Antibiotics as a selective driver for conjugation dynamics

Nature Microbiology

Volumn 1, Issue 6, 2016, Pages

  Lopatkin, Allison J ^a   Huang, Shuqiang ^a   Smith, Robert P ^c   Srimani, Jaydeep K ^a   Sysoeva, Tatyana A ^a   Bewick, Sharon ^d   Karig, David K ^e   You, Lingchong ^a,b  

^a Duke University   (United States)

^b DUKE UNIVERSITY   (United States)

^c NOVA SOUTHEASTERN UNIVERSITY   (United States)

^d Bldg 142   (United States)

^e JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; BACTERIUM CONJUGATION; BIOLOGICAL MODEL; DRUG EFFECTS; ESCHERICHIA COLI; GENETIC SELECTION; GENETICS; HUMAN; MICROBIAL SENSITIVITY TEST; MICROFLUIDIC ANALYSIS; MOLECULAR DYNAMICS; PLASMID;

ANTI-BACTERIAL AGENTS; CONJUGATION, GENETIC; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; HUMANS; MICROBIAL SENSITIVITY TESTS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MODELS, BIOLOGICAL; MOLECULAR DYNAMICS SIMULATION; PLASMIDS; SELECTION, GENETIC;

EID: 84991258123     PISSN: None     EISSN: 20585276     Source Type: Journal    
DOI: 10.1038/nmicrobiol.2016.44     Document Type: Article

References (50)

