Alpha-2 adrenergic agonists for the prevention of shivering following general anaesthesia

Cochrane Database of Systematic Reviews

Volumn 2015, Issue 8, 2015, Pages

  Lewis, Sharon R ^a   Nicholson, Amanda ^b   Smith, Andrew F ^a   Alderson, Phil ^c  

^a ROYAL LANCASTER INFIRMARY   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; CLONIDINE; DEXMEDETOMIDINE; PLACEBO; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT;

BRADYCARDIA; COMPARATIVE EFFECTIVENESS; CORE TEMPERATURE; GENERAL ANESTHESIA; HUMAN; HYPOTENSION; HYPOTHERMIA; INADVERTENT PERIOPERATIVE HYPOTHERMIA; LENGTH OF STAY; META ANALYSIS; OUTCOME ASSESSMENT; PATIENT SATISFACTION; PLACEBO EFFECT; POSTANAESTHETIC CARE UNIT; POSTOPERATIVE ANALGESIA; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PUBLISHING; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECOVERY ROOM; REVIEW; RISK REDUCTION; SENSITIVITY ANALYSIS; SHIVERING; STUDY DESIGN; SURGICAL PATIENT; SYSTEMATIC REVIEW; TIME TO TREATMENT; ADULT; ADVERSE EFFECTS; DRUG EFFECTS;

ADRENERGIC ALPHA-AGONISTS; ADULT; ANESTHESIA, GENERAL; CLONIDINE; DEXMEDETOMIDINE; HUMANS; HYPOTHERMIA; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SHIVERING;

EID: 84991227405     PISSN: None     EISSN: 1469493X     Source Type: Journal    
DOI: 10.1002/14651858.CD011107.pub2     Document Type: Review

References (74)

