Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation

Journal of Cell Biology

Volumn 214, Issue 6, 2016, Pages

  Chai, Ye Jin ^a   Sierecki, Emma ^a,b   Tomatis, Vanesa M ^a   Gormal, Rachel S ^a   Giles, Nichole ^a,b   Morrow, Isabel C ^a   Xia, Di ^a   Götz, Jürgen ^a   Parton, Robert G ^a   Collins, Brett M ^a   Gambin, Yann ^a,b   Meunier, Frédéric A ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; CHAPERONE; MUNC 18 1 PROTEIN; MUNC18 PROTEIN; UNCLASSIFIED DRUG; HYBRID PROTEIN; PROTEIN AGGREGATE; PROTEIN BINDING; SNCA PROTEIN, RAT; STXBP1 PROTEIN, RAT;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; LEWY BODY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; ANIMAL; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; GENETICS; GENOTYPE; HAPLOINSUFFICIENCY; METABOLISM; MOLECULAR MODEL; MUTATION; NERVE CELL; NERVE DEGENERATION; NEWBORN; PATHOLOGY; PC12 CELL LINE; PROTEIN CONFORMATION; RAT; RNA INTERFERENCE; SPRAGUE DAWLEY RAT; TIME FACTOR;

ALPHA-SYNUCLEIN; ANIMALS; ANIMALS, NEWBORN; GENOTYPE; HAPLOINSUFFICIENCY; LEWY BODIES; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MOLECULAR CHAPERONES; MUNC18 PROTEINS; MUTATION; NERVE DEGENERATION; NEURONS; PARKINSON DISEASE; PC12 CELLS; PROTEIN AGGREGATES; PROTEIN BINDING; PROTEIN CONFORMATION; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; TIME FACTORS; TRANSFECTION;

EID: 84991241072     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201512016     Document Type: Article

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