. Mehta et al., "Recognition of a virus-encoded ligand by a natural killer cell activation receptor, " Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 13, pp. 8826-8831, 2002.
6. A. O. Dokun, S. Kim, H. R. C. Smith, H.-S. P. Kang, D. T. Chu, and W. M. Yokoyama, "Specific and nonspecific NK cell activation during virus infection, " Nature Immunology, vol. 2, no. 10, pp. 951-956, 2001.
7. M. G. Brown, A. O. Dokun, J. W. Heusel et al., "Vital involvement of a natural killer cell activation receptor in resistance to viral infection, " Science, vol. 292, no. 5518, pp. 934-937, 2001.
8. K. A. Daniels, G. Devora, W. C. Lai, C. L. O'Donnell, M. Bennett, and R. M. Welsh, "Murine cytomegalovirus is regulated by a discrete subset of natural killer cells reactive with monoclonal antibody to Ly49H, "The Journal of Experimental Medicine, vol. 194, no. 1, pp. 29-44, 2001.
9. J. C. Sun, J. N. Beilke, and L. L. Lanier, "Adaptive immune features of natural killer cells, " Nature, vol. 457, pp. 557-561, 2009.
10. S. Paust and U. H. von Andrian, "Natural killer cell memory, " Nature Immunology, vol. 12, no. 6, pp. 500-508, 2011.
11. S. Rajagopalan and E. O. Long, "Understanding how combinations of HLA and KIR genes influence disease, " The Journal of Experimental Medicine, vol. 201, no. 7, pp. 1025-1029, 2005.
12. L. L. Lanier, "Evolutionary struggles between NK cells and viruses, " Nature Reviews Immunology, vol. 8, no. 4, pp. 259-268, 2008.
13. G. Alter, M. P. Martin, N. Teigen et al., "Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes, "The Journal of ExperimentalMedicine, vol. 204, no. 12, pp. 3027-3036, 2007.
14. G. Alter, S. Rihn, K. Walter et al., "HLA class I subtypedependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection, " Journal of Virology, vol. 83, no. 13, pp. 6798-6805, 2009.
15. G. Alter, D. Heckerman, A. Schneidewind et al., "HIV-1 adaptation to NK-cell-mediated immune pressure, " Nature, vol. 476, no. 7358, pp. 96-101, 2011.
16. L. Tong, M. Assenmacher, K. S. Zänker, and P. Jähn, "Virusspecific peptide dependent NK cell cytotoxicity, " Inflammation and Allergy-Drug Targets, vol. 13, no. 2, pp. 128-133, 2014.
17. R. K. Reeves, H. Li, S. Jost et al., "Antigen-specific NK cell memory in rhesus macaques, " Nature Immunology, vol. 16, no. 9, pp. 927-932, 2015.
18. M. Gumá, A. Angulo, C. Vilches, N. Gómez-Lozano, N. Malats, and M. López-Botet, "Imprint of human cytomegalovirus infection on the NK cell receptor repertoire, " Blood, vol. 104, no. 12, pp. 3664-3671, 2004.
19. C. M. Mela, C. T. Burton, N. Imami et al., "Switch from inhibitory to activating NKG2 receptor expression in HIV-1 infection: lack of reversion with highly active antiretroviral therapy, " AIDS, vol. 19, no. 16, pp. 1761-1769, 2005.
20. S. Lopez-Vergès, J. M. Milush, B. S. Schwartz et al., "Expansion of a unique CD57+NKG2C hi natural killer cell subset during acute human cytomegalovirus infection, " Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 36, pp. 14725-14732, 2011.
21. V. Béziat, O. Dalgard, T. Asselah et al., "CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients, " European Journal of Immunology, vol. 42, no. 2, pp. 447-457, 2012.
22. Z. Wu, C. Sinzger, G. Frascaroli et al., "Human cytomegalovirusinduced NKG2C(hi) CD57(hi) natural killer cells are effectors dependent on humoral antiviral immunity, " Journal of Virology, vol. 87, no. 13, pp. 7717-7725, 2013.