1. Abdelmageed WM, Al Taher WM. Intramuscular dexmedetomidine for prevention of shivering after general anesthesia in patients undergoing arthroscopic anterior cruciate ligament reconstruction. Ain-Shams Journal of Anesthesiology 2014;07:156-62.
2. Aldehayat, G. Intraoperative dexmedetomidine administration at the end of surgery prevents post anesthetic shivering. Rawal Medical Journal 2011;36:274-6.
3. Bajwa SJS, Gupta S, Kaur J, Singh A, Parmar SS. Reduction in the incidence of shivering with perioperative dexmedetomidine: A randomized prospective study. Journal of Anaesthesiology Clinical Pharmacology 2012;28(1):86-91.
4. Bicer C, Esmaoglu A, Akin A, Boyaci A. Dexmedetomidine and meperidine prevent postanaesthetic shivering. European Journal of Anaesthesiology 2006;23(2):149-53. [PUBMED: 16426470]
5. Buggy D, Higgins P, Moran C, O'Donovan F, McCarroll M. Clonidine at induction reduces shivering after general anaesthesia. Canadian Journal of Anaesthesia 1997;44:263-7. [PUBMED: 9067044]
6. Delaunay L, Bonnet F, Duvaldestin P. Clonidine decreases postoperative oxygen consumption in patients recovering from general anaesthesia. British Journal of Anaesthesia 1991;67(4):397-401. [PUBMED: 1931396]
7. Elvan EG, Oc B, Uzun S, Karabulut E, Coskun F, Aypar U. Dexmedetomidine and postoperative shivering in patients undergoing elective abdominal hysterectomy. European Journal of Anaesthesiology 2008;25:357-64. [PUBMED: 18205960]
8. Frank T, Thieme V, Olthoff D. Preoperative clonidine comedication within the scope of balanced inhalation anesthesia with sevoflurane in oral surgery procedures. Anaesthesiologie und Reanimation 1999; Vol. 24, issue 3:65-70. [PUBMED: 10472699]
9. Grundmann U, Berg K, Stamminger U, Juckenhofel S, Wilhelm W. Comparison of pethidine and clonidine in the prevention of postoperative shivering. A prospective, randomised, placebo-controlled, double-blind study. Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie 1997;32(1):36-42. [CN-00199143]
10. Horn EP, Werner C, Sessler DI, Steinfath M, Schulte Am Esch J. Late intraoperative clonidine administration prevents postanesthetic shivering after total intravenous or volatile anesthesia. Anesthesia and Analgesia 1997;84:613-7. [PUBMED: 9052312]
11. Horn EP, Standl T, Sessler DI, Von Knobelsdorff G, Buchs C, Schulte J. Physostigmine prevents postanesthetic shivering as does meperidine or clonidine. Anesthesiology 1998;88:108-13. [PUBMED: 9447863]
12. Jabbary Moghaddam M, Ommi D, Mirkheshti A, Dabbagh A, Memary E, Sadeghi A, et al. Effects of clonidine premedication upon postoperative shivering and recovery time in patients with and without opium addiction after elective leg fracture surgeries. Anesthesiology and Pain Medicine 2013;2(3):107-10. [PUBMED: 24244918]
13. Karaman S, Gunusen I, Ceylan MA, Karaman Y, Cetin EN, Derbent A, et al. Dexmedetomidine infusion prevents postoperative shivering in patients undergoing gynecologic laparoscopic surgery. Turkish Journal of Medical Sciences 2013;43:232-7.
14. Kim YS, Kim YI, Seo KH, Kang HR. Optimal dose of prophylactic dexmedetomidine for preventing postoperative shivering. International Journal of Medical Sciences 2013;10(10):1327-32. [2013525857]
15. Mohammadi SS, Seyedi M. Effects of oral clonidine in preventing postoperative shivering after general anesthesia. International Journal of Pharmacology 2007;3:441-3.
16. Quintin L, Viale JP, Annat G, Hoen JP, Butin E, Cottet-Emard JM, et al. Oxygen uptake after major abdominal surgery: effect of clonidine. Anesthesiology 1991;74(2):236-41. [PUBMED: 1990899]
17. Sahin T, Kilickan L, Canatay H, Baykara N, Toker K. The effect of clonidine on postoperative shivering in sevoflurane anaesthetized patients. Turk Anesteziyoloji ve Reanimasyon 2002;30:203-8.
