Selection and persistence of CTX-M-producing Escherichia coli in the intestinal flora of pigs treated with amoxicillin, ceftiofur, or cefquinome

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 10, 2008, Pages 3612-3616

  Cavaco, L M ^a,b   Abatih, E ^a   Aarestrup, F M ^b   Guardabassi, L ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; CEFOTAXIME; CEFQUINOME; CEFTIOFUR; CEPHALOSPORIN; EXTENDED SPECTRUM BETA LACTAMASE; NALIDIXIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL INFECTION; BIOSYNTHESIS; COLONY FORMING UNIT; CONTROLLED STUDY; ESCHERICHIA COLI; FECES ANALYSIS; FEMALE; INTESTINE FLORA; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; SWINE; TREATMENT OUTCOME; VETERINARY MEDICINE;

AMOXICILLIN; ANIMALS; ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CEPHALOSPORINS; COLONY COUNT, MICROBIAL; ESCHERICHIA COLI; FEMALE; GENES, BACTERIAL; INTESTINES; MUTATION; NALIDIXIC ACID; RESPIRATORY TRACT INFECTIONS; SUS SCROFA; SWINE DISEASES;

EID: 54049138434     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00354-08     Document Type: Article

References (21)

1. CTX-M-1- carrying Escherichia coli isolates in Danish primary food production. J. Antimicrob. Chemother. 57:1258-1259.
2. Brinas, L., M. A. Moreno, M. Zarazaga, C. Porrero, Y. Saenz, M. Garcia, L. Dominguez, and C. Torres. 2003. Detection of CMY-2, CTX-M-14, and SHV-12 beta-lactamases in Escherichia coli fecal-sample isolates from healthy chickens. Antimicrob. Agents Chemother. 47:2056-2058.
3. Burch, D., C. Duran, and F. M. Aarestrup. 2008. Guidelines for antimicrobial use in swine p. 102-125. In L. Guardabassi, L. Jensen, and H. Kruse (ed.), Guide to antimicrobial use in animals. Blackwell Publishing, Oxford, United Kingdom.
4. Canton, R., and T. M. Coque. 2006. The CTX-M beta-lactamase pandemic. Curr. Opin. Microbiol. 9:466-475.
5. Centers for Disease Control and Prevention. 2004. One-day (24-28 h) standardized laboratory protocol for molecular subtyping of Escherichia coli O157:H7, non-typhoidal Salmonella serotypes, and Shigella sonnei by pulsed field gel electrophoresis (PFGE). PulseNet manual. Centers for Disease Control and Prevention, Atlanta, GA.
6. Clermont, O., S. Bonacorsi, and E. Bingen. 2000. Rapid and simple determination of the Escherichia coli phylogenetic group. Appl. Environ. Microbiol. 66:4555-4558.
7. Delsol, A. A., M. Anjum, M. J. Woodward, J. Sunderland, and J. M. Roe. 2003. The effect of chlortetracycline treatment and its subsequent withdrawal on multi-resistant Salmonella enterica serovar Typhimurium DT104 and commensal Escherichia coli in the pig. J. Appl. Microbiol. 95:1226-1234.
8. Delsol, A. A., M. J. Woodward, and J. M. Roe. 2004. Effect of a 5 day enrofloxacin treatment on Salmonella enterica serotype Typhimurium DT104 in the pig. J. Antimicrob. Chemother. 53:396-398.
9. Duval-Iflah, Y., J. Chappuis, R. Ducluzeau, and P. Raibaud. 1983. Intraspecific interactions between Escherichia coli strains in human newborns and in gnotobiotic mice and piglets. Prog. Food Nutr. Sci. 7:107-116.
10. Duval-Iflah, Y., P. Raibaud, and M. Rousseau. 1981. Antagonisms among isogenic strains of Escherichia coli in the digestive tracts of gnotobiotic mice. Infect. Immun. 34:957-969.
11. FAO/WHO/OIE. 2007. Report of the Joint FAO/WHO/OIE Expert Meeting on Critically Important Antimicrobials. FAO, Rome, Italy.
12. CTX-M-9 gene from animal strains of Salmonella enterica Virchow to Escherichia coli in the human-faecal-flora-associated (HFF) rat model: impact of therapeutic doses of cefixime. Proc. 2nd Symp. Antimicrob. Resist. Anim. Environ.
13. Hasman, H., D. Mevius, K. Veldman, I. Olesen, and F. M. Aarestrup. 2005. Beta-lactamases among extended-spectrum beta-lactamase (ESBL)-resistant Salmonella from poultry, poultry products and human patients in The Netherlands. J. Antimicrob. Chemother. 56:115-121.
14. Hornish, R. E., and S. F. Kotarski. 2002. Cephalosporins in veterinary medicine - ceftiofur use in food animals. Curr. Top. Med. Chem. 2:717-731.
15. Jorgensen, C. J., L. M. Cavaco, H. Hasman, H. D. Emborg, and L. Guardabassi. 2007. Occurrence of CTX-M-1-producing Escherichia coli in pigs treated with ceftiofur. J. Antimicrob. Chemother. 59:1040-1042.
16. Lindgren, P. K., L. L. Marcusson, D. Sandvang, N. Frimodt-Moller, and D. Hughes. 2005. Biological cost of single and multiple norfloxacin resistance mutations in Escherichia coli implicated in urinary tract infections. Antimicrob. Agents Chemother. 49:2343-2351.
17. Liu, J. H., S. Y. Wei, J. Y. Ma, Z. L. Zeng, D. H. Lu, G. X. Yang, and Z. L. Chen. 2007. Detection and characterisation of CTX-M and CMY-2 betalactamases among Escherichia coli isolates from farm animals in Guangdong Province of China. Int. J. Antimicrob. Agents 29:576-581.
18. Livermore, D. M., R. Canton, M. Gniadkowski, P. Nordmann, G. M. Rossolini, G. Arlet, J. Ayala, T. M. Coque, I. Kern-Zdanowicz, F. Luzzaro, L. Poirel, and N. Woodford. 2007. CTX-M: changing the face of ESBLs in Europe. J. Antimicrob. Chemother. 59:165-174.
19. Meunier, D., E. Jouy, C. Lazizzera, M. Kobisch, and J. Y. Madec. 2006. CTX-M-1- and CTX-M-15-type beta-lactamases in clinical Escherichia coli isolates recovered from food-producing animals in France. Int. J. Antimicrob. Agents 28:402-407.
20. Paterson, D. L., and R. A. Bonomo. 2005. Extended-spectrum beta-lactamases: a clinical update. Clin. Microbiol. Rev. 18:657-686.
21. Wiuff, C., J. Lykkesfeldt, O. Svendsen, and F. M. Aarestrup. 2003. The effects of oral and intramuscular administration and dose escalation of enrofloxacin on the selection of quinolone resistance among Salmonella and coliforms in pigs. Res. Vet. Sci. 75:185-193.