Studying closed hydrodynamic models of "in vivo" DNA perfusion in pig liver for gene therapy translation to humans

PLoS ONE

Volumn 11, Issue 10, 2016, Pages

  Sendra, Luis ^a   Miguel, Antonio ^a   Pérez Enguix, Daniel ^b   Herrero, María José ^a,c   Montalvá, Eva ^b   García Gimeno, María Adelaida ^d   Noguera, Inmaculada ^e   Díaz, Ana ^e   Pérez, Judith ^b   Sanz, Pascual ^d   López Andújar, Rafael ^b   Martí Bonmatí, Luis ^b   Aliño, Salvador F ^a,b,c  

^a UNIVERSITY OF VALENCIA   (Spain)

^b HOSPITAL UNIVERSITARIO LA FE   (Spain)

^c INSTITUTO DE INVESTIGACIÓN SANITARIA DEL HOSPITAL CLÍNICO SAN CARLOS IDISSC   (Spain)

^d CSIC   (Spain)

^e UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; DNA; GOLD; METAL NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATHETERIZATION; CONTROLLED STUDY; ENDOVASCULAR SURGERY; FEMALE; GENE EXPRESSION; GENE THERAPY; HUMAN; HUMAN TISSUE; HYDRODYNAMICS BASED TRANSFECTION; IN VIVO GENE TRANSFER; INFERIOR CAVA VEIN; LIVER CIRCULATION; LIVER PERFUSION; MALE; MOUSE; NONHUMAN; PIG; PROTEIN BLOOD LEVEL; TISSUE LEVEL; ADMINISTRATION AND DOSAGE; ANIMAL; ANTIBODY SPECIFICITY; BLOOD; GENE TRANSFER; GENETICS; HYDRODYNAMICS; LIVER; METABOLISM; PERFUSION; PLASMID; PROCEDURES; TRANSGENE; TRANSLATIONAL RESEARCH;

ALPHA 1-ANTITRYPSIN; ANIMALS; CATHETERIZATION; DNA; FEMALE; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GOLD; HUMANS; HYDRODYNAMICS; LIVER; MALE; METAL NANOPARTICLES; MICE; ORGAN SPECIFICITY; PERFUSION; PLASMIDS; SWINE; TRANSGENES; TRANSLATIONAL MEDICAL RESEARCH;

EID: 84991270763     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0163898     Document Type: Article

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