18. Sumpelmann R, Brauer A, Krohn S, Schroder D, Strauss JM. Effects of intravenous clonidine on recovery and postanaesthetic analgesic requirements. Der Schmerz 1994;8(1):51-6. [PUBMED: 18415455]
19. Vanderstappen I, Vandermeersch E, Vanacker B, Mattheussen M, Herijgers P, Van Aken H. The effect of prophylactic clonidine on postoperative shivering. A large prospective double-blind study. Anaesthesia 1996;51(4):351-5. [PUBMED: 8686824]
20. Yildiz TS, Baykara N, Bozkurt N, Oysu DA, Solak M, Toker K. The effect of clonidine on shivering in low flow desflurane anaesthesia. Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi 2005;33:29-35.
21. Apitzsch H, Olthoff D, Thieme V, Vetter B, Wiegel M. The effects of perioperative continuous administration of mivazerol on early postoperative hemodynamics and plasma catecholamines after major surgery. Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie 2000;35(8):515-22. [PUBMED: 10992963]
22. Arslan G, Güreler C, Köse HE, Yurdakoç A, Günday I. Comparison of tramadol and clonidine in prophylaxis of shivering after general anaesthesia. European Society of Anaesthesiologists 2000;17:15.
23. Bakhamees HS, El-Halafawy YM, El-Kerdawy HM, Gouda NM, Altemyatt S. Effects of dexmedetomidine in morbidly obese patients undergoing laparoscopic gastric bypass. Middle East Journal of Anesthesiology 2007;19:537-51. [PUBMED: 18044282]
24. Bernard JM, Bourréli B, Homméril JL, Pinaud M. Effects of oral clonidine premedication and postoperative i.v. infusion on haemodynamic and adrenergic responses during recovery from anaesthesia. Acta Anaesthesiologica Scandinavica 1991;35(1):54-9. [CN-00074018]
25. Bernard JM, Fulgencio JP, Delaunay L, Bonnet F. Clonidine does not impair redistribution hypothermia after the induction of anesthesia. Anesthesia and Analgesia 1998;87(1):168-72. [PUBMED: 9661568]
26. Eberhart LH, Novatchkov N, Schricker T, Georgieff M, Baur CP. Clonidine compared to midazolam for intravenous premedication for ambulatory procedures. A controlled double blind study in ASA 1 patients. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie 2000;35(6):388-93. [PUBMED: 10900497]
27. Gao GJ, Xu YY, Wang B, Lv HM, Yang WY, Shang Y. Feasibility of dexmedetomidine assisting sevoflurane for controlled hypotension in endoscopic sinus surgery. Medical Journal of Chinese People's Liberation Army 2012;37(1):45-8.
28. Hidalgo MP, Auzani JA, Rumpel LC, Moreira NL Jr, Cursino AW, Caumo W. The clinical effect of small oral clonidine doses on perioperative outcomes in patients undergoing abdominal hysterectomy. Anesthesia and Analgesia 2005;100:795-802. [PUBMED: 15728070]
29. Lee C, Kim YD, Kim JN. Antihyperalgesic effects of dexmedetomidine on high-dose remifentanil-induced hyperalgesia. Korean Journal of Anesthesiology 2013;64(4):301-7. [PUBMED: 23646238]
30. Mizobe T, Nakajima Y, Sunaguchi M, Ueno H, Sessler DI. Clonidine produces a dose-dependent impairment of baroreflex-mediated thermoregulatory responses to positive end-expiratory pressure in anaesthetized humans. British Journal of Anaesthesia 2005;94(4):536-41. [PUBMED: 15708868]
31. Onodera Y, Yamagishi A, Kunisawa T, Kurosawa A, Takahata O, Iwasaki H. Postoperative analgesia of continuous intravenous fentanyl or dexmedetomidine for patients receiving anticoagulant therapy. Masui 2011;60(8):936-40. [PUBMED: 21861419]
32. Piper SN, Maleck WH, Boldt J, Suttner SW, Schmidt CC, Reich DG. A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering. Anesthesia and Analgesia 2000;90(4):954-7. [PUBMED: 10735806]
33. Piper SN, Rohm KD, Maleck WH, Fent MT, Suttner SW, Boldt J. Dolasetron for preventing postanesthetic shivering. Anesthesia and Analgesia 2002;94(1):106-11. [PUBMED: 11772810]