1. Maiden, M. C. J. Horizontal genetic exchange, evolution, and spread of antibiotic resistance in bacteria. Clin. Infect. Dis. 27, S12-S20 (1998).
2. Mazel, D. & Davies, J. Antibiotic resistance in microbes. Cell. Mol. Life Sci. 56, 742-754 (1999).
3. Barlow, M. What antimicrobial resistance has taught us about horizontal gene transfer. Methods Mol. Biol. 532, 397-411 (2009).
4. Andersson, D. I. & Hughes, D. Microbiological effects of sublethal levels of antibiotics. Nature Rev. Microbiol. 12, 465-478 (2014).
5. Aminov, R. I. Horizontal gene exchange in environmental microbiota. Front. Microbiol. 2, 158 (2011).
6. Norman, A., Hansen, L. H. & Sørensen, S. J. Conjugative plasmids: vessels of the communal gene pool. Phil. Trans. R. Soc. B Biol. Sci. 364, 2275-2289 (2009).
7. Davison, J. Genetic exchange between bacteria in the environment. Plasmid 42, 73-91 (1999).
8. Stevens, A. M., Shoemaker, N. B., Li, L. Y. & Salyers, A. A. Tetracycline regulation of genes on Bacteroides conjugative transposons. J. Bacteriol. 175, 6134-6141 (1993).
9. Shoemaker, N. B. & Salyers, A. A. Tetracycline-dependent appearance of plasmidlike forms in Bacteroides uniformis 0061 mediated by conjugal Bacteroides tetracycline resistance elements. J. Bacteriol. 170, 1651-1657 (1988).
10. Salyers, A. A., Shoemaker, N. B. & Li, L. Y. In the driver's seat: the Bacteroides conjugative transposons and the elements they mobilize. J. Bacteriol. 177, 5727-5731 (1995).
11. Whittle, G., Shoemaker, N. B. & Salyers, A. A. Characterization of genes involved in modulation of conjugal transfer of the Bacteroides conjugative transposon CTnDOT. J. Bacteriol. 184, 3839-3847 (2002).
12. Beaber, J. W., Hochhut, B. & Waldor, M. K. SOS response promotes horizontal dissemination of antibiotic resistance genes. Nature 427, 72-74 (2003).
13. Al-Masaudi, S. B., Day, M. J. & Russell, A. D. Effect of some antibiotics and biocides on plasmid transfer in Staphylococcus aureus. J. Appl. Bacteriol. 71, 239-243 (1991).
14. Zhang, P.-Y. et al. Combined treatment with the antibiotics kanamycin and streptomycin promotes the conjugation of Escherichia coli. FEMS Microbiol. Lett. 348, 149-156 (2013).
15. Xia, Z.-J. et al. Improving conjugation efficacy of Sorangium cellulosum by the addition of dual selection antibiotics. J. Ind. Microbiol. Biotechnol. 35, 1157-1163 (2008).
16. Schuurmans, J. M. et al. Effect of growth rate and selection pressure on rates of transfer of an antibiotic resistance plasmid between E. coli strains. Plasmid 72, 1-8 (2014).
17. Ma, H. & Bryers, J. D. Non-invasive determination of conjugative transfer of plasmids bearing antibiotic-resistance genes in biofilm-bound bacteria: effects of substrate loading and antibiotic selection. Appl. Microbiol. Biotechnol. 97, 317-328 (2013).
18. Rensing, C., Newby, D. T. & Pepper, I. L. The role of selective pressure and selfish DNA in horizontal gene transfer and soil microbial community adaptation. Soil Biol. Biochem. 34, 285-296 (2002).
19. Johnsen, A. R. & Kroer, N. Effects of stress and other environmental factors on horizontal plasmid transfer assessed by direct quantification of discrete transfer events: effects of environmental factors on horizontal plasmid transfer. FEMS Microbiol. Ecol. 59, 718-728 (2007).
20. Sørensen, S. J., Bailey, M., Hansen, L.H., Kroer, N. & Wuertz, S. Studying plasmid horizontal transfer in situ: a critical review. Nature Rev. Microbiol. 3, 700-710 (2005).
21. Blázquez, J., Couce, A., Rodríguez-Beltrán, J. & Rodríguez-Rojas, A. Antimicrobials as promoters of genetic variation. Curr. Opin. Microbiol. 15, 561-569 (2012).
22. Smet, A. et al. In situ ESBL conjugation from avian to human Escherichia coli during cefotaxime administration. J. Appl. Microbiol. 110, 541-549 (2011).
23. Barr, V., Barr, K., Millar, M. R. & Lacey, R. W. β-Lactam antibiotics increase the frequency of plasmid transfer in Staphylococcus aureus. J. Antimicrob. Chemother. 17, 409-413 (1986).
24. Goren, M. G. et al. Transfer of carbapenem-resistant plasmid from Klebsiella pneumoniae ST258 to Escherichia coli in patient. Emerg. Infect. Dis. 16, 1014-1017 (2010).
25. Karami, N. et al. Transfer of an ampicillin resistance gene between two Escherichia coli strains in the bowel microbiota of an infant treated with antibiotics. J. Antimicrob. Chemother. 60, 1142-1145 (2007).
26. Cavaco, L. M., Abatih, E., Aarestrup, F. M. & Guardabassi, L. Selection and persistence of CTX-M-producing Escherichia coli in the intestinal flora of pigs treated with amoxicillin, ceftiofur, or cefquinome. Antimicrob. Agents Chemother. 52, 3612-3616 (2008).
27. Dimitriu, T. et al. Genetic information transfer promotes cooperation in bacteria. Proc. Natl Acad. Sci. USA 111, 11103-11108 (2014).
28. Zatyka, M. & Thomas, C. M. Control of genes for conjugative transfer of plasmids and other mobile elements. FEMS Microbiol. Rev. 21, 291-319 (1998).
29. Cheah, K. C. & Skurray, R. The F plasmid carries an IS3 insertion within finO. J. Gen. Microbiol. 132, 3269-3275 (1986).
30. Zaslaver, A. et al. A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Nature Methods 3, 623-628 (2006).
31. Luo, M. L., Mullis, A. S., Leenay, R. T. & Beisel, C. L. Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression. Nucleic Acids Res. 43, 674-681 (2015).
32. Lutz, R. & Bujard, H. Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements. Nucleic Acids Res. 25, 1203-1210 (1997).
33. Song, H., Payne, S., Gray, M. & You, L. Spatiotemporal modulation of biodiversity in a synthetic chemical-mediated ecosystem. Nature Chem. Biol. 5, 929-935 (2009).
34. Levin, B. R., Stewart, F. M. & Rice, V. A. The kinetics of conjugative plasmid transmission: fit of a simple mass action model. Plasmid 2, 247-260 (1979).
35. - phenocopies: characterization of expression of the F transfer region in stationary phase. Microbiology 144, 2579-2587 (1998).
36. Curtiss, R., Charamella, L. J., Stallions, D. R. & Mays, J. A. Parental functions during conjugation in Escherichia coli K-12. Bacteriol. Rev. 32, 320-348 (1968).
37. Hoekstra, W. P. M. & Havekes, A. M. On the role of the recipient cell during conjugation in Escherichia coli. Antonie Van Leeuwenhoek 45, 13-18 (1979).
38. Wang, Y. A., Yu, X., Silverman, P. M., Harris, R. L. & Egelman, E. H. The structure of F-pili. J. Mol. Biol. 385, 22-29 (2009).
39. Anthony, K. G., Sherburne, C., Sherburne, R. & Frost, L. S. The role of the pilus in recipient cell recognition during bacterial conjugation mediated by F-like plasmids. Mol. Microbiol. 13, 939-953 (1994).
40. Curtiss, R. & Stallions, D. R. Energy requirements for specific pair formation during conjugation in Escherichia coli K-12. J. Bacteriol. 94, 490-492 (1967).
41. Clarke, M., Maddera, L., Harris, R. L. & Silverman, P. M. F-pili dynamics by livecell imaging. Proc. Natl Acad. Sci. USA 105, 17978-17981 (2008).
42. Händel, N., Otte, S., Jonker, M., Brul, S. & ter Kuile, B. H. Factors that affect transfer of the IncI1 β-lactam resistance plasmid pESBL-283 between E. coli strains. PLoS ONE 10, e0123039 (2015).
43. Rawat, D. & Nair, D. Extended-spectrum β-lactamases in Gram negative bacteria. J. Glob. Infect. Dis. 2, 263-274 (2010).
44. Villalta, J. I. et al. New algorithm to determine true colocalization in combination with image restoration and time-lapse confocal microscopy to map kinases in mitochondria. PLoS ONE 6, e19031 (2011).
45. Stecher, B. et al. Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae. Proc. Natl Acad. Sci. USA 109, 1269-1274 (2012).
46. Barkay, T. & Smets, B. F. Horizontal gene transfer: perspectives at a crossroads of scientific disciplines. Nature Rev. Microbiol. 3, 675-678 (2005).
47. Thomas, C. M. & Nielsen, K. M. Mechanisms of, and barriers to, horizontal gene transfer between bacteria. Nature Rev. Microbiol. 3, 711-721 (2005).
48. Korem, T. et al. Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples. Science 349, 1101-1106 (2015).
49. Cormack, B. P., Valdivia, R. H. & Falkow, S. FACS-optimized mutants of the green fluorescent protein (GFP). Gene 173, 33-38 (1996).
50. Duffy, D. C., McDonald, J. C., Schueller, O. J. A. & Whitesides, G. M. Rapid prototyping of microfluidic systems in poly(dimethylsiloxane). Anal. Chem. 70, 4974-4984 (1998).