23. I. Hwang, T. Zhang, J. M. Scott et al., "Identification of human NK cells that are deficient for signaling adaptor FcR and specialized for antibody-dependent immune functions, " International Immunology, vol. 24, no. 12, pp. 793-802, 2012.
24. T. Zhang, J. M. Scott, I. Hwang, and S. Kim, "Cutting edge: antibody-dependent memory-like NK cells distinguished by FcR deficiency, " The Journal of Immunology, vol. 190, no. 4, pp. 1402-1406, 2013.
25. J. Lee, T. Zhang, I. Hwang et al., "Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals, " Immunity, vol. 42, no. 3, pp. 431-442, 2015.
26. H. Schlums, F. Cichocki, B. Tesi et al., "Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function, " Immunity, vol. 42, no. 3, pp. 443-456, 2015.
27. D. M. Naeger, J. N. Martin, E. Sinclair et al., "Cytomegalovirusspecific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease, " PLoS ONE, vol. 5, no. 1, article e8886, 2010.
28. C. M. Parrinello, E. Sinclair, A. L. Landay et al., "Cytomegalovirus immunoglobulin G antibody is associated with subclinical carotid artery disease among HIV-infected women, " Journal of Infectious Diseases, vol. 205, no. 12, pp. 1788-1796, 2012.
29. R. Miyashita, N. Tsuchiya, K. Hikami et al., "Molecular genetic analyses of human NKG2C (KLRC2) gene deletion, " International Immunology, vol. 16, no. 1, pp. 163-168, 2004.
30. W. P. Rowe, R. J. Huebner, L. K. Gilmore, R. H. Parrott, and T. G. Ward, "Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture, " Proceedings of the Society for Experimental Biology and Medicine, vol. 84, no. 3, pp. 570-573, 1953.
31. R. B. Effros, "Replicative senescence of CD8 T cells: effect on human ageing, " Experimental Gerontology, vol. 39, no. 4, pp. 517-524, 2004.
32. R. B. Effros, "Replicative senescence of CD8 T cells: potential effects on cancer immune surveillance and immunotherapy, " Cancer Immunology, Immunotherapy, vol. 53, no. 10, pp. 925-933, 2004.
33. B. Foley, S. Cooley, M. R. Verneris et al., "Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function, " Blood, vol. 119, no. 11, pp. 2665-2674, 2012.
34. S. Gianella, C. M. Anderson, M. V. Vargas et al., "Cytomegalovirus DNA in semen and blood is associated with higher levels of proviral HIV DNA, " Journal of Infectious Diseases, vol. 207, no. 6, pp. 898-902, 2013.
35. S. Gianella, S. R. Morris, E. Tatro et al., "Virologic correlates of anti-CMV IgG levels in HIV-1-infected men, " The Journal of Infectious Diseases, vol. 209, no. 3, pp. 452-456, 2014.
36. S. Gianella, S. R. Morris, M. V. Vargas et al., "Role of seminal shedding of herpesviruses in HIV type 1 transmission, " Journal of Infectious Diseases, vol. 207, no. 2, pp. 257-261, 2013.
37. M. Bengnér, V. Béziat, J. Ernerudh et al., "Independent skewing of the T cell and NK cell compartments associated with cytomegalovirus infection suggests division of labor between innate and adaptive immunity, " Age, vol. 36, no. 2, pp. 571-582, 2014.
38. A. B. Bigley, G. Spielmann, N. Agha, D. P. O'Connor, and R. J. Simpson, "Dichotomous effects of latent CMV infection on the phenotype and functional properties of CD8+ T-cells and NKcells, " Cellular Immunology, vol. 300, pp. 26-32, 2016.
39. R. B. Effros, N. Boucher, V. Porter et al., "Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence, " Experimental Gerontology, vol. 29, no. 6, pp. 601-609, 1994.
40. R. B. Effros, "FromHayflick toWalford: the role of T cell replicative senescence in human aging, " ExperimentalGerontology, vol. 39, no. 6, pp. 885-890, 2004.