34. Piper SN, Rohm KD, Suttner SW, Maleck WH, Kranke P, Boldt J. A comparison of nefopam and clonidine for the prevention of postanaesthetic shivering: a comparative, double-blind and placebo-controlled dose-ranging study. Anaesthesia 2004;59(6):559-64. [PUBMED: 15144295]
35. Quintin L, Roudot F, Roux C, Macquin I, Basmaciogullari A, Guyene T, et al. Effect of clonidine on the circulation and vasoactive hormones after aortic surgery. British Journal of Anaesthesia 1991;66(1):108-15. [PUBMED: 1997045]
36. Rohrbach A, Jage J, Olthoff D. Intraoperative clonidine modulates sympathetic tone in the early postoperative period after remifentanil. A double blind, placebo-controlled study. Acute Pain 1999;2:129-38.
37. Wright PM, Carabine UA, McClune S, Orr DA, Moore J. Preanaesthetic medication with clonidine. British Journal of Surgery 1990;65:628-32. [PUBMED: 2248839]
38. IRCT138902083773N2. Evaluation of oral clonidine effects on prevention of post-anesthesia shivering. http://www.irct.ir/searchresult.php?keyword=randomly&id=3773&field=&number=2&prt=885&total=4&m=1 (accessed 13 June 2014).
39. Alderson P, Campbell G, Smith AF, Warttig S, Nicholson A, Lewis SR. Thermal insulation for preventing inadvertent perioperative hypothermia. Cochrane Database of Systematic Reviews 2014, Issue 6. [DOI: 10.1002/14651858.CD009908.pub2]
40. Alfonsi P. Postanaesthetic shivering. Epidemiology, pathophysiology and approaches to prevention and management. Minerva Anestesiologica 2003;69(5):438-42. [PUBMED: 12768180]
41. Biccard BM, Goga S, de Beurs J. Dexmedetomidine and cardiac protection for non-cardiac surgery: a meta-analysis of randomised controlled trials. Anaesthesia 2008;63(1):4-14. [PUBMED: 18086064]
42. Brenner GM, Stevens CW. Pharmacology. Philadelphia, PA: Elsevier/Saunders, 2013.
43. Buggy DJ, Crossley AW. Thermoregulation, mild perioperative hypothermia and postanaesthetic shivering. British Journal of Anaesthesia 2000; Vol. 84, issue 5:615-28. [PUBMED: 10844839]
44. Campbell G, Alderson P, Smith AF, Warttig S. Warming of intravenous and irrigation fluids for preventing inadvertent perioperative hypothermia. Cochrane Database of Systematic Reviews 2012, Issue 6. [DOI: 10.1002/14651858.CD009891]
45. Crossley AW, Mahajan RP. The intensity of postoperative shivering is unrelated to axillary temperature. Anaesthesia 1994;49(3):205-7. [PUBMED: 8147511]
46. De Witte J, Sessler DI. Perioperative shivering: physiology and pharmacology. Anesthesiology 2002;96(2):467-84. [PUBMED: 11818783]
47. Eberhart LHJ, Döderlein F, Eisenhardt G, Kranke P, Sessler DI, Torossian A, et al. Independent risk factors for postoperative shivering. Anesthesia and Analgesia 2005;101(6):1849-57. [PUBMED: 16301273]
48. GRADE Working Group 2004-2011. GRADEprofiler. Available at http://www.gradepro.org/gradepro/, 2015.
49. Guyatt GH, Oxman AD, Kunz R, Vist GE, Falck-Ytter Y, Schunemann HJ. What is "quality of evidence" and why is it important to clinicians?. BMJ 2008;336(7651):995-8. [PUBMED: 18456631]
50. Harper CM, Andrzejowski JC, Alexander R. NICE and warm. British Journal of Anaesthesia 2008;101(3):293-5. [PUBMED: 18710834]
51. Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
52. Higgins JPT, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ 2011;343:d5928. [PUBMED: 22008217]
53. Horosz B, Malec-Milewska M. Inadvertent intraoperative hypothermia. Anaesthesiology Intensive Therapy 2013;45(1):38-43. [PUBMED: 23572308]
54. Jalonen J, Hynynen M, Kuitunen A, Heikkila H, Perttila J, Salmenpera M, et al. Dexmedetomidine as an anesthetic adjunct in coronary artery bypass grafting. Anesthesiology 1997;86(2):331-45. [PUBMED: 9054252]
55. Kamibayashi T, Maze M. Clinical uses of alpha-2-adrenergic agonists. Anesthesiology 2000;93(5):1345-9. [PUBMED: 11046225]
56. Kim Y, Seo K. Optimal dose of prophylactic dexmedetomidine in preventing postoperative shivering. Anesthesia and Analgesia 2013;116:S-45.
57. Kranke P, Eberhart LH, Roewer N, Tramer MR. Single-dose parenteral pharmacological interventions for the prevention of postoperative shivering: a quantitative systematic review of randomized controlled trials. Anesthesia and Analgesia 2004;99(3):718-27, table of contents. [PUBMED: 15333401]
58. Kurz A, Sessler DI, Christensen R, Dechert M. Heat balance and distribution during the core-temperature plateau in anesthetized humans. Anesthesiology 1995;83(3):491-9. [PUBMED: 7661349]
59. Macario A, Weinger M, Carney S, Kim A. Which clinical anesthesia outcomes are important to avoid? The perspective of patients. Anesthesia and Analgesia 1999;89(3):652-8. [PUBMED: 10475299]
60. Macario A, Weinger M, Truong P, Lee M. Which clinical anesthesia outcomes are both common and important to avoid? The perspective of a panel of expert anesthesiologists. Anesthesia and Analgesia 1999; Vol. 88, issue 5:1085-91. [PUBMED: 10320175]
61. National Institute for Health and Clinical Excellence. The management of inadvertent perioperative hypothermia in adults. Clinical Guideline CG65. http://www.nice.org.uk/guidance/CG65/NiceGuidance/pdf/English (accessed 19 November 2013).
62. Nishina K, Mikawa K, Uesugi T, Obara H, Maekawa M, Kamae I, et al. Efficacy of clonidine for prevention of perioperative myocardial ischemia: a critical appraisal and meta-analysis of the literature. Anesthesiology 2002;96(2):323-9. [PUBMED: 11818763]
63. Park SM, Mangat HS, Berger K, Rosengart AJ. Efficacy spectrum of antishivering medications: Meta-analysis of randomized controlled trials. Critical Care Medicine 2012;40(11):3070-82. [PUBMED: 22890247 ]
64. No authors listed. A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering: Retraction. Anesthesia and Analgesia 2011;112(5):1225. [PUBMED: 21451076]
65. No authors listed. Dolasetron for preventing postanesthetic shivering: Retraction. Anesthesia and Analgesia 2011; Vol. 112, issue 5:1211. [PUBMED: 21451086]
66. No authors listed. A comparison of nefopam and clonidine for the prevention of postanaesthetic shivering: a comparative, double-blind and placebo-controlled dose-ranging study: Retraction. Anaesthesia 2011;66(7):646. [PUBMED: 21826809]
67. The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014.
68. Smith AF. In search of excellence in anesthesiology. Anesthesiology 2009;110:4-5. [DOI: 10.1097/ALN.0b013e318190b263]
69. Smith AF, Glavin R, Greaves JD. Defining excellence in anaesthesia: the role of personal qualities and practice environment. British Journal of Anaesthesia 2011;106:38-43.
70. Urrútia G, Roqué i Figuls M, Campos JM, Paniagua P, Cibrian Sánchez S, Maestre L, et al. Active warming systems for preventing inadvertent perioperative hypothermia in adults. Cochrane Database of Systematic Reviews 2011, Issue 3. [DOI: 10.1002/14651858.CD009016]
71. Warttig S, Alderson P, Campbell G, Smith AF. Interventions for treating inadvertent postoperative hypothermia. Cochrane Database of Systematic Reviews 2014, Issue 11. [DOI: 10.1002/14651858.CD009892]
72. Warttig S, Alderson P, Lewis SR, Smith AF. Intravenous nutrients for preventing inadvertent perioperative hypothermia. Cochrane Database of Systematic Reviews 2012, Issue 6. [DOI: 10.1002/14651858.CD009906]
73. Wijeysundera DN, Bender JS, Beattie WS. Alpha-2 adrenergic agonists for the prevention of cardiac complications among patients undergoing surgery. Cochrane Database of Systematic Reviews 2009, Issue 4. [DOI: 10.1002/14651858.CD004126.pub2]
74. Nicholson A, Lewis SR, Alderson P, Smith AF. Alpha-2 adrenergic agonists for the prevention of shivering following general anaesthesia. Cochrane Database of Systematic Reviews 2014, Issue 5. [DOI: 10.1002/14651858.CD011107]